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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2292532
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_2292532, 2292532, RRRC_277, RRRC_0277, RRRC_00277
Notes: F344 embryos were microinjected with human beta-C-terminal fragment of the amyloid protein Rat Resource and Research Center
Proper citation: RRID:RRRC_00277 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150523775
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm; Cryorecovery (as of 2022-03-10)
Alternate IDs: RGD_150523775, 150523775, RRRC_916, RRRC_0916, RRRC_00916
Notes: This strain was made by pronuclear injection into LEW/Crl embryos. The embryos were co-injected with DNA fragments containing the HLA-B*2705 human gene and the human beta-2-microglobulin gene. The strain carries 20 copies of HLA-B*2705 and 15 copies of the human beta-2-microglobulin gene. Rat Resource and Research Center
Proper citation: RRID:RRRC_00916 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150523778
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm; Cryorecovery (as of 2022-03-10)
Alternate IDs: RGD_150523778, 150523778, RRRC_917, RRRC_0917, RRRC_00917
Notes: This strain carries 35 copies of genomic human B2-microglobulin gene. When crossed with the 21-3 line (RRRC:00 916), the F1 males develop a spontaneous disease mimicking human spondyloarthritis. Rat Resource and Research Center
Proper citation: RRID:RRRC_00917 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588570
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588570, 9588570, RRRC_766, RRRC_0766, RRRC_00766
Notes: The transgene contains reporter rat expressing eGFP in cFos expressing cells Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00766 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2305976
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo
Alternate IDs: RGD_2305976, 2305976, RRRC_339, RRRC_0339, RRRC_00339
Notes: This is the strain expresses human Amyloidogenic transthyretin (ATTR) V30M driven by the mouse albumin enhancer/promoter, established at Jichi Medical School. National BioResource Project for the Rat in Japan, Rat Resource & Research Center
Proper citation: RRID:RRRC_00339 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155260364
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2022-10-06)
Alternate IDs: RGD_155260364, 155260364, RRRC_970, RRRC_0970, RRRC_00970
Notes: rat strain in which the rat Cyp3a1 gene (Cyp3a23-3a1, RGD:628626) was inactivated by insertion of a human CYP3A4 minigene (Cyp3A4*) and the linked rat Cyp3a2 locus was simultaneously mutated by CRISPR-mediated indel introduction. Strain contains Indel 8 at the Rat 3A2 locus (55 kb away), The CYP3A4 minigene included a CRISPR/Cas9 gene drive element to enable super-Mendelian inheritance. Strain contains and Active Genetic cassette which encodes a gRNA targeting the Rat 3A1 and 3A2 translation initiation site. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951
URL: URL: Doi:10.1101/2022.08.30.505951 Rat Resource and Research Center
Proper citation: RRID:RRRC_00970 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588572
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588572, 9588572, RRRC_730, RRRC_0730, RRRC_00730
Notes: The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00730 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641245
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-12-13)
Alternate IDs: RGD_155641245, 155641245, RRRC_975, RRRC_0975, RRRC_00975
Notes: Targeted knock-in adding a T2A-iCre to the Oprm1 (mu opioid receptor) in this cre recombinase reporter SD rat Rat Resource and Research Center
Proper citation: RRID:RRRC_00975 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588585
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588585, 9588585, RRRC_736, RRRC_0736, RRRC_00736
Notes: The transgene contains Cre recombinase expressed from cFos promoter and controllable by Tet activator/repressor Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00736 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358303
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_1358303, 1358303, RRRC_645, RRRC_0645, RRRC_00645
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00645 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358300
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_1358300, 1358300, RRRC_641, RRRC_0641, RRRC_00641
Notes: This transgenic strain carries a copy of mouse Rhodopsin gene with a proline to histidine substitution at codon 23 (c.68C>A). Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00641 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482286
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6482286, 6482286, RRRC_86, RRRC_086, RRRC_0086, RRRC_00086
Notes: insertion of EGFP transgene with Ubiquitin C promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00086 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482284
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: RGD_6482284, 6482284, RRRC_84, RRRC_084, RRRC_0084, RRRC_00084
Notes: insertion of EGFP transgene with Ubiquitin C promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00084 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=151356950
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_151356950, 151356950, RRRC_952, RRRC_0952, RRRC_00952
Notes: The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Initial SD rats were then bred onto Wistar background for >10 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center
Proper citation: RRID:RRRC_00952 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695032
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14695032, 14695032, RRRC_844, RRRC_0844, RRRC_00844
Notes: A CAG-loxP-mCherry-loxP-EGFP cassette was injected into SD zygote to generate this line. The integration site is not determined. This transgenic line could be mated to other rat lines that express Cre/CreER for lineage tracing. Rat Resource and Research Center
Proper citation: RRID:RRRC_00844 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521660
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_150521660, 150521660, RRRC_687, RRRC_0687, RRRC_00687
Notes: The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. A Rrrc substrain available at Rat Resource and Research Center
Proper citation: RRID:RRRC_00687 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695060
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14695060, 14695060, RRRC_780, RRRC_0780, RRRC_00780
Notes: Transgenic strain using Sleeping Beauty transposon germline transgenesis, ubiquitously expressing green fluorescent protein (GFP) under the rat eukaryotic translation elongation factor 1 alpha (Eef1a1) promoter. Two integration sites located on chromosome 8:28170658 and chromosome 1:276465837, both located in intronic gene areas, Jam3 (RGD:1303248) intron 1 and Vti1a (RGD:621490) intron 6, respectively. The Jam3 intron 1 is 51bp long, and the transgene resides at 37kb from exon 1 and 13kb from exon 2. In Vti1a intron 6, 102 bp long, the transgene is located at 81.4 kb from exon 5 and 21 kb from exon 6. Rat Resource and Research Center
Proper citation: RRID:RRRC_00780 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11040563
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_11040563, 11040563, RRRC_756, RRRC_0756, RRRC_00756
Notes: Cardiac specific overexpression of the alpha 1A adrenergic receptor, 40 fold overexpression of the receptor Rat Resource and Research Center
Proper citation: RRID:RRRC_00756 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11087549
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_11087549, 11087549, RRRC_764, RRRC_0764, RRRC_00764
Notes: random insertion of human GFAP promoter driving herpes simples virus thymidine kinase Rat Resource and Research Center
Proper citation: RRID:RRRC_00764 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641246
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_155641246, 155641246, RRRC_927, RRRC_0927, RRRC_00927
Notes: The transgene of LE-Tg(Cx3cr1-cre)3Ottc (RGD: 13441557) was crossed onto Fischer344 background by backcrossing the hybrid to Fischer344 and select for the presence of transgene. The donor LE transgenic was generated by microinjection of LE embyos with a BAC DNA containing the Cx3cr1-cre/ERT2 transgene which is composed of cre/ERT2 recombinase gene driven by the rat genomic Cx3cr1promoter. Rat Resource and Research Center
Proper citation: RRID:RRRC_00927 Copy
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