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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SD-Tg(Sycp1-Cas9-eGFP)SynblRrrc Resource Report Resource Website |
RRID:RGD_155260361 | Rattus norvegicus | This project entailed generation of a novel rat strain in which a P2A-Cas9-T2A-EGFP coding sequence was inserted at the stop codon of the rat Sycp1 gene for co-expression of Cas9 and EGFP under the control of the Sycp1 regulatory elements. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 from RRRC. | 155260361 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2022-10-06) | 155260361 | 2026-08-29 11:49:59 | 0 | |||||
|
SD-Tg(Cyp2e1-CYP2E1*-Cas9)SynblRrrc Resource Report Resource Website |
RRID:RGD_155260363 | Rattus norvegicus | rat strain in which the rat Cyp2e1 gene is humanized by insertion of a human CYP2E1 minigene (CYP2E1*) insert at the native start codon. The insert also included a CRISPR/Cas9 gene drive element to enable super-Mendelian inheritance of the modified allele when crossed to a rat expressing Cas9 in the germline. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951 URL: URL: Doi:10.1101/2022.08.30.505951 RRRC | 155260363 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2022-10-06) | 155260363 | 2026-08-29 11:49:59 | 0 | |||||
|
SD-Tg(Ddx4-Cas9)Synbl Resource Report Resource Website |
RRID:RGD_155260366 | Rattus norvegicus | rat strain designed to express Cas9 under the control of the rat Ddx4 (Vasa) regulatory elements while also retaining expression of Ddx4. The strategy entailed insertion of a P2A sequence followed by human-codon-optimized Cas9 coding sequences with nuclear localization signals near the C-terminus of the rat Ddx4 (Vasa) gene. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951 Donated to Rat Resource & Research Center | 155260366 | transgenic | Rat Genome Database (RGD) | RGD | Unknown | 155260366 | 2026-08-29 11:49:59 | 0 | |||||
|
SD-Tg(Cyp3a23-3a1-Cyp3A4*-Cas9)Synb Resource Report Resource Website |
RRID:RGD_155260368 | Rattus norvegicus | rat strain in which the rat Cyp3a1 gene (Cyp3a23-3a1, RGD:628626) was inactivated by insertion of a human CYP3A4 minigene (Cyp3A4*) and the linked rat Cyp3a2 locus was simultaneously mutated by CRISPR-mediated indel introduction. Strain contains Indel 8 at the Rat 3A2 locus (55 kb away), The CYP3A4 minigene included a CRISPR/Cas9 gene drive element to enable super-Mendelian inheritance. Strain contains and Active Genetic cassette which encodes a gRNA targeting the Rat 3A1 and 3A2 translation initiation site. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951 URL: URL: Doi:10.1101/2022.08.30.505951 Donated to Rat Resource & Research Center | 155260368 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2022-10-06) | 155260368 | 2026-08-29 11:49:59 | 0 | |||||
|
SD-Tg(Cyp2e1-CYP2E1*-Cas9)Synbl Resource Report Resource Website |
RRID:RGD_155260367 | Rattus norvegicus | rat strain in which the rat Cyp2e1 gene is humanized by insertion of a human CYP2E1 minigene (CYP2E1*) insert at the native start codon. The insert also included a CRISPR/Cas9 gene drive element to enable super-Mendelian inheritance of the modified allele when crossed to a rat expressing Cas9 in the germline. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951 URL: URL: Doi:10.1101/2022.08.30.505951 Donated to Rat Resource & Research Center | 155260367 | transgenic | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2022-10-06) | 155260367 | 2026-08-29 11:49:59 | 0 | |||||
|
BN/Rij Resource Report Resource Website |
RRID:RGD_155804258 | Rattus norvegicus | inbred Brown Norway (BN) rat strain produced in the Rijswijk colony. | 155804258 | inbred | Rat Genome Database (RGD) | RGD | Unknown | 155804258 | 2026-08-29 11:49:59 | 0 | |||||
|
FXLE14/StmMcwi Resource Report Resource Website |
RRID:RGD_156430095 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430095 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430095 | 2026-08-29 11:49:59 | 0 | |||||
|
LEXF11/StmMcwi Resource Report Resource Website |
RRID:RGD_156430093 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430093 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430093 | 2026-08-29 11:49:59 | 0 | |||||
|
LEXF10C/StmMcwi Resource Report Resource Website |
RRID:RGD_156430092 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430092 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430092 | 2026-08-29 11:49:58 | 0 | |||||
|
LEXF10B/StmMcwi Resource Report Resource Website |
RRID:RGD_156430091 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430091 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430091 | 2026-08-29 11:49:58 | 0 | |||||
|
LEXF9/StmMcwi Resource Report Resource Website |
RRID:RGD_156430090 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430090 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430090 | 2026-08-29 11:49:59 | 0 | |||||
|
LEXF7C/StmMcwi Resource Report Resource Website |
RRID:RGD_156430086 | Rattus norvegicus | This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj. This substrain was maintained at Medical College of Wisconsin RGD HRDP, contact HRDP | 156430086 | recombinant_inbred | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2023-10-24) | 156430086 | 2026-08-29 11:49:58 | 0 | |||||
|
SD-Bmal1em1Mcwi Resource Report Resource Website |
RRID:RGD_155598601 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 58-base pair deletion in exon 6 in the rat Bmal1 gene of Crl:SD embryos. The deletion caused a premature stop codon in exon 6 resulting in a severe truncation of the Bmal1 protein. Contact MCW rat distribution at [email protected] | 155598601 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155598601 | 2026-08-29 11:49:59 | 0 | |||||
|
SS-Chr3BN.SS-(D3Rat36-D3Rat156)/Mcwi Resource Report Resource Website |
RRID:RGD_155782885 | Rattus norvegicus | SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability. | 155782885 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 155782885 | 2026-08-29 11:49:59 | 0 | |||||
|
SS-Chr3BN.SS-(D3Rat222-D3Rat218)/Mcwi Resource Report Resource Website |
RRID:RGD_155782881 | Rattus norvegicus | SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability. | 155782881 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 155782881 | 2026-08-29 11:49:59 | 0 | |||||
|
SS-Chr 3BN.SS-(D3Arb3-D3Rat93)( D3Rat78-D3Rat1)/Mcwi Resource Report Resource Website |
RRID:RGD_155782880 | Rattus norvegicus | SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability. | 155782880 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 155782880 | 2026-08-29 11:49:59 | 0 | |||||
|
SD-Pde6bem1Cgen Resource Report Resource Website |
RRID:RGD_155631289 | Rattus norvegicus | This mutant strain was generated by microinjecting CRISPRs/Cas9 system targeting rat Pde6b. Pde6b knock out rat was successfully created. Cyagen Biosciences Inc, Santa Clara, CA, USA | 155631289 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155631289 | 2026-08-29 11:49:58 | 0 | |||||
|
CD-Ctnsem3Vjupk Resource Report Resource Website |
RRID:RGD_155630633 | Rattus norvegicus | The mutant rat was produced by injecting Crl:CD(SD) zygotes with gRNA +Cas9 ribonucleoprotein complex targeting exon 3 of rat Ctns. The founder of this strain possessed a 8-bp insertion which results in frameshift and pre-mature stop truncated protein. | 155630633 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155630633 | 2026-08-29 11:49:58 | 0 | |||||
|
SD-Tg(MECP2 )Chnsr Resource Report Resource Website |
RRID:RGD_155631285 | Rattus norvegicus | PAC671D9 (AF031078) DNA containing all the exons of human MECP2 was injected to SD embryos to generate MECP2 duplication rat. | 155631285 | transgenic | Rat Genome Database (RGD) | RGD | Unknown | 155631285 | 2026-08-29 11:49:59 | 0 | |||||
|
SS-Chr3BN.SS-(D3Rat217- D3Mgh30)/Mcwi Resource Report Resource Website |
RRID:RGD_155782914 | Rattus norvegicus | SS/JrHsdMcwi were crossed with SS-3BN/Mcwi, rats from F1 were intercrossed and genotyped to select the congenic strain carrying introgressed chromosome 3 from SS to BN. Contact MCW rat distribution at [email protected] for availability. | 155782914 | congenic | Rat Genome Database (RGD) | RGD | Unknown | 155782914 | 2026-08-29 11:49:58 | 0 |
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