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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.jax.org/strain/012606
Source Database: JAX Mice and Services
Affected Genes: signal transducer and activator of transcription 1
Genomic Alteration: targeted mutation 1; David E Levy
Availability: live
Notes: gene symbol note: signal transducer and activator of transcription 1; mutant strain|congenic strain: Stat1
Proper citation: RRID:IMSR_JAX:012606 Copy
https://www.jax.org/strain/012601
Source Database: JAX Mice and Services
Affected Genes: |lymphatic vessel endothelial hyaluronan receptor 1
Genomic Alteration: targeted mutation 1; Jason G Cyster
Availability: live
Notes: gene symbol note: |lymphatic vessel endothelial hyaluronan receptor 1; mutant stock: |Lyve1
Proper citation: RRID:IMSR_JAX:012601 Copy
https://www.jax.org/strain/012603
Source Database: JAX Mice and Services
Affected Genes: transforming growth factor; beta receptor II
Genomic Alteration: targeted mutation 1; Stefan Karlsson
Availability: live
Notes: gene symbol note: transforming growth factor; beta receptor II; mutant stock: Tgfbr2
Proper citation: RRID:IMSR_JAX:012603 Copy
https://www.jax.org/strain/012586
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 1; Jeremy Nathans||solute carrier family 1 (glial high affinity glutamate transporter); member 3
Genomic Alteration: transgene insertion 1; Jeremy Nathans
Availability: live
Synonyms: B6.Cg-Tg(Slc1a3-cre/ERT)1Nat/J
Notes: gene symbol note: transgene insertion 1; Jeremy Nathans||solute carrier family 1 (glial high affinity glutamate transporter); member 3; mutant stock: Tg(Slc1a3-cre/ERT)1Nat||Slc1a3
Proper citation: RRID:IMSR_JAX:012586 Copy
https://www.jax.org/strain/012837
Source Database: JAX Mice and Services
Affected Genes: |transgene insertion 3779; Nigel Killeen|lck proto-oncogene; Src family tyrosine kinase
Genomic Alteration: transgene insertion 3779; Nigel Killeen
Availability: live
Synonyms: B6.Cg-Tg(Lck-cre)3779Nik/J
Notes: gene symbol note: |transgene insertion 3779; Nigel Killeen|lck proto-oncogene; Src family tyrosine kinase; mutant strain|congenic strain: |Tg(Lck-icre)3779Nik|Lck
Proper citation: RRID:IMSR_JAX:012837 Copy
https://www.jax.org/strain/012868
Source Database: JAX Mice and Services
Availability: live
Synonyms: (C57BL/6J x 129S8/SvEvNimrJ)F1/J
Notes: gene symbol note: ; unclassified:
Proper citation: RRID:IMSR_JAX:012868 Copy
https://www.jax.org/strain/012930
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano|
Genomic Alteration: targeted mutation 2; Philippe Soriano
Availability: live
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano|; mutant strain|congenic strain: Gt(ROSA)26Sor|
Proper citation: RRID:IMSR_JAX:012930 Copy
https://www.jax.org/strain/012809
Source Database: JAX Mice and Services
Affected Genes: disrupted in schizophrenia 1
Genomic Alteration: deletion
Availability: live
Notes: gene symbol note: disrupted in schizophrenia 1; inbred strain: Disc1
Proper citation: RRID:IMSR_JAX:012809 Copy
https://www.jax.org/strain/012886
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 73.12; Michael V Sofroniew||glial fibrillary acidic protein
Genomic Alteration: transgene insertion 73.12; Michael V Sofroniew
Availability: live
Notes: gene symbol note: transgene insertion 73.12; Michael V Sofroniew||glial fibrillary acidic protein; mutant strain|congenic strain: Tg(Gfap-cre)73.12Mvs||Gfap
Proper citation: RRID:IMSR_JAX:012886 Copy
https://www.jax.org/strain/012885
Source Database: JAX Mice and Services
Affected Genes: fibrillin 1
Genomic Alteration: targeted mutation 1; Harry C Dietz
Availability: live
Notes: gene symbol note: fibrillin 1; mutant strain|congenic strain: Fbn1
Proper citation: RRID:IMSR_JAX:012885 Copy
https://www.jax.org/strain/013071
Source Database: JAX Mice and Services
Affected Genes: hemoglobin beta chain complex|hemoglobin subunit gamma 1|hemoglobin subunit beta|hemoglobin alpha chain complex|hemoglobin; alpha
Genomic Alteration: targeted mutation 2; Timothy Townes|targeted mutation 3; Timothy Townes|targeted mutation 1; Timothy Townes
Availability: live
Synonyms: Townes SCD model. B6;129-Hba
Notes: gene symbol note: hemoglobin beta chain complex|hemoglobin subunit gamma 1|hemoglobin subunit beta|hemoglobin alpha chain complex|hemoglobin; alpha; mutant stock: Hbb|HBG1|HBB|Hba|HBA
Proper citation: RRID:IMSR_JAX:013071 Copy
https://www.jax.org/strain/013148
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 1; Constance L Cepko|platelet derived growth factor receptor; alpha polypeptide|
Genomic Alteration: transgene insertion 1; Constance L Cepko
Availability: live
Notes: gene symbol note: transgene insertion 1; Constance L Cepko|platelet derived growth factor receptor; alpha polypeptide|; coisogenic strain|mutant strain: Tg(Pdgfra-cre)1Clc|Pdgfra|
Proper citation: RRID:IMSR_JAX:013148 Copy
Ratings or validation data are available for this resource
https://www.jax.org/strain/013062
Source Database: JAX Mice and Services
Affected Genes: protein kinase; DNA activated; catalytic polypeptide|interleukin 3|transgene insertion 1; CJ Eaves|KIT ligand|colony stimulating factor 2|cytomegalovirus|interleukin 2 receptor; gamma chain
Genomic Alteration: severe combined immunodeficiency|transgene insertion 1; CJ Eaves|targeted mutation 1; Warren J Leonard
Availability: live
Synonyms: NSGS. NSG-SGM3
Notes: gene symbol note: protein kinase; DNA activated; catalytic polypeptide|interleukin 3|transgene insertion 1; CJ Eaves|KIT ligand|colony stimulating factor 2|cytomegalovirus|interleukin 2 receptor; gamma chain; mutant strain|congenic strain: Prkdc|IL3|Tg(CMV-IL3;CSF2;KITLG)1Eav|KITLG|CSF2|CMV|Il2rg
Proper citation: RRID:IMSR_JAX:013062 Copy
https://www.jax.org/strain/013590
Source Database: JAX Mice and Services
Affected Genes: B-Raf proto-oncogene; serine/threonine kinase|transgene insertion 13; Marcus Bosenberg|tyrosinase||phosphatase and tensin homolog
Genomic Alteration: targeted mutation 1; Martin McMahon|transgene insertion 13; Marcus Bosenberg|targeted mutation 1; Hong Wu
Availability: live
Synonyms: B6.Cg-Braf
Notes: gene symbol note: B-Raf proto-oncogene; serine/threonine kinase|transgene insertion 13; Marcus Bosenberg|tyrosinase||phosphatase and tensin homolog; mutant strain|congenic strain: Braf|BRAF|Tg(Tyr-cre/ERT2)13Bos|Tyr||Pten
Proper citation: RRID:IMSR_JAX:013590 Copy
https://www.jax.org/strain/013530
Source Database: JAX Mice and Services
Affected Genes: duplication; Chr 16; Y Eugene Yu 1
Genomic Alteration: duplication; Chr 16; Y Eugene Yu 1
Availability: live
Synonyms: B6;129S7-Dp(16Lipi-Zfp295)1Yey/J. B6129S-Dp(16Lipi-Zfp295)1Yey/J. B6.129S7-Dp(16Lipi-Zfp295)1Yey/J
Notes: gene symbol note: duplication; Chr 16; Y Eugene Yu 1; mutant strain|congenic strain: Dp(16Lipi-Zbtb21)1Yey
Proper citation: RRID:IMSR_JAX:013530 Copy
https://www.jax.org/strain/014096
Source Database: JAX Mice and Services
Affected Genes: carboxylesterase 1C
Genomic Alteration: targeted mutation 1.1; Oksana Lockridge
Availability: live
Synonyms: B6(Cg)-Ces1c
Notes: gene symbol note: carboxylesterase 1C; mutant strain|congenic strain: Ces1c
Proper citation: RRID:IMSR_JAX:014096 Copy
https://www.jax.org/strain/014094
Source Database: JAX Mice and Services
Affected Genes: SRY (sex determining region Y)-box 2||EGF-like repeats and discoidin I-like domains 3
Genomic Alteration: transgene insertion 1; Andrew P McMahon
Availability: live
Synonyms: B6N.Sox2-Cre. B6N.Cg-Tg(Sox2-cre)1Amc/J. B6NJ.Sox2Cre. B6N.Sox2Cre. B6NJ.Sox2-Cre
Notes: gene symbol note: SRY (sex determining region Y)-box 2||EGF-like repeats and discoidin I-like domains 3; mutant strain|congenic strain: Sox2||Edil3
Proper citation: RRID:IMSR_JAX:014094 Copy
https://www.jax.org/strain/014570
Source Database: JAX Mice and Services
Affected Genes: major histocompatibility complex; class I; A|protein kinase; DNA activated; catalytic polypeptide|transgene insertion 1; David V Serreze|interleukin 2 receptor; gamma chain|beta-2-microglobulin|major histocompatibility complex; class I; subtype A2.1
Genomic Alteration: transgene insertion 1; David V Serreze|severe combined immunodeficiency|targeted mutation 1; Warren J Leonard
Availability: live
Synonyms: NSG-HLA-A2/HHD
Notes: gene symbol note: major histocompatibility complex; class I; A|protein kinase; DNA activated; catalytic polypeptide|transgene insertion 1; David V Serreze|interleukin 2 receptor; gamma chain|beta-2-microglobulin|major histocompatibility complex; class I; subtype A2.1; mutant strain|congenic strain: HLA-A|Prkdc|Tg(HLA-A/H2-D/B2M)1Dvs|Il2rg|B2M|HLA-A2.1
Proper citation: RRID:IMSR_JAX:014570 Copy
https://www.jax.org/strain/014565
Source Database: JAX Mice and Services
Affected Genes: Fc fragment of IgG receptor and transporter|transgene insertion 32; Derry C Roopenian
Genomic Alteration: transgene insertion 32; Derry C Roopenian|targeted mutation 1; Derry C Roopenian
Availability: live
Synonyms: FcRn<-/-> hFcRn (32) T
Notes: gene symbol note: Fc fragment of IgG receptor and transporter|transgene insertion 32; Derry C Roopenian; mutant strain|congenic strain: FCGRT|Tg(FCGRT)32Dcr|Fcgrt
Proper citation: RRID:IMSR_JAX:014565 Copy
https://www.jax.org/strain/014593
Source Database: JAX Mice and Services
Affected Genes: interleukin 2 receptor; gamma chain|recombination activating gene 2
Genomic Alteration: targeted mutation 1.1; Richard A Flavell
Availability: live
Synonyms: C;129S4-Rag2
Notes: gene symbol note: interleukin 2 receptor; gamma chain|recombination activating gene 2; mutant stock: Il2rg|Rag2
Proper citation: RRID:IMSR_JAX:014593 Copy
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