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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.jax.org/strain/039144
Source Database: JAX Mice and Services
Affected Genes: |reverse tetracycline-controlled transactivator|collagen; type I; alpha 1|transformation related protein 53|gene trap ROSA 26; Philippe Soriano|Kras proto-oncogene; GTPase
Genomic Alteration: targeted mutation 2; Scott Lowe|targeted mutation 2; Tuomas Tammela|targeted mutation 1; Anton Berns|targeted mutation 4; Tyler Jacks
Availability: live
Synonyms: B6.Cg-Gt(ROSA)26Sor<tm2(CAG-rtTA3.-mKate2)Slowe> Kras<tm4Tyj> Trp53<tm1Brn> Col1a1<tm2(tetO-GFP/RNAi:Kras462)Ttam>/TtamJ
Notes: gene symbol note: |reverse tetracycline-controlled transactivator|collagen; type I; alpha 1|transformation related protein 53|gene trap ROSA 26; Philippe Soriano|Kras proto-oncogene; GTPase; mutant stock: |rtTA|Col1a1|Trp53|Gt(ROSA)26Sor|Kras
Proper citation: RRID:IMSR_JAX:039144 Copy
https://www.jax.org/strain/039526
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano
Genomic Alteration: endonuclease-mediated mutation 1; Sidi Chen
Availability: live
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano; coisogenic strain|mutant strain: Gt(ROSA)26Sor
Proper citation: RRID:IMSR_JAX:039526 Copy
https://www.jax.org/strain/039577
Source Database: JAX Mice and Services
Affected Genes: EYA transcriptional coactivator and phosphatase 2
Genomic Alteration: targeted mutation 2; Pin-Xian Xu
Availability: live
Notes: gene symbol note: EYA transcriptional coactivator and phosphatase 2; mutant stock: Eya2
Proper citation: RRID:IMSR_JAX:039577 Copy
https://www.jax.org/strain/039554
Source Database: JAX Mice and Services
Affected Genes: mab-21-like 2
Genomic Alteration: targeted mutation 1.1; King L Chow
Availability: live
Notes: gene symbol note: mab-21-like 2; mutant strain|congenic strain: Mab21l2
Proper citation: RRID:IMSR_JAX:039554 Copy
https://www.jax.org/strain/039319
Source Database: JAX Mice and Services
Affected Genes: immunoglobulin kappa chain complex|immunoglobulin heavy chain complex
Genomic Alteration: endonuclease-mediated mutation 4; Dan Rohrer|endonuclease-mediated mutation 2; Dan Rohrer|endonuclease-mediated mutation 1; Dan Rohrer
Availability: live
Notes: gene symbol note: immunoglobulin kappa chain complex|immunoglobulin heavy chain complex; mutant stock: Igk|Igh
Proper citation: RRID:IMSR_JAX:039319 Copy
https://www.jax.org/strain/039562
Source Database: JAX Mice and Services
Affected Genes: submaxillary gland androgen regulated protein 2
Genomic Alteration: targeted mutation 1; David D Ginty
Availability: live
Notes: gene symbol note: submaxillary gland androgen regulated protein 2; mutant stock: Smr2
Proper citation: RRID:IMSR_JAX:039562 Copy
https://www.jax.org/strain/039564
Source Database: JAX Mice and Services
Affected Genes: transient receptor potential cation channel; subfamily M; member 8
Genomic Alteration: targeted mutation 1; David D Ginty
Availability: live
Notes: gene symbol note: transient receptor potential cation channel; subfamily M; member 8; mutant stock: Trpm8
Proper citation: RRID:IMSR_JAX:039564 Copy
https://www.jax.org/strain/039496
Source Database: JAX Mice and Services
Affected Genes: interleukin 6|interleukin 2 receptor; gamma chain|FMS-like tyrosine kinase 3|protein kinase; DNA activated; catalytic polypeptide
Genomic Alteration: endonuclease-mediated mutation 1; Karolina Palucka|targeted mutation 1; Warren J Leonard|severe combined immunodeficiency
Availability: live
Synonyms: NSGF6
Notes: gene symbol note: interleukin 6|interleukin 2 receptor; gamma chain|FMS-like tyrosine kinase 3|protein kinase; DNA activated; catalytic polypeptide; mutant strain|congenic strain: Il6|Il2rg|Flt3|Prkdc
Proper citation: RRID:IMSR_JAX:039496 Copy
https://www.jax.org/strain/039888
Source Database: JAX Mice and Services
Affected Genes: DEAD box helicase 3; X-linked
Genomic Alteration: endonuclease-mediated mutation 1; Thirumala-Devi Kanneganti
Availability: live
Notes: gene symbol note: DEAD box helicase 3; X-linked; mutant strain: Ddx3x
Proper citation: RRID:IMSR_JAX:039888 Copy
https://www.jax.org/strain/039769
Source Database: JAX Mice and Services
Availability: live
Notes: gene symbol note: ; mutant strain|congenic strain:
Proper citation: RRID:IMSR_JAX:039769 Copy
https://www.jax.org/strain/039694
Source Database: JAX Mice and Services
Affected Genes: proteasome (prosome; macropain) subunit; beta type 1
Genomic Alteration: endonuclease-mediated mutation 1; Jackson
Availability: live
Notes: gene symbol note: proteasome (prosome; macropain) subunit; beta type 1; coisogenic strain|mutant strain: Psmb1
Proper citation: RRID:IMSR_JAX:039694 Copy
https://www.jax.org/strain/039795
Source Database: JAX Mice and Services
Affected Genes: parathyroid hormone-like peptide
Genomic Alteration: targeted mutation 1; Z Josh Huang
Availability: live
Synonyms: STOCK Pthlh<tm1.1(flpo)Zjh>/J
Notes: gene symbol note: parathyroid hormone-like peptide; mutant stock: Pthlh
Proper citation: RRID:IMSR_JAX:039795 Copy
https://www.jax.org/strain/039687
Source Database: JAX Mice and Services
Affected Genes: aquaporin 4
Genomic Alteration: endonuclease-mediated mutation 2; Joseph D Dougherty
Availability: live
Notes: gene symbol note: aquaporin 4; coisogenic strain|mutant strain: Aqp4
Proper citation: RRID:IMSR_JAX:039687 Copy
https://www.jax.org/strain/039849
Source Database: JAX Mice and Services
Affected Genes: activity-dependent neuroprotective protein
Genomic Alteration: endonuclease-mediated mutation 1; Pierre Mattar
Availability: live
Synonyms: B6J.B6N-Adnp<em1Pmtr>/J
Notes: gene symbol note: activity-dependent neuroprotective protein; inbred strain: Adnp
Proper citation: RRID:IMSR_JAX:039849 Copy
https://www.jax.org/strain/039775
Source Database: JAX Mice and Services
Affected Genes: apolipoprotein E|amyloid beta precursor protein
Genomic Alteration: targeted mutation 1.1; MODEL-AD Center|targeted mutation 1; Denali Therapeutics
Availability: live
Notes: gene symbol note: apolipoprotein E|amyloid beta precursor protein; mutant strain|congenic strain: APOE|Apoe|App
Proper citation: RRID:IMSR_JAX:039775 Copy
https://www.jax.org/strain/039935
Source Database: JAX Mice and Services
Affected Genes: piezo-type mechanosensitive ion channel component 2
Genomic Alteration: endonuclease-mediated mutation 1.1; David D Ginty
Availability: live
Notes: gene symbol note: piezo-type mechanosensitive ion channel component 2; mutant stock: Piezo2
Proper citation: RRID:IMSR_JAX:039935 Copy
https://www.jax.org/strain/039826
Source Database: JAX Mice and Services
Affected Genes: Fc receptor; IgG; high affinity I
Genomic Alteration: endonuclease-mediated mutation 1; Ming O Li
Availability: live
Notes: gene symbol note: Fc receptor; IgG; high affinity I; mutant strain: Fcgr1
Proper citation: RRID:IMSR_JAX:039826 Copy
https://www.jax.org/strain/039995
Source Database: JAX Mice and Services
Affected Genes: amyloid beta precursor protein|microtubule-associated protein tau|presenilin 1
Genomic Alteration: endonuclease-mediated mutation 5; Michael Sasner|endonuclease-mediated mutation 2; Cathy Lutz|endonuclease-mediated mutation 1; Michael Sasner
Availability: live
Notes: gene symbol note: amyloid beta precursor protein|microtubule-associated protein tau|presenilin 1; mutant strain|congenic strain: App|Mapt|Psen1
Proper citation: RRID:IMSR_JAX:039995 Copy
https://www.jax.org/strain/039996
Source Database: JAX Mice and Services
Affected Genes: presenilin 1|microtubule-associated protein tau|amyloid beta precursor protein|TAR DNA binding protein
Genomic Alteration: endonuclease-mediated mutation 1; Michael Sasner|endonuclease-mediated mutation 2; Cathy Lutz|endonuclease-mediated mutation 5; Michael Sasner|endonuclease-mediated mutation 9; Cathy Lutz
Availability: live
Notes: gene symbol note: presenilin 1|microtubule-associated protein tau|amyloid beta precursor protein|TAR DNA binding protein; mutant strain|congenic strain: Psen1|Mapt|App|Tardbp
Proper citation: RRID:IMSR_JAX:039996 Copy
https://www.jax.org/strain/040069
Source Database: JAX Mice and Services
Affected Genes: fibroblast activation protein
Genomic Alteration: endonuclease-mediated mutation 1; Nadia Rosenthal
Availability: live
Synonyms: C57BL/6J-Fap<em1Nros>/NrosJ
Notes: gene symbol note: fibroblast activation protein; coisogenic strain|mutant strain: Fap
Proper citation: RRID:IMSR_JAX:040069 Copy
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