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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11553848
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: 11553848
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Trpv4 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 5-bp deletion in Exon 4 of the Trpv4 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_11553848 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11532753
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 11532753
Notes: The F344.ZUC,OLETF double congenic was produced by crossing F344.ZUC-Leprfa with F344.OLETF-( D5Rat166-D5Rat90) and then selecting Leprfa -Niddm24 (fa/fa-Nidd6/of) homozygotes National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11532753 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12738394
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12738394
Notes: The BDIX.BDIV-D6Mit8-D6Rat229/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background.
Proper citation: RRID:RGD_12738394 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11561897
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 11561897
Notes: The CRISPR/Cas9 genome editing system was used to generate this knockout mutant rat strain. It created a 618-bp deletion in rat Lrap gene. The recipient zygotes were the Wistar rats from Charles River.
Proper citation: RRID:RGD_11561897 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12437069
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 12437069
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Btg2 gene of SS.BN-(D13Rat25-rs198199323)/Mcwi rat embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_12437069 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12792945
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12792945
Notes: SS/JrHsdMcwi were crossed with SS.BN-(D13Rat151-D13Rat197)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_12792945 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12790608
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 12790608
Notes: The CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 2 of the Cd14 gene of SS/JrHsdMcwi rat embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_12790608 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11553912
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 11553912
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Trpc6 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 2-bp insertion in Exon 2 of the Trpc6 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_11553912 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11553877
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct (as of 2017-07-18)
Alternate IDs: 11553877
Notes: CRISPR/Cas9 system was used to introduce a mutation in the P2rx1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 24-bp deletion in Exon 1 of the P2rx1 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_11553877 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12879423
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 12879423
Notes: This transgenic rat strain was established by Dr. Yamanaka (Nagoya University) in 2012. Background strain: Wistar rat (CLEA Japan). plasmid backbone: pCR2.1. Transgene: human HCRT gene promoter, cre recombinase, EGFP gene, 2A gene. EGFP and cre recombinase are specifically expressed in orexin neurons. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_12879423 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11554329
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Live Animals (as of 2016-10-26)
Alternate IDs: 11554329
Notes: The BDIX.BDIV-D10Got1-D10Rat45/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background.
Proper citation: RRID:RGD_11554329 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12879424
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-04-19)
Alternate IDs: 12879424
Notes: This strain was established at Kyoto University. ChR90/EGFP fusion gene sequence under CAG promoter is knock-in at the ROSA26 locus. Background strain: Long-Evans strain (charles river). COP4*: Stigeoclonium helveticum-derived channelrhodopsin (Chronos, ChR90). ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_12879424 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11554327
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Live Animals (as of 2016-10-26)
Alternate IDs: 11554327
Notes: The BDIX.BDIV-D10Mit3-D10Mgh16/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background.
Proper citation: RRID:RGD_11554327 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12879426
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Embryo (as of 2017-04-19)
Alternate IDs: 12879426
Notes: This congenic strain was established by introducing a segment of chromosome14 (D14Got74-D14Rat132 including Smek2 gene) from Brown Norway(BN)/seac strain into ExHC/Seac strain. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_12879426 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12738388
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12738388
Notes: The BDIX.BDIV-D6Rat132-D6Mgh3/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background.
Proper citation: RRID:RGD_12738388 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12790698
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 12790698
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Pon1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion of exon 5 in the Pon1 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_12790698 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11561905
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2016-11-10)
Alternate IDs: 11561905
Notes: Transposed "Bhr2" was inserted into intron 4 of Gabrb1 gene by piggyBac (pb) transposon system. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11561905 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11565829
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown (as of 2016-11-28)
Alternate IDs: 11565829
Notes: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting rat Ttn into F344 embryos. The zinc-finger nuclease mediated genome editing system created a deletion of exons 2-6 (5,286-bp deletion, coordinates 2,323-7,608) to introduce a frameshift (Rnor_5.0). Duke-National University of Singapore, Singapore
Proper citation: RRID:RGD_11565829 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11568700
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals; Cryopreserved Embryo (as of 2016-12-13)
Alternate IDs: 11568700
Notes: The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Nlgn3 into Sprague Dawley embryos. Homozygous knockout rats exhibit complete loss of target protein as demonstrated by Western blot. Horizon Discovery
Proper citation: RRID:RGD_11568700 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11564343
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2016-11-16)
Alternate IDs: 11564343
Notes: Background strain: Long-Evans (Institute for Animal Reproduction); pRSET-B tdTomato is provided by Dr. Roger Tsien (UCSD); Transgene: CAG promoter (CMV virus, chicken), tdTomato (Discosoma sp.); BAC clone: mouse ROSA26 BAC (RP23-244D9) National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11564343 Copy
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