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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12910940
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 12910940
Notes: The multiple endocrine neoplasia (MEN)-like phenotype was initially identified in a Sprague Dawley rat-breeding colony and subsequently maintained by matings between affected and nonaffected littermates. Because cataracts are the first visible sign of the phenotype it was provisionally designated as "Sprague Dawley white eye." The abbreviation SDwe is used to denote animals expressing the mutant phenotype.
Proper citation: RRID:RGD_12910940 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13432199
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 13432199
Notes: Congenic sub-strains were generated by backcrossing male SHRSP.WKY-(D3Mgh16-D3Rat114)/Gcrc rats to SHRSP females. Progeny generated from this backcross were heterozygous throughout the original congenic interval. Brother X sister mating was carried out to generate sub-strains containing smaller congenic intervals.
Proper citation: RRID:RGD_13432199 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12792954
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12792954
Notes: SS/JrHsdMcwi were crossed with SS.BN-(D13Rat151-D13Rat197)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_12792954 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207494
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13207494
Notes: CRISPR/Cas9 system was used to introduce a 22-bp deletion of exon 2 in the rat Cd55 gene of Crl:SD embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207494 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13208584
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Live Animals (as of 2017-08-14)
Alternate IDs: 13208584
Notes: Transgenic overexpressing Wisp2 under the control of the Ubiqutin C promoter Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13208584 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904893
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2017-05-24)
Alternate IDs: 12904893
Notes: This ZFN model carries the knockout of the rat Slc22a8. Horizon Discovery
Proper citation: RRID:RGD_12904893 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207537
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Live Animals (as of 2017-08-04)
Alternate IDs: 13207537
Notes: Transgenic rat overexpressing Cre under the control of the Cdh5 (VECadherin) promoter. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207537 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13204788
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals; Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13204788
Notes: CRISPR/Cas9 system was used to introduce a 60-bp deletion in exon 2 of the rat Pappa2 gene of SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi rat embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13204788 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207563
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Live Animals (as of 2017-08-04)
Alternate IDs: 13207563
Notes: Transgenic overexpressing tamoxifen inducible CreERT2 under the control of the Mylpf (also known ad Mlc2) promoter Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207563 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13513909
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 13513909
Notes: This is a littermate wild type control strain for SD-Tg(Ren2)27 (RGD:629501), which was generated by the mouse Ren2 renin gene along with its 5' and 3' flanking sequences being microinjected into fertilized eggs from a Hannover Sprague-Dawley (SD) background.
Proper citation: RRID:RGD_13513909 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13782371
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13782371
Notes: A naturally-occurring mutation in Cacna1f was identified in a male Sprague Dawley rat with the phenotype of congenital stationary night blindness.Sequence analysis revealed a point mutation of C to T at position 2941, which changes codon 981 from arginine (CGA) to a stop codon (TGA). This R981Stop point mutation was predicted to lead to a version of protein shortened by a total of 999 amino acids, and missing the C-terminal and, in particular, part of the third and all of the fourth ion transport domains.
Proper citation: RRID:RGD_13782371 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904684
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-17)
Alternate IDs: 12904684
Notes: This model contains two knockout genes, the 20-bp deletion within rat Abcba1 and the 588-bp deletion within rat Abcg2 gene. Horizon Discovery
Proper citation: RRID:RGD_12904684 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13208537
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Live Animals (as of 2017-08-11)
Alternate IDs: 13208537
Notes: Descendants of rats from the Wistar Institute, Philadelphia, Pennsylvania then to Harlan (Indianapolis).Since 1995 maintained at Bioterio Central- Facultad de Farmacia y Bioquÿ¿mica de la Universidad de Buenos Aires. Contact: Junin 956 8 piso Ciudad Autÿ¿noma de Buenos Aires, Argentina Tel/Fax: +54 11 5287 4811 Mail: [email protected] Bioterio Central - FFyB - Universidad de Bs As
Proper citation: RRID:RGD_13208537 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904685
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-17)
Alternate IDs: 12904685
Notes: This ZFN model contains a biallelic 726 bp deletion within the Abcc2 gene. Animals exhibit decreased transport of endogenous glutathione and hyperbilirubinemia. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery
Proper citation: RRID:RGD_12904685 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12880037
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 12880037
Notes: This mutant strain was generated by injecting TALEN targeting exon23 of rat Dmd into Crl:SD embryo. The resulting mutant is a 11 bp-deletion in exon 23 leading to a +1 grame shift and premature stop codon 81 bp after the mutation.
Proper citation: RRID:RGD_12880037 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12880021
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-01)
Alternate IDs: 12880021
Notes: The mutant rat strain was produced by injecting zinc endonuclease targeting the exon 3 of rat Apoe into Sprague Dawley embryos. This mutant rat has a 16-bp deletion in the gene and resulted in complete loss of Apoe protein in homozygotes. Horizon Discovery
Proper citation: RRID:RGD_12880021 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904679
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 12904679
Notes: ZFN system was used to introduce a 25-bp deletion mutation in the exon 4 of Cyp2j4 gene of WKY/NCrl rat embryos. This deletion results in premature stop of protein translation.
Proper citation: RRID:RGD_12904679 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13702084
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 13702084
Notes: To generated Gimap5 congenic BBDP/WorSunn rats, the laboratory introgressed the wild-type Gimap5 locus derived from BBDR (BBDR/Wor) rats (Biomedical Research Models) into BBDP/WorSunn rats. Briefly, BBDP/WorSunn and BBDR/Wor rats were crossed, and the resulting F1 animals were backcrossed to BBDP/WorSunn rats. This step was followed by 10 more, marker- assisted backcrosses of Gimap5 heterozygous progeny to BBDP/WorSunn rats. After the eleventh backcross, nonlymphopenic rats were intercrossed, and their progeny homozygous for wild-type Gimap5 were selected for establishing the congenic non-lymphopenic BBDP/WorSunn line (also called BBDP/WorSunn.BBDR-Iddm2).
Proper citation: RRID:RGD_13702084 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800556
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13800556
Notes: The ZFN system targeting exon 2 of Hsd11b2 gene was injected into the F344/IcoCrl embryos to induce a 123-bp deletion removing the 3' end of exon 2 and the first 16-bp of intron B and create a premature stop coden TAG.
Proper citation: RRID:RGD_13800556 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12910505
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 12910505
Notes: TALEN mediated 607 bp deletion that includes exon 2 of the Mmp12 gene, resulting in a frameshift and premature stop codon
Proper citation: RRID:RGD_12910505 Copy
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