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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10401208
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Sperm (as of 2019-02-20)
Alternate IDs: RGD_10401208, 10401208, RRRC_699, RRRC_0699, RRRC_00699
Notes: The strain was coinjected with two transgenes: one contains the human amyloid beta (A4) precursor protein (hAPP) gene with the Swedish mutation (K595N/M596L) driven by mouse prion promoter (Prp). The other contains the human presenilin 1 gene (PS1) with a deletion of exon 9, also driven by the mouse prion promoter (Prp). Based on segregation patterns, it is believed that the two transgenes have integrated at the same chromosomal site. Rat Resource and Research Center
Proper citation: RRID:RRRC_00699 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14700890
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2021-02-12)
Alternate IDs: RGD_14700890, 14700890, RRRC_862, RRRC_0862, RRRC_00862
Notes: This strain was generated by microinjection of Sprague-Dawley embyos with a BAC DNA containing the Cx3cr1-cre/ERT2 transgene which is composed of cre/ERT2 recombinase gene driven by the rat genomic Cx3cr1promoter. Rat Resource & Research Center
Proper citation: RRID:RRRC_00862 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11081153
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2019-02-26)
Alternate IDs: RGD_11081153, 11081153, RRRC_748, RRRC_0748, RRRC_00748
Notes: The transgene contains Cre recombinase reporter rat expressing the red fluorescent protein gene (iRFP) driven by the EF1 alpha promoter. Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00748 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=126781838
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2024-01-10)
Alternate IDs: RGD_126781838, 126781838, RRRC_869, RRRC_0869, RRRC_00869
Notes: The 'docking site ready (DSR)' rat strain, or TARGAT /TM rat strain was generated using CRISPR/Cas9. With integrase, these TARGAT/DSR rats are used as embryo donors. TARGATT rat embryos will be microinjected with a mixture of TARGATT Cre DNA constructs containing human PDGFB promoter, a fluorescent reporter mCherry in the Cre cassette linked by a T2A sequence. The brain tissue-specific expression of a CreERT2 is also tamoxifen-dependent. Rat Resource and Research Center
Proper citation: RRID:RRRC_00869 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2292527
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_2292527, 2292527, RRRC_308, RRRC_0308, RRRC_00308
Notes: Dahl Sensitive rats were microinjected with AngII/AVP receptor gene and SV40 PolyA signal. Rat Resource and Research Center
Proper citation: RRID:RRRC_00308 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=4143165
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_4143165, 4143165, RRRC_427, RRRC_0427, RRRC_00427
Notes: This rat model was developed by perivitelline injection of one cell SD embryos with packaged lentiviral particles containing the pFUGW vector containing the Aqp5 promoter and the EGFP gene. Resulting transgenic founders with mated to wild-type SD rats and heterozygous offspring were obtained. Rat Resource and Research Center
Proper citation: RRID:RRRC_00427 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=401959229
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_401959229, 401959229, RRRC_1010, RRRC_01010
Notes: Pronuclear injection was used to introduce an expression cassette containing the Thy-1 enhancer and GCaMP6f protein coding sequence. GCaMP6f is a genetically encoded calcium indicator. It is a synthetic fusion of green fluorescent protein, calmodulin, and M13, a peptide sequence from myosin light-chain kinase. Reference ID: https://doi.org/10.1101/2023.08.17.553594 Rat Resource & Research Center
Proper citation: RRID:RRRC_01010 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155260361
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2022-10-06)
Alternate IDs: RGD_155260361, 155260361, RRRC_968, RRRC_0968, RRRC_00968
Notes: This project entailed generation of a novel rat strain in which a P2A-Cas9-T2A-EGFP coding sequence was inserted at the stop codon of the rat Sycp1 gene for co-expression of Cas9 and EGFP under the control of the Sycp1 regulatory elements. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin
URL: Doi:10.1101/2022.08.30.505951 Rat Resource and Research Center
Proper citation: RRID:RRRC_00968 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1554309
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_1554309, 1554309, RRRC_259, RRRC_0259, RRRC_00259
Notes: These transgenic rats are produced by the intracytoplasmic sperm injection (ICSI) using a Piezo-driven micromanipulator. National BioResource Project for the Rat in Japan, Rat Resource and Research Center
Proper citation: RRID:RRRC_00259 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482252
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6482252, 6482252, RRRC_53, RRRC_053, RRRC_0053, RRRC_00053
Notes: Multiple random integration of EGFP gene under the control of the PGK promoter. Rat Resource and Research Center
Proper citation: RRID:RRRC_00053 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566460
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2025-11-07)
Alternate IDs: RGD_1566460, 1566460, RRRC_51, RRRC_051, RRRC_0051, RRRC_00051
Notes: Embryos were microinjected with DNA containing the human CD55 (DAF, decay-acceletating factor) gene under control of the human ICAM2 promoter. Rat Resource and Research Center
Proper citation: RRID:RRRC_00051 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566453
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_1566453, 1566453, RRRC_49, RRRC_049, RRRC_0049, RRRC_00049
Notes: Fertilized eggs were microinjected with 300-500 copies of DNA per egg which comprised of an insert (5,230 bp) containing U3R region, the lacZ gene and the SV 40 polyadenylation signal which was excised from the bacterial plasmid. Rat Resource and Research Center
Proper citation: RRID:RRRC_00049 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482244
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6482244, 6482244, RRRC_282, RRRC_0282, RRRC_00282
Notes: SS/JrHsd embryos were microinjected with human APOA1 C3 promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00282 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2290429
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_2290429, 2290429, RRRC_310, RRRC_0310, RRRC_00310
Notes: SS/JrHsd embryos were microinjected with 1.57 kb human CETP cDNA construct into pSV-SPORT1 with human ApoC3 promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00310 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150524338
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2021-11-29)
Alternate IDs: RGD_150524338, 150524338, RRRC_919, RRRC_0919, RRRC_00919
Notes: This transgenic rat carrying the human " II or *002" allele of ERAP1 under mouse H-2K promoter control. The construct was made by Dr. Edd James, University of Southampton, UK. The II allele is generally considered to be a risk allele for ankylosing spondylitisThe original background strain is SD and the current background strain is mixed Lewis x SD. Rat Resource and Research Center
Proper citation: RRID:RRRC_00919 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482290
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6482290, 6482290, RRRC_62, RRRC_062, RRRC_0062, RRRC_00062
Notes: This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into Lewis rat embryos. Rat Resource and Research Center
Proper citation: RRID:RRRC_00062 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482288
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: RGD_6482288, 6482288, RRRC_85, RRRC_085, RRRC_0085, RRRC_00085
Notes: insertion of EGFP transgene with Ubiquitin C promoter Rat Resource and Research Center
Proper citation: RRID:RRRC_00085 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=329955365
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryorecovery (as of 2023-07-11)
Alternate IDs: RGD_329955365, 329955365, RRRC_866, RRRC_0866, RRRC_00866
Notes: Transgene insertion (human CD68-GFP) using Sleeping Beauty transposon system on Wistar Kyoto rats. Rat monocyte/macrophage reporter strain on a WKY background which has susceptibility to experimental glomerulonephritis. GFP expression occurs exclusively within blood monocytes and tissue macrophages. Rat Resource and Research Center
Proper citation: RRID:RRRC_00866 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=151356988
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_151356988, 151356988, RRRC_954, RRRC_0954, RRRC_00954
Notes: This transgenic was created by Dr. Bruce Hope at at NIDA IRP and donated to RRRC in 2022. The transgenic rats were created by injecting the cfos-eGFP construct to pronuclei of fertilized eggs obtained from Long Evans females. The 5 prime end of the transgenic DNA construct contained mouse genomic cFos (indluding the promoter and all exon and intron sequences) was fused with eGFP (including poly(A) tail derived from the IRES (phosphorylated-internal ribosomal entry site) of the EGFP Clontech (Cambridge, UK) vector. A single founder animal was identified. All subsequent breeding used hemizygous cfos-GFP male rats paired with wild-type Long Evans female rats obtained from Charles River Laboratories. Rats were bred on Long-Evans background for 13 generations Rat Resource and Research Center
Proper citation: RRID:RRRC_00954 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695033
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_14695033, 14695033, RRRC_843, RRRC_0843, RRRC_00843
Notes: A CAG-Flpe cassette was injected into SD zygote to generate this line. The integration site is not determined.This transgenic line could be used to mate with other rat models that contains FRT sites to remove the cassette that is flanked by those FRT sites. Rat Resource and Research Center
Proper citation: RRID:RRRC_00843 Copy
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