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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://wi.mit.edu/core-facilities/microscopy
Offers guidance and support from the very beginning of project development to data analysis. Offers hands-on, personalized support throughout experimental process including experimental design, instruments training to develop microscopy skills.
Proper citation: Whitehead Institute WM Keck Light Microscopy Innovation Center Core Facility (RRID:SCR_028174) Copy
Facility performs stable isotope analysis and some sample preparation. Analyses include CNS(solid), OH(solid and liquid), DIC(liquids) and CO(solid carbonate, bone, enamel, etc...). Sample prep includes water extractions, soil acidification, grinding, encapsulation, and others.
Proper citation: University of Wyoming Stable Isotope Core Facility (RRID:SCR_028269) Copy
https://mcw.ilab.agilent.com/service_center/show_external/5143/mcw_engineering_core
Core is a specialized team of biomedical engineers dedicated to supporting MCW medical research effort by expertly designing, fabricating, repairing, and calibrating research instrumentation tailored to lab-specific needs. By providing these services in-house at a fraction of the cost of commercial vendors, the Core enables cutting-edge research while maximizing budget efficiency.
Proper citation: Medical College of Wisconsin MCW Engineering Core Facility (RRID:SCR_028303) Copy
https://www.cincinnatichildrens.org/research/shared-facilities/qualitative-methods-analysis/services
Core promotes conduct of high-quality qualitative research with focus on integrating key stakeholder perspectives into research designs. It helps investigators with study design, funding proposals, data collection, and analysis to understand contextual, sociocultural, and experiential factors in health.
Proper citation: Cincinnati Children's Hospital Medical Center Qualitative Methods and Analysis Collaborative Core Facility (RRID:SCR_028231) Copy
https://umaine.edu/core/microscopy/
Core offers tools and technical expertise for research and training in microscopy with both light and electron microscopes. Maintains and operates electron microscopes (SEM with EDS), confocal laser scanning microscope, and tancillary equipment needed for preparation of specimens for EM and other microscopy. Light microscopes encompass optics for bright-field, phase-contrast, Nomarski differential-interference, polarizing, and fluorescence imaging.
Proper citation: University of Maine CORE Electron Microscopy Laboratory Core Facility (RRID:SCR_028245) Copy
https://umaine.edu/core/genetics/
Core offers processing and testing of environmental DNA samples, assay development, field surveys and training services. The equipment housed in the center allows users to receive fluorescence-based qPCR analyses, for quantifying DNA concentration and abundances, and plate preparation.
Proper citation: University of Maine CORE Environmental DNA Laboratory Core Facility (RRID:SCR_028248) Copy
https://umaine.edu/core/cleanroom/
Facility supports micro- and nanoscale fabrication, microsensor development, and atomic-scale materials synthesis. Provides comprehensive technical capabilities, including microlithography (mask aligners, photoresist processing, laser lithography), thin film deposition (e-beam evaporation, sputtering, PECVD, atomic layer deposition), and advanced characterization tools (profilometry, spectroscopic ellipsometry). Fabrication processes are supported by both dry etching (DRIE, RIE) and wet chemical processing (RCA clean, KOH etch, solvent benches), as well as thermal processing systems such as diffusion furnaces and rapid thermal annealing.
Proper citation: University of Maine CORE Microfabrication Cleanroom Core Facility (RRID:SCR_028249) Copy
https://www.gla.ac.uk/schools/cancersciences/research/facilities/cellularanalysis/
Cancer Sciences Flow Cytometry Facility is a joint facility between the School of Cancer Sciences at the University of Glasgow and the CRUK Scotland Institute. Provides access to flow cytometry instrumentation and support from technical experts in analysis and cell sorting.
Proper citation: University of Glasgow Cancer Sciences Flow Cytometry Core Facility (RRID:SCR_028243) Copy
https://www.uwyo.edu/science-initiative/casi/index.html
Core provides instrumentation and service for the University of Wyoming scientific research community. Services include X-ray, Electron Microscopy, and Light microscopy analysis.
Proper citation: University of Wyoming Center for Advanced Scientific Instrumentation CASI Core Facility (RRID:SCR_028293) Copy
https://crn.northwestern.edu/core-facilities/peptide-synthesis-core/
Core offers custom peptide services. Facility provides expertise and instrumentation dedicated to chemical synthesis, purification, and characterization of peptides and peptide materials. Provides standard and catalog peptides, and synthesis of specialty custom peptides modified to fit specific research needs.
Proper citation: Northwestern University Center for Regenerative Nanomedicine Peptide Synthesis Core Facility (RRID:SCR_028279) Copy
https://mcw.ilab.agilent.com/service_center/show_external/4968/cri_imaging_core
Imaging core houses microscopic imaging systems including several confocal microscopes, laser microdissection system and whole slide scanners. Core users will be trained and consulted on instrumentation, software, and analysis.
Proper citation: Medical College of Wisconsin Children’s Research Institute CRI Imaging Core Facility (RRID:SCR_028277) Copy
Core offers high-throughput sequencing, genotyping, single-cell multi-omics, and spatial biology services as well as training and consultation. Next Generation Sequencing (NGS) technologies including Illumina and Element Biosciences short-read sequencing, PacBio and Nanopore long-read sequencing services provide sequencing and library preparation for these platforms. Genotyping is performed on the Fluidigm EP1 System for low to medium assay numbers, genotyping-by-sequencing assays, and with a range of genotyping-by-sequencing technologies (e.g. multiplexed amplicon, single-primer extension, reduced representation, and skim-seq protocols). Gene expression analysis is carried out by RNA-seq on short-read sequencers as well as full-length transcript sequencing on long-read systems. Single-cell transcriptome (high-throughput single-cell gene expression profiling) and multi-ome studies are enabled by our 10X Genomics Chromium X system and Parse Biosciences assays. Spatial transcriptome profiling is supported on the Xenium and Visium HD platforms with the help of our CytAssist instrument for fresh-frozen, fixed-frozen, and FFPE tissue sections. We offer annual Illumina and PacBio sequencing library preparation workshops, free consultations on project considerations and experimental design, and custom sequencing library prep solutions.
Proper citation: University of California Davis DNA Technologies and Expression Analysis Core Facility (RRID:SCR_028316) Copy
https://www.colorado.edu/sharedinstrumentation/biochemistry-nuclear-magnetic-resonance-facility
Facility maintains 400MHz Bruker NMR capable of running NMR experiments, including solution NMR spectroscopy for small molecules, macromolecules, polymers, and proteins. The on-site analytical tools (Topspin, MestRenova) are here to facilitate your research success.
Proper citation: University of Colorado Boulder Biochemistry Nuclear Magnetic Resonance Core Facility (RRID:SCR_028270) Copy
https://histomics.institutducerveau.org
Core offers workspaces and equipment for your histology techniques, as well as advice, training, and services.
Proper citation: Paris Brain Institute Histomics Core Facility (RRID:SCR_028275) Copy
Core offers histological and immunohistochemical services.Our staff includes ASCP certified Histologists and American Board of Pathology certified Pathologists who provide service, assistance, and quality control. Provided services include grossing specimens, frozen and fixed tissue sectioning, routine H&E and specialized histochemical staining, cytospin preparations, IHC/IF and antibody optimizations using investigator provided antibodies. Provides training for immunohistochemical and histochemical techniques.
Proper citation: Medical College of Wisconsin Children's Research Institute Histology Core Facility (RRID:SCR_028288) Copy
Core offers services in the field of bulk, single cell, spatial omics, FACs sorting and sequencing.
Proper citation: University College London Single Cell and Spatial Omics Platform Core Facility (RRID:SCR_028322) Copy
https://www.mayo.edu/research/core-resources/genome-analysis-core/overview
Core provides genomics services including next-generation sequencing, gene expression, and genotyping. It enables studies on human disease mechanisms, cancer, and rare diseases.
Proper citation: Mayo Clinic Genome Analysis Core Facility (RRID:SCR_028327) Copy
https://www.etsmtl.ca/laboratoires/lacime/equipement
Core provides equipment for the fabrication and advanced characterization of cyber-physical microdevices, particularly printed cyber-physical microdevices. Provide students and researchers with environment where engineers receive training with advanced skills in the analog, digital and mixed domains.
Proper citation: ÉTS Montréal LaCIME Scientific Platform Core Facility (RRID:SCR_028326) Copy
https://mcw.ilab.agilent.com/service_center/5692/?tab=about
Core provides guided access to novel technologies for complete dissection of energy flux in rodents and other small animals. Our expert staff assist in development, testing, and standardization of metabolic technologies and workflows to leverage both mouse and rat models of interest. Facility offers 16-cage multiplexed metabolic phenotyping system (Promethion, Sable Systems International) that provides detailed mechanistic dissection of resting metabolic rate (RMR), physical activity, and ingestive behaviors of rodents in home style cage designs across the light cycle. CRMPC combines RMR assessments with direct/combined calorimetry (total heat dissipation) to enable assessment of anaerobic forms of energy expenditure (gut microbiome). Additional services include body composition analysis (via NMR), bone content and density analysis (via DEXA), metabolic caging, indirect calorimetry, bioimpedance spectroscopy, thermal imaging. Staff provide guidance for experimental design, execution of studies, statistical analysis of resulting data, and regulatory assistance and compliance.
Proper citation: Medical College of Wisconsin Comprehensive Rodent Metabolic Phenotyping Core Facility (RRID:SCR_028283) Copy
https://www.roswellpark.org/shared-resources/gene-targeting-transgenic
Core provides investigators in the Western New York area with genetically modified animals for their research through gene targeting and transgenic methodologies.
Proper citation: Roswell Park Comprehensive Cancer Center Gene Targeting and Transgenic Core Facility (RRID:SCR_028287) Copy
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