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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
http://www.taconic.com/transgenic-mouse-model/abb-knockouttransgenic-hla-dr4
Source Database: Taconic Biosciences
Affected Genes: histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Michael J Grusby
Availability: live
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: H2-Ab1
Proper citation: RRID:IMSR_TAC:4149 Copy
http://www.taconic.com/transgenic-mouse-model/fcer1g-fcrgamma-model-583
Source Database: Taconic Biosciences
Affected Genes: Fc receptor; IgE; high affinity I; gamma polypeptide
Genomic Alteration: targeted mutation 1; Jeffrey V Ravetch
Availability: live
Synonyms: B6.129P2-Fcer1g<tm1Rav>/Tac. Fcer1g (FcRgamma) CONSTITUTIVE KNOCK OUT - C57BL/6 Background
Notes: gene symbol note: Fc receptor; IgE; high affinity I; gamma polypeptide; mutant strain|congenic strain: Fcer1g
Proper citation: RRID:IMSR_TAC:583 Copy
http://www.taconic.com/transgenic-mouse-model/bcrp
Source Database: Taconic Biosciences
Affected Genes: ATP binding cassette subfamily G member 2 (Junior blood group)
Genomic Alteration: targeted mutation 1; Alfred H Schinkel
Availability: live
Notes: gene symbol note: ATP binding cassette subfamily G member 2 (Junior blood group); mutant strain|congenic strain: Abcg2
Proper citation: RRID:IMSR_TAC:2767 Copy
https://www.taconic.com/transgenic-mouse-model/il10-knockout-balbc
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:15660 Copy
https://www.taconic.com/rat-model/sod1-rat
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:2148 Copy
http://www.taconic.com/transgenic-mouse-model/appswe-model-2789
Source Database: Taconic Biosciences
Genomic Alteration: transgene insertion 2576; Karen Hsiao Ashe
Availability: live
Synonyms: APPSWE. 129S6.Cg-Tg(APPSWE)2576Kha/Tac
Notes: gene symbol note: ; mutant strain|congenic strain:
Proper citation: RRID:IMSR_TAC:2789 Copy
http://www.taconic.com/transgenic-mouse-model/mdr1ab-bcrp
Source Database: Taconic Biosciences
Affected Genes: ATP-binding cassette; sub-family B member 1A|ATP-binding cassette; sub-family B member 1B|ATP binding cassette subfamily G member 2 (Junior blood group)
Genomic Alteration: targeted mutation 1; Piet Borst|targeted mutation 1; Alfred H Schinkel
Availability: live
Synonyms: Mdr1a/b-Bcrp CONSTITUTIVE KNOCK OUT - FVB Background. FVB.129P2-Abcb1a<tm1Bor> Abcb1b<tm1Bor> Abcg2<tm1Ahs>/Tac
Notes: gene symbol note: ATP-binding cassette; sub-family B member 1A|ATP-binding cassette; sub-family B member 1B|ATP binding cassette subfamily G member 2 (Junior blood group); mutant strain|congenic strain: Abcb1a|Abcb1b|Abcg2
Proper citation: RRID:IMSR_TAC:3998 Copy
http://www.cfmice.org/cf-mouse-strains.html
Source Database: Cystic Fibrosis Mouse Model Core
Affected Genes: cystic fibrosis transmembrane conductance regulator
Genomic Alteration: endonuclease-mediated mutation 3; Case Western Reserve University
Availability: live
Notes: gene symbol note: cystic fibrosis transmembrane conductance regulator; coisogenic strain: Cftr
Proper citation: RRID:IMSR_CWR:CGX Copy
https://www.taconic.com/transgenic-mouse-model/apob100
Source Database: Taconic Biosciences
Genomic Alteration: transgene insertion 1102; Stephen G Young
Availability: live
Synonyms: ApoB100 MICROINJECTED - C57BL/6 Background. B6.Cg-Tg(APOB)1102Sgy/Tac
Notes: gene symbol note: ; mutant strain|congenic strain:
Proper citation: RRID:IMSR_TAC:1004 Copy
https://www.taconic.com/rat-model/lrrk2-g2019s
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:10681 Copy
https://www.taconic.com/transgenic-mouse-model/oatp1a1b-cluster-knockout-mouse
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:10707 Copy
http://www.cfmice.org/cf-mouse-strains.html
Source Database: Cystic Fibrosis Mouse Model Core
Affected Genes: cystic fibrosis transmembrane conductance regulator
Genomic Alteration: targeted mutation 1; Case Western Reserve University
Availability: live
Notes: gene symbol note: cystic fibrosis transmembrane conductance regulator; congenic strain: Cftr
Proper citation: RRID:IMSR_CWR:CFC Copy
The record is no longer available at this source.
Source Database: NSRRC, National Swine Resource and Research Center (NSRRC)
Genetic Background: domestic
Affected Genes: FANCA
Notes: KO of FANCA Exon 4 via zygote injection of the CRISPR Cas-9 system.
Proper citation: RRID:NSRRC_0075 Copy
https://www.jax.org/strain/008538
Source Database: JAX Mice and Services
Affected Genes: Cre recombinase and estrogen receptor 1 fusion gene|transgene insertion B; Akiko Nishiyama|chondroitin sulfate proteoglycan 4
Genomic Alteration: transgene insertion B; Akiko Nishiyama
Availability: live
Synonyms: NG2-CreER BAC transgenic mice (line B). NG2creER<TM>BAC transgenic mice
Notes: gene symbol note: Cre recombinase and estrogen receptor 1 fusion gene|transgene insertion B; Akiko Nishiyama|chondroitin sulfate proteoglycan 4; mutant strain|congenic strain: cre/Esr1|Tg(Cspg4-cre/Esr1*)BAkik|Cspg4
Proper citation: RRID:IMSR_JAX:008538 Copy
https://www.jax.org/strain/008684
Source Database: JAX Mice and Services
Affected Genes: recombination activating 1|tyrosinase-related protein 1|T cell receptor beta chain|transgene insertion 9; Nicholas P Restifo|T cell receptor alpha chain
Genomic Alteration: targeted mutation 1; Peter Mombaerts|white based brown|transgene insertion 9; Nicholas P Restifo
Availability: live
Notes: gene symbol note: recombination activating 1|tyrosinase-related protein 1|T cell receptor beta chain|transgene insertion 9; Nicholas P Restifo|T cell receptor alpha chain; congenic strain: Rag1|Tyrp1|Tcrb|Tg(Tcra;Tcrb)9Rest|Tcra
Proper citation: RRID:IMSR_JAX:008684 Copy
https://www.jax.org/strain/008766
Source Database: JAX Mice and Services
Affected Genes: |transgene insertion 1; Ichiro Taniuchi|CD8 subunit alpha
Genomic Alteration: transgene insertion 1; Ichiro Taniuchi
Availability: live
Notes: gene symbol note: |transgene insertion 1; Ichiro Taniuchi|CD8 subunit alpha; coisogenic strain: |Tg(Cd8a-cre)1Itan|Cd8a
Proper citation: RRID:IMSR_JAX:008766 Copy
https://www.jax.org/strain/009045
Source Database: JAX Mice and Services
Affected Genes: APC; WNT signaling pathway regulator
Genomic Alteration: targeted mutation 1; Tyler Jacks
Availability: live
Notes: gene symbol note: APC; WNT signaling pathway regulator; coisogenic strain: Apc
Proper citation: RRID:IMSR_JAX:009045 Copy
https://www.jax.org/strain/008805
Source Database: JAX Mice and Services
Affected Genes: calcium channel; voltage-dependent; alpha 1F subunit
Genomic Alteration: no b wave 9
Availability: live
Synonyms: B6(PWD)-Cacna1f<nob9>/Boc
Notes: gene symbol note: calcium channel; voltage-dependent; alpha 1F subunit; mutant strain: Cacna1f
Proper citation: RRID:IMSR_JAX:008805 Copy
https://www.jax.org/strain/009088
Source Database: JAX Mice and Services
Affected Genes: myeloid differentiation primary response gene 88
Genomic Alteration: targeted mutation 1.1; Anthony L DeFranco
Availability: live
Notes: gene symbol note: myeloid differentiation primary response gene 88; mutant strain|congenic strain: Myd88
Proper citation: RRID:IMSR_JAX:009088 Copy
https://www.jax.org/strain/009086
Source Database: JAX Mice and Services
Affected Genes: |gene trap ROSA 26; Philippe Soriano
Genomic Alteration: targeted mutation 1; Susan Dymecki
Availability: live
Synonyms: B6.129S4-Gt(ROSA)26Sor<tm1(FLP1)Dym>/JRainJ
Notes: gene symbol note: |gene trap ROSA 26; Philippe Soriano; congenic strain: |Gt(ROSA)26Sor
Proper citation: RRID:IMSR_JAX:009086 Copy
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