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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00026920
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003014(lin-28)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003014(lin-28)
Availability: available
Source References: EMPTY
Synonyms: dpy-5(e61) lin-28(n719) I.
Alternate IDs: WB-STRAIN:MT2007, CGC_MT2007
Notes: Dpy. Egl.
Proper citation: RRID:WB-STRAIN:WBStrain00026920 Copy
http://www.wormbase.org/db/get?name=WBStrain00027263
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00001075(dpy-14)|WBGene00006753(unc-14)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00001075(dpy-14), WBGene00006753(unc-14)
Availability: available
Source References: PMID:8756352
Synonyms: dpy-5(e61) nDf43/dpy-14(e188) unc-14(e57) I.
Alternate IDs: WB-STRAIN:MT6356, CGC_MT6356
Notes: Heterozygotes are WT and segregate WT, DpyUncs and animals which arrest as L1 or L2 larvae (nDf43) homozygotes.
Proper citation: RRID:WB-STRAIN:WBStrain00027263 Copy
http://www.wormbase.org/db/get?name=WBStrain00027389
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003387(mod-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003387(mod-5)
Availability: available
Source References: EMPTY
Synonyms: mod-5(n3314) dpy-5(e61) I.
Alternate IDs: WB-STRAIN:MT11190, CGC_MT11190
Notes: Dpy. Serotonin hypersensitive. 5-HT hypersensitivity phenotype. Hyperslowing in locomotion assay.
Proper citation: RRID:WB-STRAIN:WBStrain00027389 Copy
http://www.wormbase.org/db/get?name=WBStrain00027334
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003186(mek-2)|WBGene00006320(sup-11)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003186(mek-2), WBGene00006320(sup-11)
Availability: available
Source References: PMID:7729691
Synonyms: mek-2(n2678)/sup-11(n403) dpy-5(e61) I.
Alternate IDs: WB-STRAIN:MT8667, CGC_MT8667
Notes: Heterozygotes are WT and segregate WT, Sterile Vuls and scrawny Dpys. n2678 is a suppressor of let-60(n1046) Muv. n2678 animals are Vul and recessive sterile. n2678 is a strong allele, probably null. See also WBPaper00002150.
Proper citation: RRID:WB-STRAIN:WBStrain00027334 Copy
http://www.wormbase.org/db/get?name=WBStrain00027345
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003036(lin-53)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003036(lin-53)
Availability: available
Source References: EMPTY
Synonyms: dpy-5(e61) lin-53(n833) I.
Alternate IDs: WB-STRAIN:MT8840, CGC_MT8840
Notes: Dpy. n833 is a synthetic Muv with lin-15A(n767).
Proper citation: RRID:WB-STRAIN:WBStrain00027345 Copy
http://www.wormbase.org/db/get?name=WBStrain00062742
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00005077(src-1)|WBGene00006753(unc-14)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00005077(src-1), WBGene00006753(unc-14)
Availability: unknown
Source References: EMPTY
Synonyms: src-1(syb7248)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I; juIs76 II.
Notes: juIs76 [unc-25p::GFP + lin-15(+)] II. D381A substitution mutation generated by Cas9 genome editing. Balancer marked with myo-2p::Venus. Heterozygotes are wild-type with Venus+ pharynx, and will segregate wild-type with Venus+ pharynx (heterozygotes), embryonic lethality (syb7248 homozygotes), and Dpy with Venus+ pharynx (tmC20 homozygotes). GFP expression in GABAergic motor neurons. Reference: Mahadik S, et al. bioRxiv 2023.05.20.541322; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062742 Copy
http://www.wormbase.org/db/get?name=WBStrain00062924
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)
Genomic Alteration: WBGene00001067(dpy-5)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-5::mNG(syb3312) I.
Notes: Made_by: SunyBiotech|"mNG inserted at C-terminus of endogenous dpy-5 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062924 Copy
http://www.wormbase.org/db/get?name=WBStrain00062917
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004479(rps-10)|WBGene00006753(unc-14)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004479(rps-10), WBGene00006753(unc-14)
Availability: unknown
Source References: EMPTY
Synonyms: rps-10(cc2557)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I.
Notes: Balancer recombination happens frequently at 23-25C, strain must be maintained at 16-20C. Homozygous lethal mutation balanced by Dpy- and myo-2p::Venus-marked inversion. Heterozygotes are non-Dpy with relatively dim pharyngeal GFP (Venus) expression, and segregate heterozygous non-Dpy Venus+, non-Venus cc2557 homozygotes (L1 arrest), and Dpy with brighter Venus+ (tmC20 homozygotes). Pick wild-type Venus(+) and check for proper segregation of progeny to maintain. cc2557 is an engineered mutation creating an early stop (T8*). Presumptive rps-10 null. Heterozygous rps-10(cc2557)/tmC20 animals are delayed in development. Reference: Cenik ES, et al. Dev Cell. 2019 Mar 25;48(6):811-826.e6. doi: 10.1016/j.devcel.2019.01.019. PMID: 30799226.|"Made_by: Elif Sarinay Cenik & Agustian Surya"
Proper citation: RRID:WB-STRAIN:WBStrain00062917 Copy
http://www.wormbase.org/db/get?name=WBStrain00034653
Source Database: WormBase (WB)
Affected Genes: WBGene00000431(ceh-6)|WBGene00001067(dpy-5)|WBGene00006765(unc-29)
Genomic Alteration: WBGene00000431(ceh-6), WBGene00001067(dpy-5), WBGene00006765(unc-29)
Availability: available
Source References: WBPaper00014592(PMID:EMPTY)
Synonyms: ceh-6(mg60)/dpy-5(e61) unc-29(e1072) I.
Alternate IDs: WB-STRAIN:TB1, CGC_TB1
Notes: ceh-6(mg60) is lethal. Maintain by picking WT and check that it throws 1/4 Dpys. mg60 is a 1.3 kb deletion that removes part of the conserved POU-specific domain. PCR with primers PCR6-5 GAA-TTC-ATG-AAA-TCG-GAG-GCG-T (->) and PCR6-3 GTG-AGA-AGT-GAA-GAG-GAT-TGT-A (<-) yields a band of about 1.6 kb instead of 280 bp as in N2. Backcrossed more than 10 times; in addition, the left arm of LG I was recombined with lin-28 to remove the mutator locus.|"Made_by: Tom Burglin"
Proper citation: RRID:WB-STRAIN:WBStrain00034653 Copy
http://www.wormbase.org/db/get?name=WBStrain00037917
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00004496(rps-27)|WBGene00006789(unc-54)|WBGene00011971(lron-9)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00004496(rps-27), WBGene00006789(unc-54), WBGene00011971(lron-9)
Availability: available
Source References: EMPTY
Synonyms: lron-9(gk5062[loxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + loxP])/tmC18 [dpy-5(tmIs1236)] I.
Alternate IDs: WB-STRAIN:VC4100, CGC_VC4100
Notes: Homozygous lethal deletion balanced by tmC18. Heterozygotes are wild-type GFP+ and segregate wild-type GFP+ heterozygotes and Dpy non-GFP (tmC18). Deletion of 2039 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break. Left flanking sequence: TGCTGTCGTATTTTTGTTACAGTACCTACG ; Right flanking sequence: GGTGGTTGGAAGATTCCATCAGCACGTGAT. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.|"Homozygous lethal deletion balanced by tmC18. Heterozygotes are WT with pharyngeal GFP, and segregate GFP heterozygotes, GFP gk5062 homozygotes (arrest stage undetermined), and tmC18 homozygotes (Dpy-5 with myo-2 mCherry). Pick fertile wild-type GFP+ to maintain. Deletion of 2039 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break. Left flanking sequence: TGCTGTCGTATTTTTGTTACAGTACCTACG ; Right flanking sequence: GGTGGTTGGAAGATTCCATCAGCACGTGAT. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation."|"Made_by: Vancouver KO Group"
Proper citation: RRID:WB-STRAIN:WBStrain00037917 Copy
http://www.wormbase.org/db/get?name=WBStrain00040930
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00006806(unc-74)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00006806(unc-74)
Availability: available
Source References: EMPTY
Synonyms: unc-74(x19) dpy-5(e61) I.
Alternate IDs: WB-STRAIN:ZZ1012, CGC_ZZ1012
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040930 Copy
http://www.wormbase.org/db/get?name=WBStrain00055439
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00004389(rnp-6)|WBGene00004496(rps-27)|WBGene00006789(unc-54)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00004389(rnp-6), WBGene00004496(rps-27), WBGene00006789(unc-54)
Availability: unknown
Source References: EMPTY
Synonyms: rnp-6(ve790[LoxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + LoxP])/tmC20 [dpy-5(tm9709)] I.
Notes: Early larval arrest. Deletion of 7256 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break in parental strain KR16. unc-11 dpy-5 homozygotes no longer carrying the duplication were outcrossed 5 times to N2 to remove dpy-5; however, unc-11 may still be in the background. rnp-6 deletion was balanced over tmC20 [dpy-5(tm9709)] by crossing with strain FX30235. Balanced heterozygotes are semi-Dpy GFP+, and segregate semi-Dpy GFP+, early larval lethal GFP+ (ve790 homozygotes), and non-GFP dpy-5 animals (tmC20 homozygotes). Maintain by picking semi-dpy GFP+. Left flanking Sequence: attaaaaacatggaggaattcgagaataca ; Right flanking sequence: GCCTGTTTTCGATGTCTGCCGAGTTTTCTT. sgRNA #4: TGGAAATACTGTCAAAGCGG; sgRNA #2: AGACATCGAAAACAGGCCGG. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.|"Made_by: RG KO Group"
Proper citation: RRID:WB-STRAIN:WBStrain00055439 Copy
http://www.wormbase.org/db/get?name=WBStrain00054650
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00009163(drsh-1)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00009163(drsh-1)
Availability: unknown
Source References: EMPTY
Synonyms: drsh-1(viz43)/tmC18[dpy-5(tmIs1200[myo-2p::mVenus])] I.
Notes: Made_by: J. H. Seemann|"[D943G] substitution mutation in conserved residue within RNAse III domain. Balancer marked with myo-2p::Venus. Pick fertile wild-type (non-Dpy) Venus+ to maintain. drsh-1(viz43) homozygous animals display heterochronic phenotypes beginning at L3/L4 molt and typically burst at the vulva in L4. Heterozygotes are wild-type with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus viz-43 homozygotes, and Dpy Venus+ tmC18 homozygotes. Reference: Barish S, et al. Human Mol Genet. 2022 Aug 25;31(17):2934-2950. doi: 10.1093/hmg/ddac085. PMID: 35405010."
Proper citation: RRID:WB-STRAIN:WBStrain00054650 Copy
http://www.wormbase.org/db/get?name=WBStrain00052037
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn11)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Made_by: UDN Screening Center|"rab-5 [D135D]. Silent BstAPI site added in D135D allele for ease of genotyping. Balancer marked with myo-2p::Venus. Reference: Huang et al. 2022. PMID: 35121658"
Proper citation: RRID:WB-STRAIN:WBStrain00052037 Copy
http://www.wormbase.org/db/get?name=WBStrain00052054
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn47)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Made_by: UDN Screening Center|"rab-5 [A29A]/tmC18 I. Control edit mutation maintained over tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5 [A29A] homozygotes (viable and fertile), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. NOTE: udn47 is essentially wild-type. Pick Venus+ to prevent non-Venus rab-5 [A29A] homozygotes from taking over the population and losing the balancer! Silent DdeI site added in A29A allele for ease of genotyping. Reference: Huang et al. 2022. PMID: 35121658"
Proper citation: RRID:WB-STRAIN:WBStrain00052054 Copy
http://www.wormbase.org/db/get?name=WBStrain00052050
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn64)/tmC18 [dpy-5(tmIs1236)] I; udnSi38 II.
Notes: Made_by: UDN Screening Center|"udnSi38 [rab5p::rab-5] II. Maintain at 20 degrees. rab-5 [D135N] variant edit #2 with a single copy of wild-type rab-5 integrated into chromosome II at ttTi5605 site (II: 0.77). Homozygous lethal rab-5 [D135N] mutation balanced by tmC18. Balancer marked with myo-2p::mCherry. Heterozygotes are WT with pharyngeal mCherry fluorescence, and segregate mCherry + heterozygotes, non-mCherry rab-5 [D135N] homozygotes (L1 lethal), and Dpy mCherry+ tmC18 homozygotes. Pick fertile wild-type mCherry+ to maintain. [D135N]/ [D135N]; udnSi38/udnSi38 double homozygotes are lethal. Reference: Huang et al. 2022. PMID: 35121658"
Proper citation: RRID:WB-STRAIN:WBStrain00052050 Copy
http://www.wormbase.org/db/get?name=WBStrain00052049
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn49)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Homozygous lethal rab-5 [A29P] mutation balanced by tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5 [A29P] homozygotes (L1 lethal), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. Silent DdeI site added in A29P for genotyping ease. Reference: Huang et al. 2022. PMID: 35121658|"Made_by: UDN Screening Center"
Proper citation: RRID:WB-STRAIN:WBStrain00052049 Copy
http://www.wormbase.org/db/get?name=WBStrain00052038
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004268(rab-5)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004268(rab-5)
Availability: unknown
Source References: EMPTY
Synonyms: rab-5(udn17)/tmC18 [dpy-5(tmIs1200)] I.
Notes: Homozygous lethal rab-5 [Q78R] mutation balanced by tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5 [Q78R] homozygotes (L1 lethal), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. Silent KpnI site added in Q78R for genotyping ease. Reference: Huang et al. 2022. PMID: 35121658|"Made_by: UDN Screening Center"
Proper citation: RRID:WB-STRAIN:WBStrain00052038 Copy
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