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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.youtube.com/user/ASNKidneyTube
ASN Kidney Tube - YouTube are videos hosted at YouTube put out by the American Society of Nephrology (ASN).
Proper citation: ASN Kidney Tube (RRID:SCR_006424) Copy
http://www.kidneycenter.pitt.edu/cores/imaging_core.html
Core that provides qualitative and quantitative image analysis of the kidney and lower urinary tract through performing light and electron microscopic analysis of epithelial cells and tissues, quantifying and reconstructing kidney and lower urinary tract-associated tissues and organs in 3D, and visualizing and quantifying molecular and cellular dynamics in living animals.
Proper citation: Pittsburgh Center for Kidney Research Kidney Imaging (RRID:SCR_015289) Copy
Organization in the U.S. dedicated to the awareness, prevention and treatment of kidney disease. Initiatives include public and professional education, kidney health screenings, research, and patient services. They publish a number of scientific journals including the American Journal of Kidney Diseases, Advances in Chronic Kidney Disease and the Journal of Renal Nutrition. The NKF also publishes the Kidney Dialysis Outcomes Quality Initiative K/DOQI, a comprehensive set of clinical practice guidelines. (Adapted from Wikipedia)
Proper citation: National Kidney Foundation (RRID:SCR_003990) Copy
https://kidneycenter.med.umich.edu/
Center for kidney research at the University of Michigan to assist investigators and clinicians worldwide in kidney disease research. Core services are available to Center researchers to promote their basic, translational and clinical kidney disease research.
Proper citation: University of Michigan Kidney Translational Core Center (RRID:SCR_015903) Copy
Community of patients, caregivers, clinicians, and researchers who perform collaborative studies of kidney stones at pediatric healthcare systems in North America. Network to better understand treatment of kidney stones specifically comparative effectiveness of different surgical approaches to remove kidney stones, impact of these surgeries of patients’ lives, and insight into recovery period.
Proper citation: Pediatric KIDney Stone Care Improvement Network (RRID:SCR_022855) Copy
Educational resource to increase awareness of kidney disease and its risk factors, improve early detection of chronic kidney disease (CKD), reduce the burden of CKD, facilitate identification of patients at greatest risk for progression to kidney failure, stress the importance of testing those at risk, promote evidence-based interventions to slow progression of CKD, and support the coordination of Federal responses to CKD. Target audiences include individuals at risk, particularly those with diabetes, high blood pressure, and a family history of kidney disease, and primary care providers.
Proper citation: National Kidney Disease Education Program (RRID:SCR_006527) Copy
http://www.kidneycenter.pitt.edu/
Center whose focus is to advance knowledge of normal kidney function, cellular mechanisms that contribute to kidney disease, and the myriad altered cellular functions that occur in the setting of renal insufficiency.
Proper citation: Pittsburgh Center for Kidney Research (RRID:SCR_015286) Copy
http://www.dukekidneycenter.org/cores/animal-models-core
Core facility that provides access to a range of experimental models of kidney, heart and vascular diseases. It also provides comprehensive phenotyping services for kidney functions, blood pressure and other cardiovascular functions.
Proper citation: Duke O'Brien Center for Kidney Research Animal Models Core (RRID:SCR_015267) Copy
http://golgi.ana.ed.ac.uk/kidhome.html
The Kidney Development Database was created to collect in one place the data from a large number of developmental studies that have a bearing on the study of kidney development. With its oldest parts dating back to 1993/4, it is, as far as we know, the earliest computer database in the field of vertebrate organogenesis. Data are displayed in tables, arranged according to a standard scheme of kidney development explained in the key. Many of the entries are derived from low-power in situs or published text-only descriptions, and should therefore be interpreted with mild caution.
Proper citation: Kidney Development Database (RRID:SCR_013374) Copy
http://www.dukekidneycenter.org/
Research center which investigates the mechanisms underlying the impact kidney disease has on cardiovascular morbidity and mortality using genetic and basic science approaches.
Proper citation: Duke O'Brien Center for Kidney Research (RRID:SCR_015268) Copy
http://www.kidneycenter.pitt.edu/cores/biostatistics.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented on Feb 16, 2022. Core that offers biostatistical analysis to users of the Pittsburgh Center for Kidney Research. Available to the Pittsburgh Center for Kidney Research community.
Proper citation: Pittsburgh Center for Kidney Research Biostatistical Analysis Services (RRID:SCR_015290) Copy
http://datahub.io/dataset/kupkb/resource/8c1e0082-e958-493b-83e6-111bc1c2f0a5
Ontology describing kidney and urinary pathways cell, anatomy, and disease.
Proper citation: Kidney and Urinary Pathway Ontology (RRID:SCR_006690) Copy
https://public.tableau.com/app/profile/ukkidney/viz/AKIlandingpage/Landingpage
UK Renal Registry collection of data from acute kidney injury patients in England.
Proper citation: Acute Kidney Injury Data Portal (RRID:SCR_024407) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-2ff7-d10c-dacb-da6080000000
The objectives of the physiology core are to establish average values and normal ranges for physiologic parameters of renal function in mice, and to develop novel assays of mouse kidney structure and function. Our goal is to provide valuable institutional and national shared resources to facilitate better understanding of kidney diseases and treatments.
Proper citation: Vanderbilt Mouse Kidney Physiology Core Lab (RRID:SCR_010193) Copy
Center that facilitates translational and clinical research that will advance the prevention and treatment of kidney diseases.
Proper citation: George M. O'Brien Kidney Center at Yale (RRID:SCR_015294) Copy
http://www.baltimorepkdcenter.org/clinical/index.shtml
Core facility that provides clinical applications and methods to make kidney research translational and applicable to care settings.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Clinical and Translational Core Resource (RRID:SCR_015291) Copy
http://www.baltimorepkdcenter.org/antibody/index.shtml
Core which supports the work of the Baltimore Polycystic Kidney Disease research center by providing antibody validation services and vectors to researchers.
Proper citation: Baltimore Polycystic Kidney Disease (PKD) Research and Clinical Core Center Antibody Validation and Vector Core (RRID:SCR_015318) Copy
The Cancer Genomics of the Kidney (CAGEKID) consortium brings together expertise in clinical care and epidemiology with genomic expertise. This consortium is an effort of the larger International Cancer Genome Consortium (ICGC), which has the goal of obtaining a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumour types and/or subtypes with the aim of elucidating the genomic changes present in the many forms of cancers that contribute to the burden of disease throughout the world.
Proper citation: Cancer Genomics of the Kidney (CAGEKID) (RRID:SCR_013670) Copy
http://archives.niddk.nih.gov/patient/crisp/rp-crisp.aspx
A five-year prospective cohort study following 240 patients who have autosomal-dominant polycystic kidney disease (PKD) to determine whether changes in anatomic characteristics of their kidneys as measured by magnetic resonance imaging will be useful in providing surrogate measures for disease progression. CRISP's overall goal is to develop methods that would facilitate shortening the observation period necessary to determine efficacy of treatment interventions in PKD patients. Specific goals of this study are to: * Quantify cyst growth and ascertain severity of renal parenchymal involvement by sequential measurement of total kidney volume and the ratio of intact parenchyma to renal parenchyma occupied by cysts over time * Establish useful clinical correlations of imaging data with other markers of disease progression * Identify and test other potential markers or indices of disease progression, for example, assessment of loss of heterozygosity of renal cells shed in the urine, or other markers, in cohorts of patients with PKD * Gain information about the cost-effectiveness, patient acceptability, and advantages and disadvantages of different imaging techniques used serially in patients with PKD. Some experience has been gained in establishing that repeat imaging of the same PKD patient, using these techniques, yields reproducible estimates of kidney size and the proportion of renal parenchyma occupied by cysts. MRI may also have the advantage of permitting simultaneous estimation of GFR. Ultrasound has the advantage of being more cost-effective and perhaps more acceptable to patients for repetitive studies, but the measurements may be less accurate and reproducible. Nonetheless, there is very limited experience in applying these techniques to follow progression of the renal disease. Development of improved, reproducible imaging methods that assess cyst growth and provide markers of disease progression could markedly improve the feasibility of clinical trials. Participating clinical centers are Emory University, the Mayo Clinic, University of Kansas, and the University of Alabama at Birmingham. The data coordinating and imaging analysis center is at Washington University. (PI has since moved to University of Pittsburgh) The study found that kidney enlargement resulting from the expansion of cysts is continuous, quantifiable, and associated with the decline of renal function. Cystic expansion occurs at a consistent rate per individual, although it is heterogeneous in the population, and that larger kidneys are associated with more rapid decrease in renal function. These anatomic characteristics of patient kidneys may provide useful surrogate measures for disease progression, and hence enhance the development of targeted therapies for autosomal dominant PKD. CRISP III is a five-year prospective cohort study to follow ~170 remaining autosomal dominant polycystic kidney disease (ADPKD) patients who were part of the original CRISP cohort study. CRISP III will verify and extend the preliminary observations of CRISP to determine the extent to which quantitative (kidney volume and blood flow, and hepatic and kidney cyst volume) or qualitative (cyst distribution and character) structural parameters predict renal insufficiency and develop and test new metrics to quantify and monitor disease progression. Urine metabolites and the genome will be correlated with the progression of disease to look for new, predictive disease biomarkers. This information from CRISP III will help determine if the kidney enlargement, blood flow, cyst distribution, or urine metabolites can function as an informative surrogate measure for disease progression.
Proper citation: Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (RRID:SCR_000690) Copy
Core that provides services such as imaging of rodent kidney and heart including functional MRI, processing of tissues for routine paraffin embedding, and single tubule isolation and immunocytochemistry.
Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Cell Biology and Imaging Core (RRID:SCR_015297) Copy
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