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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
SD-Rag2em3McwiIl2rgem2Mcwi Resource Report Resource Website |
RRID:RGD_13207516 | Rattus norvegicus | This strain was produced by crossing of SD-Rag2em3Mcwi and SD-Il2rgem2Mcwi. Contact MCW rat distribution at [email protected] | 13207516 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207516 | 2026-09-12 01:25:33 | 0 | |||||
|
SD-Lepem1Sage-/- Resource Report Resource Website |
RRID:RGD_12904912 | Rattus norvegicus | This ZFN model possesses a 151 bp deletion spanning exon 1/intron 1 junction of Leptin gene. Homozygous knockout rats display loss of Leptin protein via Western blot. Homozygous knockout rats demonstrate significant weight gain compared to wild type littermates. Homozygous knockout rats show significantly elevated serum cholesterol levels Inotiv | 12904912 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-24) | 12904912 | 2026-09-12 01:25:33 | 0 | |||||
|
SS-P2rx7em13Mcwi Resource Report Resource Website |
RRID:RGD_13506832 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2rx7 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is an 10-bp putative frame-shift deletion in exon 2 Contact MCW rat distribution at [email protected] | 13506832 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13506832 | 2026-09-12 01:25:33 | 0 | |||||
|
SS-P2rx7em10Mcwi Resource Report Resource Website |
RRID:RGD_13506831 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2rx7 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is an 11-bp putative frame-shift deletion in exon 2 Contact MCW rat distribution at [email protected] | 13506831 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-02-21) | 13506831 | 2026-09-12 01:25:33 | 0 | |||||
|
SD-Slc22a2em1Sage Resource Report Resource Website |
RRID:RGD_12904891 | Rattus norvegicus | This ZFN model carries the knockout of the rat Slc22a2. Horizon Discovery | 12904891 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-24) | 12904891 | 2026-09-12 01:25:33 | 0 | |||||
|
SD-Slc22a6em1Sage Resource Report Resource Website |
RRID:RGD_12904892 | Rattus norvegicus | This ZFN model carries the knockout of the rat Slc22a6. Horizon Discovery | 12904892 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-24) | 12904892 | 2026-09-12 01:25:33 | 0 | |||||
|
SD-Tp53em1Sage Resource Report Resource Website |
RRID:RGD_12904897 | Rattus norvegicus | This ZFN model carries the monoallelic 11 base pair deletion in Tp53 gene. Animals exhibit broad tumor spectrum with high degree of tumor malignancy. Horizon Discovery | 12904897 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2024-04-16) | 12904897 | 2026-09-12 01:25:33 | 0 | |||||
|
SD-Lepem1 Resource Report Resource Website |
RRID:RGD_13210578 | Rattus norvegicus | This CRISPR/Cas9 model possesses a 3 bp(ATC) deletion resulting in the deletion of isoleucine at position 14. The Lep mutant rats exhibited similar mutant phenotypes to Lep and Lepr null rats. | 13210578 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13210578 | 2026-09-12 01:25:34 | 0 | |||||
|
FHH-Mybphlem2Mcwi Resource Report Resource Website |
RRID:RGD_13800845 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of rat Mybphl gene in the FHH/EurMcwi embryos. embryos. Contact MCW rat distribution at [email protected] | 13800845 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2023-06-21) | 13800845 | 2026-09-12 01:25:35 | 0 | |||||
|
SS-P2rx7em12Mcwi Resource Report Resource Website |
RRID:RGD_13792803 | Rattus norvegicus | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 10-bp deletion in Exon 2 of the P2rx7 gene. | 13792803 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2023-06-21) | 13792803 | 2026-09-12 01:25:35 | 0 | |||||
|
SS-Nlrp3em2Mcwi Resource Report Resource Website |
RRID:RGD_13792801 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion of exon 1 in the Nlrp3 gene. Contact MCW rat distribution at [email protected] | 13792801 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-09-28) | 13792801 | 2026-09-12 01:25:35 | 0 | |||||
|
SD-Ldlrem1 Resource Report Resource Website |
RRID:RGD_12910101 | Rattus norvegicus | This model possesses a 19-bp deletion in the seventh exon of the ldlr gene by ZFN method. | 12910101 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12910101 | 2026-09-12 01:25:34 | 0 | |||||
|
WI-Abcb1aem3Sage Resource Report Resource Website |
RRID:RGD_12907570 | Rattus norvegicus | This model contains one 19- bp deletion and one 428-bp deletion within Abcba1 gene. The homozygous knockout rats display total loss of protein via Western blot. | 12907570 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12907570 | 2026-09-12 01:25:34 | 0 | |||||
|
WI-Abcb1aem2Sage Resource Report Resource Website |
RRID:RGD_12907568 | Rattus norvegicus | This model contains biallelic 19- bp deletion in exon 7 of Abcba1 gene. The homozygous knockout rats display total loss of protein via Western blot. | 12907568 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12907568 | 2026-09-12 01:25:34 | 0 | |||||
|
SS-Kcnj1em1Kasu+/+ Resource Report Resource Website |
RRID:RGD_13782280 | Rattus norvegicus | Zinc Finger Nuclease (ZFN) was utilized to knockout rat Kcnj1 function. ZFN constructs targeting the gene were designed and purchased from Sigma Aldrich (St. Louis, MO, USA). The targeting site sequence is CTCAAGTGACCATAGGTTACGgattcaGGTTTGTGAC (lower case represents the ZFN cleavage site). Kcnj1 knockout founders were generated by microinjection of ZFN mRNAs into single-cell SS (from Harlan) rat embryos. The resulting mutation is 209 bp deletion from G225 to G433, leading to frameshift and premature termination of Kcnj1 protein. This strain is the wild type littermate from heterozygous cross. | 13782280 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13782280 | 2026-09-12 01:25:35 | 0 | |||||
|
BN-KitWs Resource Report Resource Website |
RRID:RGD_12910762 | Rattus norvegicus | A spontaneous mutant male with a large white spot and coat color dilution was identified in the BN/fMai colony in Yagi Memorial Park (kani-gun, Japan). | 12910762 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12910762 | 2026-09-12 01:25:35 | 0 | |||||
|
SD-Leprem3 Resource Report Resource Website |
RRID:RGD_12910519 | Rattus norvegicus | This strain was produced by injecting TALEN targeting the sequence of rat Lepr into SD embryos. The resulting mutation is a 18-bp insertion. | 12910519 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12910519 | 2026-09-12 01:25:34 | 0 | |||||
|
SD-Leprem1 Resource Report Resource Website |
RRID:RGD_12910514 | Rattus norvegicus | This strain was produced by injecting TALEN targeting the sequence of rat Lepr into SD embryos. The resulting mutation is a 57-bp deletion. | 12910514 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12910514 | 2026-09-12 01:25:34 | 0 | |||||
|
SD-Rnaset2em1Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_13781890 | Rattus norvegicus | Two pairs of CRISPR guide RNAs were designed to cleave together to delete all 9 exons of RNaseT2. The CRISPR guide RNA and Cas9 mRNA mixtures were microinjected into the pronuclei of fertilized embryos of Sprague-Dawley rats and transferred to pseudopregnant female rats. WT, heterozygous and homozygous (KO) rats were born in the expected Mendelian ratio, and homozygous RNaseT2 KO rats were viable and fertile. | 13781890 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13781890 | 2026-09-12 01:25:35 | 1 | |||||
|
SS-Ptk2bem1Mcwi Resource Report Resource Website |
RRID:RGD_13792808 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Ptk2b gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 8-bp deletion in exon 2. | 13792808 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13792808 | 2026-09-12 01:25:35 | 0 |
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