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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062917
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004479(rps-10)|WBGene00006753(unc-14)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004479(rps-10), WBGene00006753(unc-14)
Availability: unknown
Source References: EMPTY
Synonyms: rps-10(cc2557)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I.
Notes: Balancer recombination happens frequently at 23-25C, strain must be maintained at 16-20C. Homozygous lethal mutation balanced by Dpy- and myo-2p::Venus-marked inversion. Heterozygotes are non-Dpy with relatively dim pharyngeal GFP (Venus) expression, and segregate heterozygous non-Dpy Venus+, non-Venus cc2557 homozygotes (L1 arrest), and Dpy with brighter Venus+ (tmC20 homozygotes). Pick wild-type Venus(+) and check for proper segregation of progeny to maintain. cc2557 is an engineered mutation creating an early stop (T8*). Presumptive rps-10 null. Heterozygous rps-10(cc2557)/tmC20 animals are delayed in development. Reference: Cenik ES, et al. Dev Cell. 2019 Mar 25;48(6):811-826.e6. doi: 10.1016/j.devcel.2019.01.019. PMID: 30799226.|"Made_by: Elif Sarinay Cenik & Agustian Surya"
Proper citation: RRID:WB-STRAIN:WBStrain00062917 Copy
http://www.wormbase.org/db/get?name=WBStrain00054650
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00009163(drsh-1)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00009163(drsh-1)
Availability: unknown
Source References: EMPTY
Synonyms: drsh-1(viz43)/tmC18[dpy-5(tmIs1200[myo-2p::mVenus])] I.
Notes: Made_by: J. H. Seemann|"[D943G] substitution mutation in conserved residue within RNAse III domain. Balancer marked with myo-2p::Venus. Pick fertile wild-type (non-Dpy) Venus+ to maintain. drsh-1(viz43) homozygous animals display heterochronic phenotypes beginning at L3/L4 molt and typically burst at the vulva in L4. Heterozygotes are wild-type with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus viz-43 homozygotes, and Dpy Venus+ tmC18 homozygotes. Reference: Barish S, et al. Human Mol Genet. 2022 Aug 25;31(17):2934-2950. doi: 10.1093/hmg/ddac085. PMID: 35405010."
Proper citation: RRID:WB-STRAIN:WBStrain00054650 Copy
http://www.wormbase.org/db/get?name=WBStrain00022479
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00001864(him-5)|WBGene00004077(pop-1)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00001864(him-5), WBGene00004077(pop-1)
Availability: available
Source References: PMID:7585963
Synonyms: pop-1(zu189) dpy-5(e61)/hT1 I; him-5(e1490)/hT1 V.
Alternate IDs: WB-STRAIN:JJ1057, CGC_JJ1057
Notes: Heterozygotes are WT and segregate WT, Dpys which give only dead eggs, mid-larval lethals (hT1 homozygotes), males and dead eggs. Mutation in pop-1 results in the MS blastomere adopting the fate of the E blastomere. pop-1 mutant embryos have twice the amount of wild type gut and only make anterior pharynx. him-5 is outside the region balanced by hT2.|"Mutagen:Tc1 (RW7096)"
Proper citation: RRID:WB-STRAIN:WBStrain00022479 Copy
http://www.wormbase.org/db/get?name=WBStrain00022478
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00003229(mex-3)|WBGene00004078(pos-1)|WBGene00006778(unc-42)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00003229(mex-3), WBGene00004078(pos-1), WBGene00006778(unc-42)
Availability: available
Source References: PMID:9834181
Synonyms: mex-3(zu155) dpy-5(e61)/hT1 I; pos-1(zu148) unc-42(e270)/hT1 V.
Alternate IDs: WB-STRAIN:JJ1014, CGC_JJ1014
Notes: The double heterozygote is WT. WT will segregate WT, DpyUncs, mid-larval lethal (hT1 homozygotes) and dead eggs. The DpyUncs are homozygous for zu155 and zu148 and will segregate only dead embryos; the dead embryos have excess hypodermis and muscle and lack germ cells and intestine.
Proper citation: RRID:WB-STRAIN:WBStrain00022478 Copy
http://www.wormbase.org/db/get?name=WBStrain00022541
Source Database: WormBase (WB)
Affected Genes: WBGene00000036(ace-2)|WBGene00001067(dpy-5)|WBGene00001481(fog-1)|WBGene00006751(unc-11)
Genomic Alteration: WBGene00000036(ace-2), WBGene00001067(dpy-5), WBGene00001481(fog-1), WBGene00006751(unc-11)
Availability: available
Source References: EMPTY
Synonyms: fog-1(q372) ace-2(g202) dpy-5(e61)/unc-11(e47) I.
Alternate IDs: WB-STRAIN:JK1153, CGC_JK1153
Notes: Heterozygotes are WT and segregate WT, Dpy Fogs, and Uncs. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00022541 Copy
http://www.wormbase.org/db/get?name=WBStrain00022568
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00006754(unc-15)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00006754(unc-15)
Availability: available
Source References: PMID:9550713
Synonyms: qDf16/dpy-5(e61) unc-15(e1402) I.
Alternate IDs: WB-STRAIN:JK1726, CGC_JK1726
Notes: Heterozygotes are WT and segregate WT, dead eggs and DpyUncs. Maintain by picking WT. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00022568 Copy
http://www.wormbase.org/db/get?name=WBStrain00022586
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00001067(dpy-5)|WBGene00003156(mcm-4)
Genomic Alteration: WBGene00000254(bli-4), WBGene00001067(dpy-5), WBGene00003156(mcm-4)
Availability: available
Source References: EMPTY
Synonyms: mcm-4(e1466) dpy-5(e61) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III).
Alternate IDs: WB-STRAIN:JK2739, CGC_JK2739
Notes: Made_by: K. Siegfried|"qIs48 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter driving GFP in the intestine, and is homozygous lethal. Segregates WT glowing hets, non-glowing sterile Dpys, very rare homozygous hT2 glowing animals, and dead eggs. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype."
Proper citation: RRID:WB-STRAIN:WBStrain00022586 Copy
http://www.wormbase.org/db/get?name=WBStrain00022576
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00001596(gld-2)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00001596(gld-2), WBGene00006752(unc-13)
Availability: available
Source References: EMPTY
Synonyms: gld-2(dx40)/dpy-5(e61) unc-13(e51) I.
Alternate IDs: WB-STRAIN:JK2208, CGC_JK2208
Notes: Segregates wild-type hets, Ste dx40 homozygotes, and Dpy Uncs. Maintain by picking wild-type and checking for correct segregation. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00022576 Copy
http://www.wormbase.org/db/get?name=WBStrain00023694
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002589(let-369)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002589(let-369), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: let-369(h125) dpy-5(e61) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR433, CGC_KR433
Notes: Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in early larval development.
Proper citation: RRID:WB-STRAIN:WBStrain00023694 Copy
http://www.wormbase.org/db/get?name=WBStrain00023695
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002587(let-367)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002587(let-367), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: dpy-5(e61) let-367(h119) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR434, CGC_KR434
Notes: Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h119 arrests as a sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00023695 Copy
http://www.wormbase.org/db/get?name=WBStrain00023693
Source Database: WormBase (WB)
Affected Genes: WBGene00000937(dbr-1)|WBGene00001067(dpy-5)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00000937(dbr-1), WBGene00001067(dpy-5), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: dpy-5(e61) dbr-1(h117) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR432, CGC_KR432
Notes: Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h117 arrests as a early to mid-stage larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00023693 Copy
http://www.wormbase.org/db/get?name=WBStrain00023698
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002719(let-528)|WBGene00003815(nars-1)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002719(let-528), WBGene00003815(nars-1), WBGene00006752(unc-13)
Availability: available
Source References: PMID:1603066
Synonyms: dpy-5(e61) let-528(h1012) nars-1(h106) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR440, CGC_KR440
Notes: Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h1012 arrests as a late larva, and h106 arrests as an early larva; the double arrests as an early larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00023698 Copy
http://www.wormbase.org/db/get?name=WBStrain00023690
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002601(let-381)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002601(let-381), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: dpy-5(e61) let-381(h107) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR429, CGC_KR429
Notes: Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h107 arrests as an embryo or early larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00023690 Copy
http://www.wormbase.org/db/get?name=WBStrain00023691
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002989(lim-7)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002989(lim-7), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: dpy-5(e61) lim-7(h110) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR430, CGC_KR430
Notes: Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in early larval development.
Proper citation: RRID:WB-STRAIN:WBStrain00023691 Copy
http://www.wormbase.org/db/get?name=WBStrain00023689
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002134(inx-12)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002134(inx-12), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: inx-12(h121) dpy-5(e61) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR428, CGC_KR428
Notes: Animals with the Dup are Unc.Animals which have lost the Dup are DpyUnc and arrest in early larval development.
Proper citation: RRID:WB-STRAIN:WBStrain00023689 Copy
http://www.wormbase.org/db/get?name=WBStrain00023683
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002607(let-387)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002607(let-387), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: dpy-5(e61) let-387(h87) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR363, CGC_KR363
Notes: Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h87 arrests as a mid-late larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00023683 Copy
http://www.wormbase.org/db/get?name=WBStrain00023682
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002608(let-388)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002608(let-388), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: dpy-5(e61) let-388(h88) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR362, CGC_KR362
Notes: Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h88 arrests as an early larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00023682 Copy
http://www.wormbase.org/db/get?name=WBStrain00023688
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002591(let-371)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002591(let-371), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: let-371(h123) dpy-5(e61) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR427, CGC_KR427
Notes: Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in mid-late larval development.
Proper citation: RRID:WB-STRAIN:WBStrain00023688 Copy
http://www.wormbase.org/db/get?name=WBStrain00023685
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00004775(sep-1)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00004775(sep-1), WBGene00006752(unc-13)
Availability: available
Source References: WBPaper00000975(PMID:EMPTY)
Synonyms: sep-1(h108) dpy-5(e61) unc-13(e450) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:KR423, CGC_KR423
Notes: Animals with the duplication are Unc. Animals which have lost the duplication are DpyUncLet.
Proper citation: RRID:WB-STRAIN:WBStrain00023685 Copy
http://www.wormbase.org/db/get?name=WBStrain00023658
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00006752(unc-13)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-5(e61) unc-13(e450)I; sDp2(I;f).
Alternate IDs: WB-STRAIN:KR236
Notes: Growth characteristics: Both Unc-13 and Dpy-5 Unc-13 animals are slow growing (generation time at 20C nearly 5 days). Animals carrying two copies of sDp2 have never been recovered.|"Handling: sDp2-bearing males mate and give some progeny, but are slow growing and do not compete well with non-Dp males in mating."|"Segregates: Unc-13, Dpy-5 Unc-13."
Proper citation: RRID:WB-STRAIN:WBStrain00023658 Copy
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