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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062501
Source Database: WormBase (WB)
Affected Genes: WBGene00013285(dct-12)
Genomic Alteration: WBGene00013285(dct-12)
Availability: unknown
Source References: EMPTY
Synonyms: t10h9.1(yum2567) zc443.7(yum2568) y57a10c.10(yum2569) w05h5.1(yum2570) y57a10c.8(yum2571) f38h12.5(yum2572) y57a10c.9(yum2573) dct-12(yum2574) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062501 Copy
http://www.wormbase.org/db/get?name=WBStrain00062469
Source Database: WormBase (WB)
Affected Genes: WBGene00005638(srm-1)|WBGene00005639(srm-2)|WBGene00005640(srn-1)|WBGene00009808(srm-4)|WBGene00009810(srm-6)|WBGene00010273(srm-3)|WBGene00044112(srm-5)
Genomic Alteration: WBGene00005638(srm-1), WBGene00005639(srm-2), WBGene00005640(srn-1), WBGene00009808(srm-4), WBGene00009810(srm-6), WBGene00010273(srm-3), WBGene00044112(srm-5)
Availability: unknown
Source References: EMPTY
Synonyms: srm-1(yum2328) srm-2(yum2329) srm-3(yum2330) srm-4(yum2331) srm-5(yum2332) srm-6(yum2333) srn-1(yum2334) IV.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062469 Copy
http://www.wormbase.org/db/get?name=WBStrain00062502
Source Database: WormBase (WB)
Affected Genes: WBGene00005846(srw-99)|WBGene00005847(srw-100)|WBGene00005848(srw-101)|WBGene00005849(srw-102)|WBGene00005850(srw-103)|WBGene00005854(srw-107)|WBGene00005856(srw-109)
Genomic Alteration: WBGene00005846(srw-99), WBGene00005847(srw-100), WBGene00005848(srw-101), WBGene00005849(srw-102), WBGene00005850(srw-103), WBGene00005854(srw-107), WBGene00005856(srw-109)
Availability: unknown
Source References: EMPTY
Synonyms: srw-99(yum2575) srw-100(yum2576) srw-101(yum2577) srw-102(yum2578) srw-103(yum2579) srw-107(yum2580) srw-109(yum2581) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062502 Copy
http://www.wormbase.org/db/get?name=WBStrain00062451
Source Database: WormBase (WB)
Affected Genes: WBGene00011570(sre-28)|WBGene00012287(sre-33)|WBGene00012288(sre-32)|WBGene00013281(sre-27)|WBGene00013282(sre-26)|WBGene00016832(sre-49)
Genomic Alteration: WBGene00011570(sre-28), WBGene00012287(sre-33), WBGene00012288(sre-32), WBGene00013281(sre-27), WBGene00013282(sre-26), WBGene00016832(sre-49)
Availability: unknown
Source References: EMPTY
Synonyms: sre-26(yum2213) sre-27(yum2214) sre-28(yum2215) sre-32(yum2216) sre-33(yum2217) sre-49(yum2218) II.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062451 Copy
http://www.wormbase.org/db/get?name=WBStrain00062452
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: t27e7.9(yum1046) t27e7.4(yum1047) t27e7.5(yum1048) t27e7.3(yum1049) IV.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062452 Copy
http://www.wormbase.org/db/get?name=WBStrain00062455
Source Database: WormBase (WB)
Affected Genes: WBGene00014191(srt-22)|WBGene00015998(srt-59)|WBGene00016856(srt-15)|WBGene00016857(srt-16)|WBGene00018552(srt-19)|WBGene00018558(srt-20)|WBGene00018617(srt-17)|WBGene00019850(srt-18)|WBGene00021947(srt-23)|WBGene00021951(srt-24)
Genomic Alteration: WBGene00014191(srt-22), WBGene00015998(srt-59), WBGene00016856(srt-15), WBGene00016857(srt-16), WBGene00018552(srt-19), WBGene00018558(srt-20), WBGene00018617(srt-17), WBGene00019850(srt-18), WBGene00021947(srt-23), WBGene00021951(srt-24)
Availability: unknown
Source References: EMPTY
Synonyms: srt-19(yum2232) srt-20(yum2233) srt-22(yum2234) srt-15(yum2235) srt-16(yum2236) srt-17(yum2237) srt-18(yum2238) srt-23(yum2239) srt-24(yum2240) srt-59(yum2241) y55f3c.10(yum2242) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062455 Copy
http://www.wormbase.org/db/get?name=WBStrain00062456
Source Database: WormBase (WB)
Affected Genes: WBGene00007395(dcar-1)|WBGene00010329(pcdr-1)|WBGene00017779(gtr-1)
Genomic Alteration: WBGene00007395(dcar-1), WBGene00010329(pcdr-1), WBGene00017779(gtr-1)
Availability: unknown
Source References: EMPTY
Synonyms: dcar-1(yum2244) pcdr-1(yum2245) d2023.1(yum2246) gtr-1(yum2247) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062456 Copy
http://www.wormbase.org/db/get?name=WBStrain00062459
Source Database: WormBase (WB)
Affected Genes: WBGene00008982(srsx-2)|WBGene00009566(srsx-1)|WBGene00022404(srsx-5)|WBGene00022405(srsx-6)|WBGene00022406(srsx-7)|WBGene00022408(srsx-3)
Genomic Alteration: WBGene00008982(srsx-2), WBGene00009566(srsx-1), WBGene00022404(srsx-5), WBGene00022405(srsx-6), WBGene00022406(srsx-7), WBGene00022408(srsx-3)
Availability: unknown
Source References: EMPTY
Synonyms: srsx-1(yum2261) srsx-2(yum2262) srsx-3(yum2263) srsx-5(yum2264) srsx-6(yum2265) srsx-7(yum2266) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062459 Copy
http://www.wormbase.org/db/get?name=WBStrain00062440
Source Database: WormBase (WB)
Affected Genes: WBGene00005874(srw-127)|WBGene00005876(srw-129)|WBGene00005880(srw-133)|WBGene00005881(srw-134)|WBGene00005883(srw-136)|WBGene00005891(srw-144)|WBGene00011197(srw-145)
Genomic Alteration: WBGene00005874(srw-127), WBGene00005876(srw-129), WBGene00005880(srw-133), WBGene00005881(srw-134), WBGene00005883(srw-136), WBGene00005891(srw-144), WBGene00011197(srw-145)
Availability: unknown
Source References: EMPTY
Synonyms: srw-127(yum2144) srw-129(yum2145) srw-136(yum2146) srw-133(yum2147) srw-134(yum2148) srw-144(yum2149) srw-145(yum2150) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062440 Copy
http://www.wormbase.org/db/get?name=WBStrain00062445
Source Database: WormBase (WB)
Affected Genes: WBGene00005101(srd-23)|WBGene00005103(srd-25)|WBGene00005104(srd-26)|WBGene00005105(srd-27)|WBGene00005106(srd-28)|WBGene00005107(srd-29)|WBGene00005108(srd-30)|WBGene00005109(srd-31)
Genomic Alteration: WBGene00005101(srd-23), WBGene00005103(srd-25), WBGene00005104(srd-26), WBGene00005105(srd-27), WBGene00005106(srd-28), WBGene00005107(srd-29), WBGene00005108(srd-30), WBGene00005109(srd-31)
Availability: unknown
Source References: EMPTY
Synonyms: srd-23(yum2172) srd-25(yum2173) srd-26(yum2174) srd-27(yum2175) srd-28(yum2176) srd-29(yum2177) srd-30(yum2178) srd-31(yum2179) IV.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062445 Copy
http://www.wormbase.org/db/get?name=WBStrain00062448
Source Database: WormBase (WB)
Affected Genes: WBGene00005877(srw-130)|WBGene00005886(srw-139)|WBGene00005887(srw-140)|WBGene00005888(srw-141)|WBGene00005889(srw-142)|WBGene00005890(srw-143)
Genomic Alteration: WBGene00005877(srw-130), WBGene00005886(srw-139), WBGene00005887(srw-140), WBGene00005888(srw-141), WBGene00005889(srw-142), WBGene00005890(srw-143)
Availability: unknown
Source References: EMPTY
Synonyms: srw-130(yum2194) srw-139(yum2195) srw-140(yum2196) srw-141(yum2197) srw-142(yum2198) srw-143(yum2199) V.
Notes: Engineered null mutations in predicted GPCR genes. Reference: Pu L, et al. Nat Commun. 2023 Dec 18;14(1):8410. PMID: 38110404.|"Made_by: CCHEN group"
Proper citation: RRID:WB-STRAIN:WBStrain00062448 Copy
http://www.wormbase.org/db/get?name=WBStrain00062540
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: nmIs12.
Notes: Made_by: Justin Van Goor|"nmIs12 [Cbr-msrp-3(+) + Cbr-unc-119(+) + myo-2::GFP]. GFP expression in pharynx. Wild-type (non-Unc) movement. Roughly two-fold over-expression of Cbr-msrp-3(+); has no measurable effect on fertility. Cbr-MSRP-3 is a sperm surface glycoprotein with homologs in C. elegans and other species. Reference: Van Goor J, et al. Curr Biol. 2025 35:1-7."
Proper citation: RRID:WB-STRAIN:WBStrain00062540 Copy
http://www.wormbase.org/db/get?name=WBStrain00062544
Source Database: WormBase (WB)
Affected Genes: WBGene00017978(msrp-1)
Genomic Alteration: WBGene00017978(msrp-1)
Availability: unknown
Source References: EMPTY
Synonyms: Cbr-msrp-1(nm86) nmDf3 I; mfIs29.
Notes: Made_by: Asan Turdiev|"mfIs29 [Cel-lip-1::GFP + Cel-myo-2::GFP]. Strong GFP expression in pharynx and weak GFP expression in various somatic and germline tissues. nmDf3 is an 8411 bp deletion that removes Cbr-msrp-2, Cbr-msrp-3, Cbr-msrp-4, Cbr-msrp-6, and Cbr-msrp-6. Removal of all six Cbr-msrp paralogs has no apparent reproductive phenotypes. [NOTE: Van Goor J, et al. (2005) incorrectly described the nmDf3 as a 5807 bp deletion.] To confirm presence of nm86 mutation, use primers AT130+AT131 (WT: 184 nt, nm86: 224 nt). AT130: CGAAATAATTGAACCTACCAAGA. AT131: CACTCTCTCTGACTGCAAACG. To confirm presence of deletion, use primers AT72+AT73 (WT: 11213 nt, nmDf3: 2802) and AT20+AT75 (WT: 855 nt, nmDf3: no product). AT72: GTACGACGGATAGAGTGTGAT. AT73: CTGTGGGATTATGAAAAGACTC. AT20: AAAAGTAAAACATACCGATCACA. AT75: CAGCAGCAACCTTAGAACAT. Reference: Van Goor J, et al. Curr Biol. 2025 35:1-7."
Proper citation: RRID:WB-STRAIN:WBStrain00062544 Copy
http://www.wormbase.org/db/get?name=WBStrain00062548
Source Database: WormBase (WB)
Affected Genes: WBGene00006679(twk-26)
Genomic Alteration: WBGene00006679(twk-26)
Availability: unknown
Source References: EMPTY
Synonyms: twk-26(mac525) X.
Notes: Made_by: Chuanman Zhou|"twk-26 loss-of-function allele. Reference: Zhou C, et al. PLoS Genet. 2022;18: e1010126. doi:10.1371/journal.pgen.1010126. PMID: 35482723."
Proper citation: RRID:WB-STRAIN:WBStrain00062548 Copy
http://www.wormbase.org/db/get?name=WBStrain00062546
Source Database: WormBase (WB)
Affected Genes: WBGene00006662(twk-7)
Genomic Alteration: WBGene00006662(twk-7)
Availability: unknown
Source References: EMPTY
Synonyms: twk-7(mac510) III.
Notes: Made_by: Chuanman Zhou|"twk-7 loss-of-function allele. Hyperactive forward locomotion. twk-7(mac510) is a 10-bp deletion and 2-bp insertion in exon 9, causing a frameshift: aatttattttcagGTAAAAAAGAACGCAGCAACGGAGACATGGACATTTTCATCGTCCATTTTCTTTGCCGTAACCGTCGTCACTACCATCGGATACGGTAATCCAGTTCCAGTGACAAACATTGGACGGATATGGTGTATATTGTTCTCCTTGCTTGGAA(TACCTCTAAC)del(AA)insACTGGTTACCATCGCTGACTTGGgtaagtgg. Reference: Zhou C, et al. PLoS Genet. 2022;18: e1010126. doi:10.1371/journal.pgen.1010126. PMID: 35482723."
Proper citation: RRID:WB-STRAIN:WBStrain00062546 Copy
http://www.wormbase.org/db/get?name=WBStrain00062539
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: nmIs11.
Notes: Made_by: Justin Van Goor|"nmIs11 [Cbr-msrp-3(+) + Cbr-unc-119(+) + myo-2::GFP]. GFP expression in pharynx. Wild-type (non-Unc) movement. Roughly two-fold over-expression of Cbr-msrp-3(+); has no measurable effect on fertility. Cbr-MSRP-3 is a sperm surface glycoprotein with homologs in C. elegans and other species. Reference: Van Goor J, et al. Curr Biol. 2025 35:1-7."
Proper citation: RRID:WB-STRAIN:WBStrain00062539 Copy
http://www.wormbase.org/db/get?name=WBStrain00062637
Source Database: WormBase (WB)
Affected Genes: WBGene00000603(col-14)
Genomic Alteration: WBGene00000603(col-14)
Availability: unknown
Source References: EMPTY
Synonyms: col-14(wrd271[col-14::mNG::3xFLAG]) IV.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted at the C-terminus of the endogenous col-14 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.
Proper citation: RRID:WB-STRAIN:WBStrain00062637 Copy
http://www.wormbase.org/db/get?name=WBStrain00062592
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: oxIs609 X.
Notes: oxIs609 [acr-5p::GAP-43::GFP + lin-15(+)] X. GFP localized to axonal membranes of acr-5 expressing neurons. acr-5 promoter drives expression of reporter containing 40 aa myristoylation sequence of GAP43 fused to GFP. oxIs609 was generated by X-ray integration of oxEx81in N2 background. Reference: Rawson RL, et al. Curr Biol. 2014 Mar 31;24(7):760-5. doi: 10.1016/j.cub.2014.02.025. PMID: 24631238.
Proper citation: RRID:WB-STRAIN:WBStrain00062592 Copy
http://www.wormbase.org/db/get?name=WBStrain00062593
Source Database: WormBase (WB)
Affected Genes: WBGene00004873(smc-3)
Genomic Alteration: WBGene00004873(smc-3)
Availability: unknown
Source References: EMPTY
Synonyms: ieSi57 II; smc-3(syb5520[smc-3::GGGGS::AID::emGFP]) III.
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the soma. Degron and emGFP tag inserted into endogenous smc-3 locus. Derived by crossing parental strains PHX5520 with CA1200. Reference: https:|"Made_by: Jun Kim"
Proper citation: RRID:WB-STRAIN:WBStrain00062593 Copy
http://www.wormbase.org/db/get?name=WBStrain00062631
Source Database: WormBase (WB)
Affected Genes: WBGene00001075(dpy-14)
Genomic Alteration: WBGene00001075(dpy-14)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-14(wrd229[dpy-14::mNG::3xFLAG]) I.
Notes: Modular linker::mNeonGreen::3xFLAG::linker tag inserted at the C-terminus of the endogenous dpy-14 locus by CRISPR. Allele obtained using Cas9 RNP. Cassette design allows for re-editing of locus with common crRNAs/sgRNAs.
Proper citation: RRID:WB-STRAIN:WBStrain00062631 Copy
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