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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00026686
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)
Genomic Alteration: WBGene00000898(daf-2)
Availability: available
Synonyms: daf-2(e1370) III; hqIs180.
Alternate IDs: WB-STRAIN:MQD774, CGC_MQD774
Notes: hqIs180 [sdhb-1p::mtLS::cpYFP + rol-6(su1006)]. Rollers. About two mitoflash events per anterior pharynx per 200 seconds on adult day 3 when cultured on standard NGM plates at 20 C. In hqIs180, mtLS is a mitochondrial localization sequence from SDHB-1 and cpYFP is circularly permuted yellow fluorescent protein, a superoxide sensor (Wang W. et al., Cell, 2008). The cpYFP signal is detected in most or all tissues, but most strongly in the pharyngeal muscles. Reference: Shen E-Z, et al. Nature. 2014 Feb 12. doi: 10.1038/nature13012.|"Made_by: E-Z Shen & C-Q Song"
Proper citation: RRID:WB-STRAIN:WBStrain00026686 Copy
http://www.wormbase.org/db/get?name=WBStrain00026603
Source Database: WormBase (WB)
Affected Genes: WBGene00015349(henn-1)
Genomic Alteration: WBGene00015349(henn-1)
Availability: available
Synonyms: lucSi28 II; henn-1(tm4477) III.
Alternate IDs: WB-STRAIN:MLC528, CGC_MLC528
Notes: lucSi28 [myo-2p::HEN1::unc-54 3UTR + Cbr-unc-119(+)] II. Superficially wild-type. Cell-type-specific 3'-terminal 2'-O-methylation of animal miRNAs by a genetically encoded plant-specific methyltransferase (Arabidopsis thaliana HEN1). NOTE: This strain might still carry unc-119(ed3) in the background. Reference: Alberti C, et al. Nat Methods. 2018 Feb 26. doi: 10.1038/nmeth.4610.|"Made_by: Chiara Alberti"|"No mutagen used"
Proper citation: RRID:WB-STRAIN:WBStrain00026603 Copy
http://www.wormbase.org/db/get?name=WBStrain00026602
Source Database: WormBase (WB)
Affected Genes: WBGene00006742(unc-2)
Genomic Alteration: WBGene00006742(unc-2)
Availability: available
Synonyms: unc-2(luc27) X.
Alternate IDs: WB-STRAIN:MLC524, CGC_MLC524
Notes: luc27 is a 300 bp deletion in the unc-2 3'UTR. Reference: Drexel T, et al. Genes Dev. 2016 Sep 15;30(18):2042-2047.|"Made_by: Drexel Tanja"
Proper citation: RRID:WB-STRAIN:WBStrain00026602 Copy
http://www.wormbase.org/db/get?name=WBStrain00026682
Source Database: WormBase (WB)
Affected Genes: WBGene00001096(dsc-1)
Genomic Alteration: WBGene00001096(dsc-1)
Availability: available
Synonyms: dsc-1(tm241) X.
Alternate IDs: WB-STRAIN:MQ1444, CGC_MQ1444
Notes: Mutagen:UV/TMP|"Pale. Short defecation cycle length. Expulsion defective."
Proper citation: RRID:WB-STRAIN:WBStrain00026682 Copy
http://www.wormbase.org/db/get?name=WBStrain00026675
Source Database: WormBase (WB)
Affected Genes: WBGene00000536(clk-1)|WBGene00014302(rte-5)
Genomic Alteration: WBGene00000536(clk-1), WBGene00014302(rte-5)
Availability: available
Synonyms: clk-1(e2519) III; rte-5(qm197) X.
Alternate IDs: WB-STRAIN:MQ1236, CGC_MQ1236
Notes: Made_by: David Shanks|"qm197 suppresses the L2 arrest and sterility of clk-1(e2519) on UQ- bacteria."
Proper citation: RRID:WB-STRAIN:WBStrain00026675 Copy
http://www.wormbase.org/db/get?name=WBStrain00026674
Source Database: WormBase (WB)
Affected Genes: WBGene00000912(daf-16)|WBGene00002162(isp-1)
Genomic Alteration: WBGene00000912(daf-16), WBGene00002162(isp-1)
Availability: available
Synonyms: daf-16(m26) I; isp-1(qm150) IV.
Alternate IDs: WB-STRAIN:MQ1050, CGC_MQ1050
Notes: Made_by: Jin Liu Feng|"Slow development."
Proper citation: RRID:WB-STRAIN:WBStrain00026674 Copy
http://www.wormbase.org/db/get?name=WBStrain00026679
Source Database: WormBase (WB)
Affected Genes: WBGene00000536(clk-1)|WBGene00014586(rte-2)
Genomic Alteration: WBGene00000536(clk-1), WBGene00014586(rte-2)
Availability: available
Synonyms: rte-2(qm210) I; clk-1(e2519) III.
Alternate IDs: WB-STRAIN:MQ1403, CGC_MQ1403
Notes: qm210 suppresses the growth arrest and sterility of clik-1(e2519) on UQ- bacteria.
Proper citation: RRID:WB-STRAIN:WBStrain00026679 Copy
http://www.wormbase.org/db/get?name=WBStrain00026678
Source Database: WormBase (WB)
Affected Genes: WBGene00000536(clk-1)|WBGene00004708(rte-1)
Genomic Alteration: WBGene00000536(clk-1), WBGene00004708(rte-1)
Availability: available
Synonyms: clk-1(e2519) III; rte-1(qm199) X.
Alternate IDs: WB-STRAIN:MQ1395, CGC_MQ1395
Notes: qm199 suppresses the growth arrest and sterility of clik-1(e2519) on ubi- bacteria.
Proper citation: RRID:WB-STRAIN:WBStrain00026678 Copy
http://www.wormbase.org/db/get?name=WBStrain00026626
Source Database: WormBase (WB)
Affected Genes: WBGene00001323(enu-2)
Genomic Alteration: WBGene00001323(enu-2)
Availability: available
Source References: PMID:9210792
Synonyms: enu-2(lb140) III.
Alternate IDs: WB-STRAIN:MP140, CGC_MP140
Notes: Mildly Unc. Adults display progressive vacuolization of body wall muscle. Neither phenotype is suppressed by mec-6(e1342).
Proper citation: RRID:WB-STRAIN:WBStrain00026626 Copy
http://www.wormbase.org/db/get?name=WBStrain00026621
Source Database: WormBase (WB)
Affected Genes: WBGene00006347(sup-42)
Genomic Alteration: WBGene00006347(sup-42)
Availability: available
Source References: PMID:9210792
Synonyms: sup-42(lb88) X.
Alternate IDs: WB-STRAIN:MP88, CGC_MP88
Notes: Made_by: Kambiz Shekdar|"WT."
Proper citation: RRID:WB-STRAIN:WBStrain00026621 Copy
http://www.wormbase.org/db/get?name=WBStrain00026620
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003170(mec-6)|WBGene00006748(unc-8)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003170(mec-6), WBGene00006748(unc-8)
Availability: available
Source References: PMID:7539392
Synonyms: dpy-5(e61) mec-6(lb84) I; unc-8(n491) IV.
Alternate IDs: WB-STRAIN:MP84, CGC_MP84
Notes: Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00026620 Copy
http://www.wormbase.org/db/get?name=WBStrain00026625
Source Database: WormBase (WB)
Affected Genes: WBGene00001170(egl-1)|WBGene00006345(sup-40)|WBGene00006748(unc-8)
Genomic Alteration: WBGene00001170(egl-1), WBGene00006345(sup-40), WBGene00006748(unc-8)
Availability: available
Source References: PMID:7539392
Synonyms: sup-40(lb130)/+ I; unc-8(e15) IV; egl-1(n487) V.
Alternate IDs: WB-STRAIN:MP130, CGC_MP130
Notes: lb130/+ dominantly suppresses the e15 backing defect and causes recessive sterility. Three phenotypes are present in this strain: backing steriles (lb130 homozygotes), backing fertiles which are bloated (heterozygotes), and non-backing coiled Unc animals which are fertile and bloated (sup-40(+)). Maintain strain by picking fertile animals which can back. egl-1(n487) is included in the strain to facilitate identification of lb130 homozygotes, which grow slowly; their sterility contrasts with the bloating of lb130/+ heterozygotes.
Proper citation: RRID:WB-STRAIN:WBStrain00026625 Copy
http://www.wormbase.org/db/get?name=WBStrain00026624
Source Database: WormBase (WB)
Affected Genes: WBGene00000950(deg-1)|WBGene00006346(sup-41)|WBGene00006748(unc-8)
Genomic Alteration: WBGene00000950(deg-1), WBGene00006346(sup-41), WBGene00006748(unc-8)
Availability: available
Source References: PMID:7539392
Synonyms: unc-8(n491) sup-41(lb125) IV; deg-1(u38) X.
Alternate IDs: WB-STRAIN:MP125, CGC_MP125
Notes: Animals move sluggishly but are able to back, despite n491. lb125 also partially suppresses the tail touch insensitive phenotype of u38 in cold-sensitive fashion: at 25C -> 0%; at 20C -> 5%; at 15C -> 30%.
Proper citation: RRID:WB-STRAIN:WBStrain00026624 Copy
http://www.wormbase.org/db/get?name=WBStrain00026623
Source Database: WormBase (WB)
Affected Genes: WBGene00006748(unc-8)
Genomic Alteration: WBGene00006748(unc-8)
Availability: available
Source References: PMID:7539392
Synonyms: unc-8(lb109) IV.
Alternate IDs: WB-STRAIN:MP109, CGC_MP109
Notes: Coils. Backs fairly well. The coiling phenotype is semi-dominant.
Proper citation: RRID:WB-STRAIN:WBStrain00026623 Copy
http://www.wormbase.org/db/get?name=WBStrain00026618
Source Database: WormBase (WB)
Affected Genes: WBGene00004092(ppt-1)
Genomic Alteration: WBGene00004092(ppt-1)
Availability: available
Synonyms: ppt-1(gk139) V.
Alternate IDs: WB-STRAIN:MN1, CGC_MN1
Notes: Delay in L4 to adult transition. Abnormal mitochondrial morphology.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00026618 Copy
http://www.wormbase.org/db/get?name=WBStrain00026610
Source Database: WormBase (WB)
Affected Genes: WBGene00016977(akap-1)
Genomic Alteration: WBGene00016977(akap-1)
Availability: available
Synonyms: akap-1(luc37) III.
Alternate IDs: WB-STRAIN:MLC657, CGC_MLC657
Notes: luc37 removes mir-791 binding sites in the akap-1 3'UTR. luc37 worms show less response towards a gradual increase in CO2 concentration from 0-5% as compared to N2 animals, similar to the response of mir-791(lf) animals. Reference: Drexel T, et al. Genes Dev. 2016 Sep 15;30(18):2042-2047.
Proper citation: RRID:WB-STRAIN:WBStrain00026610 Copy
http://www.wormbase.org/db/get?name=WBStrain00026695
Source Database: WormBase (WB)
Affected Genes: WBGene00001076(dpy-17)|WBGene00003559(ncl-1)|WBGene00006772(unc-36)
Genomic Alteration: WBGene00001076(dpy-17), WBGene00003559(ncl-1), WBGene00006772(unc-36)
Availability: available
Synonyms: dpy-17(e164) ncl-1(e1865) unc-36(e251) III; irDp1 (III;f).
Alternate IDs: WB-STRAIN:MS231, CGC_MS231
Notes: Mutagen:spontaneous|"Superficially WT. Pick WT to propagate. Throws WT (expressing unc-119::YFP) and DpyUncs. irDp1 is sDp3 carrying a spontaneous integrant of an array carrying unc-119::YFP + unc-32(+) + med-1(+), originally generated in BC4638. irDp1 appears to complement everything sDp3 does and has a similar meiotic transmission frequency of 60%. In another strain, irDp2 was observed to lose ability to complement dpy-17. irDp1 confers a progressive adult egg laying defect (also seen with sDp3)."
Proper citation: RRID:WB-STRAIN:WBStrain00026695 Copy
http://www.wormbase.org/db/get?name=WBStrain00026613
Source Database: WormBase (WB)
Affected Genes: WBGene00015349(henn-1)
Genomic Alteration: WBGene00015349(henn-1)
Availability: available
Synonyms: lucSi61 II; henn-1(tm4477) III.
Alternate IDs: WB-STRAIN:MLC749, CGC_MLC749
Notes: lucSi61 [ASEp::HEN1::unc-54 3UTR + Cbr-unc-119(+)] II. Superficially wild-type. Cell-type-specific 3'-terminal 2'-O-methylation of animal miRNAs by a genetically encoded plant-specific methyltransferase (Arabidopsis thaliana HEN1). NOTE: This strain might still carry unc-119(ed3) in the background. Reference: Alberti C, et al. Nat Methods. 2018 Feb 26. doi: 10.1038/nmeth.4610.|"Made_by: Chiara Alberti"|"No mutagen used"
Proper citation: RRID:WB-STRAIN:WBStrain00026613 Copy
http://www.wormbase.org/db/get?name=WBStrain00026611
Source Database: WormBase (WB)
Affected Genes: WBGene00015349(henn-1)
Genomic Alteration: WBGene00015349(henn-1)
Availability: available
Synonyms: lucSi40 II; henn-1(tm4477) III.
Alternate IDs: WB-STRAIN:MLC664, CGC_MLC664
Notes: lucSi40 [rgef-1p::HEN1::unc-54 3UTR + Cbr-unc-119(+)] II. Superficially wild-type. Cell-type-specific 3'-terminal 2'-O-methylation of animal miRNAs by a genetically encoded plant-specific methyltransferase (Arabidopsis thaliana HEN1). NOTE: This strain might still carry unc-119(ed3) in the background. Reference: Alberti C, et al. Nat Methods. 2018 Feb 26. doi: 10.1038/nmeth.4610.|"Made_by: Chiara Alberti"|"No mutagen used"
Proper citation: RRID:WB-STRAIN:WBStrain00026611 Copy
http://www.wormbase.org/db/get?name=WBStrain00026699
Source Database: WormBase (WB)
Affected Genes: WBGene00013583(ceh-51)
Genomic Alteration: WBGene00013583(ceh-51)
Availability: available
Source References: PMID:37611097
Synonyms: ceh-51(tm2123) V; irEx540.
Alternate IDs: WB-STRAIN:MS1206, CGC_MS1206
Notes: irEx540 is [unc-119::CFP (pMM809) + rol-6D (pRF4) + ceh-51(+)]. Throws arrested ceh-51(-) larvae, rescued animals expressing unc-119::CFP, and some unc-119::CFP-expressing larvae that are not rescued. Heterozygous mutant strain originally obtained from Shohei Mitani.|"irEx540 [ceh-51(+) + unc-119::CFP + rol-6(su1006)]. Throws arrested ceh-51(-) larvae, rescued animals expressing unc-119::CFP, and some unc-119::CFP-expressing larvae that are not rescued. Heterozygous mutant strain originally obtained from Shohei Mitani."|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00026699 Copy
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