Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
B6;129S7-Prnptm1Cwe Tg(Igh-15B3Vh/Ighm*a)502Zbz/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:02154 | Mus musculus | B6129-Prnp<tm1Cwe> Tg(15B3)502/Cnrm. TgN(15B3)502. Prnpo/o-15B3mu | gene symbol note: transgene insertion 502; Universitatsspital Zurich; Biologisches Zentrallaboratorium|prion protein; mutant strain: Tg(Igh-15B3Vh/Ighm*a)502Zbz|Prnp | transgene insertion 502; Universitatsspital Zurich; Biologisches Zentrallaboratorium|prion protein | transgene insertion 502; Universitatsspital Zurich; Biologisches Zentrallaboratorium|targeted mutation 1; Charles Weissmann | EM:02154 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:49:59 | 0 | |||
|
B10ScSn.BXSB-(D1Mit3-D1Mit235) Chr YBXSB/MpJ/BjmjrH Resource Report Resource Website Issue |
RRID:IMSR_EM:02280 | Mus musculus | B10.Yaa.Bxs4(20-48) | gene symbol note: accelerated autoimmunity and lymphoproliferation transposition; mutant strain: Yaa | accelerated autoimmunity and lymphoproliferation transposition | accelerated autoimmunity and lymphoproliferation | EM:02280 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:00 | 0 | |||
|
B10ScSn.BXSB-(D1Mit235-D1Mit1000) Chr YBXSB/MpJ/BjmjrH Resource Report Resource Website Issue |
RRID:IMSR_EM:02278 | Mus musculus | gene symbol note: accelerated autoimmunity and lymphoproliferation transposition; mutant strain: Yaa | accelerated autoimmunity and lymphoproliferation transposition | accelerated autoimmunity and lymphoproliferation | EM:02278 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:00 | 0 | ||||
|
B10ScSn.BXSB-(D1Mit123-D1Mit1000) Chr YBXSB/MpJ/BjmjrH Resource Report Resource Website Issue |
RRID:IMSR_EM:02279 | Mus musculus | B10.Yaa.Bxs1.4(40-67) | gene symbol note: accelerated autoimmunity and lymphoproliferation transposition; mutant strain: Yaa | accelerated autoimmunity and lymphoproliferation transposition | accelerated autoimmunity and lymphoproliferation | EM:02279 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:00 | 0 | |||
|
B10ScSn.BXSB-(D1Mit33-D1Mit223) Chr YBXSB/MpJ/BjmjrH Resource Report Resource Website Issue |
RRID:IMSR_EM:02276 | Mus musculus | B10.Yaa.Bxs3(160-190) | gene symbol note: accelerated autoimmunity and lymphoproliferation transposition; mutant strain: Yaa | accelerated autoimmunity and lymphoproliferation transposition | accelerated autoimmunity and lymphoproliferation | EM:02276 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:00 | 0 | |||
|
B10ScSn.BXSB-(D1Mit303-D1Mit305) Chr YBXSB/MpJ/BjmjrH Resource Report Resource Website Issue |
RRID:IMSR_EM:02277 | Mus musculus | B10.Yaa.Bxs1(63-89) | gene symbol note: accelerated autoimmunity and lymphoproliferation transposition; mutant strain: Yaa | accelerated autoimmunity and lymphoproliferation transposition | accelerated autoimmunity and lymphoproliferation | EM:02277 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:00 | 0 | |||
|
C3H101H-Pax3Sp-2H/H Resource Report Resource Website Issue |
RRID:IMSR_EM:02535 | Mus musculus | gene symbol note: paired box 3; mutant strain: Pax3 | paired box 3 | splotch 2 Harwell | EM:02535 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:03 | 0 | ||||
|
B6.129S-Tnftm1Gkl/Flmg Resource Report Resource Website Issue |
RRID:IMSR_EM:04790 | Mus musculus | Tnfalpha-/- | gene symbol note: tumor necrosis factor; mutant strain: Tnf | tumor necrosis factor | targeted mutation 1; George Kollias | EM:04790 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:07 | 0 | |||
|
B6JOlaHsd.Cg-Cdkn2atm1Rdp/Cnbc Resource Report Resource Website 1+ mentions Issue |
RRID:IMSR_EM:04766 | Mus musculus | Ink4a-Arf (-/-) null KO mice (P16 KO). Tyrp1<+>. B6.Cg-Cdkn2a<tm1Rdp>/SrnCnbc | gene symbol note: cyclin dependent kinase inhibitor 2A; mutant strain: Cdkn2a | cyclin dependent kinase inhibitor 2A | targeted mutation 1; Ronald DePinho | EM:04766 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:07 | 2 | |||
|
STOCK Cdkn2atm1Rdp Tg(Cnp-TVA.-lacZ)B8Ubc/Kctt Resource Report Resource Website Issue |
RRID:IMSR_EM:04997 | Mus musculus | Ctv-a Ink4a-Arf-/- | gene symbol note: cyclin dependent kinase inhibitor 2A|transgene insertion B8; Uppsala University; mutant strain: Cdkn2a|Tg(Cnp-TVA;-lacZ)B8Ubc | cyclin dependent kinase inhibitor 2A|transgene insertion B8; Uppsala University | targeted mutation 1; Ronald DePinho|transgene insertion B8; Uppsala University | EM:04997 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:08 | 0 | |||
|
C.Cg-Tg(Tek-cre)1Ywa/Cnbc Resource Report Resource Website Issue |
RRID:IMSR_EM:05243 | Mus musculus | Tie2 Cre Balb/c (backcross of Cg-Tg(Tek-cre)1Ywa/J - Jax). C.Cg-Tg(Tek-cre)1Ywa/JCnbc | gene symbol note: transgene insertion 1; Masashi Yanagisawa; mutant strain: Tg(Tek-cre)1Ywa | transgene insertion 1; Masashi Yanagisawa | transgene insertion 1; Masashi Yanagisawa | EM:05243 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:09 | 0 | |||
|
STOCK B2mtm1Unc H2-Ab1 Resource Report Resource Website Issue |
RRID:IMSR_EM:05922 | Mus musculus | gene symbol note: transgene insertion 1; Beatrice Perarnau|beta-2 microglobulin|transgene insertion 1; Daniel M Altmann|histocompatibility 2; class II antigen A; beta 1|Tg(Cd4-EGFP); mutant strain: Tg(HLA-A/H2-D/B2M)1Bpe|B2m|Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|H2-Ab1|Tg(Cd4-EGFP) | transgene insertion 1; Beatrice Perarnau|beta-2 microglobulin|transgene insertion 1; Daniel M Altmann|histocompatibility 2; class II antigen A; beta 1|Tg(Cd4-EGFP) | transgene insertion 1; Beatrice Perarnau|targeted mutation 1; University of North Carolina|transgene insertion 1; Daniel M Altmann|targeted mutation 1; Christophe Benoist and Diane Mathis|Tg(Cd4-EGFP) | EM:05922 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | archived | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:14 | 0 | ||||
|
STOCK Prnptm1Cwe Tg(Prnp)E1Rchi/Cnrm Resource Report Resource Website 1+ mentions Issue Issue |
RRID:IMSR_EM:06141 | Mus musculus | Tg(WT-E1)/Prnp0/0 | gene symbol note: transgene insertion E1; Roberto Chiesa|prion protein; mutant strain: Tg(Prnp)E1Rchi|Prnp | transgene insertion E1; Roberto Chiesa|prion protein | transgene insertion E1; Roberto Chiesa|targeted mutation 1; Charles Weissmann | EM:06141 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:16 | 1 | |||
|
B6.Cg-Prnptm1Cwe Tg(Prnp)E1Rchi/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:06143 | Mus musculus | gene symbol note: transgene insertion E1; Roberto Chiesa|prion protein; mutant strain: Tg(Prnp)E1Rchi|Prnp | transgene insertion E1; Roberto Chiesa|prion protein | transgene insertion E1; Roberto Chiesa|targeted mutation 1; Charles Weissmann | EM:06143 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:16 | 0 | ||||
|
STOCK Prnptm1Cwe Tg(Prnp*D177N*M128V)G1Rchi/Cnrm Resource Report Resource Website Issue Issue |
RRID:IMSR_EM:06144 | Mus musculus | Tg(CJD-G1)/Prnp0/0 | gene symbol note: prion protein|transgene insertion G1; Roberto Chiesa; mutant strain: Prnp|Tg(Prnp*D177N*M128V)G1Rchi | prion protein|transgene insertion G1; Roberto Chiesa | targeted mutation 1; Charles Weissmann|transgene insertion G1; Roberto Chiesa | EM:06144 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:16 | 0 | |||
|
STOCK Rag2tm1Fwa B2m Resource Report Resource Website Issue Issue Issue |
RRID:IMSR_EM:06327 | Mus musculus | SURE-L1/Rag2°/°GammaC°/°Prf°/°. STOCK Rag2<tm1Fwa> B2m<tm1Unc> Prf1<tm1Sdz> H2-Ab1<tm1Doi> Il2rg<tm1Sug> Tg(HLA-A/H2-D/B2M)1Bpe Tg(HLA-DRA*0101.HLA-DRB1*0101)1Dma/Orl. HUMAMICE | gene symbol note: transgene insertion 1; Beatrice Perarnau|perforin 1 (pore forming protein)|beta-2 microglobulin|recombination activating gene 2|interleukin 2 receptor; gamma chain|transgene insertion 1; Daniel M Altmann|histocompatibility 2; class II antigen A; beta 1; mutant strain: Tg(HLA-A/H2-D/B2M)1Bpe|Prf1|B2m|Rag2|Il2rg|Tg(HLA-DRA*0101;HLA-DRB1*0101)1Dma|H2-Ab1 | transgene insertion 1; Beatrice Perarnau|perforin 1 (pore forming protein)|beta-2 microglobulin|recombination activating gene 2|interleukin 2 receptor; gamma chain|transgene insertion 1; Daniel M Altmann|histocompatibility 2; class II antigen A; beta 1 | transgene insertion 1; Beatrice Perarnau|targeted mutation 1; Sandoz Pharmaceuticals|targeted mutation 1; University of North Carolina|targeted mutation 1; Frederick W Alt|targeted mutation 1; Kazuo Sugamura|transgene insertion 1; Daniel M Altmann|targeted mutation 1; Christophe Benoist and Diane Mathis | EM:06327 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | embryo | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:17 | 0 | |||
|
MRL.Cg-Ccr1tm1Gao Fas Resource Report Resource Website Issue |
RRID:IMSR_EM:08422 | Mus musculus | `. MRL.129S4(B6)-Ccr1tm1Gao Faslpr/Cnbc. 1L-M | gene symbol note: C-C motif chemokine receptor 1|Fas cell surface death receptor; mutant strain: Ccr1|Fas | C-C motif chemokine receptor 1|Fas cell surface death receptor | targeted mutation 1; Ji-Liang Gao|lymphoproliferation | EM:08422 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:29 | 0 | |||
|
MRL.Cg-Ccr5tm1Blck Fas Resource Report Resource Website Issue |
RRID:IMSR_EM:08424 | Mus musculus | 5-LM | gene symbol note: C-C motif chemokine receptor 5|Fas cell surface death receptor; mutant strain: Ccr5|Fas | C-C motif chemokine receptor 5|Fas cell surface death receptor | targeted mutation 1; Bruno Luckow|lymphoproliferation | EM:08424 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:29 | 0 | |||
|
MRL.Cg-Ccr2tm1Blck Fas Resource Report Resource Website Issue |
RRID:IMSR_EM:08423 | Mus musculus | 2L-M | gene symbol note: Fas cell surface death receptor|C-C motif chemokine receptor 2; mutant strain: Fas|Ccr2 | Fas cell surface death receptor|C-C motif chemokine receptor 2 | lymphoproliferation|targeted mutation 1; Bruno Luckow | EM:08423 | European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA) | EMMA | sperm | SCR_006136 | International Mouse Resource Center | 2026-10-23 11:50:29 | 0 | |||
|
NOD.Cg-Cd28tm1Mak Cd40tm1Kik Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037143-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| decreased bone mineral density [MP:0000063]| decreased neutrophil cell number [MP:0000222]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal humoral immune response [MP:0001800]| decreased IgA level [MP:0001807]| no abnormal phenotype detected [MP:0002169]| abnormal thymus medulla morphology [MP:0002375]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| decreased IgE level [MP:0002492]| glomerulonephritis [MP:0002743]| increased urine protein level [MP:0002962]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]| decreased cerebral infarction size [MP:0006058]| increased follicular B cell number [MP:0008173]| absent germinal center B cells [MP:0008179]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| abnormal B cell activation [MP:0008217]| absent spleen germinal center [MP:0008474]| decreased IgG1 level [MP:0008495]| decreased IgG2a level [MP:0008496]| decreased IgG2b level [MP:0008497]| decreased IgG3 level [MP:0008498]| abnormal thymus epithelium morphology [MP:0009544]| decreased platelet aggregation [MP:0009549]| decreased trabecular bone mass [MP:0010873]| decreased compact bone mass [MP:0010962]| renal glomerular immunoglobulin deposits [MP:0020519]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| abnormal esophageal epithelium morphology [MP:0000468]| enlarged thymus [MP:0000709]| increased activated T cell number [MP:0001829]| brain inflammation [MP:0001847]| increased T cell derived lymphoma incidence [MP:0002024]| abnormal T cell differentiation [MP:0002145]| abnormal lymphopoiesis [MP:0002401]| decreased immunoglobulin level [MP:0002460]| abnormal cytokine secretion [MP:0003009]| esophageal inflammation [MP:0003278]| insulitis [MP:0004031]| increased length of allograft survival [MP:0004751]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| abnormal class switch recombination [MP:0004816]| abnormal regulatory T cell physiology [MP:0004946]| decreased regulatory T cell number [MP:0004974]| abnormal T cell clonal deletion [MP:0005002]| increased eosinophil cell number [MP:0005011]| increased susceptibility to parasitic infection [MP:0005027]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased cytotoxic T cell cytolysis [MP:0005079]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005465]| abnormal T-helper 1 physiology [MP:0005466]| abnormal T-helper 2 physiology [MP:0005596]| increased susceptibility to type I hypersensitivity reaction [MP:0005671]| abnormal response to transplant [MP:0006413]| increased T cell apoptosis [MP:0008049]| increased memory T cell number [MP:0008074]| increased CD4-positive [MP:0008078]| alpha beta T cell number [MP:0008192]| increased CD8-positive [MP:0008482]| alpha-beta T cell number [MP:0008495]| abnormal germinal center B cell physiology [MP:0008496]| decreased spleen germinal center number [MP:0008497]| decreased IgG1 level [MP:0008500]| decreased IgG2a level [MP:0008566]| decreased IgG2b level [MP:0008567]| increased IgG2a level [MP:0008578]| increased interferon-gamma secretion [MP:0008603]| decreased interferon-gamma secretion [MP:0008687]| decreased circulating interferon-gamma level [MP:0008688]| decreased circulating interleukin-4 level [MP:0008699]| increased interleukin-2 secretion [MP:0008700]| decreased interleukin-2 secretion [MP:0008747]| increased interleukin-4 secretion [MP:0009335]| decreased interleukin-4 secretion [MP:0010268]| abnormal T cell anergy [MP:0010766] | Cd28||Ifng||Cd40||| | 037143-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37143-MU, MMRRC_037143, MMRRC_37143 | MMRRC | 2026-10-24 06:37:06 | 1 |
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