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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11041108
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm
Alternate IDs: 11041108
Notes: The Laboratory of Reproductive Toxicology at the Institute of Environmental Toxicology has been maintaining a Wistar derived PD strain of rats. In 1986, 1 female and 2 males exhibiting very short and sparse vibrissae were found in a litter of 7 parented by a pd/pd female and phenotypically normal pd/+ male. In 2008, a male Wistar rat and F56 female were crossed, and obtained heterozygous rats were sib-mated. After that, sib mating between homozygous rats was started. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11041108 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11041106
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 11041106
Notes: background strain #65306; Long-Evans rat #65288; Iar:Long-Evans #65289; Transgene #65306; (1) Parvalbumin (PV) promoter #65306; mouse derived (MGI:97821). PV is calcium-binding protein. (2) tetracycline transactivator (tTA) #65306; Fusion protein of tetracycline repressor (Escherichia coli-derived) and VP16 (Herpes simplex virus-derived). In the absence of Doxycycline (Dox), tTA binds to tetracycline-responsive element (TRE) and expression of TRE-controlled genes can be induced. Vector #65306; pBlueScript (Stratagene), pBACe3.6 (CHORI) National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11041106 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040922
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 11040922
Notes: CHORI230-9K13 recombinant BAC (Mrs2-EGFP) was introduced into Crlj:Wistar embyos. BAC Tg rats were backcrossed with WTC.DMY-dmy. dmy gene: homozygous, transgene: hemizygous. 4 lines: #15, #39, #92, #131 National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11040922 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040527
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 11040527
Notes: ZFN mutant founders were backcrossed with SHR/NCrl to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Proper citation: RRID:RGD_11040527 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040920
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 11040920
Notes: CHORI230-9K13 recombinant BAC (Mrs2/EGFP) was introduced into Crlj:Wistar embyos. BAC Tg rats were backcrossed with WTC.DMY-dmy. dmy gene: homozygous, transgene: hemizygous. 4 lines: #15, #39, #92, #131 National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11040920 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040525
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 11040525
Notes: ZFN mutant founders were backcrossed with SHR/NCrl to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders.
Proper citation: RRID:RGD_11040525 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10401835
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 10401835
Notes: A congenic strain made by introducing a 15 Mbp segment of chromosome 17 from F344/NHsd into WKY/Cruk, this region has the distal end of Cm15 QTL
Proper citation: RRID:RGD_10401835 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11553899
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 11553899
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Trpv2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 17-bp deletion in Exon 4 of the Trpv2 gene. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_11553899 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10401837
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 10401837
Notes: A congenic substrain derived from the progenitor strain WKY.F344-(D17Got91-D17Rat51)/Tja
Proper citation: RRID:RGD_10401837 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040950
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-07-12)
Alternate IDs: 11040950
Notes: This strain was established by Zinc-finger nucleases (ZFNs) method causing 20-bp deletion in the exon1 of Prkdc gene and a 653-bp deletion Il2rg gene. Background strain: TM/Kyo National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11040950 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10395233
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Unknown
Alternate IDs: 10395233
Notes: Received Sprague-Dawley derived breeding stock from Charles River Laboratory in 1958 and crossed with Sprague-Dawley rats received from ARS/Sprague-Dawley in 1975. Caesarean rederived in 1997. Simonsen Laboratories
Proper citation: RRID:RGD_10395233 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040957
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm
Alternate IDs: 11040957
Notes: This strain was established by ENU mutagenesis (gene-driven) using F344/NSlc and has a missense mutation（R271C). National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11040957 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11354901
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 11354901
Notes: This is a congenic substrain developed by crossing SS.SHR-(D9Rat7-D9Rat84)/Mco to SS/Jr and the F1 were intercrossed to produce an F2 population,which was genotyped using microsatellite markers. The selected recombinant rats were crossed to SS/Jr again to duplicate the recombinant region.
Proper citation: RRID:RGD_11354901 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10402819
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Live Animals; Cryopreserved Sperm (as of 2021-11-03)
Alternate IDs: 10402819
Notes: This strain was produced by injecting ZFNs targeting the sequence CATGGCTCCGACCCCctctacACCCCGGAACCG into DA/OlaHsd rat embryos. The resulting mutation is a 10-bp frameshift deletion in exon 7.
Proper citation: RRID:RGD_10402819 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10401845
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 10401845
Notes: ZFN mutant founders were backcrossed with WKY/Cruk to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. The resulting mutation 77 has a stop codon, 15 amino acids from the ZFN-binding site, that resulted in a 490 amino acids (54 kDa) truncated protein, 198 amino acids smaller than the WT protein.
Proper citation: RRID:RGD_10401845 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10395226
Source Database: Rat Genome Database (RGD)
Genetic Background: outbred
Availability: Unknown
Alternate IDs: 10395226
Notes: Received from Dr. Evans, University of California, Berkeley - Experimental Institute of Biology in 1949. Caesarean rederived in 1997. Selection is based on the black-hooded phenotype. Simonsen Laboratories
Proper citation: RRID:RGD_10395226 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=12792226
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 12792226
Notes: SS/JrHsdMcwi were crossed with SS.BN-(D13Rat151-D13Rat197)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_12792226 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10401841
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 10401841
Notes: A congenic substrain derived from the progenitor strain WKY.F344-(D17Got91-D17Rat51)/Tja
Proper citation: RRID:RGD_10401841 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11040946
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Sperm (as of 2017-06-08)
Alternate IDs: 11040946
Notes: This strain was established by Zinc-finger nucleases (ZFNs) method taregting exon1 of rat Prkdc gene, resulting a 46-deletion. Background strain: F344/Stm National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_11040946 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10054473
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 10054473
Notes: SS/JrHsdMcwi were crossed with SS-13BN/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain
Proper citation: RRID:RGD_10054473 Copy
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