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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) analysis service resource, production service resource, resource, service resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 Griffin 2026-09-03 04:49:34 21
Sirius Analytical
 
Resource Report
Resource Website
Sirius Analytical (RRID:SCR_003945) Sirius commercial organization Organization that designs and manufactures analytical instrumentation to measure physicochemical parameters for the pharmaceutical and biotech industry, as well as offers physicochemical data and consultancy services. Their instruments provide accurate and reliable values for pKa, log P, log D, solubility and dissolution, particle size and shape analysis. These critical physicochemical parameters are important in drug formulation, and also influence the ability of New Chemical Entities to cross biological membranes such as the gastro-intestinal tract, blood-brain barrier, skin and cell walls. Sirius also offers an analytical service for high quality PhysChem outsourcing, used by hundreds of clients worldwide. measurement, instrument, chemical analysis, physicochemical, drug, small molecule, biotherapeutics, surface imaging, size, shape, drug development is related to: ORBITO nlx_158338 http://www.sirius-analytical.com/ SCR_003945 Sirius - The Science of Measurement, Sirius Analytical Instruments Ltd., Sirius Analytical Ltd 2026-09-03 04:46:48 0
IITC Life Sciences: Plantar Test Apparatus
 
Resource Report
Resource Website
1+ mentions
IITC Life Sciences: Plantar Test Apparatus (RRID:SCR_012152) Plantar Test Apparatus instrument resource The IITC Plantar Analgesia Meter for thermal paw can be used on 12 mice, 6 rats and other animals (cats, rabbits) unrestrained when testing for narcotic drugs. Experiments are easy to perform, simply slide the test head under test subject, align the heat source via our exclusive guide light (idle state) by the attached, adjustable, angled mirror on test head to test subject and perform tests. testing apparatus, hargreaves, paw radiant heat assay, toe toaster, hargreaves method, hardware, instrument, equipment https://drive.google.com/file/d/1b8M9g_eTkJqkJzUFYijHFNj6yW9HLIWa/view?usp=drivesdk rid_000075 https://www.iitcinc.com/pdf/Plantar%20Test%20Hargreaves.pdf SCR_012152 Plantar Test Apparatus for Mice and Rats, Plantar Test Apparatus (Hargreaves Method) for Mice and Rats 2026-09-03 04:51:48 2
Extech: EA15: EasyView Dual Input Temperature Datalogger
 
Resource Report
Resource Website
Extech: EA15: EasyView Dual Input Temperature Datalogger (RRID:SCR_012151) EA15 instrument resource Temperature datalogger compatible with 7 types of thermocouples. This dual input thermometer accepts Types J, K, E, T, R, S, and N thermocouples. RS-232 port to transfer data to PC for analysis (PC software and cable included) data logger, thermocouple, hardware, instrument, equipment Commercial https://drive.google.com/file/d/1a0Hs2SPvnvrkIi3QalcgaLNkG-VmqFmv/view?usp=drivesdk rid_000074 https://www.extech-online.com/index.php?main_page=product_info&cPath=78_21_33&products_id=209 http://www.extech.com/instruments/product.asp?catid=64&prodid=408 SCR_012151 EasyView Dual Input Temperature Datalogger, EA15 thermal data logger 2026-09-03 04:51:30 0
Chemical Methods Ontology
 
Resource Report
Resource Website
1+ mentions
Chemical Methods Ontology (RRID:SCR_003286) CHMO, RSC CMO controlled vocabulary, data or information resource, ontology An ontology that describes methods used to collect data in chemical experiments, such as mass spectrometry and electron microscopy; preparing and separating material for further analysis, such as sample ionization, chromatography, and electrophoresis; and synthesizing materials, such as epitaxy and continuous vapor deposition. It also describes the instruments used in these experiments, such as mass spectrometers and chromatography columns. It is intended to be complementary to the Ontology for Biomedical Investigations (OBI). obo, chemistry, analytical chemistry, physical chemistry, material chemistry, method, health, mass spectrometry, electron microscopy, chemical experiment, sample ionization, chromatography, electrophoresis, instrument is listed by: BioPortal
is listed by: OBO
is listed by: Google Code
is listed by: Ontobee
is related to: Information Artifact Ontology
is related to: Ontology for Biomedical Investigations
has parent organization: Royal Society of Chemistry
Free, Available for download, Freely available nlx_157363 http://purl.bioontology.org/ontology/CHMO, http://purl.obolibrary.org/obo/chmo.owl, http://www.ontobee.org/browser/index.php?o=CHMO https://code.google.com/p/rsc-cmo/ SCR_003286 RSC Chemical Methods Ontology 2026-09-03 04:46:13 1
Fiber Optic Button Response System
 
Resource Report
Resource Website
10+ mentions
Fiber Optic Button Response System (RRID:SCR_009577) instrument resource Instrument that accurately gathers participant responses and verifies signals. The Celeritas Series response units are assembled using high-impact, chemical resistant, medical grade plastic. The response units include a tactile indicator to ensure correct finger placement during experiments and comfortably attach to the participant?s wrists. The units communicate button presses through fiber optic cabling which connects to a Fiber Optic Interface Console located in the control room through an available wave guide. The interface console provides real-time feedback of participant responses via LED indicators and includes a set of switches which can be used to make responses for the participant as needed. eeg, meg, electrocorticography, experiment control, hardware, magnetic resonance, response monitoring, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) https://drive.google.com/file/d/1vvm02GkPgAG6LnRzWE9FEQZD6JSqtngA/view?usp=drivesdk nlx_155759 http://www.nitrc.org/projects/fobrs, https://pstnet.com/wp-content/uploads/2021/04/Celeritas-Operator-Manual.pdf SCR_009577 Celeritas Fiber Optic Response System 2026-09-03 04:50:09 22
Lumina LP- 400 Response System
 
Resource Report
Resource Website
Lumina LP- 400 Response System (RRID:SCR_009596) Lumina LP-400 instrument resource A reliable patient response system designed specifically for use in an fMRI. Lumina was developed to satisfy the requirements of both the clinical and research fields. experiment control, hardware, magnetic resonance, response monitoring, fmri, clinical, research, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) nlx_155789 http://www.nitrc.org/projects/lumina http://www.cedrus.com/ordering/mri/usa.htm SCR_009596 Lumina fMRI Input Device, Lumina LP-400 System for fMRI, Lumina fMRI Response Pad 2026-09-03 04:50:28 0
Brainsight
 
Resource Report
Resource Website
50+ mentions
Brainsight (RRID:SCR_009539) Brainsight resource, software resource Neuronavigation system for use in human cognitive neuroscience (TMS, EEG, NIRS) and for non-human neurosurgical applications. dicom, eeg, eeg, meg, electrocorticography, hardware, minc, minc2, magnetic resonance, nifti, nirs/fnir, optical imaging, optical imaging, philips par/rec, physiological recording, rendering, surface rendering, visualization, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Comercial Licence nlx_155718 http://www.nitrc.org/projects/brainsight SCR_009539 2026-09-03 04:49:58 68
Thermo Fisher: Sartorius: Ambr 15 Cell Culture Generation 2
 
Resource Report
Resource Website
10+ mentions
Thermo Fisher: Sartorius: Ambr 15 Cell Culture Generation 2 (RRID:SCR_013797) instrument resource Automated, high throughput microscale bioreactor system that replicates laboratory scale bioreactor performance., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. instrument, micro bioreactor, ambr, TAP Biosystems, Sartorius, hardware, equipment is related to: Sartorius THIS RESOURCE IS NO LONGER IN SERVICE https://drive.google.com/file/d/1hBdRU27fsVkioRZb_IY_8BGPwIi_2ipq/view?usp=drivesdk https://www.sartorius.com/download/100780/broch-ambr-15-sbi1522-e-1--data.pdf http://www.tapbiosystems.com/a/micro-bioreactor-gp.htm SCR_013797 2026-09-03 04:52:49 45
OEI: fMRI compatible olfactometer
 
Resource Report
Resource Website
1+ mentions
OEI: fMRI compatible olfactometer (RRID:SCR_002507) OEI fMRI compatible olfactometer instrument resource A computerized, odor delivery device that can be used for basic research applications including mapping olfactory centers, cognitive / learning research, neuro-marketing among other uses. Additional products including tests for odor threshold, odor identification, odor discrimination and odor memory. experiment control, hardware, magnetic resonance, stimulus presentation, odor, olfactory, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial License https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_002507.pdf nlx_155907 http://www.nitrc.org/projects/oei, http://www.osmicenterprises.com/docs/OsmicFMRIOlfactomterManual%207-1-13.pdf SCR_002507 2026-09-03 04:45:26 4
SA Instruments: Model 1025 MR-compatible Small Animal Monitoring and Gating System
 
Resource Report
Resource Website
1+ mentions
SA Instruments: Model 1025 MR-compatible Small Animal Monitoring and Gating System (RRID:SCR_002090) Model 1025 Monitoring & Gating System instrument resource Magnetic resonance compatible monitoring and gating system, including software, that enables monitoring rectal temperature, electrocardiogram and respiration rate during magnetic resonance imaging scan time. The PC displays multiple waveforms, measured values, trends and gating pulses. The data Acquisition modules are controlled by menu driven software from the PC. Data acquisition modules are available to measure the following parameters: ECG, respiration (three ways), temperature (two ways), pressure including invasive blood pressure (two ways), oxygen saturation and end-tidal CO2. hardware, instrument, equipment, physiology, monitoring, gating, mr environment, respiration, temperature, blood pressure, oxygen saturation, end-tidal co2, magnetic resonance, electrocardiogram, magnetic resonance imaging, software resource Free, Freely available SciRes_000157 https://wikihost.uib.no/mriwiki/images/4/4c/SAInstruments_1025.pdf http://www.i4sa.com/web_app/main/defaultProduct.aspx?ID=82&PT=3 SCR_002090 Model 1025 Monitoring and Gating System, MR-Compatible Model 1025 Monitoring and Gating System, Small Animal Monitoring and Gating System 2026-09-03 04:45:13 3
Leica: TCS SPE
 
Resource Report
Resource Website
10+ mentions
Leica: TCS SPE (RRID:SCR_002140) TCS SPE instrument resource High resolution, compact and robust confocal that enables immunohistochemical colocalization analysis of florescent markers. Leica TCS SPE confocal point-scanning, spectral system for fluorescence imaging of live or fixed cells. confocal microscope, imaging, instrument, equipment, hardware has parent organization: Leica Microsystems Restricted https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_002140.pdf SciRes_000154 http://www.leica-microsystems.com/fileadmin/downloads/Leica%20TCS%20SPE/Brochures/Leica%20TCS%20SPE-Brochure_EN.pdf SCR_002140 Leica TCS SPE confocal microscope 2026-09-03 04:45:14 33
BD Biosciences: LSR II Flow Cytometer
 
Resource Report
Resource Website
10+ mentions
BD Biosciences: LSR II Flow Cytometer (RRID:SCR_002159) LSR II Flow Cytometer instrument resource Benchtop high-performance cell sorter with multiple lazer, detector and fluoroscrome options. Allows detection of 12 parameters (10 color conjugates, forward and sideward scatter). flow cytometer, instrument, equipment, hardware has parent organization: BD Biosciences THIS RESOURCE IS NO LONGER IN SERVICE https://drive.google.com/file/d/1iqsXa8XNCYWutCswBRYBWluHGag0lOSx/view?usp=drivesdk Model_Number_BD LSR II, SciRes_000152 https://fccf.sitehost.iu.edu/pdf/BDLSRIIUserGuide.pdf http://www.rockefeller.edu/fcrc/pdf/BD_LSRII_Brochure_SJ-0142-00.pdf SCR_002159 2026-09-03 04:45:11 43
COGNISION
 
Resource Report
Resource Website
1+ mentions
COGNISION (RRID:SCR_002362) COGNISION software resource A portable, highly integrated, internet-enabled, hardware / software platform and patient management system, which includes an online Patient Manager module which complies with the HIPAA Final Security Rule, an event-related potential (ERP) Viewer module to view and analyze raw and average ERP waves, and a Protocol Editor module to simplify the choice and administration of selected ERP protocols. It is also easy to train and administer with non-specialized personnel, and is designed to be used in an out-patient setting. COGNISION TM with auditory or visual event-related potential (ERP) technology, provides a direct physiologic measure of patients' cognitive processing (i.e., a cognitive biomarker). eeg, eeg, meg, electrocorticography, event-related potentials, hardware, physiological recording, instrument, equipment is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Commercial License nlx_155724 http://www.nitrc.org/projects/neuronetrix SCR_002362 COGNISION (TM) System 2026-09-03 04:45:23 2
Leica: DMRE Fluorescence Microscope
 
Resource Report
Resource Website
1+ mentions
Leica: DMRE Fluorescence Microscope (RRID:SCR_000011) Leica DMRE microscope instrument resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Microscope that enables bright field and fluorescence imaging options. microscope, fluorescence, imaging, hardware, instrument, equipment, USEDit has parent organization: Leica Microsystems THIS RESOURCE IS NO LONGER IN SERVICE https://drive.google.com/file/d/1wdHpvLSM220N2HdsOjW8rK2mWlPoJEcP/view?usp=drivesdk SciRes_000155 SCR_000011 Fluorescence Leica DMRE microscope 2026-09-03 04:43:00 9
BD Biosciences: FACSAria III Cell Sorter
 
Resource Report
Resource Website
100+ mentions
BD Biosciences: FACSAria III Cell Sorter (RRID:SCR_016695) instrument resource Instrument for cell sorting by BD Biosciences where positive air pressure forces sample cell through an optically gel-coupled cuvette . Hydrodynamic focusing guides particles in a single-file stream through the cuvette, where laser light intercepts the stream at the sample interrogation point.Fluorescence activated cell sorting instrument. Flow cytometer as high speed fixed alignment benchtop cell sorter. Enables multicolor analysis of up to 13 fluorescent markers and two scatter parameters at time. instrument, equipment, USEDit, BD Biosciences, cell, sorter, positive, air, pressure, force, cell, flow is listed by: USEDit Commercially available https://drive.google.com/file/d/14L46Z9kYGpNi6KVjyhP9KmXogSN7q82n/view?usp=drivesdk Model_Number_FACSAria_III https://www.bdbiosciences.com/content/dam/bdb/marketing-documents/BD-FACSAria-III-Cell-Sorter-Brochure.pdf, https://www.bdbiosciences.com/content/dam/bdb/marketing-documents/FACSDiva_Software_Brochure.pdf http://www.bdbiosciences.com/us/instruments/research/cell-sorters/bd-facsaria-iii/m/744763/features SCR_016695 BD FACSARIA III cell sorter, BD FACSARIA III 2026-09-03 04:54:00 106
Leica: CM3050 S Research Cryostat
 
Resource Report
Resource Website
10+ mentions
Leica: CM3050 S Research Cryostat (RRID:SCR_016844) instrument resource Instrument designed for cryosectioning in biomedical, neuro-anatomical and pharmaceutical research. instrument, cryosectioning, biomedical, neuroanatomical, cryostat, Leica, histology, equipment Commercially available https://www.leicabiosystems.com/sites/default/files/media_product-download/2022-01/Leica_CM3050S_IFU_2v4N_en.pdf SCR_016844 Leica CM3050 cryostat 2026-09-03 04:53:57 27
BioNano: Irys system
 
Resource Report
Resource Website
10+ mentions
BioNano: Irys system (RRID:SCR_016754) instrument resource System by BioNano Genomics ( formerly BioNanomatrix) which provides optical next generation mapping (NGM). Used for sequence assembly and structural variation analysis. Provides Scaffold Bionano genome mapping data with sequencing data to improve assembly contiguity, reduce sequencing coverage needed, and automatically correct errors in sequencing based assemblies. instrument, Irys, system, BioNano Genomics, BioNanomatrix, optical, next, generation, mapping, sequence, assembly, structural, variation, analysis, data, Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_016754.pdf https://bionanogenomics.com/wp-content/uploads/2017/01/2016-Irys-System-Brochure.pdf https://bionanogenomics.com/technology/genome-assembly/ SCR_016754 2026-09-03 04:54:12 35
Surface Modified Amperometry CMOS IC
 
Resource Report
Resource Website
1+ mentions
Surface Modified Amperometry CMOS IC (RRID:SCR_017082) instrument resource Integrated circuit device used as tool for amperometry measurement as replacement of conventional carbon fiber microelectrode. Surface modified structures with SU 8 microwells increases life span of each individual device and achieves single cell measurement efficiency by trapping cells inside microwells. instrument, device, CMOS, amperometry, measurement, chip, microelectrode, microwell, cell, semiconductor PMID:28889250 SCR_017082 Surface Modified Amperometry Complementary Metal Oxide Semiconductor IC 2026-09-03 04:54:16 1
Olympus: FluoView FV3000 Confocal Laser Scanning Microscope
 
Resource Report
Resource Website
50+ mentions
Olympus: FluoView FV3000 Confocal Laser Scanning Microscope (RRID:SCR_017015) instrument resource FV3000 is a laser scanning confocal microscope system that captures high-resolution, high-contrast images by scanning samples point by point, enabling precise 3D fluorescence imaging. The system supports inverted and upright configurations and accommodates various objectives with magnifications ranging from 1.25× to 100×, including oil, silicone, and dry lenses, which allows imaging of both macro and micro-scale samples. It is equipped with multiple laser lines for excitation, including 405 nm, 488 nm, 561 nm, and 640 nm, as well as additional lines in some configurations (445 nm, 514 nm, 594 nm, 630 nm), enabling the use of several fluorophores simultaneously. On the detection side, the microscope uses high-sensitivity photomultiplier tube detectors, including GaAsP PMTs and multi-alkali PMTs. instrument, Olympus, confocal, laser, scanning, microscope, Fluoview, FV3000 is used by: Texas State University Nanofabrication Research Service Center Core Facility
is provided by: Olympus
works with: Olympus FV31S-SW software
Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_017015.pdf https://www.olympus-global.com/technology/design/product/fv3000_series.html https://www.olympus-lifescience.com/en/laser-scanning/fv3000 SCR_017015 , Olympus FV3000 Confocal, Olympus FV3000 microscope, FLUOVIEW FV3000 2026-09-03 04:54:14 57

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