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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
REDIportal
 
Resource Report
Resource Website
10+ mentions
REDIportal (RRID:SCR_018490) data or information resource, portal, database, service resource, topical portal, atlas Comprehensive database of A-to-I RNA Editing Events. Atlas of A-to-I RNA editing events in human and other organisms. Collection of A-to-I events in body sites of healthy individuals from GTEx project. RNA Editing sites can be searched by genomic region, gene name and other relevant features as tissue of origin. Query results are shown in sortable and downloadable tables in which main characteristics of individual RNA editing events are reported. RNA-Seq and DNA-Seq coverage per site as well as RNA editing levels are provided. A-to-I RNA Editing Events, RNA editing events collection, atlas, database, GTEx project, genomic region, gene name, RNAseq, DNAseq, , bio.tools is listed by: Debian
is listed by: bio.tools
is related to: CLAIRE
is related to: SIGNOR
Italian Ministero dell Istruzione ;
Consiglio Nazionale delle Ricerche
PMID:27587585 Free, Freely available biotools:rediportal https://bio.tools/rediportal SCR_018490 2026-08-01 12:07:57 30
MB-GAN
 
Resource Report
Resource Website
1+ mentions
MB-GAN (RRID:SCR_019289) software resource, software application, simulation software Software tool as deep learning simulation framework for simulating realistic microbiome data. Can automatically learn from given microbial abundances and compute simulated abundances that are indistinguishable from it. Metagenomics, deep learning, generative adversarial network, microbiome data simulation, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Texas at Dallas; Texas; USA
DOI:10.1101/863977 Free, Available for download, Freely available biotools:mb-gan https://bio.tools/mb-gan SCR_019289 Microbiome Simulation via Generative Adversarial Network 2026-08-01 12:07:48 1
SVA
 
Resource Report
Resource Website
10+ mentions
SVA (RRID:SCR_002155) SVA commercial organization, software application, software resource Software package to annotate, visualize, and analyze the genetic variants identified through next-generation sequencing studies, including whole-genome sequencing (WGS) and exome sequencing studies. SVA aims to provide the research community with a user-friendly and efficient tool to analyze large amount of genetic variants, and to facilitate the identification of the genetic causes of human diseases and related traits. gene, genetic, genomic, annotate, visualize, genetic variant, next-generation sequencing, whole-genome sequencing, exome, sequencing, genome, disease, trait, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Duke University School of Medicine; North Carolina; USA
PMID:21624899 THIS RESOURCE IS NO LONGER IN SERVICE nlx_154666, OMICS_00190, biotools:sequencevariantanalyzer http://www.svaproject.org/, https://bio.tools/sequencevariantanalyzer SCR_002155 Sequence Variant Analyzer, SVA: Sequence Variant Analyzer 2026-08-01 12:10:44 16
Vascular Modeling Toolkit
 
Resource Report
Resource Website
50+ mentions
Vascular Modeling Toolkit (RRID:SCR_001893) vmtk software resource, software application, software toolkit Software collection of libraries and tools for 3D reconstruction, geometric analysis, mesh generation and surface data analysis for image-based modeling of blood vessels. 3d reconstruction, geometric analysis, mesh generation, surface data analysis, image-based modeling, blood vessel, reconstruction, 3d is listed by: Debian
is listed by: OMICtools
is related to: VMTK in 3D Slicer
PMID:19002516
PMID:19447701
DOI:10.1109/TMI.2009.2021652
Free, Available for download, Freely available nlx_155869, OMICS_13947 https://sources.debian.org/src/vmtk/ SCR_001893 vmtk - the Vascular Modeling Toolkit 2026-08-01 12:10:37 85
DINDEL
 
Resource Report
Resource Website
10+ mentions
DINDEL (RRID:SCR_001827) Dindel software resource, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 7,2024. Software program for calling small indels from short-read sequence data ("next generation sequence data"). It is currently designed to handle only Illumina data. Dindel takes BAM files with mapped Illumina read data and enables researchers to detect small indels and produce a VCF file of all the variant calls. It has been written in C++ and can be used on Linux-based and Mac computers (it has not been tested on Windows operating systems). indel, short-read, next generation sequence, illumina, gene, genetic, genomic, c++, linux, macos, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:20980555
DOI:10.1101/gr.112326.110
THIS RESOURCE IS NO LONGER IN SERVICE , nlx_154283, OMICS_00096, biotools:dindel https://bio.tools/dindel, https://sources.debian.org/src/dindel/ http://www.sanger.ac.uk/resources/software/dindel/ SCR_001827 Dindel: Accurate indel calls from short-read data 2026-08-01 12:10:44 44
metabnorm
 
Resource Report
Resource Website
metabnorm (RRID:SCR_001266) software resource, software application, standalone software Software tool as mixed model normalization method for metabolomics data.Uses normalization approach based on mixed model, with simultaneous estimation of correlation matrix. Metabolomics datasets, corelation, normalization, identifying metabolites, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
Cancer Research UK Cambridge Institute ;
Erik and Edith Fernström foundation ;
Cancer Research UK
PMID:24711654 Free, Available for download, Freely available OMICS_03548, biotools:metabnorm https://bio.tools/metabnorm SCR_001266 2026-08-01 12:10:43 0
PEDIGRAPH
 
Resource Report
Resource Website
10+ mentions
PEDIGRAPH (RRID:SCR_001938) Pedigraph software resource, software application A pedigree visualization program specifically designed to draw large, complex pedigrees. (entry from Genetic Analysis Software) Options include: * Full pedigree * Summarization * Extraction of individual pedigrees * Inbreeding calculation * Coancestry coefficient calculation * Color control * Drawing size * Page size and margins * Drawing styles gene, genetic, genomic, c, c++, ms-windows, linux, pedigree, java, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Minnesota Twin Cities; Minnesota; USA
PMID:14986440 Acknowledgement required, Copyrighted biotools:pedigraph, OMICS_00212, nlx_154519 https://bio.tools/pedigraph SCR_001938 2026-08-01 12:10:38 17
Apollo
 
Resource Report
Resource Website
100+ mentions
Apollo (RRID:SCR_001936) Apollo software resource, software application A standalone Java application with a GUI (graphical user interface) for editing genome annotations. Like GBrowse, it allows users to scroll and zoom in on areas of interest in a sequence; authorized users can edit annotations and write the changes back to the underlying database. Apollo can run off GFF3 or a Chado database, and it can also integrate with remote services, such as BLAST and Primer BLAST analyses. java, genome annotation, genome, annotation, windows, mac os x, linux, solaris, unix, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Generic Model Organism Database Project
PMID:19439563
PMID:12537571
DOI:10.1186/gb-2002-3-12-research0082
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_11761, biotools:apollo, OMICS_01933 https://bio.tools/apollo, https://sources.debian.org/src/aragorn/ SCR_001936 2026-08-01 12:10:44 274
FANTOM DB
 
Resource Report
Resource Website
10+ mentions
FANTOM DB (RRID:SCR_002678) FANTOM DB biomaterial supply resource, material resource The FANTOM consortium is an international collaborative research project initiated and organized by the RIKEN Omics Science Center. In earlier FANTOM efforts we cloned and annotated 103,000 full-length cDNAs from mouse and distributed them to researchers throughout the world. FANTOM1-3 focused on identifying the transcribed components of mammalian cells. This work improved estimates of the total number of genes and their alternative transcript isoforms in both human and mouse, expanded gene families, and revealed that a large fraction of the transcriptome is non-coding. In addition, with the development of Cap Analysis of Gene Expression (CAGE) FANTOM3 could map a large fraction of transcription start sites and revise our models of promoter structure. This updated web resource provides the previous FANTOM results mapped to current genome builds and presents the results of FANTOM4. In FANTOM4 the focus has changed to understanding how these components work together in the context of a biological network. Using deepCAGE (deep sequencing with CAGE) we monitored the dynamics of transcription start site (TSS) usage during a time course of monocytic differentiation in the acute myeloid leukemia cell line THP-1. This allowed us to identify active promoters, monitor their relative expression and define relevant regions for carrying out transcription factor binding site predictions. Computational methods were then used to build a network model of gene expression in this leukemia and the transcription factors key to its regulation. This work gives the first picture of the wiring between genes involved in acute myeloid leukemia and provides a strategy for identifying key factors that determine cell fates. In addition to the network, FANTOM4 data was used in two additional analyses. The first identified a novel class of short RNAs associated with transcription start sites and the second focused on the role of repetitive element expression in the transcriptome. TOOLS *Genome Browser: graphical display of genomic features, such as promoters, exon structures, H3K9 acetylation, transcription factors positioning on the genome, coupled with gene and promoter activities. *EdgeExpressDB: regulatory interactions, such as transcriptional regulation, post-transcriptional silencing with miRNA, and PPI, coupled with gene and promoter activities. *SwissRegulon: FANTOM4 TF regulation is predicted using Motif Activity Response Analysis (MARA) developed by Erik van Nimwegen at Biozentrum. Follow the link to carry out MARA on your own dataset. *Custom Tracks on the UCSC Genome Browser: FANTOM4 tracks on the UCSC Genome Browser Database. *The RIKEN integrated database of mammals: Integration of FANTOM4 data with other mammalian resources, in particular, produced by RIKEN. cdna clone, mouse, mouse cdna, human, bio.tools is listed by: One Mind Biospecimen Bank Listing
is listed by: bio.tools
is listed by: Debian
is related to: CAGE
has parent organization: RIKEN Omics Science Center
PMID:20211142 Free, Available for download, Freely available nif-0000-02833, biotools:fantom http://fantom3.gsc.riken.jp/, https://bio.tools/fantom SCR_002678 FANTOM: Functional Annotation of Mouse, FANTOM2, FANTOM1, Functional Annotation of the Mammalian Genome, FANTOM4, FANTOM3, FANTOM, Functional Annotation of Mouse 2026-08-01 12:10:33 20
e-Driver
 
Resource Report
Resource Website
1+ mentions
e-Driver (RRID:SCR_002674) software resource, software application, standalone software Software tool to identify cancer driver genes based on linear annotations of biological regions such as protein domains.Uses information on three-dimensional structures of mutated proteins to identify specific structural features. Then algorithm analyzes whether these features are enriched in cancer somatic mutations and are candidate driver genes. Identify cancer driver genes, candidate driver genes, perl, protein, mutated proteins, cancer somatic mutations, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Cancer PMID:25064568 Free, Available for download, Freely available biotools:e-Driver, OMICS_05288 https://bio.tools/e-Driver SCR_002674 2026-08-01 12:10:45 5
MRFSEQ
 
Resource Report
Resource Website
MRFSEQ (RRID:SCR_002972) software resource, algorithm resource Algorithm based on a Markov random field (MRF) model that uses additional gene coexpression data to enhance differential gene expression prediction power. It is able to call differentially expressed (DE) genes but also assign confidence scores to each inferred DE gene. markov, algorithm, gene expression, prediction algorithm, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at Riverside; California; USA
PMID:23793751 Free, Available for download, Freely available biotools:mrfseq, OMICS_01309 https://bio.tools/mrfseq SCR_002972 2026-08-01 12:10:42 0
IgBLAST
 
Resource Report
Resource Website
500+ mentions
IgBLAST (RRID:SCR_002873) software resource, software application THIS RESOURCE IS NO LONGER IN SERVICE.Documented on January 4,2023. IgBLAST was developed at NCBI to facilitate analysis of immunoglobulin V region sequences in GenBank. In addition to performing a regular BLAST search, IgBLAST has several additional functions: - Reports the germline V, D and J gene matches to the query sequence. - Annotates the immunoglobulin domains (FWR1 through FWR3). - Matches the returned hits (for databases other than germline genes) to the closest germline V genes, making it easier to identify related sequences. - Reveals the V(D)J junction details such as nucleotide homology between the ends of V(D)J segments and N nucleotide insertions. D and J gene reporting is only for nucleotide sequence search and requires a stretch of five or more nucleotide identity between the query and D or J genes. Sponsors: This resource is supported by the National Center for Biotechnology Information, a division of the U.S. National Library of Medicine. gene, analysis, domain, homology, immunoglobulin v, nucleotide, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: NCBI
PMID:23671333 Free, Freely available nif-0000-25554, biotools:igblast, OMICS_06083 https://bio.tools/igblast, https://sources.debian.org/src/ncbi-igblast/ SCR_002873 IgBLAST 2026-08-01 12:10:34 609
GoSurfer
 
Resource Report
Resource Website
1+ mentions
GoSurfer (RRID:SCR_005789) GoSurfer software resource, software application GoSurfer uses Gene Ontology (GO) information to analyze gene sets obtained from genome-wide computations or microarray analyses. GoSurfer is a graphical interactive data mining tool. It associates user input genes with GO terms and visualizes such GO terms as a hierarchical tree. Users can manipulate the tree output by various means, like setting heuristic thresholds or using statistical tests. Significantly important GO terms resulted from a statistical test can be highlighted. All related information are exportable either as texts or as graphics. Platform: Windows compatible gene, gene ontology, genome-wide, microarray, graph, data mining, statistical analysis, bioinformatics, genomics, gene cluster, multiple hypothesis testing, false discovery rate, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
has parent organization: Harvard T.H. Chan School of Public Health
PMID:15702958 Free for academic use biotools:gosurfer, nlx_149268 http://www.gosurfer.org, https://bio.tools/gosurfer http://bioinformatics.bioen.illinois.edu/gosurfer/index.htm SCR_005789 2026-08-01 12:10:51 2
BOMP: beta-barrel Outer Membrane protein Predictor
 
Resource Report
Resource Website
1+ mentions
BOMP: beta-barrel Outer Membrane protein Predictor (RRID:SCR_007268) software resource, software application BOMP is a tool for prediction of beta-barrel integral outer membrane proteins. The user may submit a list of proteins, and receive a list of predicted BOMPs. The program, called the beta-barrel Outer Membrane protein Predictor (BOMP), is based on two separate components to recognize integral beta-barrel proteins. The first component is a C-terminal pattern typical of many integral beta-barrel proteins. The second component calculates an integral beta-barrel score of the sequence based on the extent to which the sequence contains stretches of amino acids typical of transmembrane -strands. To use the BOMP tool simply paste your fasta-formatted sequences into the text area, or choose a file which contains sequences. Then hit the submit button. It is possible to perform a BLAST search parallel with the predictions, which may be suitable in some cases. Using the BLAST search will however increase the running time substantially. Sponsors: This work was supported in part by grants from the Norwegian Research Council [SUP 140785/420 (GABI); FUGE/CBU151899/ISO], and the Meltzer Foundation, University of Bergen. Keywords: Beta-barrel, Membrane, Protein, Program, Software, Beta strand, Bacteria, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Bergen; Bergen; Norway
biotools:bomp, nif-0000-30236 https://bio.tools/bomp SCR_007268 BOMP Program 2026-08-01 12:10:40 5
PsychoPy
 
Resource Report
Resource Website
1000+ mentions
PsychoPy (RRID:SCR_006571) PsychoPy software resource, software application Open source application to allow the presentation of stimuli and collection of data for a wide range of neuroscience, psychology and psychophysics experiments. It is intended as a free, powerful alternative to Presentation or e-Prime. console (text based), experimental control, freebsd, linux, macos, microsoft, magnetic resonance, posix/unix-like, python, win32 (ms windows), windows, neuroscience, psychology, psychophysics is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: University of Nottingham; Nottingham; United Kingdom
PMID:17254636
PMID:19198666
GNU General Public License nlx_155928 http://www.nitrc.org/projects/psychopy, https://sources.debian.org/src/psychopy/ SCR_006571 PsychoPy - Psychology software in Python 2026-08-01 12:10:50 1975
VarScan
 
Resource Report
Resource Website
1000+ mentions
VarScan (RRID:SCR_006849) VarScan, VarScan 2 software resource, software application Platform-independent, technology-independent software tool for identifying SNPs and indels in massively parallel sequencing of individual and pooled samples. Given data for a single sample, VarScan identifies and filters germline variants based on read counts, base quality, and allele frequency. Given data for a tumor-normal pair, VarScan also determines the somatic status of each variant (Germline, Somatic, or LOH) by comparing read counts between samples. (entry from Genetic Analysis Software). gene, genetic, genomic, java, illumina, solid, life/pgm, roche/454, next-generation sequencing, variant, mutation caller, exome, whole-genome, snp, copy number alteration, somatic mutation, subclonal mutation, mutation, bio.tools is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
is organization facet of: Washington University in St. Louis; Missouri; USA
PMID:22300766
PMID:19542151
DOI:10.1101/gr.129684.111
Free, Available for download, Freely available , nlx_154687, biotools:varscan, OMICS_00094 http://varscan.sourceforge.net/, http://dkoboldt.github.io/varscan/, https://bio.tools/varscan, https://sources.debian.org/src/varscan/ http://genome.wustl.edu/software/varscan, http://tvap.genome.wustl.edu/tools/varscan/ SCR_006849 Varscan2, VarScan - variant detection in massively parallel sequencing data, Varscan 2026-08-01 12:10:52 1769
zfishbook
 
Resource Report
Resource Website
1+ mentions
zfishbook (RRID:SCR_006896) zfishbook biomaterial supply resource, material resource Collection of revertible protein trap gene-breaking transposon (GBT) insertional mutants in zebrafish with active or cryopreserved lines from initially identified lines. Open to community-wide contributions including expression and functional annotation and represents world-wide central hub for information on how to obtain these lines from diverse members of International Zebrafish Protein Trap Consortium (IZPTC) and integration within other zebrafish community databases including Zebrafish Information Network (ZFIN), Ensembl and National Center for Biotechnology Information. Registration allows users to save their favorite lines for easy access, request lines from Mayo Clinic catalog, contribute to line annotation with appropriate credit, and puts them on optional mailing list for future zfishbook newletters and updates. gene-breaking transposon, expression-tagged, revertible mutation, gene, transposon, mutation, mutant, brain, muscle, skin, secretory, cardiac, brain line, muscle line, skin line, secretory line, cardiac line, plasmid, expression, functional annotation, gene-breaking transposon line, gene-break transposon mutagenesis, cell line, annotation, embryonic zebrafish, larval zebrafish, bio.tools is listed by: One Mind Biospecimen Bank Listing
is listed by: Debian
is listed by: bio.tools
is related to: Addgene
is related to: Zebrafish International Resource Center
has parent organization: Mayo Clinic Minnesota; Minnesota; USA
Mayo Clinic Cancer Center ;
Mayo Foundation ;
NIGMS GM63904;
NIDA DA14546;
NHGRI HG006431
PMID:22067444 Free, Freely available biotools:zfishbook, nlx_151613 https://bio.tools/zfishbook SCR_006896 book, z fish book, zfishbook, fish, z 2026-08-01 12:10:39 4
HTQC
 
Resource Report
Resource Website
10+ mentions
HTQC (RRID:SCR_006448) HTQC software resource, software toolkit A software toolkit including statistics tool for illumina high-throughput sequencing data, and filtration tools for sequence quality, length, tail quality, etc.. c++, illumina, command-line is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
PMID:23363224
DOI:10.1186/1471-2105-14-33
GNU General Public License, v3 OMICS_01052 https://sources.debian.org/src/htqc/ SCR_006448 HTQC - Quality control and filtration for illumina sequencing data 2026-08-01 12:10:50 42
LDSELECT
 
Resource Report
Resource Website
10+ mentions
LDSELECT (RRID:SCR_007010) LDSELECT software resource, software application Software program that analyzes patterns of linkage disequilibrium (LD) between polymorphic sites in a locus, and bins the SNPs on the basis of a threshold level of LD as measured by r2. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, genetic, genomic, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:ld_select, nlx_154426 https://bio.tools/ld_select SCR_007010 2026-08-01 12:10:52 15
PhyML
 
Resource Report
Resource Website
5000+ mentions
PhyML (RRID:SCR_014629) software resource, web application, source code Web phylogeny server based on the maximum-likelihood principle. phylogenic software, phylogeny, maximum likelihood, web server, bio.tools is used by: ProtTest
is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
works with: PAML
DOI:10.1093/molbev/msq060 Public server, Source code is available on request biotools:phyml, OMICS_04241 https://bio.tools/phyml, https://sources.debian.org/src/phyml/ SCR_014629 2026-08-01 12:11:04 7740

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