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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=329848999
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2023-06-07)
Alternate IDs: 329848999
Notes: This strain is established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Drd2 gene) into Long-Evans rat's fertile eggs. " National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_329848999 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092607
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092607
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092607 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092605
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092605
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092605 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=597538592
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 597538592
Notes: For the generation of transgenic rats, the authors used a 190-kb fused AF163864 PAC/AC097478 BAC clone (Yamakado et al., 2012, PMID:22475625). It contained the entire human SNCA sequence (GenBank AF163864), with 30-kb upstream regulatory promoter sequences and a 45-kb flanking downstream region, cloned into pBACe3.6 vector as described previously. Transgenic rats were obtained by injecting the purified BAC fragment into fertilized Sprague–Dawley oocytes at a concentration of 1.5 µg/ml. A founder line displaying the highest integration number of BAC DNA construct was crossedbred to homozygosity.
Proper citation: RRID:RGD_597538592 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405849386
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 405849386
Notes: This is the wild type littermate of the hDNMT3A transgenic rats which were established using zygote microinjection of a bacterial artificial chromosome (BAC). The RP11-159D24 BAC (NCBI-ID:223335, Homo sapiens, GRCh38.p2: Chr. 2: 25,202,642-25,410,145, total length: 207,504 bp) containing DNMT3A (GRCh38.p2: 25,232,961,25,342,590, total length: 109,630 bp) was injected into rat zygotes (Rattus norvegicus, Sprague-Dawley, SD). The offspring were identified with 8 PCR primer-pairs that were specific for the RP11-159D24 sequence to detect positive transgenic ones and wild type littermates that did not carry the human transgene.
Proper citation: RRID:RGD_405849386 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=617256277
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-07-23)
Alternate IDs: 617256277
Notes: Cryopreserved sperm was obtained and recovered for SD-Tg(Camk2a-cre/ERT2)ZiRrrc (RRRC_00688; RGD ID: 13446407), and then back-crossed to the outbred Long-evans (LE) strain for 8 generations. This transgenic strain is a tamoxifen inducible Cre recombinase animal in the Long-evans strain, with targeted cre/ERT2 fusion protein expression in neural populations, and is suitable for crossing with loxP models also in the LE strain. Rat Resource and Research Center
Proper citation: RRID:RGD_617256277 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=632522749
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 632522749
Notes: This transgenic rat strain carrying human NR3C2 was developed on a Sprague-Dawley albino background. The transgene was constructed with the human NR3C2 (also know as MR) under the proximal P1 promotor in the 5′-flanking regions of exons 1alpha.
Proper citation: RRID:RGD_632522749 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566458
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-07-01)
Alternate IDs: RGD_1566458, 1566458, RRRC_48, RRRC_048, RRRC_0048, RRRC_00048
Notes: F344 embryos were microinjected with R26-hPAP trangene which comprises of 0.8 kb genomic sequence of ROSA 26 promoter fused to human placental alkaline phosphatase (hPAP, ALPP). Rat Resource and Research Center
Proper citation: RRID:RRRC_00048 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=737703
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-07-08)
Alternate IDs: RGD_737703, 737703, RRRC_42, RRRC_042, RRRC_0042, RRRC_00042
Notes: Lewis from CRL were used as the background strain. This strain was made by pronuclear injection into Lewis embryos. The embryos were coinjected with DNA fragments containing the HLA-B*0702 human gene and the human beta-2-microglobulin gene. Founder 120-4 was selected and carrier animals from this founder were mated and this strain was bred to homozygosity. Rat Resource and Research Center
Proper citation: RRID:RRRC_00042 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1300439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-07-10)
Alternate IDs: RGD_1300439, 1300439, RRRC_65, RRRC_065, RRRC_0065, RRRC_00065
Notes: This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into SD rat embryos. Animals that exhibited fluorescence of tails where then mated. The colony was transferred from Carlos Lois, California Institute of Technology, Pasedena, California to the Rat Resource and Research Center in 2002. This strain has been maintained by backcrossing carrier males to SD stock females in order to segregate transgenes and maintain the SD background. The strain now carries a single transgene which is located at chromosome 14q21. Rat Resource and Research Center
Proper citation: RRID:RRRC_00065 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6478791
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6478791, 6478791, RRRC_307, RRRC_0307, RRRC_00307
Notes: This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into Lewis rat embryos. Animals that exhibited fluorescence of tails were mated. Offspring were bred with Lewis wild-type mates to map transgene location. Animals were backcrossed 10 generations onto F344. Rat Resource and Research Center
Proper citation: RRID:RRRC_00307 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2304211
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo (as of 2018-07-16)
Alternate IDs: RGD_2304211, 2304211, RRRC_301, RRRC_0301, RRRC_00301
Notes: This strain expresses the cre recombinase ubiquitously driven by CAG promoter. The majority of expression of the transgene is detected in the skeletal muscles established at Jichi Medical School. National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Proper citation: RRID:RRRC_00301 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247278
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-18)
Alternate IDs: RGD_7247278, 7247278, RRRC_655, RRRC_0655, RRRC_00655
Notes: Camk2a-tTA transgenic rats expressing tTA under regulatory control of the forebrain promotor Camk2a. Transgene expression can be blocked by administration of doxycycline to drinking water. Rat Resource and Research Center
Proper citation: RRID:RRRC_00655 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247289
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-18)
Alternate IDs: RGD_7247289, 7247289, RRRC_650, RRRC_0650, RRRC_00650
Notes: SD embryos were microinjected with a DNA construct containing the GFP gene downstream of a miniCMV promoter under the control of tetracycline response element (TRE). The pLV-Tet-GFP was generated by co-transfection of pLV-Tet-GFP, pÎ8.9 and pVSV-G into a 293FT packaging cell line Rat Resource and Research Center
Proper citation: RRID:RRRC_00650 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7247290
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-08-22)
Alternate IDs: RGD_7247290, 7247290, RRRC_627, RRRC_0627, RRRC_00627
Notes: SD embryos were microinjected with a lentiviral construct containing the rat P2ry2 gene (G protein-coupled purinergic receptor P2Y2) under control of an ubiquitin-C promoter. Results in over-expression of P2ry2 mRNA. Rat Resource and Research Center
Proper citation: RRID:RRRC_00627 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2304311
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo (as of 2017-08-08)
Alternate IDs: RGD_2304311, 2304311, RRRC_298, RRRC_0298, RRRC_00298
Notes: This strain expresses LacZ ubiquitously driven by the gene trap ROSA26 promoter established at Jichi Medical School. National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Proper citation: RRID:RRRC_00298 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482680
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-04-12)
Alternate IDs: RGD_6482680, 6482680, RRRC_365, RRRC_0365, RRRC_00365
Notes: Hsd:SD background carrying a transgene which produces over-expression of the rat Erbb2 proto-oncogene under the control of the mouse mammary tumor virus (MMTV) long terminal repeat. Rat Resource and Research Center
Proper citation: RRID:RRRC_00365 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482282
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: RGD_6482282, 6482282, RRRC_83, RRRC_083, RRRC_0083, RRRC_00083
Notes: insertion of EGFP transgene with Ubiquitin C promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00083 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695054
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2019-07-01)
Alternate IDs: RGD_14695054, 14695054, RRRC_795, RRRC_0795, RRRC_00795
Notes: Rat Resource and Research Center
Proper citation: RRID:RRRC_00795 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13462045
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2024-01-17)
Alternate IDs: RGD_13462045, 13462045, RRRC_830, RRRC_0830, RRRC_00830
Notes: Pronuclear injection was used to introduce an expression cassette containing the Thy-1 enhancer and GCaMP6f protein coding sequence. GCaMP6f is a genetically encoded calcium indicator. It is a synthetic fusion of green fluorescent protein, calmodulin, and M13, a peptide sequence from myosin light-chain kinase. Rat Resource & Research Center
Proper citation: RRID:RRRC_00830 Copy
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