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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Resource Report Resource Website 1+ mentions |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center (RRID:SCR_015315) | data or information resource, access service resource, resource, portal, topical portal, service resource, disease-related portal | Center for research in polycystic kidney disease (PKD) with collaboration by international investigators. The center has several cores, including biomedical cores for antibody validation and cell cultures, educationa programs, and pilot programs for new projects. | polycystic kidney disease, pkd, kidney disease research |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA is parent organization of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering is parent organization of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource is parent organization of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core is parent organization of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank has organization facet: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core has organization facet: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank has organization facet: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering has organization facet: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015315 | 2026-08-10 09:35:18 | 1 | ||||||||
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Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core Resource Report Resource Website |
Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core (RRID:SCR_015304) | core facility, resource, access service resource, service resource | Core provides semiautomated MRI and computed tomography (CT) image and volumetric analyses of polycystic kidneys and liver as well as functional assessment of the kidney and heart, including measurements of renal blood flow. It also facilitates the transmission, collection and storage of anonymized imaging data used in translational PKD research and provides a system that enables PKD researchers to exchange images. | human imaging, data management |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic Minnesota; Minnesota; USA has parent organization: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester is organization facet of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester |
Polycystic Kidney Disease | NIDDK P30DK090728 | Available to the research community | SCR_015304 | 2026-08-10 09:35:27 | 0 | ||||||||
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Polycystic Kidney Disease Research and Translation Centers Resource Report Resource Website |
Polycystic Kidney Disease Research and Translation Centers (RRID:SCR_015305) | data or information resource, topical portal, disease-related portal, portal | A portal with detailed information about various research centers that focus on kidney disease and translational research funded by NIDDK. | online portal, kidney disease research, renal disease, renal physiology |
is listed by: NIDDK Information Network (dkNET) is affiliated with: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is related to: Polycystic Kidney Disease Research Resource Consortium |
Polycystic Kidney Disease | NIDDK P30RFA-DK14-013 | Available to the research community | https://www.pkd-rrc.org/ | SCR_015305 | 2026-08-10 09:35:18 | 0 | |||||||
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Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Resource Report Resource Website |
Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester (RRID:SCR_015313) | data or information resource, access service resource, resource, portal, topical portal, service resource, disease-related portal | Center that concentrates on the common, adult form of the disease, autosomal dominant PKD (ADPKD). The services provided focus on understanding the genetic basis of disease, more accurately monitoring disease progression and improving prognostics, and employing model systems to explore pathogenesis and conduct preclinical testing. | polycystic kidney disease, pathogenesis, preclinical testing |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic Minnesota; Minnesota; USA is parent organization of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core is parent organization of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core is parent organization of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core has organization facet: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core has organization facet: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core has organization facet: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core |
Polycystic Kidney Disease | NIDDK P30DK090728 | Available to the research community | SCR_015313 | 2026-08-10 09:35:27 | 0 | ||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource (RRID:SCR_015291) | core facility, resource, access service resource, service resource | Core facility that provides clinical applications and methods to make kidney research translational and applicable to care settings. | pkd, polycystic kidney disease, clinical research, translational research |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015291 | 2026-08-10 09:35:18 | 0 | ||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core (RRID:SCR_015318) | core facility, resource, access service resource, service resource | Core which supports the work of the Baltimore Polycystic Kidney Disease research center by providing antibody validation services and vectors to researchers. | pkd, polycystic kidney disease, antibody validation |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community, Fee for service | SCR_015318 | 2026-08-10 09:35:18 | 0 | ||||||||
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Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease Resource Report Resource Website 1+ mentions |
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (RRID:SCR_000690) | CRISP | resource, clinical trial | A five-year prospective cohort study following 240 patients who have autosomal-dominant polycystic kidney disease (PKD) to determine whether changes in anatomic characteristics of their kidneys as measured by magnetic resonance imaging will be useful in providing surrogate measures for disease progression. CRISP's overall goal is to develop methods that would facilitate shortening the observation period necessary to determine efficacy of treatment interventions in PKD patients. Specific goals of this study are to: * Quantify cyst growth and ascertain severity of renal parenchymal involvement by sequential measurement of total kidney volume and the ratio of intact parenchyma to renal parenchyma occupied by cysts over time * Establish useful clinical correlations of imaging data with other markers of disease progression * Identify and test other potential markers or indices of disease progression, for example, assessment of loss of heterozygosity of renal cells shed in the urine, or other markers, in cohorts of patients with PKD * Gain information about the cost-effectiveness, patient acceptability, and advantages and disadvantages of different imaging techniques used serially in patients with PKD. Some experience has been gained in establishing that repeat imaging of the same PKD patient, using these techniques, yields reproducible estimates of kidney size and the proportion of renal parenchyma occupied by cysts. MRI may also have the advantage of permitting simultaneous estimation of GFR. Ultrasound has the advantage of being more cost-effective and perhaps more acceptable to patients for repetitive studies, but the measurements may be less accurate and reproducible. Nonetheless, there is very limited experience in applying these techniques to follow progression of the renal disease. Development of improved, reproducible imaging methods that assess cyst growth and provide markers of disease progression could markedly improve the feasibility of clinical trials. Participating clinical centers are Emory University, the Mayo Clinic, University of Kansas, and the University of Alabama at Birmingham. The data coordinating and imaging analysis center is at Washington University. (PI has since moved to University of Pittsburgh) The study found that kidney enlargement resulting from the expansion of cysts is continuous, quantifiable, and associated with the decline of renal function. Cystic expansion occurs at a consistent rate per individual, although it is heterogeneous in the population, and that larger kidneys are associated with more rapid decrease in renal function. These anatomic characteristics of patient kidneys may provide useful surrogate measures for disease progression, and hence enhance the development of targeted therapies for autosomal dominant PKD. CRISP III is a five-year prospective cohort study to follow ~170 remaining autosomal dominant polycystic kidney disease (ADPKD) patients who were part of the original CRISP cohort study. CRISP III will verify and extend the preliminary observations of CRISP to determine the extent to which quantitative (kidney volume and blood flow, and hepatic and kidney cyst volume) or qualitative (cyst distribution and character) structural parameters predict renal insufficiency and develop and test new metrics to quantify and monitor disease progression. Urine metabolites and the genome will be correlated with the progression of disease to look for new, predictive disease biomarkers. This information from CRISP III will help determine if the kidney enlargement, blood flow, cyst distribution, or urine metabolites can function as an informative surrogate measure for disease progression. | mri, kidney volume, cyst volume, kidney, renal function, disease progression, measure, blood flow, hepatic cyst volume, kidney cyst volume, renal insufficiency, urine metabolite, surrogate measure, clinical, intervention |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Pittsburgh; Pennsylvania; USA |
Polycystic kidney disease, Autosomal dominant polycystic kidney disease | NIDDK 5U01DK056961 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_152795 | SCR_000690 | Consortium of Radiologic Imaging Study of PKD | 2026-08-10 09:31:14 | 3 | |||||
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Autosomal Recessive Polycystic Kidney Disease Mutation Database Resource Report Resource Website 10+ mentions |
Autosomal Recessive Polycystic Kidney Disease Mutation Database (RRID:SCR_002290) | data or information resource, data repository, database, service resource, storage service resource | Catalog of all changes detected in PKHD1 (Polycystic Kidney and Hepatic Disease 1) in a locus specific database. Investigators are invited to submit their novel data to this database. These data should be meaningful for clinical practice as well as of relevance for the reader interested in molecular aspects of polycystic kidney disease (PKD). There are also some links and information for ARPKD patients and their parents. Autosomal recessive polycystic kidney disease (ARPKD/PKHD1) is an important cause of renal-related and liver-related morbidity and mortality in childhood. This study reports mutation screening in 90 ARPKD patients and identifies mutations in 110 alleles making up a detection rate of 61%. Thirty-four of the detected mutations have not been reported previously. Two underlying mutations in 40 patients and one mutation in 30 cases are disclosed, and no mutation was detected on the remaining chromosomes. Mutations were found to be scattered throughout the gene without evidence of clustering at specific sites. PKHD1 mutation analysis is a powerful tool to establish the molecular cause of ARPKD in a given family. Direct identification of mutations allows an unequivocal diagnosis and accurate genetic counseling even in families displaying diagnostic challenges. | clinical, gene, genetic, mutation, protein, recessive, renal | has parent organization: RWTH Aachen University; Aachen; Germany | Autosomal recessive polycystic kidney disease, Polycystic kidney disease | PMID:16199545 PMID:11919560 |
Permission required, Terms of use | nif-0000-21038 | http://www.humgen.rwth-aachen.de/index.asp?subform=database.html&nav=database_nav.html | SCR_002290 | Mutation Database Autosomal Recessive Polycystic Kidney Disease (ARPKD/PKHD1) | 2026-08-10 09:31:40 | 14 | |||||
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Polycystic Kidney Disease Research Resource Consortium Resource Report Resource Website 1+ mentions |
Polycystic Kidney Disease Research Resource Consortium (RRID:SCR_022033) | PKD RRC | data or information resource, funding resource, organization portal, portal, consortium | Consortium develops and shares investigative resources, reagents and expertise with broader research community to accelerate innovation and discovery in field of polycystic kidney disease.Provides assistance with protocols and trouble shooting. Provides funding opportunities. | NIDDK, polycystic kidney disease, innovation and discovery, protocols, trouble shooting, funding |
is related to: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is related to: NIDDK Information Network (dkNET) is related to: Polycystic Kidney Disease Research and Translation Centers |
polycystic kidney disease | National Institute of Diabetes and Digestive and Kidney Diseases | Free, Freely available | SCR_022033 | 2026-08-10 09:37:01 | 7 | |||||||
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Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core Resource Report Resource Website |
Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Molecular Genetics and Biomarker Core (RRID:SCR_015308) | core facility, resource, access service resource, service resource | Core services include mutation screening of cell lines derived from ADPKD patients, mutation screening of large, typical ADPKD populations, genetic screening of atypical PKD families, cystic Kidney and Liver Disease Biobank (CKLBB) from ADPKD patients, and urine collection and fractionation. | molecular genetics, biomarker, mutation screening, PKD |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic Minnesota; Minnesota; USA has parent organization: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester is organization facet of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester |
Polycystic Kidney Disease | NIDDK P30DK090728 | Available to the research community | SCR_015308 | 2026-08-10 09:35:18 | 0 | ||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Mouse Models and Biobank (RRID:SCR_015319) | core facility, resource, access service resource, service resource | Core facility which provides mouse models and a biobank of tissues and other materials for research. | pkd, polycystic kidney disease, biobank, mouse model |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015319 | 2026-08-10 09:35:27 | 0 | ||||||||
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Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering Resource Report Resource Website |
Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Cell Culture and Engineering (RRID:SCR_015323) | core facility, resource, access service resource, service resource | Core faiclity that provides researchers with cell culturing and engineering services. | pkd, polycystic kidney disease, cell culture, cell engineering |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Maryland School of Medicine; Maryland; USA has parent organization: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center is organization facet of: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center |
Polycystic Kidney Disease | NIDDK P30DK090868 | Available to the research community | SCR_015323 | 2026-08-10 09:35:18 | 0 | ||||||||
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Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core Resource Report Resource Website |
Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Model Systems Core (RRID:SCR_015312) | core facility, resource, access service resource, service resource | Core that makes available PKD model systems and technologies to PKD researchers at Mayo and at other institutions. Its services include C. elegans PKD-targeted services, Zebrafish PKD-targeted services, and Rodent PKD-targeted services. | model systems, c. elegans, zebrafish, rodents, PKD genes |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic Minnesota; Minnesota; USA has parent organization: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester is organization facet of: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester |
Polycystic Kidney Disease | NIDDK P30DK090728 | Available to the research community | SCR_015312 | 2026-08-10 09:35:18 | 0 | ||||||||
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Renal Disease Portal Resource Report Resource Website |
Renal Disease Portal (RRID:SCR_009030) | Renal Disease Portal | data or information resource, portal, topical portal, data set, disease-related portal | An integrated resource for information on genes, QTLs and strains associated with a variety of kidney and renal system conditions such as Renal Hypertension, Polycystic Kidney Disease and Renal Insufficiency, as well as Kidney Neoplasms. | gene, quantitative trait locus, strain, renal hypertension, kidney neoplasm, phenotype, pathway, biological process, disease, kidney, genome, gviewer, chromosome, molecular function, cellular component, visualization, synteny |
is related to: NIDDK Information Network (dkNET) is related to: Gene Ontology has parent organization: Rat Genome Database (RGD) |
Renal disease, Renal hypertension, Polycystic kidney disease, Renal insufficiency, Kidney neoplasm, Diabetes Insipidus, Hyperoxaluria, Renal hypertension, Nephritis, Nephrocalcinosis, Nephrolithiasis, Nephrosis, Renal Fibrosis, Inborn Error of Renal Tubular Transport, Uremia | nlx_153941 | SCR_009030 | RGD Renal Disease Portal | 2026-08-10 09:33:45 | 0 | |||||||
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HALT PKD Resource Report Resource Website 1+ mentions |
HALT PKD (RRID:SCR_001529) | HALT PKD, HALT-PKD | resource, clinical trial | Consortium established to design and implement clinical trials of treatments that might slow the progressive loss of renal function in Polycystic Kidney Disease (PKD). Two multicenter randomized, double-blind, placebo controlled clinical trials are running concurrently to study the efficacy of renin-angiotensin-aldosterone system blockade on the progression of cystic disease (kidney volume) and on the decline in renal function in autosomal dominant polycystic kidney disease (ADPKD). Study A is to study whether intensive ACE-I/ARB blockade decrease the progression of cystic disease compared to ACE-I monotherapy patients with early disease, relatively preserved renal function, and high-normal BP or hypertension. Study B is to study whether intensive ACE-I/ARB blockade as compared to ACE-I monotherapy slow the decline in kidney function, end-stage of renal disease, or death in the setting of standard blood pressure control in hypertensive patients with moderately advanced disease. | treatment, renal function, lisinopril, placebo, telmisartan, male, female, adolescent, adult human |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA |
Polycystic kidney disease, Autosomal dominant polycystic kidney disease | NIDDK 5U01DK062408 | Free, Freely available | nlx_152832 | https://www.niddkrepository.org/studies/halt-pkd/ | http://www.pkd.wustl.edu/pkdtn/ | SCR_001529 | Polycystic Kidney Disease-Treatment Network | 2026-08-10 09:31:28 | 1 | |||
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PKD Foundation Resource Report Resource Website |
PKD Foundation (RRID:SCR_000209) | nonprofit organization, funding resource | Organization and funder of polycystic kidney disease research to find treatments. The organization also raises awareness for the disease through education, advocacy and support. | funding, polycystic kidney disease, advocacy, awareness, support, education | is related to: Kidney Health Initiative | Polycystic Kidney Disease | Public | nlx_157910 | SCR_000209 | Polycystic Kidney Disease Foundation | 2026-08-09 09:02:55 | 0 |
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The NIDDK Information Network (dkNET) serves the needs of basic and clinical investigators by providing seamless access to large pools of data and research resources relevant to the mission of The National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). dkNET is hosted at University of California San Diego, and is supported by NIH NIDDK grant U24DK097771.
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