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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154612
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 598154612
Notes: The 16.25 kbps full length human DYT1 allele of TOR1A gene including upstream and downstream flanking regions were inserted into a pUC19 vector. Following linearization and purification the transgenes were used to generate transgenic rats by microinjection of the DNA construct into the pronucleus of rat zygotes. Transgenic rats were kept on Sprague–Dawley background and bred as hemizygotes using standard procedures. Genotypes of offspring were determined by PCR and sequencing of DNA extracted from ear biopsies. Primer pair 5′-TAAAAATGTGTATCCGAGTGGAAAT (forward) and 5′-AAGGACTGAGTGTTGTTTCTTTTC (reverse) amplified a 230 bp segment within the coding sequence of exon 5 under the following conditions: 94 °C for 1 min, 60 °C for 1 min and 72 °C for 1 min, 40 cycles. Only lines that showed stable germline transmission of the transgenes were used for further analyses.
Proper citation: RRID:RGD_598154612 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092579
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-27)
Alternate IDs: 598092579
Notes: Background strain: Long-Evans rat (Iar:Long-Evans). This strain was established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Tac1 gene) into Long-Evans rat's fertiled eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092579 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405849385
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 405849385
Notes: The hDNMT3A transgenic rats were established using zygote microinjection of a bacterial artificial chromosome (BAC). The RP11-159D24 BAC (NCBI-ID:223335, Homo sapiens, GRCh38.p2: Chr. 2: 25,202,642-25,410,145, total length: 207,504 bp) containing DNMT3A (GRCh38.p2: 25,232,961,25,342,590, total length: 109,630 bp) was injected into rat zygotes (Rattus norvegicus, Sprague-Dawley, SD). The offspring were identified with 8 PCR primer-pairs that were specific for the RP11-159D24 sequence to detect positive transgenic ones.
Proper citation: RRID:RGD_405849385 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=632522750
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 632522750
Notes: This is the wild type littermate of the transgenic rat strain carrying human NR3C2 (RGD:632522749).
Proper citation: RRID:RGD_632522750 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=626168247
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 626168247
Notes: A chimeric AVP-hM3Dq-mCherry BAC clone transgene construct was
purified for microinjections. hM3Dq is a modified form of the human M3 muscarinic receptor (hM3; CHRM3*). It can be activated by the inert clozapine metabolite clozapine-N-oxide (CNO), engaging the Gq signaling pathway.The hM3Dq-mCherry sequence from the hM3Dq-mCherry cassette (Plasmid
#44361, Addgene, Cambridge, MA, USA) was used for the transgene. Next, SV40 poly A sequence was framed to the hM3Dq-mCherry sequence. Finally, this
hM3Dq-mCherry-SV40 poly A cassette was introduced into the rat Avp gene in place of the genomic start
codon. Thus, hM3Dq-mCherry should be specifically expressed under the Avp promoter in the transgenic rat
brain.
Proper citation: RRID:RGD_626168247 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508380
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 5508380
Notes: These rats were made by pronuclear injection of a linear plasmid fragment containing a Sleeping Beauty oncogenic transposon harboring the CAG (chicken beta-actin/rabbit beta-globin hybrid promoter), the mouse Foxf2 exon 1 splice donor, and two Adenovirus 2 splice acceptors on opposite DNA strands.
Proper citation: RRID:RGD_5508380 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=5508381
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 5508381
Notes: These rats were made by pronuclear injection of a linear plasmid fragment containing a Sleeping Beauty oncogenic transposon harboring the CAG (chicken beta-actin/rabbit beta-globin hybrid promoter), the mouse Foxf2 exon 1 splice donor, and two Adenovirus 2 splice acceptors on opposite DNA strands.
Proper citation: RRID:RGD_5508381 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552368
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 8552368
Notes: The construct contains L2-Venus ÿ CAG-Cre (CAG--lox P--Venus--pA (3.1 kb)) which was injected into Crlj:WI embryos; now maintained as transgenic heterozygotes Section of Mammalian Transgenesis Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki Aichi, JAPAN
Proper citation: RRID:RGD_8552368 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552366
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 8552366
Notes: The construct contains CAG--NLS-Cre--pA (3.3 kb)which was injected into Crlj:WI embryos; now maintained as transgenic heterozygotes Section of Mammalian Transgenesis Center for Genetic Analysis of Behavior, National Institute for Physiological Sciences, Okazaki Aichi, JAPAN
Proper citation: RRID:RGD_8552366 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=9588576
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 9588576
Notes: The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons Optogenetics and Transgenic Technology Core
Proper citation: RRID:RGD_9588576 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=9587475
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 9587475
Notes: This strain was produced by microinjection of Col1a(5A)-Cre construct into embryos from SD-Tg(UBC-DsRedT3-emGFP)26Narl. As loxP-flanked DsRed is removed by Col1a(5A) promoter-driven Cre recombinase
Proper citation: RRID:RGD_9587475 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552279
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 8552279
Notes: The original work using this transgenic rat was published in Science (Yamazaki et al. 2000). This transgenic rat was generated in the Wistar outbred strain (Charles River, Japan). We maintained the L1 line. The transgenic rat was generated using a DNA construct in which the mouse Period1 promoter drives firefly luciferase National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552279 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=9587470
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo
Alternate IDs: 9587470
Notes: This strain was generated by microinjection of SD embyos with UBC-DsRed-emGFP transgene which is composed of DsRed flanked by loxP and followed by emerald GFP(emGFP). The transgene is driven by human UBC promoter. National Laboratory Animal Center, Taiwan
Proper citation: RRID:RGD_9587470 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552315
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 8552315
Notes: The transgenic rats were established by injection of transgene consisting of ChR2 and Venus fused transgene driven by the Thy-1.2 promoter into Wistar rat fertile eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552315 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552319
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 8552319
Notes: The transgenic rats were established by injection of transgene consisting of ChR2 and Venus fused transgene driven by the Thy-1.2 promoter into Wistar rat fertile eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552319 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552317
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 8552317
Notes: The transgenic rats were established by injection of transgene consisting of ChR2 and Venus fused transgene driven by the Thy-1.2 promoter into Wistar rat fertile eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552317 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552327
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 8552327
Notes: The transgenic rats were established by injection of transgene consisting of cholesterylester tansfer protein gene driven by the APOC4 promoter into SHR/Izm rat fertile eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552327 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552323
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 8552323
Notes: The transgenic rats were established by injection of transgene consisting of cholesterylester tansfer protein gene driven by the APOC4 promoter into SHR/Izm rat fertile eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552323 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552321
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo
Alternate IDs: 8552321
Notes: The transgenic rats were established by injection of transgene consisting of cholesterylester tansfer protein gene driven by the APOC3 promoter into SHR/Izm rat fertile eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552321 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8552249
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2017-08-16)
Alternate IDs: 8552249
Notes: This transgene consists of approximately 6kb of the CamK2a promoter followed by a gene encoding FLP, optimised for mamalian exprssion (FLPo). This rat remains unvalidated. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_8552249 Copy
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