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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
LE-Tg(GFAP-TK)Hcam Resource Report Resource Website |
RRID:RRRC_00764 | Rattus norvegicus | random insertion of human GFAP promoter driving herpes simples virus thymidine kinase Rat Resource and Research Center | 00764 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11087549, 11087549, RRRC_764, RRRC_0764, RRRC_00764 | 2026-08-15 03:04:28 | 0 | |||||
|
ZDF-Cnr1em1/Rrrc ZDF-Cnr1em1 Resource Report Resource Website |
RRID:RRRC_00800 | Rattus norvegicus | 11bp deletion from genomic DNAfor the cannabinoid-1 receptor (Cnr1)using Zinc-Fingers Nucleases. Animals are resistant to the development of type-2 diabetes. Rat Resource and Research Center | 00800 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695053, 14695053, RRRC_800, RRRC_0800, RRRC_00800 | 2026-08-15 03:04:28 | 0 | |||||
|
SD-Il15em1Soar Resource Report Resource Website 1+ mentions |
RRID:RRRC_00769 | Rattus norvegicus | Zinc finger nuclease mediated 7bp deletion within exon 2 of the Il15 gene, resulting in a frameshift and premature stop codon. Rat Resource and Research Center | 00769 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11087551, 11087551, RRRC_769, RRRC_0769, RRRC_00769 | 2026-08-15 03:04:28 | 2 | |||||
|
F344-Tg(Cx3cr1-cre/ERT2)3OttcRrrc Resource Report Resource Website |
RRID:RRRC_00927 | Rattus norvegicus | The transgene of LE-Tg(Cx3cr1-cre)3Ottc (RGD: 13441557) was crossed onto Fischer344 background by backcrossing the hybrid to Fischer344 and select for the presence of transgene. The donor LE transgenic was generated by microinjection of LE embyos with a BAC DNA containing the Cx3cr1-cre/ERT2 transgene which is composed of cre/ERT2 recombinase gene driven by the rat genomic Cx3cr1promoter. Rat Resource and Research Center | 00927 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_155641246, 155641246, RRRC_927, RRRC_0927, RRRC_00927 | 2026-08-15 03:04:29 | 0 | |||||
|
SD-Tg(DIO-mCherry)2OttcRrrc Resource Report Resource Website |
RRID:RRRC_00928 | Rattus norvegicus | The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. Expresses mCherry in cells of the brain transduced with a Cre-expression virus. Currently in SD background generated by backcrossing to LE-Tg(DIO-mCherry)2Ottc Rat Resource and Research Center | 00928 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521661, 150521661, RRRC_928, RRRC_0928, RRRC_00928 | 2026-08-15 03:04:28 | 0 | |||||
|
LE-Pdynem1(iCre)Ottc Resource Report Resource Website |
RRID:RRRC_01023 | Rattus norvegicus | This mutant rat was produced by targeted knocking adding in IRES-iCre to the 3' end of Pdyn in LE rat using CRISPR/Cas9 method. Rat Resource and Research Center | 01023 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo (as of 2026-02-06) | RGD_405100724, 405100724, RRRC_1023, RRRC_01023 | 2026-08-15 03:04:29 | 0 | |||||
|
LE-Synpoem2Kmh Resource Report Resource Website 1+ mentions |
RRID:RRRC_01025 | Rattus norvegicus | Exons 2 and 3 were deleted to eliminate all known Synaptopodin isoforms in the outbred Long Evans (Charles River 006). It is similar to RRRC strain #964 (LE-Synpoem1Kmh) (RGD:155782907), has a different mutation location upstream of exon 2. This strain is deposited at Rat Resource and Research Center | 01025 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2025-05-13) | RGD_616335891, 616335891, RRRC_1025, RRRC_01025 | 2026-08-15 03:04:29 | 1 | |||||
|
W/LnneRrrc Audiogenic Wistar rat Resource Report Resource Website 1+ mentions |
RRID:RRRC_00697 | Rattus norvegicus | Wistar rats maintained at the animal facility of the Ribeirao Preto School of Medicine at the University of Sao Paulo, Brazil, were tested for audiogenic seizures, using as criteria an SI and the L1 (ref. RGD:14695082). The WAR colony foundation stock was produced by mating animals displaying at least procursive behaviors in three consecutive tests, one every 4 days (two males and four females). Each couple produced two or three lit-ters, from which selected individuals displaying the highest SI and shortest L1 were mated, at adult age,with their fathers and mothers. From the second generation on, brother and sister matings were done, in a ratio of one male to two females, selected accordingto the criteria above. Rat Resource and Research Center | 00697 | inbred | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695083, 14695083, RRRC_697, RRRC_0697, RRRC_00697 | 2026-08-15 03:04:28 | 9 | |||||
|
SD-Tg(Thy1-APPDI)BWevn Resource Report Resource Website |
RRID:RRRC_00974 | Rattus norvegicus | This novel transgenic rat produces low levels of human familial cerebral amyloid angiopath (CAA) Dutch/Iowa E22Q/D23N mutant amyloid beta protein in brain and recapitulates many of the pathologic aspects of human small-vessel CAA. A pcDNA3 vector containing 2.1 kb of human APP (isoform 770) cDNA was used to introduce the mutations Swedish K670N/M671L, Dutch E693Q, and Iowa D694N using the QuikChange kit. The APP770-SwDI cDNA was amplified by PCR using primers containing the NheI five linker and SacII three linker. The PCR product of the APP770-SwDI was subcloned between exons II and IV of a Thy1.2 expression cassette using NheI and SacII restriction sites. The completed construct was microinjected into pronuclei of Sprague-Dawley single-cell embryos. Founder rats were identified by Southern blot analysis of tail DNA. Transgenic offspring were determined by PCR analysis of tail DNA. All subsequent analyses were performed with hemizygous transgenic rats. Rat Resource and Research Center | 00974 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryorecovery (as of 2025-10-30) | RGD_626168255, 626168255, RRRC_974, RRRC_0974, RRRC_00974 | 2026-08-15 03:04:29 | 0 | |||||
|
SD-Sdhbem2Ast Resource Report Resource Website |
RRID:RRRC_00854 | Rattus norvegicus | This mutant strain was generated by injecting TALEN targeting rat Sdhb into NTac:SD embryo. The resulting mutant is a 6 bp-deletion in Sdhb. Rat Resource and Research Center | 00854 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14694999, 14694999, RRRC_854, RRRC_0854, RRRC_00854 | 2026-08-15 03:04:28 | 0 | |||||
|
LE-Pvalbem1(flpo)Berke/Rrrc Resource Report Resource Website |
RRID:RRRC_00859 | Rattus norvegicus | A double-stranded DNA plasmid donor was synthesized to introduce self-cleaving peptide 2A (P2A),followed by Flpo recombinase,and the V5 peptide tag (GKPIPNPLLGLDST) before the termination codon in exon 5 of rat Parvalbumin. The CRISPR/Cas9 system was used to knock in the plasmid into the targeted gene in the Crl:LE embryo. (ref:bioRxiv preprint first posted online Aug. 7, 2018; doi: http://dx.doi.org/10.1101/386474. ) Rat Resource and Research Center | 00859 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14694847, 14694847, RRRC_859, RRRC_0859, RRRC_00859 | 2026-08-15 03:04:28 | 0 | |||||
|
SHR.WKY-(D16Rat88-D16Rat15)/Tja Resource Report Resource Website |
RRID:RRRC_00739 | Rattus norvegicus | This congenic strain was generated by introgressing the desired fragment from WKY/NCruk onto the genetic background of SHR/NCruk Rat Resource and Research Center | 00739 | congenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9854711, 9854711, RRRC_739, RRRC_0739, RRRC_00739 | 2026-08-15 03:04:28 | 0 | |||||
|
Zuc/VcJw Zucker fatty Resource Report Resource Website |
RRID:RRRC_00740 | Rattus norvegicus | The original background strain derived from Sherman and Merck stock M rats (13 M strain). Obese animals produced by crossing homozygous obese males to heterozygous lean females. Rat Resource and Research Center | 00740 | inbred | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695086, 14695086, RRRC_740, RRRC_0740, RRRC_00740 | 2026-08-15 03:04:28 | 0 | |||||
|
SD-Esr2em1Soar Resource Report Resource Website |
RRID:RRRC_00742 | Rattus norvegicus | Zinc finger nuclease targeting of exon 4 of the rat estrogen receptor-2 gene resulting in the deletion of exon 4 Rat Resource and Research Center | 00742 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11081149, 11081149, RRRC_742, RRRC_0742, RRRC_00742 | 2026-08-15 03:04:28 | 0 | |||||
|
SD-Tg(Fos-LacZ)Bhope Resource Report Resource Website 1+ mentions |
RRID:RRRC_00865 | Rattus norvegicus | The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Rats were rederived from frozen embryos in 2002 and bred onto SD background for >35 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center | 00865 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14390082, 14390082, RRRC_865, RRRC_0865, RRRC_00865 | 2026-08-15 03:04:28 | 2 | |||||
|
BDIX/IfzRrrc Resource Report Resource Website |
RRID:RRRC_00900 | Rattus norvegicus | BDIX/IFZ rats have been inbred in the Institute of Cell Biology, Essen and later in the Central Animal Facility,Essen for about 45 years. The BDIX/Ifz rats are extremely susceptible to ENU-induced development of tumors of the peripheral and central nervous system. Rat Resource and Research Center | 00900 | inbred | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521617, 150521617, RRRC_900, RRRC_0900, RRRC_00900 | 2026-08-15 03:04:28 | 0 | |||||
|
LE-Tg(DIO-iRFP)3Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00747 | Rattus norvegicus | The transgene contains Cre recombinase reporter rat expressing the red fluorescent protein gene (iRFP) driven by the EF1 alpha promoter. Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00747 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm; Cryorecovery | RGD_9588559, 9588559, RRRC_747, RRRC_0747, RRRC_00747 | 2026-08-15 03:04:28 | 1 | |||||
|
BDIX.BDIV-D10Got1-D10Rat45/ZteRrrc Resource Report Resource Website |
RRID:RRRC_00902 | Rattus norvegicus | The BDIX.BDIV-D10Got1-D10Rat45/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background. Rat Resource and Research Center | 00902 | congenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521614, 150521614, RRRC_902, RRRC_0902, RRRC_00902 | 2026-08-15 03:04:28 | 0 | |||||
|
BDIX.BDIV-Mss1c/ZteRrrc Resource Report Resource Website |
RRID:RRRC_00904 | Rattus norvegicus | strain haboring on a BDIX background a 22,3 MB BDIV Fragment called Mss1c which covers part of the Mss1 fragment. Homozygous rats of both sexes display resistence towards ENU-induced development of PNS tumors in terms of survival time and incidence. Rat Resource and Research Center | 00904 | congenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150520183, 150520183, RRRC_904, RRRC_0904, RRRC_00904 | 2026-08-15 03:04:28 | 0 | |||||
|
BDIX.BDIV-Mss1b/ZteRrrc Resource Report Resource Website |
RRID:RRRC_00905 | Rattus norvegicus | strain haboring on a BDIX background two BDIV Fragments generated by a double recombination, 37,3 and 20,0 Mb long,Mss1b1 and Mss1b2 both covering parts of the Mss1 fragment. Homozygous rats of both sexes display susceptibility towards ENU-induced development of PNS tumors in terms of survival time and incidence. Through the Mss1b1 and Mss1b2 fragments and the Mss1c fragment the Mss1 locus was fine-mapped between 82.9 and 85.2Mb Rat Resource and Research Center | 00905 | congenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521612, 150521612, RRRC_905, RRRC_0905, RRRC_00905 | 2026-08-15 03:04:28 | 0 |
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