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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521661
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_150521661, 150521661, RRRC_928, RRRC_0928, RRRC_00928
Notes: The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. Expresses mCherry in cells of the brain transduced with a Cre-expression virus. Currently in SD background generated by backcrossing to LE-Tg(DIO-mCherry)2Ottc Rat Resource and Research Center
Proper citation: RRID:RRRC_00928 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=626168255
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryorecovery (as of 2025-10-30)
Alternate IDs: RGD_626168255, 626168255, RRRC_974, RRRC_0974, RRRC_00974
Notes: This novel transgenic rat produces low levels of human familial cerebral amyloid angiopath (CAA) Dutch/Iowa E22Q/D23N mutant amyloid beta protein in brain and recapitulates many of the pathologic aspects of human small-vessel CAA. A pcDNA3 vector containing 2.1 kb of human APP (isoform 770) cDNA was used to introduce the mutations Swedish K670N/M671L, Dutch E693Q, and Iowa D694N using the QuikChange kit. The APP770-SwDI cDNA was amplified by PCR using primers containing the NheI five linker and SacII three linker. The PCR product of the APP770-SwDI was subcloned between exons II and IV of a Thy1.2 expression cassette using NheI and SacII restriction sites. The completed construct was microinjected into pronuclei of Sprague-Dawley single-cell embryos. Founder rats were identified by Southern blot analysis of tail DNA. Transgenic offspring were determined by PCR analysis of tail DNA. All subsequent analyses were performed with hemizygous transgenic rats. Rat Resource and Research Center
Proper citation: RRID:RRRC_00974 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14390082
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14390082, 14390082, RRRC_865, RRRC_0865, RRRC_00865
Notes: The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Rats were rederived from frozen embryos in 2002 and bred onto SD background for >35 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center
Proper citation: RRID:RRRC_00865 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588559
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm; Cryorecovery
Alternate IDs: RGD_9588559, 9588559, RRRC_747, RRRC_0747, RRRC_00747
Notes: The transgene contains Cre recombinase reporter rat expressing the red fluorescent protein gene (iRFP) driven by the EF1 alpha promoter. Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00747 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629006611
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo (as of 2025-11-06)
Alternate IDs: RGD_629006611, 629006611, RRRC_1012, RRRC_01012
Notes: Genetic Alteration(s):human ACE2 gene under expression of the human ACE2 promoter. Eight copies of the transgene are randomly integrated into an as yet unknown insertion site. Deposited at Rat Resource and Research Center
Proper citation: RRID:RRRC_01012 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566458
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-07-01)
Alternate IDs: RGD_1566458, 1566458, RRRC_48, RRRC_048, RRRC_0048, RRRC_00048
Notes: F344 embryos were microinjected with R26-hPAP trangene which comprises of 0.8 kb genomic sequence of ROSA 26 promoter fused to human placental alkaline phosphatase (hPAP, ALPP). Rat Resource and Research Center
Proper citation: RRID:RRRC_00048 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=737703
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-07-08)
Alternate IDs: RGD_737703, 737703, RRRC_42, RRRC_042, RRRC_0042, RRRC_00042
Notes: Lewis from CRL were used as the background strain. This strain was made by pronuclear injection into Lewis embryos. The embryos were coinjected with DNA fragments containing the HLA-B*0702 human gene and the human beta-2-microglobulin gene. Founder 120-4 was selected and carrier animals from this founder were mated and this strain was bred to homozygosity. Rat Resource and Research Center
Proper citation: RRID:RRRC_00042 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1300439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-07-10)
Alternate IDs: RGD_1300439, 1300439, RRRC_65, RRRC_065, RRRC_0065, RRRC_00065
Notes: This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into SD rat embryos. Animals that exhibited fluorescence of tails where then mated. The colony was transferred from Carlos Lois, California Institute of Technology, Pasedena, California to the Rat Resource and Research Center in 2002. This strain has been maintained by backcrossing carrier males to SD stock females in order to segregate transgenes and maintain the SD background. The strain now carries a single transgene which is located at chromosome 14q21. Rat Resource and Research Center
Proper citation: RRID:RRRC_00065 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6478791
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6478791, 6478791, RRRC_307, RRRC_0307, RRRC_00307
Notes: This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into Lewis rat embryos. Animals that exhibited fluorescence of tails were mated. Offspring were bred with Lewis wild-type mates to map transgene location. Animals were backcrossed 10 generations onto F344. Rat Resource and Research Center
Proper citation: RRID:RRRC_00307 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2304211
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo (as of 2018-07-16)
Alternate IDs: RGD_2304211, 2304211, RRRC_301, RRRC_0301, RRRC_00301
Notes: This strain expresses the cre recombinase ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscles established at Jichi Medical School. National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Proper citation: RRID:RRRC_00301 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247278
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-18)
Alternate IDs: RGD_7247278, 7247278, RRRC_655, RRRC_0655, RRRC_00655
Notes: Camk2a-tTA transgenic rats expressing tTA under regulatory control of the forebrain promotor Camk2a. Transgene expression can be blocked by administration of doxycycline to drinking water. Rat Resource and Research Center
Proper citation: RRID:RRRC_00655 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247289
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-18)
Alternate IDs: RGD_7247289, 7247289, RRRC_650, RRRC_0650, RRRC_00650
Notes: SD embryos were microinjected with a DNA construct containing the GFP gene downstream of a miniCMV promoter under the control of tetracycline response element (TRE). The pLV-Tet-GFP was generated by co-transfection of pLV-Tet-GFP, pÎ8.9 and pVSV-G into a 293FT packaging cell line Rat Resource and Research Center
Proper citation: RRID:RRRC_00650 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247290
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-08-22)
Alternate IDs: RGD_7247290, 7247290, RRRC_627, RRRC_0627, RRRC_00627
Notes: SD embryos were microinjected with a lentiviral construct containing the rat P2ry2 gene (G protein-coupled purinergic receptor P2Y2) under control of an ubiquitin-C promoter. Results in over-expression of P2ry2 mRNA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00627 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2304311
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo (as of 2017-08-08)
Alternate IDs: RGD_2304311, 2304311, RRRC_298, RRRC_0298, RRRC_00298
Notes: This strain expresses LacZ ubiquitously driven by the gene trap ROSA26 promoter established at Jichi Medical School. National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Proper citation: RRID:RRRC_00298 Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15398
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Col1a1|cre|
Source References: PMID: 15470637, PMID: 16533949, PMID: 15653467
Alternate IDs: MMRRC_15398-UCD, MMRRC_015398, MMRRC_15398
Notes: Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_015398-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15495
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: EGFP|Tac2|
Source References: PMID: 14586460
Alternate IDs: MMRRC_15495-UCD, MMRRC_015495, MMRRC_15495
Notes: Research areas: Cell Biology, Developmental Biology, Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: GENSAT
Proper citation: RRID:MMRRC_015495-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15493
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: EGFP|Mtap|
Source References: PMID: 14586460
Alternate IDs: MMRRC_15493-UCD, MMRRC_015493, MMRRC_15493
Notes: Research areas: Cell Biology, Developmental Biology, Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: GENSAT
Proper citation: RRID:MMRRC_015493-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15424
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: EGFP|Sirt2|
Source References: PMID: 14586460
Alternate IDs: MMRRC_15424-UCD, MMRRC_015424, MMRRC_15424
Notes: Research areas: Cell Biology, Developmental Biology, Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: GENSAT
Proper citation: RRID:MMRRC_015424-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15490
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Gng3|EGFP|
Source References: PMID: 14586460
Alternate IDs: MMRRC_15490-UCD, MMRRC_015490, MMRRC_1549
Notes: Research areas: Cell Biology, Developmental Biology, Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: GENSAT
Proper citation: RRID:MMRRC_015490-UCD Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15422
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: EGFP|Magea8|
Source References: PMID: 14586460
Alternate IDs: MMRRC_15422-UCD, MMRRC_015422, MMRRC_15422
Notes: Research areas: Cell Biology, Developmental Biology, Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: GENSAT
Proper citation: RRID:MMRRC_015422-UCD Copy
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