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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
PhenoSys
 
Resource Report
Resource Website
10+ mentions
PhenoSys (RRID:SCR_004072) PhenoSys commercial organization A research- and development-oriented company based in Berlin that engineers and markets technology for animal behavior research offering unique, automated instrumentation. This includes specialized applications of virtual reality and touch screen technology for animal behavior environments and RFID (transponder) operated devices in home cage environments. Their experimental systems are used for behavioral phenotyping, brain research, experimental psychology, and the diagnostic characterization of animal models for translational medicine. animal behavior, behavior, virtual reality, learning, memory, cognition, navigation, touchscreen, tracking, emotion, group, group cage, multi-cage, olfactometer, odor, olfactory, sensory, behavioral biology, phenotype nlx_158513 SCR_004072 PhenoSys GmbH 2026-09-05 06:25:14 37
Brain Architecture Project
 
Resource Report
Resource Website
10+ mentions
Brain Architecture Project (RRID:SCR_004283) data or information resource, portal, topical portal Evolving portal that will provide interactive tools and resources to allow researchers, clinicians, and students to discover, analyze, and visualize what is known about the brain's organization, and what the evidence is for that knowledge. This project has a current experimental focus: creating the first brainwide mesoscopic connectivity diagram in the mouse. Related efforts for the human brain currently focus on literature mining and an Online Brain Atlas Reconciliation Tool. The primary goal of the Brain Architecture Project is to assemble available knowledge about the structure of the nervous system, with an ultimate emphasis on the human CNS. Such information is currently scattered in research articles, textbooks, electronic databases and datasets, and even as samples on laboratory shelves. Pooling the knowledge across these heterogeneous materials - even simply getting to know what we know - is a complex challenge that requires an interdisciplinary approach and the contributions and support of the greater community. Their approach can be divided into 4 major thrusts: * Literature Curation and Text Mining * Computational Analysis * Resource Development * Experimental Efforts central nervous system, connectivity, mapping, model, neuroanatomy, organism, post-mortem, structure, nervous system, structure, human, mouse, brain, zebra finch, addiction gene, addiction is used by: BICCN
lists: Allen Institute for Brain Science
lists: University of California at Los Angeles; California; USA
is related to: Mouse Brain Architecture Project
is related to: BICCN Anatomy and Morphology Project
is related to: Allen Institute for Brain Science
has parent organization: Cold Spring Harbor Laboratory
is parent organization of: Human Brain Connectivity Database
is parent organization of: OBART
is parent organization of: Zebrafinch Brain Architecture Project
is parent organization of: Mouse Brain Architecture Project
W. M. Keck Foundation ;
NIMH ;
NIDA ;
Crick-Clay Professorship in Biomathematics at CSHL ;
Mathers Foundation ;
Simons Foundation
Free, Public nlx_143664 SCR_004283 BrainArchitecture.org, BrainArchitecture 2026-09-05 06:25:17 14
Open Connectome Project
 
Resource Report
Resource Website
1+ mentions
Open Connectome Project (RRID:SCR_004232) Open Connectome Project analysis service resource, data access protocol, data analysis service, data or information resource, data repository, data set, image repository, production service resource, service resource, software resource, source code, storage service resource, web service THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 9, 2023. Connectomes repository to facilitate the analysis of connectome data by providing a unified front for connectomics research. With a focus on Electron Microscopy (EM) data and various forms of Magnetic Resonance (MR) data, the project aims to make state-of-the-art neuroscience open to anybody with computer access, regardless of knowledge, training, background, etc. Open science means open to view, play, analyze, contribute, anything. Access to high resolution neuroanatomical images that can be used to explore connectomes and programmatic access to this data for human and machine annotation are provided, with a long-term goal of reconstructing the neural circuits comprising an entire brain. This project aims to bring the most state-of-the-art scientific data in the world to the hands of anybody with internet access, so collectively, we can begin to unravel connectomes. Services: * Data Hosting - Their Bruster (brain-cluster) is large enough to store nearly any modern connectome data set. Contact them to make your data available to others for any purpose, including gaining access to state-of-the-art analysis and machine vision pipelines. * Web Viewing - Collaborative Annotation Toolkit for Massive Amounts of Image Data (CATMAID) is designed to navigate, share and collaboratively annotate massive image data sets of biological specimens. The interface is inspired by Google Maps, enhanced to allow the exploration of 3D image data. View the fork of the code or go directly to view the data. * Volume Cutout Service - RESTful API that enables you to select any arbitrary volume of the 3d database (3ddb), and receive a link to download an HDF5 file (for matlab, C, C++, or C#) or a NumPy pickle (for python). Use some other programming language? Just let them know. * Annotation Database - Spatially co-registered volumetric annotations are compactly stored for efficient queries such as: find all synapses, or which neurons synapse onto this one. Create your own annotations or browse others. *Sample Downloads - In addition to being able to select arbitrary downloads from the datasets, they have also collected a few choice volumes of interest. * Volume Viewer - A web and GPU enabled stand-alone app for viewing volumes at arbitrary cutting planes and zoom levels. The code and program can be downloaded. * Machine Vision Pipeline - They are building a machine vision pipeline that pulls volumes from the 3ddb and outputs neural circuits. - a work in progress. As soon as we have a stable version, it will be released. * Mr. Cap - The Magnetic Resonance Connectome Automated Pipeline (Mr. Cap) is built on JIST/MIPAV for high-throughput estimation of connectomes from diffusion and structural imaging data. * Graph Invariant Computation - Upload your graphs or streamlines, and download some invariants. * iPad App - WholeSlide is an iPad app that accesses utilizes our open data and API to serve images on the go. human, primary visual cortex, data sharing, male, electron microscopy, mri, connectome, annotation, image collection, array tomography is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: CATMAID
is related to: neurodata
is parent organization of: Rambo3D
Johns Hopkins University; Maryland; USA ;
JHU Applied Research Laboratory IRAD ;
JHU Whiting School of Engineering ;
Dean's Award ;
NIBIB 1RO1EB016411-01 (CRCNS);
DARPA N66001-14-1-4028 (GRAPHS);
NSF ACI-1261715;
NSF OCI-1040114;
NIDA 1R01DA036400-01
PMID:23707591 THIS RESOURCE IS NO LONGER IN SERVICE SciRes_000189, nlx_143645 http://openconnecto.me, http://www.nitrc.org/projects/ocp/ SCR_004232 openconnectomeproject, Open Connectome Project: Collectively reverse-engineering the brain one synapse at a time., Open Connectome Project: Collectively reverse-engineering the brain one synapse at a time 2026-09-05 06:25:16 7
dkCOIN
 
Resource Report
Resource Website
1+ mentions
dkCOIN (RRID:SCR_004438) dkCOIN data or information resource, database, resource THIS RESOURCE IS NO LONGER IN SERVICE, documented October 13, 2014. The resource has moved to the NIDDKInformation Network (dkNET) project. Contact them at info_at_dknet.org with any questions. Database of large pools of data relevant to the mission of NIDDKwith the goal of developing a community-based network for integration across disciplines to include the larger DKuniverse of diseases, investigators, and potential users. The focus is on greater use of this data with the objective of adding value by breaking down barriers between sites to facilitate linking of different datasets. To date (2013/06/10), a total of 1,195 resources have been associated with one or more genes. Of 11,580 total genes associated with resources, the ten most represented are associated with 359 distinct resources. The main method by which they currently interconnect resources between the providers is via EntrezGene identifiers. A total of 780 unique genes provide the connectivity between 3,159 resource pairs across consortia. To further increase interconnectivity, the groups have been further annotating their data with additional gene identifiers, publications, and ontology terms from selected Open Biological and Biomedical Ontologies (OBO). gene, adenovirus construct, antibody, co-immunoprecipitation, embryonic stem cell line, functional genomics, histology, mouse strain, pcr primer, protocol, real time pcr, metadata, diabetes, stem cell, metabolism, tissue development, web service, cloud, embryonic stem cell is used by: NIF Data Federation
is related to: Beta Cell Biology Consortium
is related to: NIDDK Information Network (dkNET)
is related to: National Mouse Metabolic Phenotyping Centers
is related to: Nuclear Receptor Signaling Atlas
is related to: Diabetic Complications Consortium
is related to: T1DBase
is related to: OBO
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
NIDDK 3U01DK072473-05S3;
NIDDK 5U24DK076169;
NIDDK U19DK062434
PMID:22734043 THIS RESOURCE IS NO LONGER IN SERVICE nlx_44256 SCR_004438 NIDDKConsortium Interconnectivity Network 2026-09-05 06:25:19 1
WiCell Research Institute
 
Resource Report
Resource Website
100+ mentions
WiCell Research Institute (RRID:SCR_004364) WiCell institution A nonprofit organization offering research and clinical grade pluripotent stem cell lines, cytogenetic testing, quality control testing and cell banking services to researchers worldwide. The organization is focused on enhancing and expanding the study of human pluripotent stem cells by supporting basic research; establishing research protocols; creating and distributing cell lines; providing training to scientists worldwide; and supporting efforts to unlock the therapeutic potential of stem cell technologies. As home to the Wisconsin International Stem Cell (WISC) Bank, and previously the first US National Stem Cell Bank, WiCell serves the worldwide scientific stem cell community through banking, characterization, and distribution of stem cell lines as well as providing technical support. WiCell also offers cytogenetic services, quality control testing services and clinical grade cell lines to researchers across the globe. stem cell, cell line, iinduced pluripotent stem cell is parent organization of: Wisconsin International Stem Cell Bank
is parent organization of: National Stem Cell Bank
Wikidata: Q7997962, ISNI: 0000 0004 0387 4731, grid.439113.d, nlx_38454 https://ror.org/032ycrz75 SCR_004364 2026-09-05 06:25:18 297
Stem Cell Commons
 
Resource Report
Resource Website
1+ mentions
Stem Cell Commons (RRID:SCR_004415) Stem Cell Commons analysis service resource, data or information resource, data repository, data set, database, production service resource, service resource, software resource, source code, storage service resource Open source environment for sharing, processing and analyzing stem cell data bringing together stem cell data sets with tools for curation, dissemination and analysis. Standardization of the analytical approaches will enable researchers to directly compare and integrate their results with experiments and disease models in the Commons. Key features of the Stem Cell Commons * Contains stem cell related experiments * Includes microarray and Next-Generation Sequencing (NGS) data from human, mouse, rat and zebrafish * Data from multiple cell types and disease models * Carefully curated experimental metadata using controlled vocabularies * Export in the Investigation-Study-Assay tabular format (ISA-Tab) that is used by over 30 organizations worldwide * A community oriented resource with public data sets and freely available code in public code repositories such as GitHub Currently in development * Development of Refinery, a novel analysis platform that links Commons data to the Galaxy analytical engine * ChIP-seq analysis pipeline (additional pipelines in development) * Integration of experimental metadata and data files with Galaxy to guide users to choose workflows, parameters, and data sources Stem Cell Commons is based on open source software and is available for download and development. therapeutic target, blood, stem cell, self-renewal, embryonic stem cell, hematopoietic stem cell, leukemia stem cell, gene, protein, phenotype, therapeutic, annotate, share, analyze, data sharing, statistics, visualize, analyze, microarray, next-generation sequencing, statistics, transcription profiling, genome, genome browser, disease model is related to: Galaxy
is related to: ISA Infrastructure for Managing Experimental Metadata
has parent organization: Harvard Stem Cell Institute
Normal, Acute Myelogenous Leukemia, Glioblastoma, Primitive Neuroectodermal Tumor, Etc. PMID:24303302 Open unspecified license nlx_42085 http://bloodprogram.hsci.harvard.edu/ SCR_004415 HSCI Blood Genomics, Harvard Stem Cell Institute Blood Genomics, Harvard Stem Cell Institute Blood Program, HSCI Blood Program 2026-09-05 06:25:19 2
Mouse Brain Architecture Project
 
Resource Report
Resource Website
1+ mentions
Mouse Brain Architecture Project (RRID:SCR_004683) atlas, d spatial image, data or information resource, reference atlas An atlas project whose goal is to enerate brainwide maps of inter-regional neural connectivity that specify the inputs and outputs of every brain region, at a "mesoscopic" level of analysis. A 3D injection viewer is used to view the mouse brain. To determine the outputs of a brain region, anterograde tracers are used which are taken up by neurons locally ("the input"), then transported actively down the axons to the "output regions." The whole brain is then sliced thinly, and each slice is digitally imaged. These 2-D images are reconstructed in 3D. The majority of the resulting 3-D brain image is unlabeled. Only the injected region and its output regions have tracer in them, allowing for identification of this small fraction of the connectivity map. This procedure is repeated identically, to account for individual variability. To determine the inputs to the same brain region as above, a retrograde tracer is injected in the same stereotaxic location ("the input"), and the process is repeated. In order to accumulate data from different mice (each of whom has a slightly different brain shape and size), 3-D spatial normalization is performed using registration algorithms. These gigapixel images of whole-brain sections can be zoomed to show individual neurons and their processes, providing a "virtual microscope." Each sampled brain is represented in about 500 images, each image showing an optical section through a 20 micron-thick slice of brain tissue. A multi-resolution viewer permits users to journey through each brain, following the pathways taken through three-dimensional brain space by tracer-labeled neuronal pathways. A key point is that at the mid-range "mesoscopic" scale, the team expects to assemble a picture of connections that are stereotypical and probably genetically determined in a species-specific manner. By dividing the volume of a hemisphere of the mouse brain into 250 equidistant, predefined grid-points, and administering four different kinds of tracer injections at each grid point -- in different animals of the same sex and age a complete wiring diagram that will be stitched together in "shotgun" fashion from the full dataset. atlas, brain, brain architecture, connectivity, mouse brain architecture, neuroanatomy is related to: Brain Architecture Project
has parent organization: Brain Architecture Project
NIH Office of the Director ;
NIMH RC1MH088659;
NIMH R01MH087988
Fully accessible to the neuroscience community as well as interested members of the general public, Acknowledgement requested nlx_146201 http://www.brainarchitecture.org http://www.brainarchitecture.org/mouse/about SCR_004683 MBA Project, Mouse Brain Architecture 2026-09-05 06:25:22 5
Jackson Laboratory
 
Resource Report
Resource Website
10000+ mentions
Jackson Laboratory (RRID:SCR_004633) JAX institution An independent, nonprofit organization focused on mammalian genetics research to advance human health. Their mission is to discover the genetic basis for preventing, treating, and curing human disease, and to enable research for the global biomedical community. Jackson Laboratory breeds and manages colonies of mice as resources for other research institutions and laboratories, along with providing software and techniques. Jackson Lab also conducts genetic research and provides educational material for various educational levels. genomic, disease, mouse model, human disease, biomaterial manufacture is listed by: One Mind Biospecimen Bank Listing
is affiliated with: Integrative Human Microbiome Project
is related to: ScienceExchange
is related to: Federation of International Mouse Resources
is related to: MGI strains
is related to: One Mind Biospecimen Bank Listing
is related to: Beta Cell Biology Consortium
is related to: Mouse Mutagenesis Center for Developmental Defects
is related to: GenomeMUSter
is parent organization of: Mouse Models For Alzheimer's Disease Research
is parent organization of: Type 1 Diabetes Resource
is parent organization of: MouseCyc
is parent organization of: Special Mouse Strains Resource
is parent organization of: Gene Weaver
is parent organization of: Mouse Phenome Database (MPD)
is parent organization of: Jackson Laboratory Cytogenetic Models Resource
is parent organization of: Parkinson's Disease Mouse Model Resource
is parent organization of: Eye mutant resource - The Jackson Laboratory
is parent organization of: Brainbow mouse resource at Jackson Labs
is parent organization of: Short Course on the Genetics of Addiction
is parent organization of: JAX Cre Repository
is parent organization of: Donate a strain to The Jackson Laboratory Repository
is parent organization of: Jackson Laboratory Neurobiology
is parent organization of: QTL Archive
is parent organization of: Mouse Genome Informatics: The Gene Ontology Project
is parent organization of: Mouse Genome Informatics (MGI)
is parent organization of: Mouse Tumor Biology Database
is parent organization of: Gene Expression Database
is parent organization of: The Jackson Laboratory Hearing Research Program
is parent organization of: JAX Mice: Neural Tube Defects
is parent organization of: JAX Neuroscience Mutagenesis Facility
is parent organization of: Induced Mutant Resource
is parent organization of: Mouse Mutant Resource
is parent organization of: Mouse Genome Database
is parent organization of: Mutant Mouse Resource and Research Center
is parent organization of: eMouseAtlas
is parent organization of: GBRS
is parent organization of: Jackson Laboratory Scientific Instrument Services Core Facility
provides: Knockout Mouse Project Repository
Types 1 diabetes, Type 2 diabetes, Diabetes, Cardiovascular diseases, Metabolic disease, Cancer, Rare disease, Alzheimer's disease, Demantia Available to the research community, Available to the educational community ISNI: 0000 0004 0374 0039, nlx_63162, grid.249880.f, Crossref funder ID: 100005946 https://ror.org/021sy4w91 SCR_004633 JAX Lab, Jackson Lab 2026-09-05 06:25:22 15196
Picky
 
Resource Report
Resource Website
10+ mentions
Picky (RRID:SCR_010963) Picky software resource A software tool for selecting optimal oligonucleotides (oligos) that allows the rapid and efficient determination of gene-specific oligos based on given gene sets, and can be used for large, complex genomes such as human, mouse, or maize. is listed by: OMICtools
has parent organization: Iowa State University; Iowa; USA
NSF DBI0850195 PMID:15180932
PMID:19849862
PMID:20406469
Free, Public, Acknowledgement requested OMICS_00833 SCR_010963 Picky: Optimal Oligonucleotide Design and Analysis 2026-09-05 06:26:51 39
oPOSSUM
 
Resource Report
Resource Website
100+ mentions
oPOSSUM (RRID:SCR_010884) oPOSSUM analysis service resource, data analysis service, production service resource, service resource, software resource A web-based system for the detection of over-represented conserved transcription factor binding sites and binding site combinations in sets of genes or sequences. transcription factor binding site is listed by: OMICtools PMID:22973536
PMID:17576675
PMID:15933209
Acknowledgement requested OMICS_00488 SCR_010884 oPOSSUM-3 2026-09-05 06:26:49 101
Mouse Clinical Institute; Alsace; France
 
Resource Report
Resource Website
10+ mentions
Mouse Clinical Institute; Alsace; France (RRID:SCR_011021) MCI, ICS institution Research infrastructure for generation of new mouse models,being therefore the most important transgenic mouse production unit in France. is related to: AgedBrainSYSBIO ISNI: 0000 0004 0404 8159, nlx_158126, grid.452426.3 https://ror.org/03cjqqq10 SCR_011021 Mouse Clinical Institute, Institut Clinique de la Souris, Institut Clinique de la Souris; Alsace; France 2026-09-05 06:26:52 12
InParanoid: Eukaryotic Ortholog Groups
 
Resource Report
Resource Website
100+ mentions
InParanoid: Eukaryotic Ortholog Groups (RRID:SCR_006801) InParanoid analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Collection of pairwise comparisons between 100 whole genomes generated by a fully automatic method for finding orthologs and in-paralogs between TWO species. Ortholog clusters in the InParanoid are seeded with a two-way best pairwise match, after which an algorithm for adding in-paralogs is applied. The method bypasses multiple alignments and phylogenetic trees, which can be slow and error-prone steps in classical ortholog detection. Still, it robustly detects complex orthologous relationships and assigns confidence values for in-paralogs. The original data sets can be downloaded. protein, ortholog, genome, drosophila pseudoobscura, duplication, entamoeba histolytica, escherichia colik12, eukaryotic, gasterosteus aculeatus, gene, aedes aegypti, apis mellifera, bos taurus, caenorhabditis remanei, candida glabrata, canis familiaris, ciona intestinalis, cryptococcus neoformans, debaromyces hansenii, dictyostelium discoideum, genomic, homolog, inparalog, kluyveromyces lactis, macaca mulatta, monodelphis domestica, orthology, oryza sativa, outparalog, proteome, tetraodon nigroviridis, xenopus tropicalis, blast, proteome, ortholog cluster, cluster, in-paralog, paralog, automatic clustering, genome comparison, FASEB list has parent organization: Stockholm University; Stockholm; Sweden Swedish Research Council ;
Karolinska Institutet; Stockholm; Sweden ;
Pfizer Corporation
PMID:19892828
PMID:18055500
PMID:15608241
PMID:11743721
Acknowledgement requested nif-0000-03024 http://www.cgb.ki.se/inparanoid/ SCR_006801 Inparanoid eukaryotic ortholog database 2026-09-05 06:26:01 189
PeptideAtlas
 
Resource Report
Resource Website
500+ mentions
PeptideAtlas (RRID:SCR_006783) PeptideAtlas data or information resource, data repository, database, service resource, storage service resource Multi-organism, publicly accessible compendium of peptides identified in a large set of tandem mass spectrometry proteomics experiments. Mass spectrometer output files are collected for human, mouse, yeast, and several other organisms, and searched using the latest search engines and protein sequences. All results of sequence and spectral library searching are subsequently processed through the Trans Proteomic Pipeline to derive a probability of correct identification for all results in a uniform manner to insure a high quality database, along with false discovery rates at the whole atlas level. The raw data, search results, and full builds can be downloaded for other uses. All results of sequence searching are processed through PeptideProphet to derive a probability of correct identification for all results in a uniform manner ensuring a high quality database. All peptides are mapped to Ensembl and can be viewed as custom tracks on the Ensembl genome browser. The long term goal of the project is full annotation of eukaryotic genomes through a thorough validation of expressed proteins. The PeptideAtlas provides a method and a framework to accommodate proteome information coming from high-throughput proteomics technologies. The online database administers experimental data in the public domain. You are encouraged to contribute to the database. proteomics, peptide, mass spectrometry, annotation, eukaryotic, genome, peptide sequence, high-throughput mass spectrometry, ensembl, peptideprophet, protein sequence, blood plasma, protein, eukaryotic cell, dna, bio.tools, FASEB list is used by: NIF Data Federation
is used by: ProteomeXchange
is recommended by: NIDDK Information Network (dkNET)
is recommended by: National Library of Medicine
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: Biositemaps
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: Ensembl
is related to: ProteomeXchange
is related to: NIH Data Sharing Repositories
is related to: Integrated Manually Extracted Annotation
has parent organization: Institute for Systems Biology; Washington; USA
NCI ;
NHGRI ;
NIGMS
PMID:20013378
PMID:23215161
PMID:16381952
PMID:15642101
Public, The community can contribute to this resource, Acknowledgement requested nif-0000-03266, r3d100010889, biotools:peptideatlas https://bio.tools/peptideatlas, https://doi.org/10.17616/R3BK61 SCR_006783 Peptide Atlas, PeptideAtlas 2026-09-05 06:26:01 511
Chemical Effects in Biological Systems (CEBS)
 
Resource Report
Resource Website
10+ mentions
Chemical Effects in Biological Systems (CEBS) (RRID:SCR_006778) CEBS data or information resource, data repository, database, service resource, storage service resource Repository for toxicogenomics data, including study design and timeline, clinical chemistry and histopathology findings and microarray and proteomics data. Data derived from studies of chemicals and of genetic alterations, and is compatible with clinical and environmental studies. Data relating to environmental health, pharmacology, and toxicology. It is not necessary to have microarray data, but study design and phenotypic anchoring data are required.CEBS contains raw microarray data collected in accordance with MIAME guidelines and provides tools for data selection, pre-processing and analysis resulting in annotated lists of genes of interest. Biomedical Investigation Database is another component of CEBS system. used to load and curate study data prior to export to CEBS, in addition to capturing and displaying novel data types such as PCR data, or additional fields of interest, including those defined by the HESI Toxicogenomics Committee. BID has been shared with Health Canada and the US Environmental Protection Agency. caenorhabditis elegans, chemical study, microarray, genetic alteration, toxicogenomics, environmental health, study design, timeline, clinical chemistry, histopathology, proteomics, chemical, clinical, microarray hybridization, gel image, phenotype, pharmacology, toxicology is recommended by: National Library of Medicine
has parent organization: National Institute of Environmental Health Sciences
NIEHS ;
NIGMS
PMID:17962311 Free, Freely available nif-0000-02649, r3d100010314 https://doi.org/10.17616/R3W02M SCR_006778 CEBS, Chemical Effects in Biological Systems (CEBS), Chemical Effects in Biological Systems 2026-09-05 06:26:01 19
HAMSTeRS - The Haemophilia A Mutation Structure Test and Resource Site
 
Resource Report
Resource Website
1+ mentions
HAMSTeRS - The Haemophilia A Mutation Structure Test and Resource Site (RRID:SCR_006883) HAMSTeRS, HADB, HADB/HAMSTeRS, HADB / HAMSTeRS data or information resource, data repository, database, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 27, 2019.

Database for those interested in the consequences of Factor VIII genetic variation at the DNA and protein level, it provides access to data on the molecular pathology of haemophilia A. The database presents a review of the structure and function of factor VIII and the molecular genetics of haemophilia A, a real time update of the biostatistics of each parameter in the database, a molecular model of the A1, A2 and A3 domains of the factor VIII protein (based on the crystal structure of caeruloplasmin) and a bulletin board for discussion of issues in the molecular biology of factor VIII. The database is completely updated with easy submission of point mutations, deletions and insertions via e-mail of custom-designed forms. A methods section devoted to mutation detection is available, highlighting issues such as choice of technique and PCR primer sequences. The FVIII structure section now includes a download of a FVIII A domain homology model in Protein Data Bank format and a multiple alignment of the FVIII amino-acid sequences from four species (human, murine, porcine and canine) in addition to the virtual reality simulations, secondary structural data and FVIII animation already available. Finally, to aid navigation across this site, a clickable roadmap of the main features provides easy access to the page desired. Their intention is that continued development and updating of the site shall provide workers in the fields of molecular and structural biology with a one-stop resource site to facilitate FVIII research and education. To submit your mutants to the Haemophilia A Mutation Database email the details. (Refer to Submission Guidelines)
function, gene, genetic, analysis, bioinformatic, biological, biostatistic, caeruloplasmiin, crystal, haemophilia a, human, murine, porcine, canine, level, molecular, molecule, mutation, nucleic acid, or disease- specific databases, pathology, structural, structure, system-, vitromutagenesis, fviii genetic variation, dna, protein, factor viii, blood-clotting protein, point mutation, deletion, insertion has parent organization: Imperial College London; London; United Kingdom Pfizer UK ;
MRC
PMID:9399839
PMID:9016520
PMID:8594555
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21184 http://europium.csc.mrc.ac.uk/WebPages/Main/main.htm, http://hadb.org.uk/ SCR_006883 HAMSTeRS - The Haemophilia A Mutation Structure Test Resource Site, Haemophilia A Mutation Database, Haemophilia A Mutation Structure Test and Resource Site, Haemophilia A Mutation Structure Test Resource Site 2026-09-05 06:26:03 9
Europhenome Mouse Phenotyping Resource
 
Resource Report
Resource Website
10+ mentions
Europhenome Mouse Phenotyping Resource (RRID:SCR_006935) EuroPhenome analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Open source software system for capturing, storing and analyzing raw phenotyping data from SOPs contained in EMPReSS, it provides access to raw and annotated mouse phenotyping data generated from primary pipelines such as EMPReSSlim and secondary procedures from specialist centers. Mutants of interest can be identified by searching the gene or the predicted phenotype. You can also access phenotype data from the EMPReSSlim Pipeline for inbred mouse strains. Initially EuroPhenome was developed within the EUMORPHIA programme to capture and store pilot phenotyping data obtained on four background strains (C57BL/6J, C3H/HeBFeJ, BALB/cByJ and 129/SvPas). EUMORPHIA (European Union Mouse Research for Public Health and Industrial Applications) was a large project comprising of 18 research centers in 8 European countries, with the main focus of the project being the development of novel approaches in phenotyping, mutagenesis and informatics to improve the characterization of mouse models for understanding human molecular physiology and pathology. The current version of EuroPhenome is capturing data from the EUMODIC project as well as the WTSI MGP, HMGU GMC pipeline and the CMHD. EUMODIC is undertaking a primary phenotype assessment of up to 500 mouse mutant lines derived from ES cells developed in the EUCOMM project as well as other lines. Lines showing an interesting phenotype will be subject to a more in depth assessment. EUMODIC is building upon the comprehensive database of standardized phenotyping protocols, called EMPReSS, developed by the EUMORPHIA project. EUMODIC has developed a selection of these screens, called EMPReSSslim, to enable comprehensive, high throughput, primary phenotyping of large numbers of mice. Phenovariants are annotated using a automated pipeline, which assigns a MP term if the mutant data is statistically different to the baseline data. This data is shown in the Phenomap and the mine for a mutant tool. Please note that a statistically significant result and the subsequent MP annotation does not necessarily mean a true phenovariant. There are other factors that could cause this result that have not been accounted for in the analysis. It is the responsibility of the user to download the data and use their expert knowledge or further analysis to decide whether they agree or not. EuroPhenome is primarily based in the bioinformatics group at MRC Harwell. The development of EuroPhenome is in collaboration with the Helmholtz Zentrum Munchen, Germany, the Wellcome Trust Sanger Institute, UK and the Institut Clinique de la Souris, France. phenotype, gene, mutant mouse strain, inbred mouse strain, annotation, ortholog, high-throughput, phenovariant, disorder, c57bl/6j, c3h/hebfej, balb/cbyj, 129/svpas is related to: European Mouse Phenotyping Resource of Standardised Screens
is related to: OMIM
is related to: Understanding Human Disease Through Mouse Genetics
is related to: European Conditional Mouse Mutagenesis Program
is related to: European Mouse Phenotyping Resource of Standardised Screens
has parent organization: MRC Mammalian Genetics Unit
European Union FP6 contract LSHG-CT-2006-037188;
MRC ;
National Genome Research Network
PMID:19933761
PMID:17905814
Open unspecified license, Acknowledgement requested nif-0000-30535 SCR_006935 2026-09-05 06:26:04 19
Scalable Brain Atlas
 
Resource Report
Resource Website
10+ mentions
Scalable Brain Atlas (RRID:SCR_006934) SBA atlas, data or information resource, reference atlas, service resource, software application, software resource A web-based, interactive brain atlas viewer, containing a growing number of atlas templates for various species, including mouse, macaque and human. Standard features include fast brain region lookup, point and click to select a region and view its full 3D extent, mark a stereotaxic coordinate and view all regions in a hierarchy. Built-in extensions are the CoCoMac plugin, which provides a spatial display of Macaque connectivity, and a service to transform stereotaxic coordinates to and from the INCF Waxholm space for the mouse. Three dimensional renderings of brain regions are available through a Matlab interface (local installation of Matlab required). The SBA is designed to be customizable. External users can create plugins, hosted on their own servers, to interactively attach images or data to spatial atlas locations. This fully web-based display engine for brain atlases and topologies allows client websites to show brain region related data in a 3D interactive context. Currently available atlases are: * Macaque: The Paxinos Rhesus Monkey atlas (2000) * Macaque: Various templates available through Caret, registered to F99 space: Felleman and Van Essen (1991), Lewis and Van Essen (2000), Regional Map from K��tter and Wanke (2005), Paxinos Rhesus Monkey (2000) * Macaque: The NeuroMaps Macaque atlas (2008) * Mouse: The INCF Waxholm Space for the mouse (2011). Previous versions available. * Mouse: The Allen Mouse Brain volumetric atlas (ABA07) * Human: The LPBA40 parcellation, registered to SRI24 space A variety of services are being developed around the templates contained in the Scalable Brain Atlas. For example, you can include thumbnails of brain regions in your own webpage. Other applications include: * Analyze atlas templates in Matlab * List all regions belonging to the given template * List of supported atlas templates * Find region by coordinate * Color-coded PNG (bitmap) or SVG (vector) image of a brain atlas slice * Region thumbnail in 2D (slice) or 3D (stack of slices) The Scalable Brain Atlas is created by Rembrandt Bakker and Gleb Bezgin, under supervision of Rolf K��tter in the NeuroPhysiology and -Informatics group of the Donders Institute, Radboud UMC Nijmegen. atlas application, atlas data, image display, javascript, magnetic resonance, os independent, php, three dimensional display, tractography, visualization is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: CoCoMac
is related to: 3DBar
has parent organization: International Neuroinformatics Coordinating Facility
International Neuroinformatics Coordinating Facility GNU General Public License nlx_98156 http://www.nitrc.org/projects/sba SCR_006934 INCF Scalable Brain Atlas 2026-09-05 06:26:04 22
The WWW Virtual Library: Model Organisms
 
Resource Report
Resource Website
The WWW Virtual Library: Model Organisms (RRID:SCR_007007) data or information resource, portal, topical portal Catalog of internet resources relating to biological model organisms, and is part of the Biosciences area of the Virtual Library project. The main Model Organisms Library discussed in this website are: * E. coli (bacterium) * Yeasts (Saccharomyces cerevisiae, and other species) * Dictyostelium discoideum (slime mold) * Drosophila melanogaster (fruit fly) * Xenopus laevis (African clawed frog) Many aspects of biology are similar in most or all organisms, but it is frequently much easier to study particular aspects in particular organisms - for instance, genetics is easier in small organisms that breed quickly, and very difficult in humans! The most popular model organisms have strong advantages for experimental research, and become even more useful when other scientists have already worked on them, discovering techniques, genes and other useful information. bacterium, cerevisiae, model organism, saccharomyces, s. cerevisiae, slime mold, xenopus, catalog, link aggregator is listed by: 3DVC nif-0000-20953 SCR_007007 VL 2026-09-05 06:26:05 0
Mouse Genome Databases
 
Resource Report
Resource Website
1+ mentions
Mouse Genome Databases (RRID:SCR_007147) MGD data or information resource, data set, database, organism-related portal, portal, topical portal A mouse-related portal of genomic databases and tables of mouse brain data. Most files are intended for you to download and use on your own personal computer. Most files are available in generic text format or as FileMaker Pro databases. The server provides data extracted and compiled from: The 2000-2001 Mouse Chromosome Committee Reports, Release 15 of the MIT microsatellite map (Oct 1997), The recombinant inbred strain database of R.W. Elliott (1997) and R. W. Williams (2001), and the Map Manager and text format chromosome maps (Apr 2001). * LXS genotype (Excel file): Updated, revised positions for 330 markers genotyped using a panel of 77 LXS strain. * MIT SNP DATABASE ONLINE: Search and sort the MIT Single Nucleotide Polymorphism (SNP) database ONLINE. These data from the MIT-Whitehead SNP release of December 1999. * INTEGRATED MIT-ROCHE SNP DATABASE in EXCEL and TEXT FORMATS (1-3 MB): Original MIT SNPs merged with the new Roche SNPs. The Excel file has been formatted to illustrate SNP haplotypes and genetic contrasts. Both files are intended for statistical analyses of SNPs and can be used to test a method outlined in a paper by Andrew Grupe, Gary Peltz, and colleagues (Science 291: 1915-1918, 2001). The Excel file includes many useful equations and formatting that will help in navigating through this large database and in testing the in silico mapping method. * Use of inbred strains for the study of individual differences in pain related phenotypes in the mouse: Elissa J. Chesler''s 2002 dissertation, discussing issues relevant to the integration of genomic and phenomic data from standard inbred strains including genetic interactions with laboratory environmental conditions and the use of various in silico inbred strain haplotype based mapping algorithms for QTL analysis. * SNP QTL MAPPER in EXCEL format (572 KB, updated January 2002 by Elissa Chesler): This Excel workbook implements the Grupe et al. mapping method and outputs correlation plots. The main spreadsheet allows you to enter your own strain data and compares them to haplotypes. Be very cautious and skeptical when using this spreadsheet and the technique. Read all of the caveates. This excel version of the method was developed by Elissa Chesler. This updated version (Jan 2002) handles missing data. * MIT SNP Database (tab-delimited text format): This file is suitable for manipulation in statistics and spreadsheet programs (752 KB, Updated June 27, 2001). Data have been formatted in a way that allows rapid acquisition of the new data from the Roche Bioscience SNP database. * MIT SNP Database (FileMaker 5 Version): This is a reformatted version of the MIT Single Nucleotide Polymorphism (SNP) database in FileMaker 5 format. You will need a copy of this application to open the file (Mac and Windows; 992 KB. Updated July 13, 2001 by RW). * Gene Mapping and Map Manager Data Sets: Genetic maps of mouse chromosomes. Now includes a 10th generation advanced intercross consisting of 500 animals genetoyped at 340 markers. Lots of older files on recombinant inbred strains. * The Portable Dictionary of the Mouse Genome, 21,039 loci, 17,912,832 bytes. Includes all 1997-98 Chromosome Committee Reports and MIT Release 15. * FullDict.FMP.sit: The Portable Dictionary of the Mouse Genome. This large FileMaker Pro 3.0/4.0 database has been compressed with StuffIt. The Dictionary of the Mouse Genome contains data from the 1997-98 chromosome committee reports and MIT Whitehead SSLP databases (Release 15). The Dictionary contains information for 21,039 loci. File size = 4846 KB. Updated March 19, 1998. * MIT Microsatellite Database ONLINE: A database of MIT microsatellite loci in the mouse. Use this FileMaker Pro database with OurPrimersDB. MITDB is a subset of the Portable Dictionary of the Mouse Genome. ONLINE. Updated July 12, 2001. * MIT Microsatellite Database: A database of MIT microsatellite loci in the mouse. Use this FileMaker Pro database with OurPrimersDB. MITDB is a subset of the Portable Dictionary of the Mouse Genome. File size = 3.0 MB. Updated March 19, 1998. * OurPrimersDB: A small database of primers. Download this database if you are using numerous MIT primers to map genes in mice. This database should be used in combination with the MITDB as one part of a relational database. File size = 149 KB. Updated March 19, 1998. * Empty copy (clone) of the Portable Dictionary in FileMaker Pro 3.0 format. Download this file and import individual chromosome text files from the table into the database. File size = 231 KB. Updated March 19, 1998. * Chromosome Text Files from the Dictionary: The table lists data on gene loci for individual chromosomes. gene, genetic, chromosome, genotype, inbred mouse strain, pain, phenotype, polygenic, recombinant, trait, genome, genomic, single nucleotide polymorphism, primer, brain, recombinant inbred mouse strain has parent organization: University of Tennessee Health Science Center; Tennessee; USA
is organization facet of: Alliance of Genome Resources
nif-0000-20982 SCR_007147 2026-09-05 06:26:07 2
RTPrimerDB- The Real-Time PCR and Probe Database
 
Resource Report
Resource Website
10+ mentions
RTPrimerDB- The Real-Time PCR and Probe Database (RRID:SCR_007106) RTPrimerDB data or information resource, data repository, database, service resource, storage service resource Database for primer and probe sequences used in real-time PCR assays employing popular chemistries (SYBR Green I, Taqman, Hybridization Probes, Molecular Beacon) to prevent time-consuming primer design and experimental optimization, and to introduce a certain level of uniformity and standardization among different laboratories. Researchers are encouraged to submit their validated primer and probe sequence, so that other users can benefit from their expertise. The database can be queried using the official gene name or symbol, Entrez or Ensembl Gene identifier, SNP identifier, or oligonucleotide sequence. Different options make it possible to restrict a query to a particular application (Gene Expression Quantification/Detection, DNA Copy Number Quantification/Detection, SNP Detection, Mutation Analysis, Fusion Gene Quantification/Detection, Chromatin immunoprecipitation (ChIP)), organism (Human, Mouse, Rat, and others) or detection chemistry. primer, probe, sequence, real-time pcr, gene, assay, real-time pcr assay, FASEB list is listed by: OMICtools
has parent organization: Ghent University; Ghent; Belgium
PMID:18948285
PMID:16381959
PMID:12519963
Public, The community can contribute to this resource nif-0000-03431, OMICS_02322 SCR_007106 2026-09-05 06:26:07 49

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