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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12904059
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-16)
Alternate IDs: 12904059
Notes: This model carries knockout of Abcb1a and Abcb1b. Horizon Discovery
Proper citation: RRID:RGD_12904059 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13451132
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13451132
Notes: This Brown Norway from Janvier rat strain spontaneously develops progressive focal retinal layer disorganization, loss of photoreceptors, cystic cavitation, and RMG abnormalities associated with early retinal vascular telangiectasia and late stage subretinal neovascularization. This phenotype bears reminiscent of human Macular telangiectasia 2. A deletion insertion mutation in exon 6 of the rat crb1 was identified to be responsible for this retinal phenotype.
Proper citation: RRID:RGD_13451132 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13210774
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 13210774
Notes: This congenic strain contains a region of BN/SsNHsd chromosome 7 transferred to the ACI/SegHsd strain background.
Proper citation: RRID:RGD_13210774 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13207488
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13207488
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Chrnb4 gene of LEW/NCrl rat embryos. The resulting mutation is a 4-bp deletion of exon 4 in the Chrnb4 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13207488 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12903272
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2017-05-10)
Alternate IDs: 12903272
Notes: This model contains three knockout genes, the 20-bp deletion within rat Nr1i2, the ZFN-induced 10-bp deletion within rat Nr1i3 gene and the 760-bp deletion in the rat Ahr gene. Horizon Discovery
Proper citation: RRID:RGD_12903272 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792825
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 13792825
Notes: The Sleeping Beauty transposon system was used to introduce a Mfn1-GFP fusion driven by a ubiquitous promoter, interupted by a floxed stop cassette. This is line A. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13792825 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13800810
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-10-18)
Alternate IDs: 13800810
Notes: CRISPR/Cas9 system and the single-stranded oligodeoxynucleotide (ssODN ) were combined to introduce the R231H mutation in the Kcnq1 gene of SS/JrHsdMcwi rat embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13800810 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792705
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13792705
Notes: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created ( SD-Trpv1em1Sage-/-). This wild type mutant is the wild type offspring from the cross of heterozygous mutants.
Proper citation: RRID:RGD_13792705 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792827
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2018-10-02)
Alternate IDs: 13792827
Notes: The Sleeping Beauty transposon system was used to introduce a cre-ERT2 fusion, driven by the UbC promoter. This is line D.Cre activity is detected even without tamoxifen induction. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13792827 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792828
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2018-10-02)
Alternate IDs: 13792828
Notes: The Sleeping Beauty transposon system was used to introduce a cre-ERT2 fusion, driven by the UbC promoter. This is line E.Cre activity is detected even without tamoxifen induction. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13792828 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792821
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 13792821
Notes: The Sleeping Beauty transposon system was used to introduce a Drp1-GFP fusion driven by a ubiquitous promoter, interupted by a floxed stop cassette. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13792821 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792701
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2018-09-21)
Alternate IDs: 13792701
Notes: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created. Homozygous knockout rats exhibit complete loss of Trpv1 protein. Horizon Discovery
Proper citation: RRID:RGD_13792701 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13703119
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13703119
Notes: This strain was produced by injecting TALEN targeting exon 2 of rat Lamp2 into SD embryos. The resulting mutation is a 2-bp deletion and results in knockout of Lamp2 protein in Lamp2 y/- male.
Proper citation: RRID:RGD_13703119 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12903270
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals (as of 2017-05-10)
Alternate IDs: 12903270
Notes: This model contains two knockout genes, the 20-bp deletion within rat Nr1i2 and the ZFN-induced 10-bp deletion within rat Nr1i3 gene. Horizon Discovery
Proper citation: RRID:RGD_12903270 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13464327
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Sperm (as of 2018-01-03)
Alternate IDs: 13464327
Notes: When the depositor (The Institute of Environmental Toxicology ) conducted mating experiment using male Crl:CD(SD) rats, the offsprings of backcrossed-generation showed multiple malformations such as ectrodactylism, cleft palate or lip in 2013. These phenotype might be inherited in an autosomal recessive pattern. Therefore the congenic strain was established using WKY strain as the recipient strain. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_13464327 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792813
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2018-10-01)
Alternate IDs: 13792813
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SHRSP/A3NCrl rat embryos. The resulting mutation is a 11-bp deletion in Exon 3 of the Spp1 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13792813 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13464329
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo (as of 2023-09-28)
Synonyms: , FPL
Alternate IDs: 13464329
Notes: This spontaneous mutant strain wa found in a colony of Jcl:Wistar strain at the Institute of Environmental Toxicology in 1978: 3 rats out of 13 rats showed fused right pulmonary lobes with reduction deformity of middle pulmonary lobes. These rats also had the syndactylism or paten tof the eyelid. It was difficult to maintain this strain in homozygous condition, mating system has been changed to sib mating between heterozygous rats. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_13464329 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13208231
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 13208231
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of WKY/NCrl rat embryos. The resulting mutation is a 1-bp insertion in the exon 4 of the Tph1 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13208231 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13793372
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 13793372
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Tlr4 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp deletion in exon 2. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13793372 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13799350
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2018-10-10)
Alternate IDs: 13799350
Notes: CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of F2r gene in the T2DN/Mcwi embryos. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_13799350 Copy
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