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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=126781844
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2024-01-04)
Alternate IDs: RGD_126781844, 126781844, RRRC_878, RRRC_0878, RRRC_00878
Notes: This mutant strain was created by injecting embryos from 'docking site ready (DSR)' rat strains. The DSR rat strain, or TARGAT /TM rat strain was generated using CRISPR/Cas9. The DSR embryos were microinjected with integrase, a mixture of TARGATT Cre DNA constructs containing rabbit smooth muscle myosin heavy chain (SMHC) gene promoter, and a fluorescent reporter mCherry in the Cre cassette linked by a T2A sequence. The vascular smooth muscle tissue-specific expression of a CreERT2 is tamoxifen-dependent." Rat Resource and Research Center
Proper citation: RRID:RRRC_00878 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695547
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2019-07-08)
Alternate IDs: RGD_14695547, 14695547, RRRC_624, RRRC_0624, RRRC_00624
Notes: This strain was made by pronuclear injection into LEW/Crl embryos. The embryos were co-injected with DNA fragments containing the HLA-B*2705 human gene and the human beta-2-microglobulin gene. The strain carries 55 copies of HLA-B*2705 and 29 copies of human beta-2-microglobulin gene. The transgenic strain was transferred from Dr. Joel Taurog, University of Texas Southwestern Medical School in Dallas to the Rat Resource and Research Center . Rat Resource and Research Center
Proper citation: RRID:RRRC_00624 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695548
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2019-07-08)
Alternate IDs: RGD_14695548, 14695548, RRRC_622, RRRC_0622, RRRC_00622
Notes: This strain was made by pronuclear injection into LEW/Crl embryos. The embryos were co-injected with DNA fragments containing the HLA-B*2705 human gene and the human beta-2-microglobulin gene. The strain carries 150 copies of HLA-B*2705 and 90 copies of human beta-2-microglobulin gene. The transgenic strain was transferred from Dr. Joel Taurog, University of Texas Southwestern Medical School in Dallas to the Rat Resource and Research Center . Rat Resource and Research Center
Proper citation: RRID:RRRC_00622 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10412325
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2019-03-18)
Alternate IDs: RGD_10412325, 10412325, RRRC_767, RRRC_0767, RRRC_00767
Notes: The transgene expresses BAC transgenic using rat dopamine receptor 1 promoter to express Cre recombinase in D1R neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00767 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10412327
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2019-03-18)
Alternate IDs: RGD_10412327, 10412327, RRRC_768, RRRC_0768, RRRC_00768
Notes: The transgene expresses BAC transgenic using rat dopamine receptor 2 promoter to express Cre recombinase in D2R neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00768 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695026
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2021-02-12)
Alternate IDs: RGD_14695026, 14695026, RRRC_852, RRRC_0852, RRRC_00852
Notes: Cre recombinase has been inserted into the genome under the control of the Crh promoter. Generated on Wistar and backcrossed to Wistar every generation. Rat Resource and Research Center
Proper citation: RRID:RRRC_00852 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=53621137
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2024-01-10)
Alternate IDs: RGD_53621137, 53621137, RRRC_868, RRRC_0868, RRRC_00868
Notes: The CRISPR/Cas9 system was injected to the Crl:CD(SD)embryo to induce the knock-in Cre-ERT2 cassette at the 3' end of Wnt1 gene linked by 2A peptide. This model is used to lineage tracing of neural crest cells by tissue specific expression of creERT2 Rat Resource and Research Center
Proper citation: RRID:RRRC_00868 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245494
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-05)
Alternate IDs: RGD_7245494, 7245494, RRRC_633, RRRC_0633, RRRC_00633
Notes: Strain carries a transgene expressing human TDP43 with the M337V mutation under control of a tTA-dependent promoter (TRE). When mated to a second transgenic strain (RRRC:632) that carries a tetracycline-controlled transactivator driven by the mouse choline acetyltransferase (Chat) promoter, the expression of mutant TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center
Proper citation: RRID:RRRC_00633 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245488
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-05)
Alternate IDs: RGD_7245488, 7245488, RRRC_632, RRRC_0632, RRRC_00632
Notes: Rats express a mouse tetracycline-controlled transactivator (tTA) driven by the mouse choline acetyltransferase (Chat) promotor. When mated to a second transgenic strain (RRRC:00633) that carries a target gene (TDP43) under the regulation of a tetracycline response element (TRE), the expression of TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center
Proper citation: RRID:RRRC_00632 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566458
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-07-01)
Alternate IDs: RGD_1566458, 1566458, RRRC_48, RRRC_048, RRRC_0048, RRRC_00048
Notes: F344 embryos were microinjected with R26-hPAP trangene which comprises of 0.8 kb genomic sequence of ROSA 26 promoter fused to human placental alkaline phosphatase (hPAP, ALPP). Rat Resource and Research Center
Proper citation: RRID:RRRC_00048 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=737703
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-07-08)
Alternate IDs: RGD_737703, 737703, RRRC_42, RRRC_042, RRRC_0042, RRRC_00042
Notes: Lewis from CRL were used as the background strain. This strain was made by pronuclear injection into Lewis embryos. The embryos were coinjected with DNA fragments containing the HLA-B*0702 human gene and the human beta-2-microglobulin gene. Founder 120-4 was selected and carrier animals from this founder were mated and this strain was bred to homozygosity. Rat Resource and Research Center
Proper citation: RRID:RRRC_00042 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1300439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-07-10)
Alternate IDs: RGD_1300439, 1300439, RRRC_65, RRRC_065, RRRC_0065, RRRC_00065
Notes: This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into SD rat embryos. Animals that exhibited fluorescence of tails where then mated. The colony was transferred from Carlos Lois, California Institute of Technology, Pasedena, California to the Rat Resource and Research Center in 2002. This strain has been maintained by backcrossing carrier males to SD stock females in order to segregate transgenes and maintain the SD background. The strain now carries a single transgene which is located at chromosome 14q21. Rat Resource and Research Center
Proper citation: RRID:RRRC_00065 Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41198
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Myh6|DMD||Dmd|
Source References: PMID: 6583703
Alternate IDs: MMRRC_41198-JAX, MMRRC_041198, MMRRC_41198
Notes: Research areas: Cardiovascular, Cell Biology, Models for Human Disease; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041198-JAX Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41182
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: TK1|ERE|lacZ|
Source References: PMID: 11606437
Alternate IDs: MMRRC_41182-MU, MMRRC_041182, MMRRC_41182
Notes: Research areas: Cancer, Cell Biology, Developmental Biology, Immunology and Inflammation, Metabolism, Models for Human Disease, Neurobiology, Obesity, Reproduction, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041182-MU Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41180
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: TK1|lacZ|ERE|
Source References: PMID: 11606437
Alternate IDs: MMRRC_41180-MU, MMRRC_041180, MMRRC_4118
Notes: Research areas: Cancer, Cell Biology, Developmental Biology, Immunology and Inflammation, Metabolism, Models for Human Disease, Neurobiology, Obesity, Reproduction, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041180-MU Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41177
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Ckm|Prkaa2|
Source References: PMID: 16186119, PMID: 19403598, PMID: 20622170, PMID: 20701589, PMID: 18728234, PMID: 17709097, PMID: 17513699, PMID: 17452058, PMID: 17287469, PMID: 16804077, PMID: 15811316
Alternate IDs: MMRRC_41177-JAX, MMRRC_041177, MMRRC_41177
Notes: Research areas: Diabetes, Metabolism, Obesity, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041177-JAX Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41410
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Myh6|Pdk4|
Source References: PMID: 18083902, PMID: 21321124
Alternate IDs: MMRRC_41410-MU, MMRRC_041410, MMRRC_4141
Notes: Research areas: Cardiovascular, Diabetes, Metabolism, Models for Human Disease; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041410-MU Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41420
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: |LMP1|
Source References: PMID: 9751773, PMID: 16247482, PMID: 17997602, PMID: 22991431
Alternate IDs: MMRRC_41420-UNC, MMRRC_041420, MMRRC_4142
Notes: Research areas: Cancer, Virology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041420-UNC Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41421
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: |LMP2A|
Source References: PMID: 9768760, PMID: 22991431, PMID: 18579586, PMID: 18559925, PMID: 11489945, PMID: 15361852
Alternate IDs: MMRRC_41421-UNC, MMRRC_041421, MMRRC_41421
Notes: Research areas: Cancer, Virology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041421-UNC Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41502
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: |MYH6|Mb
Alternate IDs: MMRRC_41502-UCD, MMRRC_041502, MMRRC_4152
Notes: Research areas: Cancer, Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Endocrine Deficiency, Hematology, Metabolism, Models for Human Disease, Obesity, Research Tools; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_041502-UCD Copy
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