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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00007986
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00001355(evl-17)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00001355(evl-17), WBGene00006752(unc-13)
Availability: available
Source References: PMID:8500652
Synonyms: evl-17(ar94)/dpy-5(e61) unc-13(e51) I.
Alternate IDs: WB-STRAIN:GS305, CGC_GS305
Notes: Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00007986 Copy
http://www.wormbase.org/db/get?name=WBStrain00008014
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00001349(evl-9)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00001349(evl-9), WBGene00006752(unc-13)
Availability: available
Source References: PMID:8500652
Synonyms: evl-9(ar121)/dpy-5(e61) unc-13(e51) I.
Alternate IDs: WB-STRAIN:GS454, CGC_GS454
Notes: Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00008014 Copy
http://www.wormbase.org/db/get?name=WBStrain00008442
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00000962(dhc-1)|WBGene00001067(dpy-5)|WBGene00006751(unc-11)
Genomic Alteration: WBGene00000254(bli-4), WBGene00000962(dhc-1), WBGene00001067(dpy-5), WBGene00006751(unc-11)
Availability: available
Source References: PMID:2379819
Synonyms: dhc-1(ct42) dpy-5(e61)/unc-11(e47) bli-4(e937) I.
Alternate IDs: WB-STRAIN:HR10, CGC_HR10
Notes: Heterozygtes are WT. Hets segregate WT, UncBli and DpyLet. ct42 homozygotes are inviable at all temperatures (recessive non-conditional larval lethal). ct42 is dominant temperature sensitive maternal effect lethal. ct42 hets give more inviable progeny at 25C than at 15C. dch-1 was previously called let-354(ct42).|"Made_by: Mains P"
Proper citation: RRID:WB-STRAIN:WBStrain00008442 Copy
http://www.wormbase.org/db/get?name=WBStrain00052037
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn11)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Made_by: UDN Screening Center|"rab-5 [D135D]. Silent BstAPI site added in D135D allele for ease of genotyping. Balancer marked with myo-2p::Venus. Reference: Huang et al. 2022. PMID: 35121658"
Proper citation: RRID:WB-STRAIN:WBStrain00052037 Copy
http://www.wormbase.org/db/get?name=WBStrain00052054
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn47)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Made_by: UDN Screening Center|"rab-5 [A29A]/tmC18 I. Control edit mutation maintained over tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5 [A29A] homozygotes (viable and fertile), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. NOTE: udn47 is essentially wild-type. Pick Venus+ to prevent non-Venus rab-5 [A29A] homozygotes from taking over the population and losing the balancer! Silent DdeI site added in A29A allele for ease of genotyping. Reference: Huang et al. 2022. PMID: 35121658"
Proper citation: RRID:WB-STRAIN:WBStrain00052054 Copy
http://www.wormbase.org/db/get?name=WBStrain00052050
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn64)/tmC18 [dpy-5(tmIs1236)] I; udnSi38 II.
Notes: Made_by: UDN Screening Center|"udnSi38 [rab5p::rab-5] II. Maintain at 20 degrees. rab-5 [D135N] variant edit #2 with a single copy of wild-type rab-5 integrated into chromosome II at ttTi5605 site (II: 0.77). Homozygous lethal rab-5 [D135N] mutation balanced by tmC18. Balancer marked with myo-2p::mCherry. Heterozygotes are WT with pharyngeal mCherry fluorescence, and segregate mCherry + heterozygotes, non-mCherry rab-5 [D135N] homozygotes (L1 lethal), and Dpy mCherry+ tmC18 homozygotes. Pick fertile wild-type mCherry+ to maintain. [D135N]/ [D135N]; udnSi38/udnSi38 double homozygotes are lethal. Reference: Huang et al. 2022. PMID: 35121658"
Proper citation: RRID:WB-STRAIN:WBStrain00052050 Copy
http://www.wormbase.org/db/get?name=WBStrain00052049
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn49)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Homozygous lethal rab-5 [A29P] mutation balanced by tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5 [A29P] homozygotes (L1 lethal), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. Silent DdeI site added in A29P for genotyping ease. Reference: Huang et al. 2022. PMID: 35121658|"Made_by: UDN Screening Center"
Proper citation: RRID:WB-STRAIN:WBStrain00052049 Copy
http://www.wormbase.org/db/get?name=WBStrain00052038
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn17)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Homozygous lethal rab-5 [Q78R] mutation balanced by tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5 [Q78R] homozygotes (L1 lethal), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. Silent KpnI site added in Q78R for genotyping ease. Reference: Huang et al. 2022. PMID: 35121658|"Made_by: UDN Screening Center"
Proper citation: RRID:WB-STRAIN:WBStrain00052038 Copy
http://www.wormbase.org/db/get?name=WBStrain00054650
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00009163(drsh-1)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00009163(drsh-1)
Availability: unknown
Source References: EMPTY
Synonyms: drsh-1(viz43)/tmC18[dpy-5(tmIs1200[myo-2p::mVenus])] I.
Notes: Made_by: J. H. Seemann|"[D943G] substitution mutation in conserved residue within RNAse III domain. Balancer marked with myo-2p::Venus. Pick fertile wild-type (non-Dpy) Venus+ to maintain. drsh-1(viz43) homozygous animals display heterochronic phenotypes beginning at L3/L4 molt and typically burst at the vulva in L4. Heterozygotes are wild-type with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus viz-43 homozygotes, and Dpy Venus+ tmC18 homozygotes. Reference: Barish S, et al. Human Mol Genet. 2022 Aug 25;31(17):2934-2950. doi: 10.1093/hmg/ddac085. PMID: 35405010."
Proper citation: RRID:WB-STRAIN:WBStrain00054650 Copy
http://www.wormbase.org/db/get?name=WBStrain00055439
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00004389(rnp-6)|WBGene00004496(rps-27)|WBGene00006789(unc-54)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00004389(rnp-6), WBGene00004496(rps-27), WBGene00006789(unc-54)
Availability: unknown
Source References: EMPTY
Synonyms: rnp-6(ve790[LoxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + LoxP])/tmC20 [dpy-5(tm9709)] I.
Notes: Early larval arrest. Deletion of 7256 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break in parental strain KR16. unc-11 dpy-5 homozygotes no longer carrying the duplication were outcrossed 5 times to N2 to remove dpy-5; however, unc-11 may still be in the background. rnp-6 deletion was balanced over tmC20 [dpy-5(tm9709)] by crossing with strain FX30235. Balanced heterozygotes are semi-Dpy GFP+, and segregate semi-Dpy GFP+, early larval lethal GFP+ (ve790 homozygotes), and non-GFP dpy-5 animals (tmC20 homozygotes). Maintain by picking semi-dpy GFP+. Left flanking Sequence: attaaaaacatggaggaattcgagaataca ; Right flanking sequence: GCCTGTTTTCGATGTCTGCCGAGTTTTCTT. sgRNA #4: TGGAAATACTGTCAAAGCGG; sgRNA #2: AGACATCGAAAACAGGCCGG. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.|"Made_by: RG KO Group"
Proper citation: RRID:WB-STRAIN:WBStrain00055439 Copy
http://www.wormbase.org/db/get?name=WBStrain00049794
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00001864(him-5)|WBGene00003396(mom-4)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00001864(him-5), WBGene00003396(mom-4)
Availability: unknown
Source References: PMID:33713117
Synonyms: dpy-5(e61) mom-4(or39) I/hT1 (I;III); him-5(e1490) V
Notes: Batch Strain object requested via get_NS_ids.pl
Proper citation: RRID:WB-STRAIN:WBStrain00049794 Copy
http://www.wormbase.org/db/get?name=WBStrain00062742
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00005077(src-1)|WBGene00006753(unc-14)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00005077(src-1), WBGene00006753(unc-14)
Availability: unknown
Source References: EMPTY
Synonyms: src-1(syb7248)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I; juIs76 II.
Notes: juIs76 [unc-25p::GFP + lin-15(+)] II. D381A substitution mutation generated by Cas9 genome editing. Balancer marked with myo-2p::Venus. Heterozygotes are wild-type with Venus+ pharynx, and will segregate wild-type with Venus+ pharynx (heterozygotes), embryonic lethality (syb7248 homozygotes), and Dpy with Venus+ pharynx (tmC20 homozygotes). GFP expression in GABAergic motor neurons. Reference: Mahadik S, et al. bioRxiv 2023.05.20.541322; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062742 Copy
http://www.wormbase.org/db/get?name=WBStrain00062924
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)
Genomic Alteration: WBGene00001067(dpy-5)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-5::mNG(syb3312) I.
Notes: Made_by: SunyBiotech|"mNG inserted at C-terminus of endogenous dpy-5 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062924 Copy
http://www.wormbase.org/db/get?name=WBStrain00062917
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004479(rps-10)|WBGene00006753(unc-14)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004479(rps-10), WBGene00006753(unc-14)
Availability: unknown
Source References: EMPTY
Synonyms: rps-10(cc2557)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I.
Notes: Balancer recombination happens frequently at 23-25C, strain must be maintained at 16-20C. Homozygous lethal mutation balanced by Dpy- and myo-2p::Venus-marked inversion. Heterozygotes are non-Dpy with relatively dim pharyngeal GFP (Venus) expression, and segregate heterozygous non-Dpy Venus+, non-Venus cc2557 homozygotes (L1 arrest), and Dpy with brighter Venus+ (tmC20 homozygotes). Pick wild-type Venus(+) and check for proper segregation of progeny to maintain. cc2557 is an engineered mutation creating an early stop (T8*). Presumptive rps-10 null. Heterozygous rps-10(cc2557)/tmC20 animals are delayed in development. Reference: Cenik ES, et al. Dev Cell. 2019 Mar 25;48(6):811-826.e6. doi: 10.1016/j.devcel.2019.01.019. PMID: 30799226.|"Made_by: Elif Sarinay Cenik & Agustian Surya"
Proper citation: RRID:WB-STRAIN:WBStrain00062917 Copy
http://www.wormbase.org/db/get?name=WBStrain00040930
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00006806(unc-74)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00006806(unc-74)
Availability: available
Source References: EMPTY
Synonyms: unc-74(x19) dpy-5(e61) I.
Alternate IDs: WB-STRAIN:ZZ1012, CGC_ZZ1012
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040930 Copy
http://www.wormbase.org/db/get?name=WBStrain00042260
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)
Genomic Alteration: WBGene00001067(dpy-5)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-5(e907) I; sEx11151.
Alternate IDs: WB-STRAIN:BC11151
Notes: Generated based on WC-CalTech XREF data|"Made_by: Baillie Lab"|"No longer available from the CGC catalogue 24/04/2020"|"sEx11151 [rCes F56E10.4::GFP + pCeh361]. Maintain by picking WT. WT animals are GFP+. Strain construction supported by Genome British Columbia and Genome Canada. Please acknowledge McKay et al, Cold Spring Harbor Symposia on Quantitative Biology 68: 159-169 2004 (WBPaper00006525)."
Proper citation: RRID:WB-STRAIN:WBStrain00042260 Copy
http://www.wormbase.org/db/get?name=WBStrain00042271
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)
Genomic Alteration: WBGene00001067(dpy-5)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-5(e907) I; sEx13689.
Alternate IDs: WB-STRAIN:BC13689
Notes: Generated based on CalTech XREF data|"Made_by: Baillie Lab"|"No longer available from the CGC catalogue 24/04/2020"|"sEx13689 [rCes F45G2.1::GFP + pCeh361]. Maintain by picking WT. WT animals are GFP+. Strain construction supported by Genome British Columbia and Genome Canada. Please acknowledge McKay et al, Cold Spring Harbor Symposia on Quantitative Biology 68: 159-169 2004 (WBPaper00006525)."
Proper citation: RRID:WB-STRAIN:WBStrain00042271 Copy
http://www.wormbase.org/db/get?name=WBStrain00042273
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)
Genomic Alteration: WBGene00001067(dpy-5)
Availability: available
Source References: EMPTY
Synonyms: dpy-5(e907) I; sEx14173.
Alternate IDs: WB-STRAIN:BC14173, CGC_BC14173
Notes: Generated based on CalTech XREF data|"No longer available from the CGC catalogue 24/04/2020"|"sEx14172[rCesK08F8.6::GFP + pCeh361]. Maintain by picking WT. WT animals are GFP+. Strain construction supported by Genome British Columbia and Genome Canada. Please acknowledge McKay et al, Cold Spring Harbor Symposia on Quantitative Biology 68: 159-169 2004 (WBPaper00006525). Was previously called BC14172."
Proper citation: RRID:WB-STRAIN:WBStrain00042273 Copy
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