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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13450922
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_13450922, 13450922, RRRC_798, RRRC_0798, RRRC_00798
Notes: Genetically Epilepsy-Prone Rats (GEPR-3) have moderate levels of seizure predisposition. This colony,initially referred to as an AGS (audiogenic response score) colony, was bred to exhibit clonic convulsions (moderate seizures with an ARS of 3) following a single wild running phase in response to sound. Siezures model human generalized tonic/clonic seizures. Rat Resource and Research Center
Proper citation: RRID:RRRC_00798 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=151356950
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_151356950, 151356950, RRRC_952, RRRC_0952, RRRC_00952
Notes: The lacZ gene was inserted between NcoI and SalI sites in exon 4 of the murine Fos gene . The linearized DNA was then microinjected into fertilized rat oocytes and line 1-8 was chosen for continuation. Initial SD rats were then bred onto Wistar background for >10 generations at NIDA IRP (Bruce Hope lab) Rat Resource and Research Center
Proper citation: RRID:RRRC_00952 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13208224
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryorecovery (as of 2025-08-29)
Alternate IDs: RGD_13208224, 13208224, RRRC_833, RRRC_0833, RRRC_00833
Notes: The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of Cas9 under the control of CAG promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center
Proper citation: RRID:RRRC_00833 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245527
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_7245527, 7245527, RRRC_663, RRRC_0663, RRRC_00663
Notes: derived from a cross between SHR/N and WKY/N starting in 1980; followed by selected brother/sister inbreedings from F2 generation forward, selecting WKHA for highest activity and lowest blood pressure Rat Resource and Research Center
Proper citation: RRID:RRRC_00663 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7364940
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_7364940, 7364940, RRRC_661, RRRC_0661, RRRC_00661
Notes: Backcrossed STOCK-Tp53tm1(EGFP-Pac)QlyRrrc with F344 using speed congenic approach to move mutation onto F344 genetic background. Rat Resource and Research Center
Proper citation: RRID:RRRC_00661 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14398460
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_14398460, 14398460, RRRC_840, RRRC_0840, RRRC_00840
Notes: Zinc Finger Nuclease (ZFN) was utilized to knockout rat CD40 function in the embryos of SS/JrHsd rats. The target sequence (CAGCACCGACACTGCgaactcAGTGCGTGGGGCTGCCGGG) introduced an 11 bp-deletion (CTGCGAACTCA) in the third exon of the Cd40 gene, resulted in a trucated protein. Rat Resource and Research Center
Proper citation: RRID:RRRC_00840 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=152999002
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_152999002, 152999002, RRRC_961, RRRC_0961, RRRC_00961
Notes: Heterozygous KO of the Fxn gene obtained by targeting exon 4 with CRISPR/Cas9 system Rat Resource and Research Center
Proper citation: RRID:RRRC_00961 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695032
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14695032, 14695032, RRRC_844, RRRC_0844, RRRC_00844
Notes: A CAG-loxP-mCherry-loxP-EGFP cassette was injected into SD zygote to generate this line. The integration site is not determined. This transgenic line could be mated to other rat lines that express Cre/CreER for lineage tracing. Rat Resource and Research Center
Proper citation: RRID:RRRC_00844 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695028
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_14695028, 14695028, RRRC_847, RRRC_0847, RRRC_00847
Notes: This strain was made by electroporation of DAc8 embryonic stem cells with a targeting vector containing 6.3kb 5' and 2.1kb 3' homology arm. The Kcnh2 gene 7th and 8th exons are replaced with a CAG-EGFP-IRES-Pac cassette. Chimeras were formed by microinjecting into F344 blastocysts. Founder animals were mated with SD rats to produce this strain. Rat Resource and Research Center
Proper citation: RRID:RRRC_00847 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=405850257
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transchromosomal
Availability: Cryopreserved Sperm (as of 2025-02-03)
Alternate IDs: RGD_405850257, 405850257, RRRC_1021, RRRC_01021
Notes: Chimeric rats were generated using rBLK2i-1 (WDB/Nips-ES1/Nips, RGD: 10054010) to which human chromosome 21 was introduced. They were then backcrossed with Wistar rats (Crlj:WI) for more than 10 generations. National BioResource Project for the Rat in Japan,
Rat Resource and Research Center
Proper citation: RRID:RRRC_01021 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521611
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_150521611, 150521611, RRRC_899, RRRC_0899, RRRC_00899
Notes: The BDIX.BDIV-D6Mit8-D6Rat229/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background. Rat Resource and Research Center
Proper citation: RRID:RRRC_00899 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521660
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_150521660, 150521660, RRRC_687, RRRC_0687, RRRC_00687
Notes: The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. A Rrrc substrain available at Rat Resource and Research Center
Proper citation: RRID:RRRC_00687 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695060
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14695060, 14695060, RRRC_780, RRRC_0780, RRRC_00780
Notes: Transgenic strain using Sleeping Beauty transposon germline transgenesis, ubiquitously expressing green fluorescent protein (GFP) under the rat eukaryotic translation elongation factor 1 alpha (Eef1a1) promoter. Two integration sites located on chromosome 8:28170658 and chromosome 1:276465837, both located in intronic gene areas, Jam3 (RGD:1303248) intron 1 and Vti1a (RGD:621490) intron 6, respectively. The Jam3 intron 1 is 51bp long, and the transgene resides at 37kb from exon 1 and 13kb from exon 2. In Vti1a intron 6, 102 bp long, the transgene is located at 81.4 kb from exon 5 and 21 kb from exon 6. Rat Resource and Research Center
Proper citation: RRID:RRRC_00780 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=12903257
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_12903257, 12903257, RRRC_822, RRRC_0822, RRRC_00822
Notes: This congenic strain contains a fragment of chromosome 17 from the LH-Chr 17LN/Aek from rs199194111 through rs1056876746 transferred to the LH/MRrrcAek background. Rat Resource & Research Center
Proper citation: RRID:RRRC_00822 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695059
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_14695059, 14695059, RRRC_789, RRRC_0789, RRRC_00789
Notes: To develop BBDP rats congenic for the rnu mutation (nude BBDP), researchers introgressed the rnu mutation from inbred rnu/rnu WAG rats (obtained from Biomedical Research Models) using marker assisted genotyping. Rat Resource and Research Center
Proper citation: RRID:RRRC_00789 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13207339
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_13207339, 13207339, RRRC_824, RRRC_0824, RRRC_00824
Notes: This congenic strain contains a fragment of chromosome 17 from the LH-Chr 17LN/Aek from Fanccrgdv551196202-C through rs106387478 transferred to the LH/MRrrcAek background. Rat Resource & Research Center
Proper citation: RRID:RRRC_00824 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13207341
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_13207341, 13207341, RRRC_825, RRRC_0825, RRRC_00825
Notes: This congenic strain contains a fragment of chromosome 17 from the LH-Chr 17LN/Aek from Fanccrgdv551196202-C through rs107291522 transferred to the LH/MRrrcAek background. Rat Resource & Research Center
Proper citation: RRID:RRRC_00825 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13207416
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_13207416, 13207416, RRRC_826, RRRC_0826, RRRC_00826
Notes: This congenic strain contains a fragment of chromosome 17 from the LH-Chr 17LN/Aek from Fanccrgdv551196202-C through rs106387478 transferred to the LH/MRrrcAek background. Rat Resource & Research Center
Proper citation: RRID:RRRC_00826 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11040563
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_11040563, 11040563, RRRC_756, RRRC_0756, RRRC_00756
Notes: Cardiac specific overexpression of the alpha 1A adrenergic receptor, 40 fold overexpression of the receptor Rat Resource and Research Center
Proper citation: RRID:RRRC_00756 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521606
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_150521606, 150521606, RRRC_880, RRRC_0880, RRRC_00880
Notes: CRISPR/Cas9 system was used to introduce a 22-bp deletion at the sgRNA2 site of exon 2 in the rat Lrp5 gene of Crl:SD embryos. Rat Resource and Research Center
Proper citation: RRID:RRRC_00880 Copy
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