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http://edwards.sdsu.edu/cgi-bin/prinseq/prinseq.cgi

A publicly available tool that is able to filter, reformat and trim your genomic and metagenomic sequence data and provide you summary statistics for your sequence data. The interactive web interface facilitates visualizations of the results and export functionality for subsequent data processing. The standalone lite version is written in Perl and does not require any non-core Perl modules. The lite version is primarily designed for data preprocessing and does not generate summary statistics in graphical form., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: PRINSEQ (RRID:SCR_005454) Copy   

•   Source: SciCrunch Registry

http://www.tmanavigator.org/

A free web-based service open to all users for analysis of tissue microarray (TMA) data and related information, accommodating categorical, semi-continuous and continuous expression scores. There is no login requirement.

Proper citation: TMA Navigator (RRID:SCR_005599) Copy   

•   Source: SciCrunch Registry

http://array.mbb.yale.edu/analysis/

A fully integrated platform for processing microarray data.

Proper citation: ExpressYourself (RRID:SCR_008881) Copy   

•   Source: SciCrunch Registry

http://wavi.bioinfo.cnio.es/

A versatile web-server application for the analysis and visualization of array-CGH data.

Proper citation: waviCGH (RRID:SCR_006662) Copy   

•   Source: SciCrunch Registry

http://gaa.mpi-bn.mpg.de/

Data analysis service that allows to process CEL files from Affymetrix, Inc. GeneChip Gene 1.0 ST Arrays to identify alternative splicing.

Proper citation: Gene Array Analyzer (RRID:SCR_008323) Copy   

•   Source: SciCrunch Registry

http://cbdb.nimh.nih.gov/microsniper/

A web-based application which predicts the impact of a SNP on putative microRNA targets.

Proper citation: MicroSNiPer (RRID:SCR_009880) Copy   

•   Source: SciCrunch Registry

http://www.imtech.res.in/raghava/bhairpred/

Bhairpred server is based on machine learning technique SVM using single sequence information, evolutionary profile, predicted and observed secondary structure (as obtained using Psipred and DSSP), predicted and observed accessibility values (as obtainned from Netasa and DSSP). The methods were trained and tested on dataset of 2880 proteins and their performance was evaluated on dataset of 534 proteins used by Thornton (PNAS, 2002). Best prediction results were obtained with hybrid approach that combined prediction results from evolutionary profile, predicted secondary structure and accessibility.

Proper citation: SVM based method for predicting beta hairpin structures in proteins (RRID:SCR_008349) Copy   

•   Source: SciCrunch Registry

http://www.medinfopoli.polimi.it/GFINDer/

THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 16, 2019. Multi-database system providing large-scale lists of user-classified sequence identifiers with genome-scale biological information and functional profiles biologically characterizing the different gene classes in the list. GFINDer automatically retrieves updated annotations of several functional categories from different sources, identifies the categories enriched in each class of a user-classified gene list, and calculates statistical significance values for each category. Moreover, GFINDer enables to functionally classify genes according to mined functional categories and to statistically analyze the obtained classifications, aiding in better interpreting microarray experiment results.

Proper citation: GFINDer: Genome Function INtegrated Discoverer (RRID:SCR_008868) Copy   

•   Source: SciCrunch Registry

http://crcview.hegroup.org/

Web-based microarray data analysis and visualization system powered by CRC, or Chinese Restaurant cluster, a Dirichlet process model-based clustering algorithm recently developed by Dr. Steve Qin. It also incorporates several gene expression analysis programs from Bioconductor, including GOStats, genefilter, and Heatplus. CRCView also installs from the Bioconductor system 78 annotation libraries of microarray chips for human (31), mouse (24), rat (14), zebrafish (1), chicken (1), Drosophila (3), Arabidopsis (2), Caenorhabditis elegans (1), and Xenopus Laevis (1). CRCView allows flexible input data format, automated model-based CRC clustering analysis, rich graphical illustration, and integrated Gene Ontology (GO)-based gene enrichment for efficient annotation and interpretation of clustering results. CRC has the following features comparing to other clustering tools: 1) able to infer number of clusters, 2) able to cluster genes displaying time-shifted and/or inverted correlations, 3) able to tolerate missing genotype data and 4) provide confidence measure for clusters generated. You need to register for an account in the system to store your data and analyses. The data and results can be visited again anytime you log in.

Proper citation: CRCView (RRID:SCR_007092) Copy   

•   Source: SciCrunch Registry

http://centre.bioinformatics.zj.cn/mirtools/

A comprehensive web server developed to allow researchers to comprehensively characterize small RNA transcriptome.

Proper citation: mirTools (RRID:SCR_009701) Copy   

•   Source: SciCrunch Registry

http://rulai.cshl.edu/cgi-bin/tools/ESE3/esefinder.cgi?process=home

A web-based resource that facilitates rapid analysis of exon sequences to identify putative exonic splicing enhancers (ESEs) responsive to the human SR proteins SF2/ASF, SC35, SRp40 and SRp55, and to predict whether exonic mutations disrupt such elements.

Proper citation: ESEfinder 3.0 (RRID:SCR_007088) Copy   

•   Source: SciCrunch Registry

http://tcoffee.crg.cat/apps/tcoffee/do:regular

A multiple sequence alignment server which can align Protein, DNA and RNA sequences.

Proper citation: T-Coffee (RRID:SCR_011818) Copy   

•   Source: SciCrunch Registry

http://probcons.stanford.edu/

Efficient protein multiple sequence alignment program, which has demonstrated a statistically significant improvement in accuracy compared to several leading alignment tools.

Proper citation: ProbCons (RRID:SCR_011813) Copy   

•   Source: SciCrunch Registry

http://www.acedb.org/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 6th,2023. Software genome database management system.

Proper citation: AceDB (RRID:SCR_010671) Copy   

•   Source: SciCrunch Registry

http://nhjy.hzau.edu.cn/kech/swxxx/jakj/dianzi/Bioinf6/GeneFinding/GeneFinding2.htm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 10,2020. Data analysis service for Hidden Markov Model (HMM)-based gene structure prediction (multiple genes, both chains).

Proper citation: FGENESH (RRID:SCR_011928) Copy   

•   Source: SciCrunch Registry

http://race.unil.ch/

A collection of web tools designed to assist with the analysis of DNA microarray data and results. RACE performs probe level data preprocessing, quality checks, normalization, and visualization for Affymetrix GeneChips. In addition, it performs clustering and differential analysis of normalized expression levels or ratios for arbitrary platforms, and estimates the false discovery rates in lists of potentially regulated genes. A Gene Ontology (GO)-term analysis assists in the biological interpretation of gene lists. The user can customize each analysis request; upon submission the analysis is executed in a fully automated way., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: RACE (RRID:SCR_010950) Copy   

•   Source: SciCrunch Registry

http://www.imtech.res.in/raghava/hslpred/

A support vector machine (SVM)-based method for the prediction of 4 major subcellular localization (cytoplasm, mitochondrial, nuclear and plasma membrane) of human proteins using various features such as i) amino acid composition, ii) dipeptide composition and iii) evolutionary information of proteins.

Proper citation: HSLPred (RRID:SCR_011972) Copy   

•   Source: SciCrunch Registry

http://159.149.160.51/pscan_chip_dev/

Web server that, starting from a collection of genomic regions derived from a ChIP-Seq experiment, scans them using motif descriptors like JASPAR or TRANSFAC position-specific frequency matrices, or descriptors uploaded by users, and it evaluates both motif enrichment and positional bias within the regions according to different measures and criteria.

Proper citation: Pscan-ChIP (RRID:SCR_010885) Copy   

•   Source: SciCrunch Registry

http://cupsat.tu-bs.de/

A tool to predict changes in protein stability upon point mutations.

Proper citation: CUPSAT (RRID:SCR_010773) Copy   

•   Source: SciCrunch Registry

http://ls-snp.icm.jhu.edu/ls-snp-pdb/

A web tool for genome-wide annotation of human SNPs.

Proper citation: LS-SNP/PDB (RRID:SCR_010774) Copy   

•   Source: SciCrunch Registry