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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062768
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: mirSi34 II; unc-119(ed3) III.
Notes: Made_by: Neus Sanfeliu Cerdan|"mirSi34 [myo-3p::lox2272::mtagBFP2::tbb-2 3'UTR::lox2272::ChR2-HRDC::SL2::jRGECO1a::let-858 3'UTR + Cbr-unc-119(+)] II. Blue fluorescence in body wall muscles. Combine with CRE driven by a promoter expressed in desired muscle cells to switch from blue expression to ChR2-HRDC and jRGECO1a expression. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651."
Proper citation: RRID:WB-STRAIN:WBStrain00062768 Copy
http://www.wormbase.org/db/get?name=WBStrain00062758
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: mirSi16 II; unc-119(ed3) III; mirIs110 V; mirIs107.
Notes: mirSi16 [flp-18p::lox2272::BFP::tbb-2 3'UTR::lox2272::ChR2-HRDC::SL2::jRGECO1a::unc-54 3'UTR + Cbr-unc-119(+)] II. mirIs110 [odr-7p::TeNL + unc-122p::GFP *oxTi553 [eft-3p::tdTomato::H2B::unc-54 3'UTR + Cbr-unc-119(+)]] V. mirIs107 [gpa:14p::CRE + npr-9p::ChR-HRDC::YFP::SL2::jRGECO1a + rps-0p::hygroR]. Blue fluorescence in flp-18 expressing neurons. Green coelomycetes segregates with calcium sensitive (Kd 250 nM) teal nanolantern (TeNL) in AWA. ChR2-HRDC and jRGECO1a in AVA (instead of BFP) and ChR2-HRDC::YFP and jRGECO1a in AIB. HygroR. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651.
Proper citation: RRID:WB-STRAIN:WBStrain00062758 Copy
http://www.wormbase.org/db/get?name=WBStrain00062759
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: mirSi16 II; unc-119(ed3) III.
Notes: mirSi16 [flp-18p::lox2272::BFP::tbb-2 3'UTR::lox2272::ChR2-HRDC::SL2::jRGECO1a::unc-54 3'UTR + Cbr-unc-119(+)] II. Blue fluorescence in flp-18 expressing neurons. Combine with CRE driven by a promoter co-expressed in flp-18 expressing cells to switch from blue expression to ChR2-HRDC and jRGECO1a expression. Reference: Porta-de-la-Riva M, et al. Nat Methods. 2023 May;20(5):761-769. doi: 10.1038/s41592-023-01836-9. PMID: 37024651.
Proper citation: RRID:WB-STRAIN:WBStrain00062759 Copy
http://www.wormbase.org/db/get?name=WBStrain00062750
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; qbcSi12 IV.
Notes: qbcSi112 [elt-2p::GFP::his-58::3XmiR-228(mut)::tbb-2 3UTR + unc-119(+)] IV. Somatic miR-228 miRNA GFP reporter with a mutation in the miRNA-binding site. Reference: Dallaire et al. Dev Cell. 2018 Oct 22;47(2):239-247.e4. doi: 10.1016/j.devcel.2018.08.022. PMID: 30245155.
Proper citation: RRID:WB-STRAIN:WBStrain00062750 Copy
http://www.wormbase.org/db/get?name=WBStrain00062751
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; qbcSi11 IV.
Notes: qbcSi11 [elt-1p::GFP::his-58::3XmiR-228::tbb-2 3UTR + unc-119(+)] IV. Somatic miR-228 miRNA GFP reporter. Reference: Dallaire et al. Dev Cell. 2018 Oct 22;47(2):239-247.e4. doi: 10.1016/j.devcel.2018.08.022. PMID: 30245155.
Proper citation: RRID:WB-STRAIN:WBStrain00062751 Copy
http://www.wormbase.org/db/get?name=WBStrain00062749
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; qbcSi10 IV.
Notes: qbcSi10 [mex-5p::GFP::his-58::3XmiR-228(mut)::tbb-2 3UTR + unc-119(+)] IV. Germline-specific miR-228 miRNA GFP reporter with a mutation in the miRNA-binding site. Reference: Dallaire et al. Dev Cell. 2018 Oct 22;47(2):239-247.e4. doi: 10.1016/j.devcel.2018.08.022. PMID: 30245155.
Proper citation: RRID:WB-STRAIN:WBStrain00062749 Copy
http://www.wormbase.org/db/get?name=WBStrain00063396
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(tm4063) III; ltIs44 V; stIs10024; zuIs178; zzyIs139.
Notes: ltIs44 [pie-1p::mCherry::PH(PLC1delta1) + unc-119(+)] V. stIs10024 [pie-1::H2B::GFP::pie-1 3' UTR + unc-119(+)]. zuIs178 [his-72(1kb 5' UTR)::his-72::SRPVAT::GFP::his-72 (1KB 3' UTR) + 5.7 kb XbaI - HindIII unc-119(+)]. zzyIs139 [his-72p::PH(PLC1delta1)::mCherry::pie-1 3' UTR + unc-119(+)]. Reference: Zhao Z, et al. https:
Proper citation: RRID:WB-STRAIN:WBStrain00063396 Copy
http://www.wormbase.org/db/get?name=WBStrain00003782
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: crgSi2081 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:BCN2081, CGC_BCN2081
Notes: crgSi2081 [rpl-28p::PuroR + myo-2p::GFP + Cbr-unc-119(+)] II. Superficially wild-type. Puromycin resistant. ttTi5605 transposon in EG4322 has been replaced by a single copy insertion crgSi2081. Reference: Semple JI, et al., Nat Methods. 2010 Sep;7(9):725-7.
Proper citation: RRID:WB-STRAIN:WBStrain00003782 Copy
http://www.wormbase.org/db/get?name=WBStrain00003871
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; bqSi711 IV.
Alternate IDs: WB-STRAIN:BN711, CGC_BN711
Notes: bqSi711 [mex-5p::FLP::SL2::mNG + unc-119(+)] IV. Constitutive co-expression of codon-optimised FLP and fluorescent mNeonGreen in the germ line. Reference: Macias-Leon J & Askjaer P. (2018): Efficient FLP-mediated germ-line recombination in C. elegans. Micropublication:biology. Dataset. https:|"Made_by: Javier Macas-Len"
Proper citation: RRID:WB-STRAIN:WBStrain00003871 Copy
http://www.wormbase.org/db/get?name=WBStrain00004055
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:32550513, PMID:32550493, PMID:33300872, PMID:34505574, PMID:34663906, PMID:34865044, PMID:37507441, PMID:38282418, PMID:38878287
Synonyms: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II.
Alternate IDs: WB-STRAIN:CA1200, CGC_CA1200
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the soma. This strain can be used for auxin-inducible degradation (AID) in somatic tissues. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.|"WBStrain provided so WBPaper00060223 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00060754 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061869 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00062146 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00004055 Copy
http://www.wormbase.org/db/get?name=WBStrain00004063
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37507441
Synonyms: ieSi61 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1209, CGC_CA1209
Notes: ieSi61 [ges-1p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the intestine. This strain can be used for auxin-inducible degradation (AID) in the intestine. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004063 Copy
http://www.wormbase.org/db/get?name=WBStrain00004073
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37708895
Synonyms: ieSi68 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1472, CGC_CA1472
Notes: ieSi68 [sun-1p::TIR1::mRuby::htp-1 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing a modified Arabidopsis thaliana TIR1 tagged with mRuby in the germ line and early embryos. This strain can be used for auxin-inducible degradation (AID) in germ line and early embryos. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.|"Supplementary_genotype ieSi68[sun-1p::TIR1::mRuby::htp-1 3'UTR + Cbr-unc-119(+)] II; unc-119(ed3) III"
Proper citation: RRID:WB-STRAIN:WBStrain00004073 Copy
http://www.wormbase.org/db/get?name=WBStrain00004072
Source Database: WormBase (WB)
Affected Genes: WBGene00006311(sun-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00006311(sun-1), WBGene00006843(unc-119)
Availability: available
Source References: PMID:37436986
Synonyms: ieSi65 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1353, CGC_CA1353
Notes: ieSi65 [sun-1p::TIR1::sun-1 3UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing a modified Arabidopsis thaliana TIR1 in germ line and early embryos. This strain can be used for auxin-inducible degradation (AID) in germ line and early embryos. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004072 Copy
http://www.wormbase.org/db/get?name=WBStrain00004068
Source Database: WormBase (WB)
Affected Genes: WBGene00006377(syp-3)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00006377(syp-3), WBGene00006843(unc-119)
Availability: available
Synonyms: syp-3(ok758) I; ieSi11 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1218, CGC_CA1218
Notes: ieSi11 [syp-3p::EmeraldGFP::syp-3::syp-3 3'UTR + Cbr-unc-119(+)] II. ieSi11 was inserted into ttTi5605 II using MosSCI. Expression of GFP::SYP-3 largely complements syp-3(ok758), but some meiotic nondisjunction is detected above the N2 background (85% embryonic viability; ~1% male self-progeny;). GFP::SYP-3 expression is readily detected in spermatocytes and oocytes in the germline, and localizes to the interface between paired homologous chromosomes during most of meiotic prophase. Reference: Rog O, Dernburg AF. Cell Rep. 2015 Mar 10. pii: S2211-1247(15)00178-3.
Proper citation: RRID:WB-STRAIN:WBStrain00004068 Copy
http://www.wormbase.org/db/get?name=WBStrain00004705
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; eEx650.
Alternate IDs: WB-STRAIN:CB6710, CGC_CB6710
Notes: eEx650 [ilys-3p::GFP + unc-119(+)]. Pick wild-type to maintain. Transcriptional reporter transgene for ilys-3. Reference: Gravato-Nobre et al. (2016) PMID: 27525822.|"Made_by: M J Gravato-Nobre"|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00004705 Copy
http://www.wormbase.org/db/get?name=WBStrain00004719
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; eEx650.
Alternate IDs: WB-STRAIN:CB6785, CGC_CB6785
Notes: eEx650 [ilys-4p::GFP + unc-119(+)]. Transcriptional reporter for ilys-4. Reference: Gravato-Nobre et al. (2016) PMID: 27525822.|"Made_by: M J Gravato-Nobre"
Proper citation: RRID:WB-STRAIN:WBStrain00004719 Copy
http://www.wormbase.org/db/get?name=WBStrain00004798
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; cerIs7.
Alternate IDs: WB-STRAIN:CER162, CGC_CER162
Notes: cerIs7 [lsm-1::GFP(fosmid) + unc-119(+)]. cerIs7 rescues all the temperature-sensitive phenotypes of lsm-1(tm3585). Reporter contains full-length lsm-1 tagged with GFP. GFP was inserted into a fosmid containing lsm-1. GFP is expressed diffusely in the cytoplasm of somatic cells. Under heat shock conditions, GFP accumulates forming cytoplasmic foci. Reference: Cornes E, et al. RNA. 2015 Sep;21(9):1544-53.
Proper citation: RRID:WB-STRAIN:WBStrain00004798 Copy
http://www.wormbase.org/db/get?name=WBStrain00004796
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; cerIs2.
Alternate IDs: WB-STRAIN:CER41, CGC_CER41
Notes: cerIs2 [lsm-4p::lsm-4::GFP::lsm-4 3'UTR + unc-119(+)]. Reporter contains full-length lsm-4 tagged with GFP. GFP was inserted into a fosmid containing lsm-4. Ubiquitous nuclear GFP expression in somatic and germ cells under normal growth conditions. Cytoplasmic GFP accumulation after exposure to heat-shock. Reference: Cornes E, et al. RNA. 2015 Sep;21(9):1544-53.
Proper citation: RRID:WB-STRAIN:WBStrain00004796 Copy
http://www.wormbase.org/db/get?name=WBStrain00004720
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; eEx671.
Alternate IDs: WB-STRAIN:CB6786, CGC_CB6786
Notes: eEx671 [ilys-5p::GFP; unc-119(+)]. Pick wild-type (non-Unc) to maintain. Transcriptional reporter for ilys-5. Reference: Gravato-Nobre et al. (2016) PMID: 27525822.|"Made_by: M J Gravato-Nobre"
Proper citation: RRID:WB-STRAIN:WBStrain00004720 Copy
http://www.wormbase.org/db/get?name=WBStrain00004753
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00017577(bah-2)
Genomic Alteration: WBGene00006843(unc-119), WBGene00017577(bah-2)
Availability: available
Synonyms: unc-119(ed3) III; bah-2(gk487599) IV; eEx835.
Alternate IDs: WB-STRAIN:CB7401, CGC_CB7401
Notes: eEx835 [bah-2(+) + unc-119(+)]. Pick wild-type to maintain. bah-2(gk487599) rescued by transgene. Reference: O'Rourke et al (in preparation).
Proper citation: RRID:WB-STRAIN:WBStrain00004753 Copy
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