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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://www.jax.org/strain/023807
Source Database: JAX Mice and Services
Affected Genes: notch 3
Genomic Alteration: targeted mutation 1; Tom Gridley
Availability: sperm
Synonyms: FVB.129S1(B6)-Notch3<tm1Grid>/MshaJ
Notes: gene symbol note: notch 3; mutant stock: Notch3
Proper citation: RRID:IMSR_JAX:023807 Copy
Issue
https://www.jax.org/strain/030896
Source Database: JAX Mice and Services
Affected Genes: apolipoprotein E|C-C motif chemokine receptor 2|C-C motif chemokine receptor 5
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1.1; Bruno Luckow|targeted mutation 3.1; Bruno Luckow
Availability: embryo
Notes: gene symbol note: apolipoprotein E|C-C motif chemokine receptor 2|C-C motif chemokine receptor 5; mutant strain|congenic strain: Apoe|Ccr2|Ccr5
Proper citation: RRID:IMSR_JAX:030896 Copy
Issue
https://www.jax.org/strain/030892
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 1|apolipoprotein E
Genomic Alteration: targeted mutation 1; Ji-Liang Gao|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: C-C motif chemokine receptor 1|apolipoprotein E; mutant strain|congenic strain: Ccr1|Apoe
Proper citation: RRID:IMSR_JAX:030892 Copy
Issue
https://www.jax.org/strain/030893
Source Database: JAX Mice and Services
Affected Genes: C-C motif chemokine receptor 2|apolipoprotein E
Genomic Alteration: targeted mutation 1.1; Bruno Luckow|targeted mutation 1; University of North Carolina
Availability: sperm
Notes: gene symbol note: C-C motif chemokine receptor 2|apolipoprotein E; mutant strain|congenic strain: Ccr2|Apoe
Proper citation: RRID:IMSR_JAX:030893 Copy
Issue
https://www.jax.org/strain/032429
Source Database: JAX Mice and Services
Affected Genes: pancreatic and duodenal homeobox 1|transformation related protein 53|transgene insertion; Douglas A Melton|Cre recombinase and estrogen receptor 1 fusion gene|Kras proto-oncogene; GTPase
Genomic Alteration: transgene insertion; Douglas A Melton|targeted mutation 1; Anton Berns|targeted mutation 4; Tyler Jacks
Availability: live
Notes: gene symbol note: pancreatic and duodenal homeobox 1|transformation related protein 53|transgene insertion; Douglas A Melton|Cre recombinase and estrogen receptor 1 fusion gene|Kras proto-oncogene; GTPase; mutant stock: Pdx1|Trp53|Tg(Pdx1-cre/Esr1*)#Dam|cre/Esr1|Kras
Proper citation: RRID:IMSR_JAX:032429 Copy
Issue
https://www.jax.org/strain/033761
Source Database: JAX Mice and Services
Affected Genes: Kras proto-oncogene; GTPase|gene trap ROSA 26; Philippe Soriano|NK3 homeobox 1||phosphatase and tensin homolog
Genomic Alteration: targeted mutation 4; Tyler Jacks|targeted mutation 3; Hongkui Zeng|targeted mutation 4; Michael M Shen|targeted mutation 1; Hong Wu
Availability: live
Notes: gene symbol note: Kras proto-oncogene; GTPase|gene trap ROSA 26; Philippe Soriano|NK3 homeobox 1||phosphatase and tensin homolog; mutant stock: Kras|Gt(ROSA)26Sor|Nkx3-1||Pten
Proper citation: RRID:IMSR_JAX:033761 Copy
Issue
https://www.jax.org/strain/033910
Source Database: JAX Mice and Services
Affected Genes: insulin II|insulin I
Genomic Alteration: targeted mutation 1; Massimo Trucco|targeted mutation 1; Jacques Jami
Availability: sperm
Notes: gene symbol note: insulin II|insulin I; mutant strain|congenic strain: Ins2|Ins1
Proper citation: RRID:IMSR_JAX:033910 Copy
Issue Issue
https://brc.riken.jp/mus/RBRC04918
Source Database: RIKEN BioResource Research Center
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: embryo
Notes: gene symbol note: interleukin 6; mutant stock: Il6
Proper citation: RRID:IMSR_RBRC04918 Copy
Issue Issue
https://brc.riken.jp/mus/RBRC04919
Source Database: RIKEN BioResource Research Center
Affected Genes: interleukin 6
Genomic Alteration: targeted mutation 1; Manfred Kopf
Availability: sperm
Synonyms: C.129S2-Il6<tm1Kopf>/YiwRbrc
Notes: gene symbol note: interleukin 6; mutant stock: Il6
Proper citation: RRID:IMSR_RBRC04919 Copy
Issue Issue
https://brc.riken.jp/mus/RBRC05550
Source Database: RIKEN BioResource Research Center
Affected Genes: |transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu|activation-induced cytidine deaminase|gene trap ROSA 26; Philippe Soriano
Genomic Alteration: |transgene insertion 9; Meinrad Busslinger|targeted mutation 1; University of Cologne|activation-induced cytidine deaminase|targeted mutation 1; Stuart Orkin
Availability: embryo
Synonyms: B6.Cg-Gt(ROSA)26Sor<tm1Sho> Ighm<tm1Cgn> Tg(Aicda-cre)9Mbu/HonRbrc
Notes: gene symbol note: |transgene insertion 9; Meinrad Busslinger|immunoglobulin heavy constant mu|activation-induced cytidine deaminase|gene trap ROSA 26; Philippe Soriano; mutant stock: |Tg(Aicda-cre)9Mbu|Ighm|Aicda|Gt(ROSA)26Sor
Proper citation: RRID:IMSR_RBRC05550 Copy
Issue
https://brc.riken.jp/mus/RBRC06798
Source Database: RIKEN BioResource Research Center
Affected Genes: Fas cell surface death receptor
Genomic Alteration: lymphoproliferation
Availability: embryo
Notes: gene symbol note: Fas cell surface death receptor; mutant strain: Fas
Proper citation: RRID:IMSR_RBRC06798 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1218
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: insulin II
Genomic Alteration: targeted mutation 1; Jacques Jami
Availability: embryo
Synonyms: Ins/2_LacZ_129
Alternate IDs: SCR_006136
Notes: gene symbol note: insulin II; mutant strain: Ins2
Proper citation: RRID:IMSR_EM:01218 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1332
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: shaker-with-syndactylism deletion region
Genomic Alteration: shaker with syndactylism
Availability: embryo
Synonyms: Hertwig's syndactylism
Alternate IDs: SCR_006136
Notes: gene symbol note: shaker-with-syndactylism deletion region; mutant strain: sy
Proper citation: RRID:IMSR_EM:01332 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1638
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin|recombination activating 1
Genomic Alteration: targeted mutation 1; Christophe Benoist and Diane Mathis|targeted mutation 1; University of North Carolina|targeted mutation 1; David Baltimore
Availability: embryo
Synonyms: NOD.129-Rag1<tm1Bal> B2m<tm1Unc> H2-Ab1<tm1Doi>/Orl. NOD-IAbeta-beta2m-RAG1-/-
Alternate IDs: SCR_006136
Notes: gene symbol note: histocompatibility 2; class II antigen A; beta 1|beta-2 microglobulin|recombination activating 1; mutant strain: H2-Ab1|B2m|Rag1
Proper citation: RRID:IMSR_EM:01638 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1723
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein
Genomic Alteration: targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: prp BL6
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein; mutant strain: Prnp
Proper citation: RRID:IMSR_EM:01723 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1837
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion; Adriano Aguzzi
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion; Adriano Aguzzi
Availability: embryo
Synonyms: NSE-PrP<o>. STOCK-Prnp<tm1Cwe> Tg(Eno-Prnp)/Cnrm. NSE-PrP<tg/-> Prnp<o/o>. B6.129-TgN[NSE]Prnp ZH1/ZH1
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion; Adriano Aguzzi; mutant strain: Prnp|Tg(Eno2-Prnp)#Aag
Proper citation: RRID:IMSR_EM:01837 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=2027
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein|transgene insertion 940; University Hospital Zurich
Genomic Alteration: targeted mutation 1; Charles Weissmann|transgene insertion 940; University Hospital Zurich
Availability: embryo
Synonyms: PrPmyc<o/o>. B6.129Sv-Tg940(myc).PrnpZH1/zH1. Tg940 PrPmyc<o/o>
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein|transgene insertion 940; University Hospital Zurich; mutant strain: Prnp|Tg(Prnp)940Zbz
Proper citation: RRID:IMSR_EM:02027 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=2140
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: frequently rearranged in advanced T cell lymphomas
Genomic Alteration: targeted mutation 1; Anton Berns
Availability: embryo
Synonyms: FVB.129P2-Frat1<tm1Brn>/Ibcm. F1H
Alternate IDs: SCR_006136
Notes: gene symbol note: frequently rearranged in advanced T cell lymphomas; mutant strain: Frat1
Proper citation: RRID:IMSR_EM:02140 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=2081
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: ret proto-oncogene
Genomic Alteration: targeted mutation 1; Frank Costantini
Availability: embryo
Synonyms: Ret KO. Cg-Ret<tm1Cos>/Kctt
Alternate IDs: SCR_006136
Notes: gene symbol note: ret proto-oncogene; mutant strain: Ret
Proper citation: RRID:IMSR_EM:02081 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=2106
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: interferon gamma
Genomic Alteration: targeted mutation 1; Timothy Stewart
Availability: embryo
Synonyms: BALB/cByJIco IFNg-/-. CByIco.129S7-Ifng<tm1Ts>/Ibcm. CBy.129S7-Ifng<tm1Ts>/Ibcm
Alternate IDs: SCR_006136
Notes: gene symbol note: interferon gamma; mutant strain: Ifng
Proper citation: RRID:IMSR_EM:02106 Copy
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