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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-model.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|unknown|targeted mutation 1; University of Cologne
Availability: live
Synonyms: C.Cg-Rag2
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|signal-regulatory protein alpha|interleukin 2 receptor; gamma chain; coisogenic strain|mutant strain: Rag2|Flt3|Sirpa|Il2rg
Proper citation: RRID:IMSR_BRGSF Copy
https://www.genoway.com/catalog/humanized-immune-checkpoints/st/hvista.htm
Source Database: genOway
Affected Genes: V-set immunoregulatory receptor
Genomic Alteration: targeted mutation 1.1; Genoway
Availability: live
Notes: gene symbol note: V-set immunoregulatory receptor; coisogenic strain|mutant strain: Vsir
Proper citation: RRID:IMSR_ICP3 Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: dysferlin
Genomic Alteration: progressive muscular dystrophy
Availability: live
Notes: gene symbol note: dysferlin; mutant strain|congenic strain: Dysf
Proper citation: RRID:IMSR_ARC:BLA Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr2
Notes: gene symbol note: toll-like receptor 2; mutant strain|congenic strain: Tlr2
Proper citation: RRID:IMSR_OBS:9 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: myeloid differentiation primary response gene 88
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: MyD88 KO BALB/c. C.129P2-Myd88
Notes: gene symbol note: myeloid differentiation primary response gene 88; mutant strain|congenic strain: Myd88
Proper citation: RRID:IMSR_OBS:8 Copy
Issue Issue
https://www.genoway.com/catalog/immunodeficient/brgsf-a2-his.htm
Source Database: genOway
Affected Genes: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin
Genomic Alteration: targeted mutation 1; Frederick W Alt|targeted mutation 1; Ihor R Lemischka|targeted mutation 1; University of Cologne|unknown|transgene insertion 1; Beatrice Perarnau
Availability: live
Synonyms: C.Cg-Rag2
Notes: gene symbol note: recombination activating gene 2|FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|signal-regulatory protein alpha|histocompatibility 2; D region|human major histocompatibility complex; class I; A2.1|beta-2 microglobulin; coisogenic strain|mutant strain: Rag2|Flt3|Il2rg|Sirpa|H2-D|HLA-A2.1|B2m
Proper citation: RRID:IMSR_BRGSF-A2 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 4
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr4
Notes: gene symbol note: toll-like receptor 4; mutant strain|congenic strain: Tlr4
Proper citation: RRID:IMSR_OBS:10 Copy
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 7
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: live
Synonyms: C.129P2(B6)-Tlr7
Notes: gene symbol note: toll-like receptor 7; mutant strain|congenic strain: Tlr7
Proper citation: RRID:IMSR_OBS:11 Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: X chromosome inactivation center
Genomic Alteration: X Chromosome controlling element a
Availability: live
Notes: gene symbol note: X chromosome inactivation center; inbred strain: Xic
Proper citation: RRID:IMSR_ARC:CBA Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: protein tyrosine phosphatase; receptor type; C|peptidase C
Genomic Alteration: a variant|b variant
Availability: live
Notes: gene symbol note: protein tyrosine phosphatase; receptor type; C|peptidase C; mutant strain|congenic strain: Ptprc|Pepc
Proper citation: RRID:IMSR_ARC:PTP Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: aryl-hydrocarbon receptor|phosphodiesterase 6B; cGMP; rod receptor; beta polypeptide|glutamate receptor; ionotropic; AMPA4 (alpha 4)|toll-like receptor 4|inversion; Chr 6; Jackson 1
Genomic Alteration: b-2 variant|retinal degeneration 1|spike wave discharge 1|defective lipopolysaccharide response|inversion; Chr 6; Jackson 1
Availability: live
Synonyms: C3H-Oas1b
Notes: gene symbol note: aryl-hydrocarbon receptor|phosphodiesterase 6B; cGMP; rod receptor; beta polypeptide|glutamate receptor; ionotropic; AMPA4 (alpha 4)|toll-like receptor 4|inversion; Chr 6; Jackson 1; inbred strain: Ahr|Pde6b|Gria4|Tlr4|In(6)1J
Proper citation: RRID:IMSR_ARC:C3H Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: protein kinase; DNA activated; catalytic polypeptide|interleukin 2 receptor; gamma chain
Genomic Alteration: severe combined immunodeficiency|targeted mutation 1; Warren J Leonard
Availability: live
Notes: gene symbol note: protein kinase; DNA activated; catalytic polypeptide|interleukin 2 receptor; gamma chain; mutant strain|congenic strain: Prkdc|Il2rg
Proper citation: RRID:IMSR_ARC:NSG Copy
The record is no longer available at this source.
Source Database: Animal Resources Centre
Affected Genes: forebrain weight 1|tyrosinase-related protein 1|forebrain weight 2|nonagouti|purinergic receptor P2X; ligand-gated ion channel; 7|glycoprotein (transmembrane) nmb|fascin actin-bundling protein 2|killer cell lectin-like receptor; subfamily D; member 1|audiogenic seizure prone 2|myosin VA|hemolytic complement|aryl-hydrocarbon receptor|cadherin 23 (otocadherin)
Genomic Alteration: DBA/2J|iris stromal atrophy|nonagouti|rs48804829 SNP allele with the T variant|iris pigment dispersion|age related hearing loss 18|audiogenic seizure prone 2|dilute|deficient|d variant|age related hearing loss 1
Availability: live
Notes: gene symbol note: forebrain weight 1|tyrosinase-related protein 1|forebrain weight 2|nonagouti|purinergic receptor P2X; ligand-gated ion channel; 7|glycoprotein (transmembrane) nmb|fascin actin-bundling protein 2|killer cell lectin-like receptor; subfamily D; member 1|audiogenic seizure prone 2|myosin VA|hemolytic complement|aryl-hydrocarbon receptor|cadherin 23 (otocadherin); inbred strain: Fbrwt1|Tyrp1|Fbrwt2|a|P2rx7|Gpnmb|Fscn2|Klrd1|Asp2|Myo5a|Hc|Ahr|Cdh23
Proper citation: RRID:IMSR_ARC:DB2 Copy
https://www.modelorg.bio/portal/article/index.html?id=178165&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: methyltransferase 4; N6-adenosine
Genomic Alteration: endonuclease-mediated mutation 1; Shanghai Model Organisms Center
Availability: live
Notes: gene symbol note: methyltransferase 4; N6-adenosine; mutant strain: Mettl4
Proper citation: RRID:IMSR_NM-KO-2102213 Copy
https://www.modelorg.bio/portal/article/index.html?id=209630&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: low density lipoprotein receptor
Genomic Alteration: endonuclease-mediated mutation 1; Shanghai Model Organisms Center
Availability: live
Notes: gene symbol note: low density lipoprotein receptor; mutant strain: Ldlr
Proper citation: RRID:IMSR_NM-KO-210198 Copy
https://www.modelorg.bio/portal/article/index.html?id=209607&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: recombination activating gene 2
Availability: live
Notes: gene symbol note: recombination activating gene 2; mutant strain: Rag2
Proper citation: RRID:IMSR_NM-KO-210231 Copy
https://en.modelorg.com/portal/article/index.html?id=179262&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: diacylglycerol kinase; eta
Genomic Alteration: endonuclease-mediated mutation 1; Shanghai Model Organisms Center
Availability: live
Notes: gene symbol note: diacylglycerol kinase; eta; mutant strain: Dgkh
Proper citation: RRID:IMSR_NM-KO-2103439 Copy
https://www.modelorg.bio/portal/article/index.html?id=209749&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: golgi membrane protein 1
Genomic Alteration: endonuclease-mediated mutation 1; Shanghai Model Organisms Center
Availability: live
Notes: gene symbol note: golgi membrane protein 1; mutant strain: Golm1
Proper citation: RRID:IMSR_NM-KO-210321 Copy
https://www.modelorg.bio/portal/article/index.html?id=180391&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: ATP-binding cassette; sub-family A member 4
Genomic Alteration: endonuclease-mediated mutation 1; Shanghai Model Organisms Center
Availability: live
Notes: gene symbol note: ATP-binding cassette; sub-family A member 4; mutant strain: Abca4
Proper citation: RRID:IMSR_NM-KO-2104711 Copy
https://www.modelorg.bio/portal/article/index.html?id=209860&post_type=3
Source Database: Shanghai Model Organisms Center, Inc.
Affected Genes: Maf bZIP transcription factor G
Availability: live
Notes: gene symbol note: Maf bZIP transcription factor G; mutant strain: Mafg
Proper citation: RRID:IMSR_NM-KO-210377 Copy
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