Searching the RRID Resource Information Network
Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.
Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=35668863
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 35668863
Notes: This strain was made by pronuclear injection into LEW/Crl embryos. The embryos were co-injected with DNA fragments containing the HLA-B*2705 human gene and the human beta-2-microglobulin gene. The strain carries 40 copies of HLA-B*2705 and 30 copies of human beta-2-microglobulin gene. Founder 21-3 was selected and carrier animals from this founder were mated and bred to homozygosity.
Proper citation: RRID:RGD_35668863 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=15045606
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 15045606
Notes: This transgenic strain line Tg12085 carries the dual-reporter LacZ/EGFP (enhanced green fluorescent protein) cloned into the rat Prnp vector (raPrnp) and the expression of transgenes were driven by rat Prnp promoter.
Proper citation: RRID:RGD_15045606 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=14981597
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 14981597
Notes: SD rats were microinjected with a linear 12 kb EcoRI-BamH1 fragment containing the coding sequence and promoter region of human SOD1 gene with G93A mutation. Originally created by John Kulik at Wyeth. Transgenic Model of SOD1 mediated Amyotrophic Lateral Sclerosis (ALS, Lou Gehrig's Disease). Came to Taconic in April 2002 for David Howland at Wyeth for distribution as an Emerging Model. Joint collaboration between Wyeth and The ALS Association. TACONIC
Proper citation: RRID:RGD_14981597 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=151356985
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 151356985
Notes: This LE transgenic rats were created by injecting the cfos-eGFP construct to pronuclei of fertilized eggs obtained from Long Evans females. The 5 prime end of the transgenic DNA construct contained mouse genomic cFos (indluding the promoter and all exon and intron sequences) was fused with eGFP (including poly(A) tail derived from the IRES (phosphorylated-internal ribosomal entry site) of the EGFP Clontech (Cambridge, UK) vector. A single founder animal was identified. All subsequent breeding used hemizygous cfos-GFP male rats paired with wild-type Long Evans female rats obtained from Charles River Laboratories. Rats were bred on Long-Evans background for 13 generations at NIDA IRP (Hope lab).
Proper citation: RRID:RGD_151356985 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38599204
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2020-09-15)
Alternate IDs: 38599204
Notes: The transgenic LE line 2(Back ground strain: Iar:Long-Evans (RGD:18337282) (Kumagai-shigeyasu Co.,Ltd)) carrying Transgene: ROSA26 (mouse ROSA26 BAC: RP23 244D9), and Channel rhodopsin fast receiver (ChRFR)(COP4*C167A) (Chlamydomonas reinhardtii) fused with YFP* (Venus). Copy number: 1, In this strain, COP4*C167A, modified photosensitivity cation channel, is expressed ubiquitously in the presence of exogenous Cre protein. The ChRFR(COP4*C167A), one of the channel rhodopsin (step-function opsin, SFO), opens under blue light and is closed under yellow light. The Venus (YFP*) is tagged with channel rhodopsin. There is no differences between line 1 and 2 except for copy number. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_38599204 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38599203
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2020-09-15)
Alternate IDs: 38599203
Notes: The transgenic LE line 2(Back ground strain: Iar:Long-Evans (RGD:18337282) (Kumagai-shigeyasu Co.,Ltd)) carrying Transgene: ROSA26 (mouse ROSA26 BAC: RP23 244D9), and Channel rhodopsin fast receiver (ChRFR)(COP4*C167A) (Chlamydomonas reinhardtii) fused with YFP* (Venus). Copy number: 3, In this strain, COP4*C167A, modified photosensitivity cation channel, is expressed ubiquitously in the presence of exogenous Cre protein. The ChRFR(COP4*C167A), one of the channel rhodopsin (step-function opsin, SFO), opens under blue light and is closed under yellow light. The Venus (YFP*) is tagged with channel rhodopsin. There is no differences between line 1 and 2 except for copy number. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_38599203 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=151356741
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 151356741
Notes: This transgenic strain was generated by microinjection into outbred Sprague-Dawley from Harlan Sprague-Dawley (Hsd:SD) fertilized eggs and carries simian virus T Antigen drived by the enhancer/promoter region of the mouse albumin gene.
Proper citation: RRID:RGD_151356741 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38599242
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2020-09-16)
Alternate IDs: 38599242
Notes: Mutant human amyloid beta (APP*) combined Thy1 promoter which is specifically expressed in neurons, was induced to ES cells from DA strain rats, and chimera rats obtained from the ES cells. The F1 rats were backcrossed with Crl:CD (SD) strain rats and F3 rats was deposited to NBRP. The expression levels of mutant human APP mRNA are difficult among Lines (12>1>14>6). National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_38599242 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=39131285
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 39131285
Notes: This Cre recombinase reporter rat expressing mCherry was generated by backcrossing Sprague-Dawley to LE-Tg(DIO-mCherry)2Ottc (RGD:8693598).
The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. Optogenetics and Transgenic Technology Core
Proper citation: RRID:RGD_39131285 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=38599244
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2020-09-16)
Alternate IDs: 38599244
Notes: Mutant human amyloid beta (APP*) combined Thy1 promoter which is specifically expressed in neurons, was induced to ES cells from DA strain rats, and chimera rats obtained from the ES cells. The F1 rats were backcrossed with Crl:CD (SD) strain rats and F3 rats was deposited to NBRP. The expression levels of mutant human APP mRNA are difficult among Lines (12>1>14>6). National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_38599244 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155663368
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 155663368
Notes: This transgenic model line 737 was made by injecting bacterial artificial chromosome (BAC) RNECO-180E22, into Crl:CD(SD) strain embryos. The BAC clone RNECO-180E22, a kind gift of Helen Skaletsky, is derived from Rattus norvegicus strain SHR chromosome Y.
Proper citation: RRID:RGD_155663368 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155260364
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2022-10-06)
Alternate IDs: 155260364
Notes: rat strain in which the rat Cyp3a1 gene (Cyp3a23-3a1, RGD:628626) was inactivated by insertion of a human CYP3A4 minigene (Cyp3A4*) and the linked rat Cyp3a2 locus was simultaneously mutated by CRISPR-mediated indel introduction. Strain contains Indel 8 at the Rat 3A2 locus (55 kb away), The CYP3A4 minigene included a CRISPR/Cas9 gene drive element to enable super-Mendelian inheritance. Strain contains and Active Genetic cassette which encodes a gRNA targeting the Rat 3A1 and 3A2 translation initiation site. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951
URL: URL: Doi:10.1101/2022.08.30.505951 RRRC
Proper citation: RRID:RGD_155260364 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=155260365
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2022-10-06)
Alternate IDs: 155260365
Notes: This project entailed generation of a novel rat strain in which a P2A-Cas9-T2A-EGFP coding sequence was inserted at the stop codon of the rat Sycp1 gene for co-expression of Cas9 and EGFP under the control of the Sycp1 regulatory elements. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin
URL: Doi:10.1101/2022.08.30.505951 Donated to Rat Resource & Research Center
Proper citation: RRID:RGD_155260365 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=329955364
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 329955364
Notes: Transgene insertion (human CD68-GFP) using Sleeping Beauty transposon system on Wistar Kyoto rats. Rat monocyte/macrophage reporter strain on a WKY background which has susceptibility to experimental glomerulonephritis. GFP expression occurs exclusively within blood monocytes and tissue macrophages.
Proper citation: RRID:RGD_329955364 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=404976872
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2024-03-18)
Alternate IDs: 404976872
Notes: CD-Tg(RNECO-180E22)733Arno, RGD:155663367 was backcrossed at the Medical College of Wisconsin to DA/MolTacMcwi for 6-7 generations before cryopreservation of sperm. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_404976872 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092606
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092606
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092606 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154611
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 598154611
Notes: The full length humanTOR1A wild type gene including upstream and downstream flanking regions were inserted into a pUC19 vector. Following linearization and purification the transgenes were used to generate transgenic rats by microinjection of the DNA construct into the pronucleus of rat zygotes. Transgenic rats were kept on Sprague–Dawley background and bred as hemizygotes using standard procedures. Genotypes of offspring were determined by PCR and sequencing of DNA extracted from ear biopsies. Primer pair 5′-TAAAAATGTGTATCCGAGTGGAAAT (forward) and 5′-AAGGACTGAGTGTTGTTTCTTTTC (reverse) amplified a 230 bp segment within the coding sequence of exon 5 under the following conditions: 94 °C for 1 min, 60 °C for 1 min and 72 °C for 1 min, 40 cycles. Only lines that showed stable germline transmission of the transgenes were used for further analyses.
Proper citation: RRID:RGD_598154611 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154612
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 598154612
Notes: The 16.25 kbps full length human DYT1 allele of TOR1A gene including upstream and downstream flanking regions were inserted into a pUC19 vector. Following linearization and purification the transgenes were used to generate transgenic rats by microinjection of the DNA construct into the pronucleus of rat zygotes. Transgenic rats were kept on Sprague–Dawley background and bred as hemizygotes using standard procedures. Genotypes of offspring were determined by PCR and sequencing of DNA extracted from ear biopsies. Primer pair 5′-TAAAAATGTGTATCCGAGTGGAAAT (forward) and 5′-AAGGACTGAGTGTTGTTTCTTTTC (reverse) amplified a 230 bp segment within the coding sequence of exon 5 under the following conditions: 94 °C for 1 min, 60 °C for 1 min and 72 °C for 1 min, 40 cycles. Only lines that showed stable germline transmission of the transgenes were used for further analyses.
Proper citation: RRID:RGD_598154612 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092579
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-27)
Alternate IDs: 598092579
Notes: Background strain: Long-Evans rat (Iar:Long-Evans). This strain was established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Tac1 gene) into Long-Evans rat's fertiled eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092579 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405849385
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 405849385
Notes: The hDNMT3A transgenic rats were established using zygote microinjection of a bacterial artificial chromosome (BAC). The RP11-159D24 BAC (NCBI-ID:223335, Homo sapiens, GRCh38.p2: Chr. 2: 25,202,642-25,410,145, total length: 207,504 bp) containing DNMT3A (GRCh38.p2: 25,232,961,25,342,590, total length: 109,630 bp) was injected into rat zygotes (Rattus norvegicus, Sprague-Dawley, SD). The offspring were identified with 8 PCR primer-pairs that were specific for the RP11-159D24 sequence to detect positive transgenic ones.
Proper citation: RRID:RGD_405849385 Copy
Can't find your Organism?
We recommend that you click next to the search bar to check some helpful tips on searches and refine your search firstly. If you want to find a specific organism, it's easier to enter an RRID or a Catalog Number to search. You can refine the search results using Facets on the left side of the search results page. If you are on the table view, you can also search in a specific column by clicking the column title and enter the keywords.
If you still could not find your organism in the search results, please help us by registering it into the system — it's easy. Organisms identifiers are registered through multiple sources depending on the species:
Welcome to the dkNET Resources search. From here you can search through a compilation of resources used by dkNET and see how data is organized within our community.
You are currently on the Community Resources tab looking through categories and sources that dkNET has compiled. You can navigate through those categories from here or change to a different tab to execute your search through. Each tab gives a different perspective on data.
If you have an account on dkNET then you can log in from here to get additional features in dkNET such as Collections, Saved Searches, and managing Resources.
Here is the search term that is being executed, you can type in anything you want to search for. Some tips to help searching:
You can save any searches you perform for quick access to later from here.
We recognized your search term and included synonyms and inferred terms along side your term to help get the data you are looking for.
If you are logged into dkNET you can add data records to your collections to create custom spreadsheets across multiple sources of data.
Here are the sources that were queried against in your search that you can investigate further.
Here are the categories present within dkNET that you can filter your data on
Here are the subcategories present within this category that you can filter your data on
If you have any further questions please check out our FAQs Page to ask questions and see our tutorials. Click this button to view this tutorial again.
The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
Email: info_at_ dknet.org
