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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: DExH-box helicase 58
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Notes: gene symbol note: DExH-box helicase 58; mutant strain|congenic strain: Dhx58
Proper citation: RRID:IMSR_OBS:25 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: interferon induced with helicase C domain 1
Genomic Alteration: targeted mutation 1; Shizuro Akira
Availability: live
Notes: gene symbol note: interferon induced with helicase C domain 1; mutant strain|congenic strain: Ifih1
Proper citation: RRID:IMSR_OBS:23 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: RNA sensor RIG-I
Genomic Alteration: targeted mutation Shizuo Akira
Availability: live
Notes: gene symbol note: RNA sensor RIG-I; mutant strain|congenic strain: Rigi
Proper citation: RRID:IMSR_OBS:24 Copy
https://orientalbioservice.com/index.files/hrh_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: histamine receptor H1
Genomic Alteration: targeted mutation 1; Takeshi Watanabe
Availability: live
Synonyms: B6.129P2-Hrh1
Notes: gene symbol note: histamine receptor H1; mutant strain|congenic strain: Hrh1
Proper citation: RRID:IMSR_OBS:27 Copy
https://orientalbioservice.com/index.files/hrh_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: histamine receptor H1
Genomic Alteration: targeted mutation 1; Takeshi Watanabe
Availability: live
Synonyms: C.129P2(B6)-Hrh1
Notes: gene symbol note: histamine receptor H1; mutant strain|congenic strain: Hrh1
Proper citation: RRID:IMSR_OBS:28 Copy
Issue
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: apolipoprotein A-I|apolipoprotein E
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: live
Notes: gene symbol note: apolipoprotein A-I|apolipoprotein E; mutant strain|congenic strain: Apoa1|Apoe
Proper citation: RRID:IMSR_ARC:APOE Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/dt/pd-1-vista.htm
Source Database: genOway
Affected Genes: V-set immunoregulatory receptor|programmed cell death 1
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Synonyms: C57BL/6N-Pdcd1
Notes: gene symbol note: V-set immunoregulatory receptor|programmed cell death 1; coisogenic strain|mutant strain: Vsir|Pdcd1
Proper citation: RRID:IMSR_ICP56 Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/dt/pd-1-ctla-4.htm
Source Database: genOway
Affected Genes: programmed cell death 1|cytotoxic T-lymphocyte-associated protein 4
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Synonyms: C57BL/6N-Pdcd1
Notes: gene symbol note: programmed cell death 1|cytotoxic T-lymphocyte-associated protein 4; coisogenic strain|mutant strain: Pdcd1|Ctla4
Proper citation: RRID:IMSR_ICP45 Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: aryl-hydrocarbon receptor|forebrain weight 1|glucose homeostasis QTL 2|forebrain weight 2|nuclear encoded tRNA arginine 5 (anticodon TCT)|glucose homeostasis QTL 3|cadherin 23 (otocadherin)|glucose homeostasis QTL 1|microwave induced increase in complement receptor B cells|nicotinamide nucleotide transhydrogenase|purinergic receptor P2X; ligand-gated ion channel; 7
Genomic Alteration: b-1 variant|C57BL/6J|mutation 1; Jackson|age related hearing loss 1|non-responder|rs48804829 SNP allele with the T variant
Availability: live
Notes: gene symbol note: aryl-hydrocarbon receptor|forebrain weight 1|glucose homeostasis QTL 2|forebrain weight 2|nuclear encoded tRNA arginine 5 (anticodon TCT)|glucose homeostasis QTL 3|cadherin 23 (otocadherin)|glucose homeostasis QTL 1|microwave induced increase in complement receptor B cells|nicotinamide nucleotide transhydrogenase|purinergic receptor P2X; ligand-gated ion channel; 7; inbred strain: Ahr|Fbrwt1|Gluchos2|Fbrwt2|n-TRtct5|Gluchos3|Cdh23|Gluchos1|Micrl|Nnt|P2rx7
Proper citation: RRID:IMSR_ARC:B6 Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/st/hgitr.htm
Source Database: genOway
Affected Genes: tumor necrosis factor receptor superfamily; member 18
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Synonyms: C57BL/6N-Tnfrsf18
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 18; coisogenic strain|mutant strain: Tnfrsf18
Proper citation: RRID:IMSR_ICP18 Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/dt/pd-1-tim3.htm
Source Database: genOway
Affected Genes: hepatitis A virus cellular receptor 2|programmed cell death 1
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Notes: gene symbol note: hepatitis A virus cellular receptor 2|programmed cell death 1; coisogenic strain|mutant strain: Havcr2|Pdcd1
Proper citation: RRID:IMSR_ICP26 Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/st/hox40.htm
Source Database: genOway
Affected Genes: tumor necrosis factor receptor superfamily; member 4
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Synonyms: C57BL/6N-Tnfrsf4
Notes: gene symbol note: tumor necrosis factor receptor superfamily; member 4; coisogenic strain|mutant strain: Tnfrsf4
Proper citation: RRID:IMSR_ICP2 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-model.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|unknown|targeted mutation 1; University of Cologne
Availability: live
Synonyms: C.Cg-Rag2
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain; coisogenic strain|mutant strain: Rag2|Flt3|Sirpa|Il2rg
Proper citation: RRID:IMSR_BRGSF Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/st/hvista.htm
Source Database: genOway
Affected Genes: V-set immunoregulatory receptor
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Notes: gene symbol note: V-set immunoregulatory receptor; coisogenic strain|mutant strain: Vsir
Proper citation: RRID:IMSR_ICP3 Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: dysferlin
Genomic Alteration: progressive muscular dystrophy
Availability: live
Notes: gene symbol note: dysferlin; mutant strain|congenic strain: Dysf
Proper citation: RRID:IMSR_ARC:BLA Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr2
Notes: gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2
Proper citation: RRID:IMSR_OBS:9 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: myeloid differentiation primary response gene 88
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: MyD88 KO BALB/c. C.129P2-Myd88
Notes: gene symbol note: myeloid differentiation primary response gene 88; mutant strain|congenic strain: Myd88
Proper citation: RRID:IMSR_OBS:8 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-a2-his.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|targeted mutation 1; University of Cologne|unknown|transgene insertion 1; Beatrice Perarnau
Availability: live
Synonyms: C.Cg-Rag2
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin; coisogenic strain|mutant strain: Rag2|Flt3|Il2rg|Sirpa|H2-D|HLA-A2.1|B2m
Proper citation: RRID:IMSR_BRGSF-A2 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 4
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr4
Notes: gene symbol note: toll-like receptor 4; mutant strain|congenic strain: Tlr4
Proper citation: RRID:IMSR_OBS:10 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 7
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr7
Notes: gene symbol note: toll-like receptor 7; mutant strain|congenic strain: Tlr7
Proper citation: RRID:IMSR_OBS:11 Copy
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