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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140404
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals (as of 2021-04-29)
Alternate IDs: 4140404
Notes: Dr. Susumu Makino and his colleagues found several animals that had gait abnormalities among Wistar rats maintained at Shionogi Co. They named these animals osteogenic disorder (OD) rats because they exhibited prominent bone and joint abnormalities and systemic bleeding. Subsequent studies revealed that these symptoms were derived from an ascorbic acid (vitamin C) deficiency arising from defective gulonolactone oxidase (GLO) activity. This characteristic was confirmed to be the result of a mutation involving the autosomal single recessive gene od. Scurvy due to L-gulonolactone oxidase deficincy; phenotype normalizes if supplied with ascorbic acid 300mg/kg/d. od/od rats are more susceptible to dental caries as compared with +/+ rats, in only amoun parous females. CLEA Japan, Inc
Proper citation: RRID:RGD_4140404 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140409
Source Database: Rat Genome Database (RGD)
Genetic Background: consomic
Availability: Unknown
Alternate IDs: 4140409
Notes: Transfer of the DA-rat chromosome 16 (RNO16) into the COP-rat background
Proper citation: RRID:RGD_4140409 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140408
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Cryopreserved Embryo
Alternate IDs: 4140408
Notes: The LEXF/FXLE RI strain set has been established by Shisa et al at Saitama Cancer Center Research Institute since 1985. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4140408 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4891165
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 4891165
Notes: These are congenic wiggling rats established by transferring the wiggling gene from Long-Evans Cinnamon (LEC) to Wistar King-Aptekman/Hokkaido (WKAH) strain
Proper citation: RRID:RGD_4891165 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142540
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Sperm
Alternate IDs: 4142540
Notes: This congenic strain was established by crossing between WKY/Izm and SHR/Izm in 2001. Heterozygous consomic rats were established in 2004, homozygous consomic rats were established in 2005, and homozygous congenic rats were established by crossing among consomic heterozygous rats in 2009. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142540 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2325754
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: 2325754
Notes: Autosomal dominant mutation that arose spontaneously in SD rats. Genomic DNA analysis from mutants revealed a single base(G) insertion in the exon generating a novel 5' donor splice site. This led to the internal a 602-bp deletion of Pax6 mRNA.
Proper citation: RRID:RGD_2325754 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4145374
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 4145374
Notes: Congenic strain developed by crossing ACI.FHH-(D1Rat74-D1Rat90)/Eur (Rf-1a) males to ACI.FHH-(D1Mit18-D1Rat90)(D14Mit11-D14Rat33)(D14Rat65-D14Rat90)/EurMcwi (Rf-1a+4) double congenic females
Proper citation: RRID:RGD_4145374 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142545
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Sperm
Alternate IDs: 4142545
Notes: This congenic strain was established by crossing between WKY/Izm and SHR/Izm in 2001. Heterozygous consomic rats were established in 2004, homozygous consomic rats were established in 2005, and homozygous congenic rats were established by crossing among consomic heterozygous rats in 2009. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142545 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142546
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Cryopreserved Embryo
Alternate IDs: 4142546
Notes: Rats which showed a dental mutation such as morphological abnormalities of the teeth were found in the SHR-SP rats at Daiichi Seiyaku, Co., Ltd. in 1981. Transferred to Tokushima University in 2003. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142546 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142541
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: 4142541
Notes: This transgenic strain was generated by microinjection into fertilized oocytes of Wistar rats. The vector containing the Tek/GFP plasmid (pSP14/15.t2hgfpPan5) was a gift from Dr. TN Sato of University of Texas Southwestern Medical Center at Dallas. The transgene was excised from the plasmid vector by Sal I digestion. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142541 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142543
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: 4142543
Notes: The Gluco13 region, one of the significant QTL for glucose intolerance of SDT/Jcl was transferred onto the genetic background of BN/Seac strain. Established by speed congenic method since 2003 and afterwards maintained by sib mating (N6F11, July 2010). Please refer to STD.BN-Gluco13/Nyo. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142543 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142544
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Cryopreserved Embryo (as of 2024-09-24)
Alternate IDs: 4142544
Notes: A WKY rat showing higher serum adiponectin concentration was found in Department of Pathology, Kinki University School of Medicine. In 1974, this strain was transferred from Dr. Okamoto to Kyoto University. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142544 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142550
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Cryopreserved Sperm
Alternate IDs: 4142550
Notes: This congenic strain was established by crossing between WKY/Izm and SHR/Izm in 2001. Heterozygous consomic rats were established in 2004, homozygous consomic rats were established in 2005, and homozygous congenic rats were established by crossing among consomic heterozygous rats in 2009. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4142550 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4142799
Source Database: Rat Genome Database (RGD)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: 4142799
Notes: LEW/Crlc and SS/Jr were backcrossed for 5 generations, then BC5 rat was mated with SS/Jr to produce the desired congenic strain
Proper citation: RRID:RGD_4142799 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140413
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Cryopreserved Embryo
Alternate IDs: 4140413
Notes: The LEXF/FXLE RI strain set has been established by Shisa et al at Saitama Cancer Center Research Institute since 1985. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4140413 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5131920
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct
Alternate IDs: 5131920
Notes: This strain was produced by injecting ZFNs targeting the sequence CAGGCCCTGAACCGCttctggGATTACCTGCGCTGGG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 24-bp frameshift deletion in exon 2.
Proper citation: RRID:RGD_5131920 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5131921
Source Database: Rat Genome Database (RGD)
Genetic Background: mutant
Availability: Extinct
Alternate IDs: 5131921
Notes: This strain was produced by injecting ZFNs targeting the sequence CAGGCCCTGAACCGCttctggGATTACCTGCGCTGGG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 15-bp frameshift deletion in exon 2.
Proper citation: RRID:RGD_5131921 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5131122
Source Database: Rat Genome Database (RGD)
Genetic Background: recombinant_inbred
Availability: Unknown
Alternate IDs: 5131122
Notes: Embryo-rederived from breeder stock provided by Pravenec and Kren from the Prague colonies, maintained for over 20 generations and verified by PLS phenotyping and microsatellite genotyping.
Proper citation: RRID:RGD_5131122 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2325145
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 2325145
Notes: These were obtained from Charles River and maintained at University of Toledo, College of Medicine (Medical College of Ohio), Toledo, Ohio.
Proper citation: RRID:RGD_2325145 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2325143
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 2325143
Notes: SHR strain obtained from Harlan Sprague-Dawley (Indianapolis, IN) and maintained at University of Toledo, College of Medicine (Medical College of Ohio), Toledo, Ohio.
Proper citation: RRID:RGD_2325143 Copy
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