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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12790662
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 12790662
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Mb gene of WKY/NCrl rat embryos. The resulting mutation is a 25-bp deletion in the exon 2 of the Mb gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_12790662 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12790944
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 12790944
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sik2 gene of WKY/NCrl rat embryos. The resulting mutation is a 5-bp deletion in exon 4 of the Sik2 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_12790944 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12879431
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Live Animals (as of 2021-04-22)
Alternate IDs: 12879431
Notes: This strain is a rat strain originating from the Wistar Institute in Philadelphia (USA). The Wistar Institute was named as a memorial to the famous anatomist Professor Casper Wistar at the University of Pennsylvania. CLEA Japan, Inc. started the production and supply of this strain after it was introduced from Carworth (UK). CLEA Japan, Inc
Proper citation: RRID:RGD_12879431 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207551
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Live Animals (as of 2017-08-04)
Alternate IDs: 13207551
Notes: Transgenic rat overexpressing tamoxifen inducible Cre/ERT2 under the control of the Nphs2 (Podocin) promoter Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207551 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12879437
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals (as of 2017-04-19)
Alternate IDs: 12879437
Notes: This strain (Nephropathy model) was segrigated from SD strain (CLEA Japan,Inc.) by selective mating on the basis of total cholesterol level in blood. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_12879437 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13524998
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 13524998
Notes: In 1989, a femal sprague-Dawley rat with spontaneous cataracts was observed in the Upjohn Pharmaceuticals Limited Tsukuba Research Laboratory colony. The cataract was demonstrated to be hereditary and it was determined that there are two cataract types with different onset ages.
Proper citation: RRID:RGD_13524998 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12792947
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12792947
Notes: SS/JrHsdMcwi were crossed with SS.BN-(D13Rat151-D13Rat197)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_12792947 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12792949
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12792949
Notes: SS/JrHsdMcwi were crossed with SS.BN-(D13Rat151-D13Rat197)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_12792949 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12792946
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12792946
Notes: SS/JrHsdMcwi were crossed with SS.BN-(D13Rat151-D13Rat197)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_12792946 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13628730
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13628730
Notes: TALEN targeting the 2nd exon of rat Il2rg gene was designed and mRNA coding these TALEN was microinjected into Crl:SD embyo.This strain carrying an 80 bp deletion generated a premature stop codon in the 3rd exon. No Il2rg protein was detected by western blot.
Proper citation: RRID:RGD_13628730 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12880026
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2017-05-01)
Alternate IDs: 12880026
Notes: This rat model carries a bi-allelic deletion of the amyloid precursor protein (APP) gene. Horizon Discovery
Proper citation: RRID:RGD_12880026 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13452407
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 13452407
Notes: These animals were bought from Harlan Indianapolis, Indiana U.S.A. and maintained at the University of Akron breeding colonies, Akron, Ohio.
Proper citation: RRID:RGD_13452407 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13452406
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 13452406
Notes: SHR strain obtained from Harlan Sprague-Dawley (Indianapolis, IN) and maintained at the University of Akron breeding colonies, Akron, Ohio
Proper citation: RRID:RGD_13452406 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207509
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm; Cryorecovery (as of 2021-11-03)
Alternate IDs: 13207509
Notes: CRISPR/Cas9 system was used to introduce a mutation in the P2rx1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 7-bp deletion in Exon 2 of the P2rx1 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207509 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12903251
Source Database: Rat Genome Database (RGD)
Genetic Background: consomic
Availability: Unknown
Alternate IDs: 12903251
Notes: Chr 17 from LN was introgressed onto the genetic background of LH by crossing LH/MRrrcAek male to LN/MRrrcAek female rats.
Proper citation: RRID:RGD_12903251 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12905036
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-31)
Alternate IDs: 12905036
Notes: This model expresses cre-recombinase under the control of the endogenous 5 prime-hydroxytryptamine receptor 3A (5Ht3a) promoter enabling specific expression in 5Ht3a positive serotonergic neurons. This model possesses a targeted insertion of (T2A)-cre immediately before the translational stop in the open reading frame of the 5Ht3a gene. The 5Ht3a-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines. Horizon Discovery
Proper citation: RRID:RGD_12905036 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904903
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-24)
Alternate IDs: 12904903
Notes: This ZFN model carries a 2 bp deletion within exon 3 of the Rag2 gene on chromosome 3. Homozygous Rag2 knockout rats display loss of RAG2 protein via Western blot. Homozygous Rag2 knockout rats show loss of B and T cells by FACS analysis. Horizon Discovery
Proper citation: RRID:RGD_12904903 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904902
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2017-05-24)
Alternate IDs: 12904902
Notes: This ZFN model carries a 29 bp deletion within exon 2 of the Rag1 gene on chromosome 3. Rag1 knockout rats lack mature B and T lymphocytes. Horizon Discovery
Proper citation: RRID:RGD_12904902 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11553908
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 11553908
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Trpc6 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 3-bp substitutions to generate P112Q in Exon 2 of the Trpc6 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_11553908 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904733
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2017-05-19)
Alternate IDs: 12904733
Notes: This ZFN induced knockout model contains 11 bp bi-allelic deletion within exon 1 of the Slc22a1. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery
Proper citation: RRID:RGD_12904733 Copy
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