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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13524863
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 13524863
Notes: The LEC/Crlj is available at Japan Charles River Inc. (Yokohama, Japan) since 1991 from the Center for Experimental Plants and Animals, Hokkaido University.
Proper citation: RRID:RGD_13524863 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800555
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 13800555
Notes: From mating #344 of rats purchased from a local breeder (Fischer). The colony was originated by M. R. Curtis, Columbia University in 1920. To the Germ-Free Animal Laboratory at CNRS, Gif-sur-Yvette, France from the Lobund Institute, University of Notre-Dame, South Bend, Indiana, U.S.A. Subsequently introduced to Charles River France in 1970 as an axenic colony. Charles River
Proper citation: RRID:RGD_13800555 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12879428
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Embryo (as of 2017-04-19)
Alternate IDs: 12879428
Notes: A double congenic strain bade by introducing segments of chromosome 1, 3, and 4 from SHRSP/Izm into WKY/Izm. This strain was established by mating between WKY.SHRSP-(D1Mgh5-D1Arb21)(D3Mgh16-D3Rat144)/Izm(NBRP Rat No:0713)and WKY.SHRSP-(D1Mgh5-D1Arb21) (D4Mgh7-D4Rat68)/IzmCNBRP Rat No:0714). This strain was established and is maintained in Shimane University. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_12879428 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904063
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-16)
Alternate IDs: 12904063
Notes: This ZFN model carries a 588-bp deletion within Abcg2 gene. Homozygous knockouts display total loss of protein via Western blot Horizon Discovery
Proper citation: RRID:RGD_12904063 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800557
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13800557
Notes: This is the wild-type litter mates of the Hsd11b2 F344 mutants created by ZFN system targeting exon 2 of Hsd11b2 gene was injected into the F344/IcoCrl embryos to induce a 123-bp deletion removing the 3' end of exon 2 and the first 16-bp of intron B and create a premature stop coden TAG.
Proper citation: RRID:RGD_13800557 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13432150
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 13432150
Notes: SS.ZUC-Leprfa/Slc rats were generated as the result of an initial mating of a male Zucker rat (Japan SLC) heterozygous for the fa allele of Lepr with a female DahlS/JrSeac rat (Seac, Japan), followed by multiple rounds of backcrossing of the resulting progeny to the SS strain.
Proper citation: RRID:RGD_13432150 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13506919
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 13506919
Notes: Curtiss and Dunning 1920 at Columbia University Institute for Cancer Research, To National Center for Toxicological Research, FDA.
Proper citation: RRID:RGD_13506919 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13204756
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13204756
Notes: CRISPR/Cas9 system was used to introduce a 5-bp deletion in exon 2 of the rat Pappa2 gene of SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi rat embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13204756 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800838
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13800838
Notes: CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of rat Mybphl gene in the FHH/EurMcwi embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13800838 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13432148
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 13432148
Notes: SS.ZUC-Leprfa/Slc rats were generated as the result of an initial mating of a male Zucker rat (Japan SLC) heterozygous for the fa allele of Lepr with a female DahlS/JrSeac rat (Seac, Japan), followed by multiple rounds of backcrossing of the resulting progeny to the SS strain.
Proper citation: RRID:RGD_13432148 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13208540
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Unknown (as of 2024-09-13)
Alternate IDs: 13208540
Notes: Descendants of rats from the Charles River Laboratories (USA),then to Fvet at Buenos Aires University and since 2014 maintained at Bioterio Central of Facultad de Farmacia y Bioquimica de la Universidad de Buenos Aires. Junin 956 Ciudad Autonoma de Buenos Aires, Argentina Bioterio Central of Facultad de Farmacia y Bioquimica de la Universidad de Buenos Aires. Junin 956 Ciudad Autonoma de Buenos Aires, Argentina
Proper citation: RRID:RGD_13208540 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13782164
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2018-08-24)
Alternate IDs: 13782164
Notes: This model contains a deletion of the endogenous rat SNCA gene, encoding the alpha-synuclein protein. This model was generated using the CRISPR/Cas9 genome targeting strategy. Horizon Discovery
Proper citation: RRID:RGD_13782164 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13782163
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2018-08-24)
Alternate IDs: 13782163
Notes: This model contains a knockin of the A53T-mutated SNCA gene deeming the rat SNCA gene non-functional. The knockin contains humanized amino acids for the region spanning amino acids 53-122. The resulting model expresses a humanized A53T alpha-synuclein protein without endogenous rat alpha-synuclein. Horizon Discovery
Proper citation: RRID:RGD_13782163 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904057
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-16)
Alternate IDs: 12904057
Notes: This ZFN model contains biallelic 20 bp deletion within Abcba1 gene. Animals exhibit increased oral bioavailability of P-gp-specific substrates. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery
Proper citation: RRID:RGD_12904057 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800825
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2018-10-18)
Alternate IDs: 13800825
Notes: CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 2 of rat Muc1 gene in the FHH/EurMcwi embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13800825 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904059
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-16)
Alternate IDs: 12904059
Notes: This model carries knockout of Abcb1a and Abcb1b. Horizon Discovery
Proper citation: RRID:RGD_12904059 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13451132
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13451132
Notes: This Brown Norway from Janvier rat strain spontaneously develops progressive focal retinal layer disorganization, loss of photoreceptors, cystic cavitation, and RMG abnormalities associated with early retinal vascular telangiectasia and late stage subretinal neovascularization. This phenotype bears reminiscent of human Macular telangiectasia 2. A deletion insertion mutation in exon 6 of the rat crb1 was identified to be responsible for this retinal phenotype.
Proper citation: RRID:RGD_13451132 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13210774
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 13210774
Notes: This congenic strain contains a region of BN/SsNHsd chromosome 7 transferred to the ACI/SegHsd strain background.
Proper citation: RRID:RGD_13210774 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207488
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13207488
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Chrnb4 gene of LEW/NCrl rat embryos. The resulting mutation is a 4-bp deletion of exon 4 in the Chrnb4 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207488 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12903272
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2017-05-10)
Alternate IDs: 12903272
Notes: This model contains three knockout genes, the 20-bp deletion within rat Nr1i2, the ZFN-induced 10-bp deletion within rat Nr1i3 gene and the 760-bp deletion in the rat Ahr gene. Horizon Discovery
Proper citation: RRID:RGD_12903272 Copy
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