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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00042118
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: Cbr-unc-119(st20000) III; zzyIs49 IV.
Alternate IDs: WB-STRAIN:ZZY49, CGC_ZZY49
Notes: Non-elegans Strain|"zzyIs49 [Cbr-myo-2p::GFP + Cbr-unc-119(+)] IV. Transgene inserted into RW20000 Cbr-unc-119. Insertion site is between 0 and 9.85 Mb on Chromosome IV. Reference: Bi Y, et al. PLoS Genet. 2015 Feb 18;11(2):e1004993."
Proper citation: RRID:WB-STRAIN:WBStrain00042118 Copy
http://www.wormbase.org/db/get?name=WBStrain00042115
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: Cbr-unc-119(st20000) III; zzyIs34 X.
Alternate IDs: WB-STRAIN:ZZY33, CGC_ZZY33
Notes: Non-elegans Strain|"zzyIs34 [Cbr-myo-2p::GFP + Cbr-unc-119(+)] X. Transgene inserted into RW20000 Cbr-unc-119. Insertion site is between 0 and 2.37 Mb on Chromosome X. Reference: Bi Y, et al. PLoS Genet. 2015 Feb 18;11(2):e1004993."
Proper citation: RRID:WB-STRAIN:WBStrain00042115 Copy
http://www.wormbase.org/db/get?name=WBStrain00042114
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: Cbr-unc-119(st20000) III; zzyIs31 IV.
Alternate IDs: WB-STRAIN:ZZY31, CGC_ZZY31
Notes: Non-elegans Strain|"zzyIs31 [Cbr-myo-2p::GFP + Cbr-unc-119(+)] IV. Transgene inserted into RW20000 Cbr-unc-119. Insertion site is between 1.5 and 9.85 Mb on Chromosome IV. Reference: Bi Y, et al. PLoS Genet. 2015 Feb 18;11(2):e1004993."
Proper citation: RRID:WB-STRAIN:WBStrain00042114 Copy
http://www.wormbase.org/db/get?name=WBStrain00043478
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; kpIs100.
Alternate IDs: CGC_IT1187
Notes: Generated based on CalTech XREF data|"kpIs100 [pie-1p::Ub(G76V)::GFP::H2B::drp-1 3' UTR + unc-119(+)]. [NOTE: (4/4/2025): Strain segregates Dpy, Rol, and non-Rol, possibly due to a background dpy-10 mutation; bothexpress GFP as expected. It was recommended that non-Rollers be picked when maintaining the strain.] Expresses Ubiquitin::GFP fusion protein in the germ line. The last amino acid of ubiquitin is mutated to valine (G76V), which prevents the cleavage of ubiquitin from GFP by the deubiqutinating enzymes and renders the GFP constitutively targeted for degradation by the proteasome. The strain can be used to assay proteasome activity in the germ line. Reference: Kumar GA & Subramaniam K. Development. 2018 Mar 29;145(7):dev163949. PMID: 29540500"
Proper citation: RRID:WB-STRAIN:WBStrain00043478 Copy
http://www.wormbase.org/db/get?name=WBStrain00044397
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: ltSi1 II; unc-119(ed3) III.
Alternate IDs: CGC_OD334
Notes: Generated based on CalTech XREF data|"ltSi1 [knl-1p::knl-1(re-encoded)::RFP + Cbr-unc-119(+)] II. KNL-1::RFP has been re-coded to be knl-1(RNAi) resistant. Reference: Espeut J, et al. Cell Rep. 2015 Jul 7;12(1):58-65. doi: 10.1016/j.celrep.2015.05.039. PMID: 26119738"|"Made_by: Arshad Desai lab"
Proper citation: RRID:WB-STRAIN:WBStrain00044397 Copy
http://www.wormbase.org/db/get?name=WBStrain00044684
Source Database: WormBase (WB)
Affected Genes: WBGene00004976(spe-41)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004976(spe-41), WBGene00006843(unc-119)
Availability: unknown
Synonyms: yokSi3 II; spe-41(sy693) unc-119(ed3) III.
Notes: Generated based on CalTech XREF data|"yokSi3 [spe-11p::trp-3A::TagRFP-T::tbb-2 3'UTR + Cbr-unc-119(+)] II. Reference: Takayama J & Onami S. Cell Rep. 2016 Apr 19;15(3):625-637."
Proper citation: RRID:WB-STRAIN:WBStrain00044684 Copy
http://www.wormbase.org/db/get?name=WBStrain00063396
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(tm4063) III; ltIs44 V; stIs10024; zuIs178; zzyIs139.
Notes: ltIs44 [pie-1p::mCherry::PH(PLC1delta1) + unc-119(+)] V. stIs10024 [pie-1::H2B::GFP::pie-1 3' UTR + unc-119(+)]. zuIs178 [his-72(1kb 5' UTR)::his-72::SRPVAT::GFP::his-72 (1KB 3' UTR) + 5.7 kb XbaI - HindIII unc-119(+)]. zzyIs139 [his-72p::PH(PLC1delta1)::mCherry::pie-1 3' UTR + unc-119(+)]. Reference: Zhao Z, et al. https:
Proper citation: RRID:WB-STRAIN:WBStrain00063396 Copy
http://www.wormbase.org/db/get?name=WBStrain00054981
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi220 I; ltSi1232 II; unc-119(ed3) III.
Notes: ltSi220 [mex-5p::GFP::tbb-2::operon-linker::mCherry::his-11 + Cbr-unc-119(+)] I. ltSi1232 [spd-2p::spd-5(S170A T178A T198A)::spd-5 3'UTR + Cbr-unc-119(+)] II. mCherry-labeled histones. GFP-labeled microtubules. Reference: Ohta M, et al. J Cell Biol. 2021 Feb 1;220(2):e202009083. doi: 10.1083/jcb.202009083. PMID: 33399854.
Proper citation: RRID:WB-STRAIN:WBStrain00054981 Copy
http://www.wormbase.org/db/get?name=WBStrain00054983
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi220 I; ltSi1561 II; unc-119(ed3) III.
Notes: ltSi220 [mex-5p::GFP::tbb-2::operon-linker::mCherry::his-11 + Cbr-unc-119(+)] I. ltSi1561 [spd-2p::spd-5(S170A T178A T198A S653A S658A)::spd-5 3'UTR + Cbr-unc-119(+)] II. mCherry-labeled histones. GFP-labeled microtubules. Reference: Ohta M, et al. J Cell Biol. 2021 Feb 1;220(2):e202009083. doi: 10.1083/jcb.202009083. PMID: 33399854.
Proper citation: RRID:WB-STRAIN:WBStrain00054983 Copy
http://www.wormbase.org/db/get?name=WBStrain00054987
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi264 II; unc-119(ed3) III.
Notes: ltSi264 [bub-1p::bub-1(re-encoded)::RFP + Cbr-unc-119(+)] II. BUB-1::RFP has been re-coded to be knl-1(RNAi) resistant. Reference: Pelisch F, et al. Mol Cell. 2017 Jan 5;65(1):66-77. doi: 10.1016/j.molcel.2016.11.001. PMID: 27939944|"Made_by: Arshad Desai lab"
Proper citation: RRID:WB-STRAIN:WBStrain00054987 Copy
http://www.wormbase.org/db/get?name=WBStrain00054966
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi597 I; unc-119(ed3) III.
Notes: ltSi597 [knl-1p::knl-1::mCherry::knl-1 3'UTR Cbr-unc-119(+)] I. mCherry labeled KNL-1. Reference: Hattersley et al., Dev Cell 2016 Sep 12;38(5):463-77. doi: 10.1016/j.devcel.2016.08.006. PMID: 27623381|"Made_by: Arshad Desai lab"
Proper citation: RRID:WB-STRAIN:WBStrain00054966 Copy
http://www.wormbase.org/db/get?name=WBStrain00054968
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi569 I; ltSi1141 II; unc-119(ed3) III.
Notes: ltSi569 [CEOP3608 tbg-1::mCherry + Cbr-unc-119(+)] inserted into oxTi185 [ttTi5605 + NeoR(+) + unc-18(+)] I. ltSi1141 [spd-2p::gfp::spd-5(re-encoded) + Cbr-unc-119(+)] II. Re-encoded spd-5 is siRNA-resistant. mCherry-labeled gamma tubulin. GFP-labeled centrioles. Reference: Woodruff JB, et al. Science. 2015 May 15;348(6236):808-12. doi: 10.1126/science.aaa3923. PMID: 25977552
Proper citation: RRID:WB-STRAIN:WBStrain00054968 Copy
http://www.wormbase.org/db/get?name=WBStrain00029956
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wgIs18.
Alternate IDs: WB-STRAIN:OP18, CGC_OP18
Notes: Generated from Paper data WBPaper00060123|"Made_by: modEncode"|"Modern strain"|"wgIs18 [lin-39::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of lin-39 coding sequence of fosmid ID#WRM0616aE11 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029956 Copy
http://www.wormbase.org/db/get?name=WBStrain00029958
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wgIs27.
Alternate IDs: WB-STRAIN:OP27, CGC_OP27
Notes: Generated from Paper data WBPaper00060123|"Made_by: modEncode"|"Modern strain"|"wgIs27 [mab-5::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of mab-5 coding sequence of fosmid ID#WRM0640bH09 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029958 Copy
http://www.wormbase.org/db/get?name=WBStrain00029979
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wgIs62.
Alternate IDs: WB-STRAIN:OP62, CGC_OP62
Notes: Made_by: modEncode|"Modern strain"|"wgIs62 [lin-11::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029979 Copy
http://www.wormbase.org/db/get?name=WBStrain00029976
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:32628333
Synonyms: unc-119(ed3) III; gaEx290.
Alternate IDs: WB-STRAIN:OP56, CGC_OP56
Notes: gaEx290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. Pick non-Unc to maintain. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)|"gaEx290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"gaIs290 [elt-2::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Recombineered fosmid was integrated by biolistic bombardment. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Mann F, et al. PLoS. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"|"Made_by: modENCODE"|"Modern strain"|"WBStrain mapped, WBPaper00059970 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00029976 Copy
http://www.wormbase.org/db/get?name=WBStrain00029968
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37643611
Synonyms: unc-119(ed3) III; wgIs43.
Alternate IDs: WB-STRAIN:OP43, CGC_OP43
Notes: Made_by: modEncode|"Modern strain"|"Supplementary_genotype unc-119(ed3) III; wgIs43[nhr-23::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]"|"wgIs43 [nhr-23::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Gerstein MB, et al. Science. 2010 Dec 24;330(6012):1775-87. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029968 Copy
http://www.wormbase.org/db/get?name=WBStrain00029964
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wgIs34.
Alternate IDs: WB-STRAIN:OP34, CGC_OP34
Notes: Made_by: modEncode|"wgIs34 [ama-1::TY1::EGFP::3xFLAG + unc-119(+)]. Slightly Dpy. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of ama-1 coding sequence of fosmid ID#WRM0610dA01 by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029964 Copy
http://www.wormbase.org/db/get?name=WBStrain00029999
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wgIs92.
Alternate IDs: WB-STRAIN:OP92, CGC_OP92
Notes: Made_by: EAP/DKV/JIM|"Modern strain"|"wgIs92 [sdc-2::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00029999 Copy
http://www.wormbase.org/db/get?name=WBStrain00029995
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wgIs86.
Alternate IDs: WB-STRAIN:OP86, CGC_OP86
Notes: Made_by: modEncode|"Modern strain"|"wgIs86 [peb-1::TY1::EGFP::3xFLAG(92C12) + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov, M, et al. Nat Methods (2006) 10:839-44. Gerstein MB, et al. Science. 2010 Dec 24;330(6012):1775-87. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)"
Proper citation: RRID:WB-STRAIN:WBStrain00029995 Copy
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