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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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GlycoPeptideSearch Resource Report Resource Website |
GlycoPeptideSearch (RRID:SCR_005767) | GPS | software resource | GlycoPeptideSearch (GPS) simplifies data interpretation of N-glycopeptide CID MS/MS datasets by searching for glycopeptide results consistent with MS/MS spectra. Results are tabulated in Excel format. Accelerate and simplify interpretation of N-glycopeptide CID MS/MS spectra using GlycoPeptideSearch (GPS). This tool is designed for tandem mass-spectra acquired from proteolytic digests of purified glycoproteins modified with N-glycans and analyzed by LC-MS/MS and CID. The search yields an Excel spreadsheet of N-glycopeptide matches consistent with the spectra. GPS requires two files as input - an mzXML (or other open spectral format) file of glycopeptide CID tandem mass-spectra and a text file (.txt) of peptide sequences containing the N-linked glycosylation motif NXS/T. Spectral datafiles must be converted from raw vendor formats, such as .RAW or .wiff, to an open peak list format (mzXML preferred). In addition to these two input files, the user must specify one or more glycan databases (provided in the software package). The database(s) selected by the user will be used to match glycan structures in the glycopeptide spectra. The output is an Excel spreadsheet with one or more rows for spectra within the dataset that contain evidence of glycoprotein fragmentation, paired with one or more proposed glycopeptide matches for each spectrum. Glycopeptide matches consist of a peptide-glycan pair, with the peptide drawn from the user-supplied peptide file, and the glycan selected from a glycan database(s). The human subset of the GlycomeDB glycan database is provided, and N-linked glycans are automatically selected from it. GPS interprets glycopeptide CID MS/MS spectra by first requiring MS/MS spectra contain evidence of glycopeptide fragmentation - the oxonium ion peaks (m/z 204 - Hex, m/z 366 - HexNAc), and N-glycopeptide core specific peaks (peptide, peptide + HexNAc, peptide + HexNAc-HexNAc, peptide + HexNAc-HexNAc-Hex). For spectra that meet these initial criteria, for a particular peptide, a mass-based search of one or more glycan databases looks for glycans which capture the remaining mass of the spectral precursor. Additional spectral information may be used to narrow the number of matches, and equivalent glycan topologies may be collapsed to a single peptide-glycan pair. GPS also provides N-glycan compositions with the necessary additional mass, even if no glycan with the composition is present in the glycan database(s). GPS can either be run from the command-line or by using its graphical user interface. We recommend the msconvert (or MSConvertGUI) software from the ProteoWizard project to convert spectral datafiles from vendor formats such as .wiff and .RAW into mzXML. | peptide, glyopeptide, glycoprotein, mass-spectra, ms/ms spectra | has parent organization: Edwards Lab | PMID:22239659 | nlx_149231 | SCR_005767 | 2026-07-25 12:06:09 | 0 | ||||||||
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Finnish Cancer Registry Resource Report Resource Website 1+ mentions |
Finnish Cancer Registry (RRID:SCR_005881) | Finnish Cancer Registry | institution | The Finnish Cancer Registry maintains a nation-wide database on all cancer cases in Finland going back to 1953. It is also an internationally active institute for statistical and epidemiological cancer research. The Mass Screening Registry is a department of the Finnish Cancer Registry, and is responsible of planning and evaluating national cancer screening programs in Finland. The site contains information on cancer research and up to date statistics on the prevalence of different types of cancer in Finland, the Nordic countries and on a global level. The web pages include information for participants in cancer screening and for professionals involved in organizing such screening. | Cancer | Cancer Society of Finland | grid.424339.b, nlx_149446, ISNI: 0000 0000 8634 0612 | https://ror.org/00j15sg62 | SCR_005881 | 2026-07-25 12:06:13 | 8 | ||||||||
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MAGMA Resource Report Resource Website 100+ mentions |
MAGMA (RRID:SCR_005757) | MAGMA | software resource | Software that utilizes a multiobjective evolutionary algorithm for genetic mapping. It is based on a the ECJ evolutionary software package written by Sean Luke and includes the Strength Pareto Evoluationary Algorithm Version 2 changes for multiobjective analysis. The code runs on any platform with Java Version 2. A genetic mapping project, typically implemented during a search for genes responsible for a disease, requires the acquisition of a set of data from each of a large number of individuals. This data set includes the values of multiple genetic markers. These genetic markers occur at discrete positions along the genome, which is a collection of one or more linear chromosomes. Typing the value of a marker in an individual carries a cost; one seeks to minimize the number of markers typed without excessively jeopardizing the probability of detecting an association between a marker and a disease phenotype. MAGMA is a project which employ''s a multiobjective evolutionary algorithm to solve this problem. | gene, genetic mapping, algorithm, genomics, single nucleotide polymorphism, population study, haplotype-block elucidation, java | has parent organization: SourceForge | Juvenile Diabetes Research Foundation | PMID:12875658 | Open unspecified license | nlx_149220 | SCR_005757 | Multiobjective Analyzer for Genetic Marker Acquisition, MAGMA: Multiobjective Analyzer for Genetic Marker Acquisition | 2026-07-25 12:06:11 | 456 | |||||
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Icahn School of Medicine at Mount Sinai; New York; USA Resource Report Resource Website 1+ mentions |
Icahn School of Medicine at Mount Sinai; New York; USA (RRID:SCR_005793) | ISMMS, MSSM | university | Icahn School of Medicine at Mount Sinai, formerly Mount Sinai School of Medicine, is graduate medical school in Manhattan, New York City. Leader in medical and scientific training and education, biomedical research and patient care. | medicine, medical, school, university, doctorate, phd |
uses: Scizzle is affiliated with: BioJupies is related to: Alzheimers Disease Genetics Consortium is related to: Beta Cell Biology Consortium is related to: Clinical and Translational Science Awards Consortium is related to: proMODMatcher is parent organization of: Enrichr is parent organization of: Neuropathology of CTE and Delayed Effects of TBI: Toward In-Vivo Diagnostics is parent organization of: NeuronStudio is parent organization of: Rayburst Open-Source Code is parent organization of: Volume Integration and Alignment System is parent organization of: Volume Integration and Alignment System Source Code is parent organization of: NeuroGL is parent organization of: TIFF Stack Sub-Sampler is parent organization of: Cre-X-Mice: A Database of Cre Transgenic Lines is parent organization of: Mount Sinai School of Medicine: In-Vivo Molecular Imaging Laboratory is parent organization of: Mount Sinai Biobank is parent organization of: ChEA is parent organization of: Kismeth is parent organization of: Lists2Networks is parent organization of: Mount Sianai Department of Neuroscience is parent organization of: NetworKIN is parent organization of: Mount Sinai Alzheimer's Disease Research Center is parent organization of: Manhattan HIV Brain Bank is parent organization of: Computational Neurobiology and Imaging Center is parent organization of: L1000 Characteristic Direction Signature Search Engine is parent organization of: L1000 Fireworks Display is parent organization of: Drug Gene Budger is parent organization of: COVID-19 Crowd Generated Gene and Drug Set Library is parent organization of: GeneOverlap is parent organization of: Datanator is parent organization of: BioSimulations is parent organization of: DE-Sim is parent organization of: Appyters is parent organization of: ezTrack project is parent organization of: Minian is parent organization of: TargetRanger is parent organization of: GeneRanger is parent organization of: Kinase Enrichment Analysis 3 is parent organization of: X2K Web is parent organization of: Diabetes Data and Hypothesis Hub is parent organization of: Icahn School of Medicine at Mount Sinai Microscopy and Advanced Bioimaging Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Transgenic and Genome Editing Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Stem Cell Engineering Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Metabolomics Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Neuropathology Brain Bank and Research CoRE Facility is parent organization of: Icahn School of Medicine at Mount Sinai RNA Nanocore Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Human Immune Monitoring Center Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Center for Advanced Genomics Technology Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Biorepository and Pathology Core Facility is parent organization of: Icahn School of Medicine at Mount Sinai Mount Sinai Cryo-EM CoRE Core Facility |
nlx_55912, grid.59734.3c, Crossref funder ID:100007277, ISNI:0000 0001 0670 2351, Wikidata:Q1950740 | https://ror.org/04a9tmd77 | SCR_005793 | Mount Sinai School of Medicine, Icahn School of Medicine, Icahn School of Medicine at Mount Sinai | 2026-07-25 12:06:12 | 6 | |||||||
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SPLINTER Resource Report Resource Website 10+ mentions |
SPLINTER (RRID:SCR_005826) | SPLINTER | software resource | Software that detects and quantifies short IN/DELs as well as single nucleotide substitutions in pooled-DNA samples. |
is listed by: OMICtools has parent organization: Washington University in St. Louis; Missouri; USA |
Cancer | Free for academic / non-profit use, Commercial use requires license | OMICS_00100 | SCR_005826 | Short IN/DEL Prediction by Large deviation Inference and Non-linear True frequency Estimation by Recursion | 2026-07-25 12:06:09 | 13 | |||||||
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GOEx - Gene Ontology Explorer Resource Report Resource Website 10+ mentions |
GOEx - Gene Ontology Explorer (RRID:SCR_005779) | GOEx | software resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented July 5, 2018. Gene Ontology Explorer (GOEx) combines data from protein fold changes with GO over-representation statistics to help draw conclusions in proteomic experiments. It is tightly integrated within the PatternLab for Proteomics project and, thus, lies within a complete computational environment that provides parsers and pattern recognition tools designed for spectral counting. GOEx offers three independent methods to query data: an interactive directed acyclic graph, a specialist mode where key words can be searched, and an automatic search. A recent hack included in GOEx is to load the sparse matrix index file directly into GOEx, instead of going through the report generation using the AC/T-fold methods. This makes it easy for GOEx to analyze any list of proteins as long as the list follows the index file format (described in manuscript) . Please note that if using this alternative strategy, there will be no protein fold information. Platform: Windows compatible | proteomics, visualization, statistical analysis, gene ontology, parse, pattern recognition, spectral counting, analysis, protein fold |
is listed by: Gene Ontology Tools is related to: Gene Ontology has parent organization: Scripps Research Institute |
CNPq ; CAPES ; FAPERJ BBP grant ; PAPES ; PDTIS ; Ary Frauzino Foundation ; NIAID ; NIH ; genesis molecular biology laboratory ; Fiocruz-INCA collaboration ; NIAID UCSD/MCB0237059; NCRR P41RR011823; NIMH 5R01 MH067880 |
PMID:19239707 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_149249 | http://pcarvalho.com/patternlab/goex.shtml | SCR_005779 | Gene Ontology Explorer, GO Explorer | 2026-07-25 12:06:12 | 26 | ||||
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AppliChem Resource Report Resource Website 1000+ mentions |
AppliChem (RRID:SCR_005814) | commercial organization | An Antibody supplier | nlx_152277 | SCR_005814 | PanReac AppliChem, AppliChem GmbH | 2026-07-25 12:06:10 | 4849 | |||||||||||
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OWLTools Resource Report Resource Website 10+ mentions |
OWLTools (RRID:SCR_005732) | OWLTools | software resource | OWLTools (aka OWL2LS - OWL2 Life Sciences) is a java API for accessing ontologies in either OBO or OWL. OWLTools provides a bio-ontologies friendly wrapper on top of the Manchester OWL API. It provides many features, including: * convenience methods for OBO-like properties such as synonyms, textual definitions, obsoletion, replaced_by * simple graph-like operations over ontologies * visualization using the QuickGO graphs libraries Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible | software library, ontology |
is listed by: Gene Ontology Tools is related to: OBO has parent organization: Gene Ontology has parent organization: Google Project Hosting is parent organization of: OwlSim |
Open unspecified license - Free for academic use | nlx_149192 | SCR_005732 | OWL2LS - OWL2 Life Sciences, OWL Tools | 2026-07-25 12:06:11 | 18 | |||||||
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Blip: Biomedical Logic Programming Resource Report Resource Website 1+ mentions |
Blip: Biomedical Logic Programming (RRID:SCR_005733) | Blip, blipkit | software resource | Biomedical Logical Programming (Blip) is a research-oriented deductive database and prolog application library for handling biological and biomedical data. It includes packages for advanced querying of ontologies and annotations. Blip underpins the Obol tool. Here are some distinguishing characteristics of Blip * Lightweight. Bloat-free: Blip only has as many modules as it needs to do its job. * Fast. * Declarative. Say what you want to do, not how you want to do it * Blip can be Query-oriented: specify your data sources and ask your query * Blip can be Application-oriented: it is designed to be used as an application library used by other bioinformatics tools * Mature and fully functional ontology module for handling both OBO-style ontologies and OWL ontologies. * Modules for handling biological sequences and sequence features. (currently limited functionality, added as needed) * A systems biology module for querying pathway and interaction data. (currently limited functionality, added as needed) * Relational database integration. SQL can be viewed as a highly restricted dialect of Prolog. Although the SWI-Prolog in-memory database is fast and scalable, sometimes it is nice to be able to fetch data from an external database. Blip contains a generic SQL utility module and predicate mappings for the GO database, Ensembl and Chado * Integration with a variety of bioinformatics file formats. SWI-Prolog has a variety of fast libraries for dealing with XML, RDF and tabular data files. Blip provides bridges from bio file formats encoded using these syntaxes into its native models. For other syntaxes, Blip seamlessly integrates other packages such as BioPerl and go-perl. Although these dependencies require extra installation, there is no point reinventing the wheel * Rapid development of web applications. Blip extends SWI-Prolog''''s excellent http support with a simple and powerful logical-functional-programming style application server, serval. This has been used to prototype a fully-featured next-generation replacement for the GO project amigo browser. * Scalable. Blip is not intended to be a toy system on toy data (although it is happy to be used as a toy if you like!). It is intended to be used as an application component and a tool operating on real-world biological and biomedical data Blip is written in SWI-Prolog, a fast, robust and scalable implementation of ISO Prolog. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible | biology, biomedical, ontology, annotation, software library, bioinformatics, module |
is listed by: Gene Ontology Tools is related to: Gene Ontology has parent organization: Berkeley Bioinformatics Open-Source Projects |
GNU Lesser General Public License | nlx_149193 | SCR_005733 | Blip - Biomedical Logic Programming, Biomedical Logical Programming (Blip), Biomedical Logic Programming | 2026-07-25 12:06:08 | 2 | |||||||
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University of Neuchatel; Neuchatel; Switzerland Resource Report Resource Website |
University of Neuchatel; Neuchatel; Switzerland (RRID:SCR_005875) | UniNE | university | French-speaking university based in Neuchâtel, Switzerland. The university has four faculties and more than a dozen institutes, including arts and human sciences, natural sciences, law and economics. | is related to: Pharma-Planta Consortium | grid.10711.36, nlx_158304, ISNI:0000 0001 2297 7718, Crossref funder ID:501100005353, Wikidata:Q541548 | https://ror.org/00vasag41 | SCR_005875 | University of Neuchatel, Universite de Neuchatel, University of Neuch�tel, Universit� de Neuch�tel | 2026-07-25 12:06:11 | 0 | ||||||||
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American Cancer Society Resource Report Resource Website 100+ mentions |
American Cancer Society (RRID:SCR_005756) | ACS | non profit organization | The American Cancer Society is the nationwide, community-based, voluntary health organization dedicated to eliminating cancer as a major health problem by preventing cancer, saving lives, and diminishing suffering from cancer, through research, education, advocacy, and service. Together with our millions of supporters, the American Cancer Society (ACS) saves lives and creates a world with less cancer and more birthdays by helping people stay well, helping people get well, by finding cures, and by fighting back. Headquartered in Atlanta, Georgia, the ACS has 12 chartered Divisions, more than 900 local offices nationwide, and a presence in more than 5,100 communities. | cancer, breast cancer, colon, lung, prostate, skin, breast | Cancer | grid.422418.9, Wikidata: Q463665, nlx_149219, ISNI: 0000 0004 0371 6485, Crossref funder ID: 100000048 | https://ror.org/02e463172 | SCR_005756 | American Cancer Society - The Official Sponsor of Birthdays | 2026-07-25 12:06:09 | 476 | |||||||
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Antigenix America Resource Report Resource Website 1+ mentions |
Antigenix America (RRID:SCR_005871) | commercial organization | An Antibody supplier | nlx_152276 | SCR_005871 | Antigenix America Inc. | 2026-07-25 12:06:11 | 1 | |||||||||||
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ClueGO Resource Report Resource Website 1000+ mentions |
ClueGO (RRID:SCR_005748) | ClueGO | software resource | A Cytoscape plug-in that visualizes the non-redundant biological terms for large clusters of genes in a functionally grouped network. It can be used in combination with GOlorize. The identifiers can be uploaded from a text file or interactively from a network of Cytoscape. The type of identifiers supported can be easily extended by the user. ClueGO performs single cluster analysis and comparison of clusters. From the ontology sources used, the terms are selected by different filter criteria. The related terms which share similar associated genes can be combined to reduce redundancy. The ClueGO network is created with kappa statistics and reflects the relationships between the terms based on the similarity of their associated genes. On the network, the node colour can be switched between functional groups and clusters distribution. ClueGO charts are underlying the specificity and the common aspects of the biological role. The significance of the terms and groups is automatically calculated. ClueGO is easy updatable with the newest files from Gene Ontology and KEGG. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | statistical analysis, function, gene ontology, pathway, annotation, network, plugin, gene |
is listed by: Gene Ontology Tools is listed by: SoftCite is related to: Gene Ontology is related to: Cytoscape is related to: KEGG is related to: BioCarta Pathways has parent organization: National Institute of Health and Medical Research; Rennes; France |
National Institute of Health and Medical Research; Rennes; France ; Ville de Paris ; INCa ; Austrian Ministry for Science and Research ; BINII ; European Union 7FP 202230 |
PMID:19237447 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_149209 | SCR_005748 | 2026-07-25 12:06:11 | 2943 | ||||||
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University of Louisville; Kentucky; USA Resource Report Resource Website 1+ mentions |
University of Louisville; Kentucky; USA (RRID:SCR_005749) | UL | university | Public research university in Louisville, Kentucky. It is part of the Kentucky state university system. |
is parent organization of: University of Louisville Labs and Facilities is parent organization of: University of Louisville Micro/Nano Technology Center is parent organization of: University of Louisville Micro/Nano Technology Center Core Facility is parent organization of: University of Louisville School of Medicine Molecular Modeling Core Facility is parent organization of: University of Louisville Biophysical Core Facility is parent organization of: University of Louisville Medicinal Chemistry Core Facility is parent organization of: University of Louisville Protein Expression and Purification Core Facility is parent organization of: University of Louisville Nuclear Magnetic Resonance Spectroscopy Core Facility is parent organization of: University of Louisville Sequencing Technology Center Genomics Services Core Facility is parent organization of: University of Louisville Proteomics Technology Center PTC Core Facility is parent organization of: University of Louisville KY INBRE Data Science Core Facility is parent organization of: University of Louisville Computing and Research Advanced Computing Core Facility is parent organization of: University of Louisville Micro/Nano Technology Center Bioimaging Core Facility is parent organization of: University of Louisville Micro/Nano Technology Center Imaging and Characterization Core Facility |
Wikidata:Q1317143, grid.266623.5, Crossref funder ID:100007924, nlx_26318, ISNI:0000 0001 2113 1622 | https://ror.org/01ckdn478 | SCR_005749 | UofL, U of L, University of Louisville | 2026-07-25 12:06:08 | 1 | ||||||||
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University of Louisiana; Louisiana; USA Resource Report Resource Website |
University of Louisiana; Louisiana; USA (RRID:SCR_005743) | university | Public research university in Lafayette, Louisiana. It has the largest enrollment within the nine-campus University of Louisiana System and the second largest enrollment in Louisiana. | is parent organization of: New Iberia Research Center | Wikidata:Q116485, grid.266621.7, Crossref funder ID:100008520, ISNI:0000 0000 9831 5270, nlx_12312 | https://ror.org/01x8rc503 | SCR_005743 | 2026-07-25 12:06:08 | 0 | ||||||||||
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Andrew W. Mellon Foundation Resource Report Resource Website 10+ mentions |
Andrew W. Mellon Foundation (RRID:SCR_005864) | Andrew W. Mellon Foundation | funding resource | The Andrew W. Mellon Foundation currently makes grants in five core program areas: * Higher Education and Scholarship * Scholarly Communications and Information Technology * Art History, Conservation, and Museums * Performing Arts * Conservation and the Environment Within each of its core programs, the Foundation concentrates most of its grantmaking in a few areas. Institutions and programs receiving support are often leaders in fields of Foundation activity, but they may also be promising newcomers, or in a position to demonstrate new ways of overcoming obstacles to achieve program goals. Our grantmaking philosophy is to build, strengthen and sustain institutions and their core capacities, rather than be a source for narrowly defined projects. As such, we develop thoughtful, long-term collaborations with grant recipients and invest sufficient funds for an extended period to accomplish the purpose at hand and achieve meaningful results. | grant, higher education, scholarship, scholarly communication, information technology, art history, conservation, museum, performing arts, environment | nlx_149404 | SCR_005864 | 2026-07-25 12:06:13 | 13 | ||||||||||
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American Urological Association Resource Report Resource Website 100+ mentions |
American Urological Association (RRID:SCR_005859) | AUA | institution | The American Urological Association (AUA), founded in 1902, is the premier professional association for the advancement of urologic patient care, and works to ensure that its more than 18,000 members are current on the latest research and practices in urology. The AUA also pursues its mission of fostering the highest standards of urologic care by providing a wide range of servicesincluding publications, research, the Annual Meeting, continuing medical education (CME) and the formulation of health policy. | urology, research |
is listed by: Collaborating for the Advancement of Interdisciplinary Research in Benign Urology is parent organization of: AmerUrological's channel - YouTube |
Urologic disease | grid.422576.0, ISNI: 0000 0001 2222 2235, Wikidata: Q4745327, Crossref funder ID: 100006280, nlx_149398 | https://ror.org/00sbaqa70 | SCR_005859 | American Urological Association (AUA) | 2026-07-25 12:06:10 | 252 | ||||||
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Genome Research Foundation Resource Report Resource Website 1+ mentions |
Genome Research Foundation (RRID:SCR_006056) | GRF, GF | institution | The Genome Foundation (AKA Genome Research Foundation) is a fully government accredited and registered non-profit research foundation. GRF aims to provide genome philosophy, science, and technology. GRF is a nonprofit publisher, and research and advocacy organization to promote completely free publication of knowledge with minimum restriction. Our core objectives are to: * Provide ways to overcome unnecessary barriers to immediate availability, access, and use of research * Pursue a publishing strategy that optimizes the openness, quality, and integrity of the publication process * Develop innovative approaches to the assessment, organization, and reuse of ideas and data Genome Foundation Research * Personalized Medicine * Personal Genomics * AngioGenesis drug * Bioinformatics * RNA expression * Protein structure * Human Genome Rights Projects at Genome Foundation * The Human Genome Rights * Human Genome Rights Petition * Free Personal Genome Sequencing Project * Free Personal Genome Sequencing Petition * Tiger Genome Initiative: Amur Tiger and big cat genomes * Whale Genome Project | bioinformatics, genomics, genome, genome sequencing, personalized medicine, personal genomics, angiogenesis, drug, rna expression, protein structure |
has parent organization: Korean Ministry of Education Science and Technology is parent organization of: MetaBase |
Content is available under BioLicense: the freest license. | grid.410888.d, nlx_151458, Wikidata: Q5533483 | https://ror.org/03khjyh83 | SCR_006056 | Genome Foundation | 2026-07-25 12:06:14 | 1 | ||||||
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ScyTek Laboratories Resource Report Resource Website 100+ mentions |
ScyTek Laboratories (RRID:SCR_005919) | commercial organization | An Antibody supplier | nlx_152455 | SCR_005919 | 2026-07-25 12:06:11 | 109 | ||||||||||||
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MetaQC Resource Report Resource Website 10+ mentions |
MetaQC (RRID:SCR_006000) | software resource | Software for quality control and diagnosis for microarray meta-analysis. Quantitative quality control measures include: (1) internal homogeneity of co-expression structure among studies (internal quality control; IQC); (2) external consistency of co-expression structure correlating with pathway database (external quality control; EQC); (3) accuracy of differentially expressed gene detection (accuracy quality control; AQCg) or pathway identification (AQCp); (4) consistency of differential expression ranking in genes (consistency quality control; CQCg) or pathways (CQCp). For each quality control index, the p-values from statistical hypothesis testing are minus log transformed and PCA biplots were applied to assist visualization and decision. Results generate systematic suggestions to exclude problematic studies in microarray meta-analysis and potentially can be extended to GWAS or other types of genomic meta-analysis. The identified problematic studies can be scrutinized to identify technical and biological causes (e.g. sample size, platform, tissue collection, preprocessing etc) of their bad quality or irreproducibility for final inclusion / exclusion decision. | standalone software, mac os x, unix/linux, windows, r, FASEB list |
is listed by: OMICtools has parent organization: CRAN |
PMID:22116060 | GNU General Public License, v2 | OMICS_04032 | https://github.com/donkang34/MetaQC | SCR_006000 | MetaQC: Objective Quality Control and Inclusion/Exclusion Criteria for Genomic Meta-Analysis, MetaQC: Objective Quality Control and Inclusion / Exclusion Criteria for Genomic Meta-Analysis | 2026-07-25 12:06:15 | 40 |
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