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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-a2-his.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|targeted mutation 1; University of Cologne|unknown|transgene insertion 1; Beatrice Perarnau
Availability: live
Synonyms: C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn> Tg(HLA-A/H2-D/B2M)1Bpe/Geno
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin; coisogenic strain|mutant strain: Rag2|Flt3|Il2rg|Sirpa|H2-D|HLA-A2.1|B2m
Proper citation: RRID:IMSR_BRGSF-A2 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=37
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Synonyms: C57BL/6 - lpr. B6-Tnfrsf6<lpr>/Orl
Alternate IDs: SCR_006136
Notes: gene symbol note: Fas cell surface death receptor; congenic strain: Fas
Proper citation: RRID:IMSR_EM:00037 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=30
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Christophe Benoist and Diane Mathis|targeted mutation 1; University of North Carolina
Availability: embryo
Synonyms: B6.Cg-B2m<tm1Unc>H2-Ab1<tm1Doi>/DoiOrl. beta2m<0>. Abeta<0>(MHC). B6.129-B2m<tm1Unc> H2-Ab1<tm1Doi>/DoiOrl
Alternate IDs: SCR_006136
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin; mutant strain: H2-Ab1|B2m
Proper citation: RRID:IMSR_EM:00030 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=64
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: transgene insertion e19h; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion e19h; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: PrPC-KO. E1931. B6;129S7-Prnp<tm1Cwe> Tg(Prnp)e19hCwe/CweIbcm. B6;129S7 Prnp<tm1Cwe>-Tg(Prnp)e19hCwe/Cwe. E1931-Tg. STOCK Prnp<tm1Cwe> Tg(Prnp)E1931Cwe
Alternate IDs: SCR_006136
Notes: gene symbol note: transgene insertion e19h; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)e19hCwe|Prnp
Proper citation: RRID:IMSR_EM:00064 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=56
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion d11; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion d11; Charles Weissmann
Availability: embryo
Synonyms: STOCK Prnp<tm1Cwe> Tg(Prnp)D11Cwe. B6;129S7-Prnp<tm1Cwe> Tg(Prnp)d11Cwe/CweIbcm. B6;129S7 Prnp<tm1Cwe>-Tg(Prnp)d11Cwe/Cwe. PrPC-KO. D11
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion d11; Charles Weissmann; mutant strain: Prnp|Tg(Prnp)d11Cwe
Proper citation: RRID:IMSR_EM:00056 Copy
Issue Issue
https://www.envigo.com/model/b6-129-rag2tm1fwaii2rgtm1rsky-dwlhsd
Source Database: Envigo an Inotiv Company
Affected Genes: recombination activating gene 2|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; University of Cologne
Availability: live
Synonyms: B6;129-Rag2<tm1Fwa> II2rg<tm1Cgn>/DwlHsd
Notes: gene symbol note: recombination activating gene 2|interleukin 2 receptor; gamma chain; mutant strain|inbred strain: Rag2|Il2rg
Proper citation: RRID:IMSR_ENV:HSD-021 Copy
Issue
The record is no longer available at this source.
Source Database: National Cancer Institute at Frederick
Affected Genes: Kirsten rat sarcoma viral oncogene homolog
Genomic Alteration: targeted mutation 4; Tyler Jacks
Availability: embryo
Notes: gene symbol note: Kirsten rat sarcoma viral oncogene homolog; congenic strain: Kras
Proper citation: RRID:IMSR_NCIMR:01XJ6 Copy
Issue
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41278
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: chemically induced mutation
Affected Genes: |Lyn|
Alternate IDs: MMRRC_41278-UCD, MMRRC_041278, MMRRC_41278
Notes: Research areas: Immunology and Inflammation; Mutation Type: chemically induced mutation ; Collection: NHMRC Australian PhenomeBank
Proper citation: RRID:MMRRC_041278-UCD Copy
Issue
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=42049
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Targeted Mutation
Affected Genes: |Apoe|App|
Alternate IDs: MMRRC_42049-JAX, MMRRC_042049, MMRRC_4249
Notes: Research areas: Cardiovascular, Diabetes, Immunology and Inflammation, Models for Human Disease, Obesity; Mutation Type: Targeted Mutation ; Collection:
Proper citation: RRID:MMRRC_042049-JAX Copy
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