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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://victorian-bioinformatics-consortium.github.io/degust/
An interactive web tool for visualizing differential gene expression data.
Proper citation: Degust (RRID:SCR_001878) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowUtils.html
Software that provides utilities for flow cytometry data.
Proper citation: flowUtils (RRID:SCR_001879) Copy
https://github.com/hms-dbmi/spp
R analysis and processing package for Illumina platform Chip-Seq data.
Proper citation: SPP (RRID:SCR_001790) Copy
https://github.com/JialiUMassWengLab/TEMP
Software package for detecting transposable elements (TEs) insertions and excisions from pooled high-throughput sequencing data.
Proper citation: TEMP (RRID:SCR_001788) Copy
https://github.com/uci-cbcl/EXTREME
A motif discovery algorithm designed to find DNA-binding motifs in ChIP-Seq and DNase-Seq data.
Proper citation: EXTREME (RRID:SCR_001821) Copy
http://www.megabionet.org/atpid/webfile/
Centralized platform to depict and integrate the information pertaining to protein-protein interaction networks, domain architecture, ortholog information and GO annotation in the Arabidopsis thaliana proteome. The Protein-protein interaction pairs are predicted by integrating several methods with the Naive Baysian Classifier. All other related information curated is manually extracted from published literature and other resources from some expert biologists. You are welcomed to upload your PPI or subcellular localization information or report data errors. Arabidopsis proteins is annotated with information (e.g. functional annotation, subcellular localization, tissue-specific expression, phosphorylation information, SNP phenotype and mutant phenotype, etc.) and interaction qualifications (e.g. transcriptional regulation, complex assembly, functional collaboration, etc.) via further literature text mining and integration of other resources. Meanwhile, the related information is vividly displayed to users through a comprehensive and newly developed display and analytical tools. The system allows the construction of tissue-specific interaction networks with display of canonical pathways.
Proper citation: Arabidopsis thaliana Protein Interactome Database (RRID:SCR_001896) Copy
https://tobiasrausch.com/delly/
Integrated structural variant prediction software that can detect deletions, tandem duplications, inversions and translocations at single-nucleotide resolution in short-read massively parallel sequencing data. It uses paired-ends and split-reads to sensitively and accurately delineate genomic rearrangements throughout genome.
Proper citation: DELLY (RRID:SCR_004603) Copy
http://i.cs.hku.hk/~alse/MetaCluster/
A software for binning and annotating short paired-end reads.
Proper citation: MetaCluster-TA (RRID:SCR_004599) Copy
https://code.google.com/p/tred/
Software tool to visualize and edit phylogenetic trees. It combines a browser-based Javascript client with a Python (web2py) server. Trees are rendered in SVG using Raphael.
Proper citation: tree editor (RRID:SCR_004533) Copy
https://computation-rnd.llnl.gov/lmat/
Open-source software tool to assign taxonomic labels to as many reads as possible in very large metagenomic datasets and report the taxonomic profile of the input sample. The quick "single pass" analysis of every read allows read binning to support additional more computationally expensive analysis such as metagenomic assembly or sensitive database searches on targeted subsets of reads.
Proper citation: LMAT (RRID:SCR_004646) Copy
http://metagenomics.atc.tcs.com/binning/DiScRIBinATE/
Software for accurate taxonomic classification of metagenomic sequences using a similarity based binning method. User needs to perform a similarity search of the input metagenomic sequences (reads) against the nr protein database using BLASTx search. The generated blastx output is then taken as the input by the DiScRIBinATE program.
Proper citation: DiScRIBinATE (RRID:SCR_004862) Copy
http://bergelson.uchicago.edu/software/marta
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Java-based software that blasts each sequence that you provide it, and then looks for a consensus taxon among the top-hits returned from blast. MARTA uses NCBI''s megablast program to align your sequence(s) against a local installation of blast. Then MARTA uses GenInfo Identifiers from the top-hits to retrieve taxonomic information from NCBI''s taxonomy database. Using your thresholds/cutoffs, MARTA ''votes'' to find a taxonomic assignment by consensus; MARTA might resolve some sequences to species level, and others to kingdom or to no level, depending on the taxonomic information held within your tag or sequence.
Proper citation: MARTA (RRID:SCR_004850) Copy
http://metaphyler.cbcb.umd.edu/
A taxonomic classifier for metagenomic shotgun reads, which uses phylogenetic marker genes as a taxonomic reference. The classifier, based on BLAST, uses different thresholds (automatically learned from the reference database) for each combination of taxonomic rank, reference gene, and sequence length. The reference database includes marker genes from all complete genomes, several draft genomes and the NCBI nr protein database.
Proper citation: MetaPhyler (RRID:SCR_004848) Copy
http://bioinformatics.fh-stralsund.de/nucpos/
A simulation tool to identify positions of nucleosomes from Next Generation Sequencing data.
Proper citation: NucPosSimulator (RRID:SCR_004765) Copy
http://huttenhower.sph.harvard.edu/metaphlan2
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Computational tool for profiling the composition of microbial communities from metagenomic shotgun sequencing data. It relies on unique clade-specific marker genes identified from reference genomes.
Proper citation: MetaPhlAn (RRID:SCR_004915) Copy
A collection of software tools for for both low and high level analysis of next generation, ultra high throughput signature sequencing data from the Solexa, SOLiD, and 454 platforms.
Proper citation: USeq (RRID:SCR_004753) Copy
http://blast.ncbi.nlm.nih.gov/Blast.cgi
Web search tool to find regions of similarity between biological sequences. Program compares nucleotide or protein sequences to sequence databases and calculates statistical significance. Used for identifying homologous sequences.
Proper citation: NCBI BLAST (RRID:SCR_004870) Copy
http://compbio.cs.toronto.edu/prism/
Software for split read (reads which span across a structrual variant -- SV ) mapping and SV calling from the mapping result. It is able to detect small insertions and abitrary size deletions, inversions and tandom duplications with the direction of discordant read pairs. PRISM_CTX is a tool for detecting inter-chromosome trans-location events.
Proper citation: PRISM - Pair Read Informed Split Mapper (RRID:SCR_004812) Copy
http://ibis.tau.ac.il/miRNAkey/
A software pipeline for the analysis of microRNA Deep Sequencing data.
Proper citation: miRNAKey (RRID:SCR_004813) Copy
http://svmerge.sourceforge.net/
Software pipeline to detect structural variants (SVs) by integrating calls from several existing SV callers, which are then validated and the breakpoints refined using local de novo assembly. The output is in BED format allowing for easy downstream analysis or viewing in a genome browser. It is modular and extensible allowing new callers to be incorporated as they become available.
Proper citation: SVMerge (RRID:SCR_004777) Copy
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