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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040505
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: sprSi1 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:WRM1, CGC_WRM1
Notes: Made_by: John Pagano|"sprSi1 [pie-1p::GFP::histone-H2B::nos-2(MRE mut) 3'UTR + Cbr-unc-119(+)] II. Nuclear GFP fluorescence in germline progenitor cells in early embryos. Reference: Pagano JM, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20252-7."
Proper citation: RRID:WB-STRAIN:WBStrain00040505 Copy
http://www.wormbase.org/db/get?name=WBStrain00040502
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33820969, PMID:38564369
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:WN2064
Notes: Added Wild_Isolate tag as Isolation information is available suggesting that they were sampled from the wild.
Proper citation: RRID:WB-STRAIN:WBStrain00040502 Copy
http://www.wormbase.org/db/get?name=WBStrain00040504
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33820969, PMID:38564369
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:WN2066
Notes: Added Wild_Isolate tag as Isolation information is available suggesting that they were sampled from the wild.
Proper citation: RRID:WB-STRAIN:WBStrain00040504 Copy
http://www.wormbase.org/db/get?name=WBStrain00040568
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:38177158
Synonyms: unc-119(ed3) III; wtEx30.
Alternate IDs: WB-STRAIN:WT30, CGC_WT30
Notes: wtEx30 [cuti-1p::cuti-1::GFP + unc-119(+)]. Maintain by picking non-Unc. Reference: Fritz JA & Behm CA. PLoS One. 2009;4(4):e5117.
Proper citation: RRID:WB-STRAIN:WBStrain00040568 Copy
http://www.wormbase.org/db/get?name=WBStrain00040530
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00002042(hus-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00002042(hus-1)
Availability: available
Source References: EMPTY
Synonyms: hus-1(op244) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:WS2265, CGC_WS2265
Notes: Heterozygotes are WT GFP+ and segregate non-glowing hus-1 homozygotes and very rare homozygous hT2 glowing animals, and dead eggs. qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and gut promoter driving GFP in the intestine. hus-1(op244) mutants from homozygous parents show an incompletely penetrant maternal effect embryonic lethality. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype.
Proper citation: RRID:WB-STRAIN:WBStrain00040530 Copy
http://www.wormbase.org/db/get?name=WBStrain00040547
Source Database: WormBase (WB)
Affected Genes: WBGene00000390(cdc-42)
Genomic Alteration: WBGene00000390(cdc-42)
Availability: available
Source References: EMPTY
Synonyms: cdc-42(gk388) opIs295 II.
Alternate IDs: WB-STRAIN:WS5018, CGC_WS5018
Notes: opIs295 [cdc-42p::GFP::cdc-42(genomic)::cdc-42 3'UTR + unc-119(+)] II. opIs295 fully rescues cdc-42 animals.
Proper citation: RRID:WB-STRAIN:WBStrain00040547 Copy
http://www.wormbase.org/db/get?name=WBStrain00040670
Source Database: WormBase (WB)
Affected Genes: WBGene00000018(abl-1)
Genomic Alteration: WBGene00000018(abl-1)
Availability: available
Source References: PMID:37620393, PMID:37838776
Synonyms: abl-1(ok171) X.
Alternate IDs: WB-STRAIN:XR1, CGC_XR1
Notes: 1.5 kb of M79.1 locus is deleted which corresponds to the elimination of exons 8-12, including the kinase domain and 2/3 of the SH2 domains.|"Mutagen:UV/TMP"|"Supplementary_genotype abl-1(ok171),"
Proper citation: RRID:WB-STRAIN:WBStrain00040670 Copy
http://www.wormbase.org/db/get?name=WBStrain00040608
Source Database: WormBase (WB)
Affected Genes: WBGene00000528(clh-1)
Genomic Alteration: WBGene00000528(clh-1)
Availability: available
Source References: PMID:10610763
Synonyms: clh-1(qa900) II.
Alternate IDs: WB-STRAIN:XA900, CGC_XA900
Notes: Exhibit wider body and abnormal alae structure.|"Made_by: Mark I.R. Petalcorin"
Proper citation: RRID:WB-STRAIN:WBStrain00040608 Copy
http://www.wormbase.org/db/get?name=WBStrain00040650
Source Database: WormBase (WB)
Affected Genes: WBGene00001332(eri-1)|WBGene00003004(lin-15)|WBGene00004323(rde-1)|WBGene00023497(lin-15B)
Genomic Alteration: WBGene00001332(eri-1), WBGene00003004(lin-15), WBGene00004323(rde-1), WBGene00023497(lin-15B)
Availability: available
Source References: PMID:38177330
Synonyms: wpIs36 I; wpSi1 II; eri-1(mg366) IV; rde-1(ne219) V; lin-15B(n744) X.
Alternate IDs: WB-STRAIN:XE1375, CGC_XE1375
Notes: Made_by: C. Firnhaber|"Mutagen:TMP+UV"|"Mutagen:TMP/UV"|"wpIs36 [unc-47p::mCherry] I. wpSi1 [unc-47p::rde-1::SL2::sid-1 + Cbr-unc-119(+)] II. Maintain at 15-20C, sterile at 25C. GABAergic neuron-specific RNAi strain. Sensitivity to feeding RNAi is limited to the GABAergic neurons; all other tissues are resistant to RNAi. Superficially wild type with mCherry fluorescence in the GABA motor neurons. Reference: Firnhaber C & Hammarlund M. PLoS Genet. 2013 Nov;9(11):e1003921."
Proper citation: RRID:WB-STRAIN:WBStrain00040650 Copy
http://www.wormbase.org/db/get?name=WBStrain00040755
Source Database: WormBase (WB)
Affected Genes: WBGene00011333(nrde-2)
Genomic Alteration: WBGene00011333(nrde-2)
Availability: available
Source References: PMID:33594200
Synonyms: nrde-2(gg95) II.
Alternate IDs: WB-STRAIN:YY156, CGC_YY156
Notes: Reference: Guang S, et al. Nature. 2010 Jun 24;465(7301):1097-101.
Proper citation: RRID:WB-STRAIN:WBStrain00040755 Copy
http://www.wormbase.org/db/get?name=WBStrain00040757
Source Database: WormBase (WB)
Affected Genes: WBGene00007577(nrde-1)
Genomic Alteration: WBGene00007577(nrde-1)
Availability: available
Source References: PMID:33594200
Synonyms: nrde-1(gg88) III.
Alternate IDs: WB-STRAIN:YY160, CGC_YY160
Notes: eri-1(mg366) has been crossed out of the background. Reference: Burkhart KB, et al. PLoS Genet. 2011 Aug;7(8):e1002249.
Proper citation: RRID:WB-STRAIN:WBStrain00040757 Copy
http://www.wormbase.org/db/get?name=WBStrain00040751
Source Database: WormBase (WB)
Affected Genes: WBGene00000793(crh-1)
Genomic Alteration: WBGene00000793(crh-1)
Availability: available
Source References: EMPTY
Synonyms: crh-1(tz2) III.
Alternate IDs: WB-STRAIN:YT17, CGC_YT17
Notes: Clumpy, pale and slightly small, tend to dig into plate. Daf-c at 27C. Do not distribute this strain; other labs should request it from the CGC.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040751 Copy
http://www.wormbase.org/db/get?name=WBStrain00040769
Source Database: WormBase (WB)
Affected Genes: WBGene00003992(pgl-1)|WBGene00014208(znfx-1)
Genomic Alteration: WBGene00003992(pgl-1), WBGene00014208(znfx-1)
Availability: available
Source References: PMID:33438773, PMID:37749091
Synonyms: znfx-1(gg544[3xflag::gfp::znfx-1]) II; pgl-1(gg547[pgl-1::3xflag::tagRFP]) IV.
Alternate IDs: WB-STRAIN:YY968, CGC_YY968
Notes: 3xflag::gfp inserted into endogenous znfx-1 locus, and 3xflag::tagRFP inserted into endogenous pgl-1 locus using CRISPR/Cas9 engineering. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683.
Proper citation: RRID:WB-STRAIN:WBStrain00040769 Copy
http://www.wormbase.org/db/get?name=WBStrain00040731
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; vrEx6.
Alternate IDs: WB-STRAIN:YL206, CGC_YL206
Notes: vrEx6 [nst-1p::nst-1::GFP::nst-1 3' UTR + unc-119(+)]. Stable array; high transmission rate and low percentage of mosaicism. Maintain by picking wild-type. Reference: Kudron et al. (2008) PLos Genet 4(8):e1000181.
Proper citation: RRID:WB-STRAIN:WBStrain00040731 Copy
http://www.wormbase.org/db/get?name=WBStrain00040714
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00010056(smc-6)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00010056(smc-6)
Availability: available
Source References: PMID:39115289
Synonyms: smc-6(ok3294)/mIn1 [mIs14 dpy-10(e128)] II.
Alternate IDs: WB-STRAIN:YE58, CGC_YE58
Notes: Homozygous viable mutation balanced by GFP- and dpy-10-marked inversion. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP, Dpy bright GFP (mIn1 homozygotes), and non-GFP ok3294 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain. ok3294 homozygotes are morphologically wild-type but show ~30% reduction in fertilized eggs and a trans-generational increase in sterility. Maintain under normal conditions. Reference: Bickel JS, et al. PLoS Genet. 2010 Jul 22;6(7):e1001028.|"Made_by: Jeremy Bickel"
Proper citation: RRID:WB-STRAIN:WBStrain00040714 Copy
http://www.wormbase.org/db/get?name=WBStrain00040793
Source Database: WormBase (WB)
Affected Genes: WBGene00001620(glt-1)|WBGene00001621(glt-3)
Genomic Alteration: WBGene00001620(glt-1), WBGene00001621(glt-3)
Availability: available
Source References: PMID:31306683
Synonyms: glt-3(bz34) IV; glt-1(ok206) X.
Alternate IDs: WB-STRAIN:ZB1106, CGC_ZB1106
Notes: Reference: Mano et al. (2007) J Biol Chem 282(47):34412-9.
Proper citation: RRID:WB-STRAIN:WBStrain00040793 Copy
http://www.wormbase.org/db/get?name=WBStrain00040712
Source Database: WormBase (WB)
Affected Genes: WBGene00007395(dcar-1)
Genomic Alteration: WBGene00007395(dcar-1)
Availability: available
Source References: EMPTY
Synonyms: dcar-1(tm2484) V.
Alternate IDs: WB-STRAIN:YC307, CGC_YC307
Notes: Defective avoidance to water-soluble repellent. Reference: Aoki R., et al. J Neurosci. 2011 Nov 16;31(46):16603-10.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00040712 Copy
http://www.wormbase.org/db/get?name=WBStrain00040770
Source Database: WormBase (WB)
Affected Genes: WBGene00014208(znfx-1)
Genomic Alteration: WBGene00014208(znfx-1)
Availability: available
Source References: PMID:37878696
Synonyms: znfx-1(gg561) II.
Alternate IDs: WB-STRAIN:YY996, CGC_YY996
Notes: Heritable RNAi defective, germline immortality. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683.|"Supplementary_genotype znfx-1(gg561)"
Proper citation: RRID:WB-STRAIN:WBStrain00040770 Copy
http://www.wormbase.org/db/get?name=WBStrain00040772
Source Database: WormBase (WB)
Affected Genes: WBGene00014208(znfx-1)
Genomic Alteration: WBGene00014208(znfx-1)
Availability: available
Source References: PMID:37505984, PMID:37537842, PMID:39179648
Synonyms: znfx-1(gg634[HA::tagRFP::znfx-1]) II.
Alternate IDs: WB-STRAIN:YY1446, CGC_YY1446
Notes: Alt Genotype: znfx-1(gg634[HA::tagRFP::znfx-1]) II|"Contains Construct ref. Wan G. et al. Nature 2018"|"HA::tagRFP inserted into endogenous znfx-1 locus using CRISPR/Cas9 engineering. Reference: Wan G, et al. Nature. 2018 May;557(7707):679-683."|"N-terminal HA::tagRFP tag on endogenous znfx-1"
Proper citation: RRID:WB-STRAIN:WBStrain00040772 Copy
http://www.wormbase.org/db/get?name=WBStrain00040781
Source Database: WormBase (WB)
Affected Genes: WBGene00000802(crt-1)
Genomic Alteration: WBGene00000802(crt-1)
Availability: available
Source References: EMPTY
Synonyms: crt-1(bz29) V.
Alternate IDs: WB-STRAIN:ZB1028, CGC_ZB1028
Notes: Probably null calreticulin. W28 amber. Slow growth (one day developmental delay). Nearly sterile if raised at 25C. Suppresses mec-4(d)-induced neurodegeneration. Bent-head.
Proper citation: RRID:WB-STRAIN:WBStrain00040781 Copy
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