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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue Issue
http://www.taconic.com/mouse-model/hgm-csfhil3-nog
Source Database: Taconic Biosciences
Affected Genes: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide
Genomic Alteration: targeted mutation 1; Kazuo Sugamura|severe combined immunodeficiency
Availability: live
Notes: gene symbol note: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide; mutant strain|congenic strain: Il2rg|Prkdc
Proper citation: RRID:IMSR_TAC:13395 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abbb2m
Source Database: Taconic Biosciences
Affected Genes: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; Rudolf Jaenisch|targeted mutation 1; Michael J Grusby
Availability: archived
Synonyms: B6.129S2-H2-Ab1<b-tm1Gru> B2m<tm1Jae>/2Tac. B6.129S2-H2-Ab1<tm1Gru> B2m<tm1Jae>/2Tac
Notes: gene symbol note: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1; mutant strain|congenic strain: B2m|H2-Ab1
Proper citation: RRID:IMSR_TAC:4080 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abb-h2-ab1-model-4026
Source Database: Taconic Biosciences
Affected Genes: histocompatibility 2; class II antigen A; beta 1|protein tyrosine phosphatase receptor type C
Genomic Alteration: targeted mutation 1; Michael J Grusby|a variant
Availability: archived
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1|protein tyrosine phosphatase receptor type C; mutant strain|congenic strain: H2-Ab1|Ptprc
Proper citation: RRID:IMSR_TAC:4026 Copy
Issue
https://www.taconic.com/transgenic-mouse-model/b2m-beta2m
Source Database: Taconic Biosciences
Affected Genes: |beta-2 microglobulin
Genomic Alteration: |targeted mutation 1; Rudolf Jaenisch
Availability: archived
Synonyms: B6.129S2-B2m<tm1Jae>/Tac. B2MN12. B2m (beta2m)
Notes: gene symbol note: |beta-2 microglobulin; mutant strain|congenic strain: |B2m
Proper citation: RRID:IMSR_TAC:B2MN12 Copy
Issue
http://www.taconic.com/transgenic-mouse-model/abb-h2-ab1-model-abbn12
Source Database: Taconic Biosciences
Affected Genes: histocompatibility 2; class II antigen A; beta 1|
Genomic Alteration: targeted mutation 1; Michael J Grusby|
Availability: live
Synonyms: ABBN12. B6.129S2-H2-Ab1<tm1Gru>/Tac. B6.129S2-H2-Ab1<b-tm1Gru>/Tac. Abb (H2-Ab1)
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1|; mutant strain|congenic strain: H2-Ab1|
Proper citation: RRID:IMSR_TAC:ABBN12 Copy
Issue Issue
http://www.taconic.com/mouse-model/ciea-nog-mouse
Source Database: Taconic Biosciences
Affected Genes: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide|
Genomic Alteration: targeted mutation 1; Kazuo Sugamura|severe combined immunodeficiency|
Availability: live
Synonyms: CIEA NOG
Notes: gene symbol note: interleukin 2 receptor; gamma chain|protein kinase; DNA activated; catalytic polypeptide|; mutant strain|congenic strain: Il2rg|Prkdc|
Proper citation: RRID:IMSR_TAC:NOG Copy
Issue
https://www.taconic.com/knockout-mouse/csmd1-targeted
Source Database: Taconic Biosciences
Affected Genes: CUB and Sushi multiple domains 1
Genomic Alteration: targeted mutation 1; Lexicon Genetics
Availability: archived
Notes: gene symbol note: CUB and Sushi multiple domains 1; mutant strain: Csmd1
Proper citation: RRID:IMSR_TAC:TF0137 Copy
Issue Issue
https://archive.har.mrc.ac.uk/stock?id=1974
Source Database: MRC Harwell
Affected Genes: prion protein
Genomic Alteration: targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: STOCK Prnp<tm1Cwe> Tg(Prnp/PRNP)1Drb/H
Notes: gene symbol note: prion protein; congenic strain: Prnp
Proper citation: RRID:IMSR_HAR:1974 Copy
Issue Issue
https://archive.har.mrc.ac.uk/stock?id=1975
Source Database: MRC Harwell
Genomic Alteration: transgene insertion K6M16; Peter Griffiths
Availability: embryo
Notes: gene symbol note: ; mutant stock:
Proper citation: RRID:IMSR_HAR:1975 Copy
Issue Issue
https://www.envigo.com/model/b6-129-rag2tm1fwaii2rgtm1rsky-dwlhsd
Source Database: Envigo an Inotiv Company
Affected Genes: recombination activating gene 2|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; University of Cologne
Availability: live
Synonyms: B6;129-Rag2<tm1Fwa> II2rg<tm1Cgn>/DwlHsd
Notes: gene symbol note: recombination activating gene 2|interleukin 2 receptor; gamma chain; mutant strain|inbred strain: Rag2|Il2rg
Proper citation: RRID:IMSR_ENV:HSD-021 Copy
Issue
https://brc.riken.jp/mus/RBRC11145
Source Database: RIKEN BioResource Research Center
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Synonyms: MXH51-Fas<lpr>/Kod
Notes: gene symbol note: Fas cell surface death receptor; recombinant congenic: Fas
Proper citation: RRID:IMSR_RBRC11145 Copy
Issue
https://brc.riken.jp/mus/RBRC11808
Source Database: RIKEN BioResource Research Center
Affected Genes: transgene insertion 1; Shinobu Kitazume|transgene insertion 1; Masashi Yanagisawa
Genomic Alteration: transgene insertion 1; Shinobu Kitazume|transgene insertion 1; Masashi Yanagisawa
Availability: sperm
Notes: gene symbol note: transgene insertion 1; Shinobu Kitazume|transgene insertion 1; Masashi Yanagisawa; mutant strain: Tg(CAG-hAPP770)Skita|Tg(Tek-cre)1Ywa
Proper citation: RRID:IMSR_RBRC11808 Copy
Issue
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: apolipoprotein A-I|apolipoprotein E
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: live
Notes: gene symbol note: apolipoprotein A-I|apolipoprotein E; mutant strain|congenic strain: Apoa1|Apoe
Proper citation: RRID:IMSR_ARC:APOE Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
Synonyms: TLR2 KO. B6.129P2-Tlr2<tm1Aki>/Obs
Notes: gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2
Proper citation: RRID:IMSR_OBS:3 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-model.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|unknown|targeted mutation 1; University of Cologne
Availability: live
Synonyms: C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn>/Geno
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain; coisogenic strain|mutant strain: Rag2|Flt3|Sirpa|Il2rg
Proper citation: RRID:IMSR_BRGSF Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr2<tm1Aki>/Obs. TLR2 KO BALB/c
Notes: gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2
Proper citation: RRID:IMSR_OBS:9 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-a2-his.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|targeted mutation 1; University of Cologne|unknown|transgene insertion 1; Beatrice Perarnau
Availability: live
Synonyms: C.Cg-Rag2<tm1Fwa> Sirpa<Idd13.2-NOD/ShiLt> Flt3<tm1Irl> Il2rg<tm1Cgn> Tg(HLA-A/H2-D/B2M)1Bpe/Geno
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin; coisogenic strain|mutant strain: Rag2|Flt3|Il2rg|Sirpa|H2-D|HLA-A2.1|B2m
Proper citation: RRID:IMSR_BRGSF-A2 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=37
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Synonyms: C57BL/6 - lpr. B6-Tnfrsf6<lpr>/Orl
Alternate IDs: SCR_006136
Notes: gene symbol note: Fas cell surface death receptor; congenic strain: Fas
Proper citation: RRID:IMSR_EM:00037 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=30
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Christophe Benoist and Diane Mathis
Availability: embryo
Synonyms: B6.Cg-B2m<tm1Unc>H2-Ab1<tm1Doi>/DoiOrl. beta2m<0>. Abeta<0>(MHC). B6.129-B2m<tm1Unc> H2-Ab1<tm1Doi>/DoiOrl
Alternate IDs: SCR_006136
Notes: gene symbol note: beta-2 microglobulin|histocompatibility 2; class II antigen A; beta 1; mutant strain: B2m|H2-Ab1
Proper citation: RRID:IMSR_EM:00030 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=64
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion e19h; Charles Weissmann
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion e19h; Charles Weissmann
Availability: embryo
Synonyms: PrPC-KO. E1931. B6;129S7-Prnp<tm1Cwe> Tg(Prnp)e19hCwe/CweIbcm. B6;129S7 Prnp<tm1Cwe>-Tg(Prnp)e19hCwe/Cwe. E1931-Tg. STOCK Prnp<tm1Cwe> Tg(Prnp)E1931Cwe
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion e19h; Charles Weissmann; mutant strain: Prnp|Tg(Prnp)e19hCwe
Proper citation: RRID:IMSR_EM:00064 Copy
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