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https://sites.ifi.unicamp.br/gate/gate-ats/vidraria/

IFGW glass workshop, equipped with specialized staff, provides expertise in glass forming, welding, and cutting of Quartz and Borosilicate, as well as in design and technical drawing.

Proper citation: State University of Campinas Gleb Wataghin Physics Institute Vidraria/IFGW Core Facility (RRID:SCR_027639) Copy   

•   Source: SciCrunch Registry

https://www.bidmc.org/research/core-facilities/x-ray-crystallography-core

Core offers comprehensive protein expression, purification, characterization, and structural biology services, including advanced methods such as Cryo-Electron Microscopy (Cryo-EM) and X-ray Crystallography.

Proper citation: Beth Israel Deaconess Medical Center X-ray Crystallography Core Facility (RRID:SCR_027651) Copy   

•   Source: SciCrunch Registry

https://access-ci.org/

Provides advanced computing systems and services including supercomputer applications, AI and machine learning, big data analysis and storage. Offers suite of cyberinfrastructure coordination services targeted at supporting all areas of science and engineering research and education.

Proper citation: Advanced Cyberinfrastructure Coordination Ecosystem Services and Support Core Facility (RRID:SCR_027656) Copy   

•   Source: SciCrunch Registry

https://www.boisestate.edu/brc-cobre/matrix-biology/cores/biomedical-research-vivarium-core/

Core provides and supports gold standard of high quality mouse, rat and zebrafish care and services. All procedures are conducted according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals. The BRV is accredited at the highest standard of care through the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) International.

Proper citation: Boise State University Biomedical Research Vivarium Core Facility (RRID:SCR_027621) Copy   

•   Source: SciCrunch Registry

https://www.ladydavis.ca/en/about/core-facilities/cell-imaging/

Core provides expertise in confocal, live cell, and fluorescent microscopy. Provides services in experimental design, instrumentation, training, technical assistance, and scientific guidance from sample preparation to data analysis and publication.

Proper citation: Lady Davis Institute Cell Imaging Core Facility (RRID:SCR_027624) Copy   

•   Source: SciCrunch Registry

https://pace.gatech.edu/

Core provides high performance computing (HPC) resources with technical support services, infrastructure, software, and more. PACE maintains several computing clusters for Georgia Tech’s faculty, students, and staff.

Proper citation: Georgia Institute of Technology Partnership for an Advanced Computing Environment Core Facility (RRID:SCR_027619) Copy   

•   Source: SciCrunch Registry

https://www.washington.edu/research/shared-research-facilities-resources/northwest-metabolomics-research-center-nw-mrc/

Core provides targeted and untargeted measurements of small molecule metabolites utilizing LC-MS, high-field NMR and GC-MS analytical platforms. We also perform quantitative lipidomics and oxylipns metabolic flux analysis, statistical and pathway analysis, and biological interpretation.

Proper citation: University of Washington Northwest Metabolomics Research Center Core Facility (RRID:SCR_027599) Copy   

•   Source: SciCrunch Registry

https://rad.uw.edu/research/tbic

Core has resources available at Fred Hutch and UW in collaboration with multi-disciplinary imaging research groups specializing in respective imaging technologies. Provides services including: support for animal imaging; consultation for appropriate use of imaging; training and education; help with protocol development; infrastructural support; and strategic acquisition of new imaging equipment. Provides animal imaging equipment, including MRI, PET, US and optical to support scientific projects within the UW-FH Cancer Consortium.

Proper citation: University of Washington Translational BioImaging Core Facility (RRID:SCR_027591) Copy   

•   Source: SciCrunch Registry

https://github.com/RWParsons/circacompare

Software R package for statistical analyses and comparison of two circadian rhythms. Used to estimate and statistically support differences in mesor, amplitude and phase, between circadian rhythms.

Proper citation: CircaCompare (RRID:SCR_027626) Copy   

•   Source: SciCrunch Registry

https://www.montana.edu/mbi/multiphoton_laboratory.html

Core provides multiphoton characterization of Genetically-Encoded Probes for the BRAIN Initiative researchers and broader neuroscience community. Services include Measuring of 2-photon absorption spectra in absolute, cross section values; Measuring 3-photon absorption spectra and cross sections; Characterizing multiphoton photobleaching parameters, i.e. quantum yields, nonlinear absorption cross sections:Measuring one-photon absorption, emission, and excitation spectra;Measuring fluorescence quantum yields and lifetimes;Evolving brighter two-photon probes.

Proper citation: Montana State University Biophotonics Core Facility (RRID:SCR_027627) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/core-facilities/electron-microscopy

EM Core Facility offers instrumentation and training for range of Electron Microscopy applications. Instrumentation includes Thermofisher Tundra cryo-TEM, Tecnai T12 TEM, Magellan 400 SEM, JEOL JEM-2200FS, Vitrobot Mark IV, (cryo)microtomes, and other auxiliary equipment.

Proper citation: University of Massachusetts Amherst Electron Microscopy Core Facility (RRID:SCR_027853) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/biostatistics/

Core provides biostatistical review of grant applications, offering clear, practical feedback on feasibility and statistical rigor to investigators and review panels. We support investigators across the research lifecycle, from grant proposal development and clinical protocol design to laboratory, animal, and epidemiologic study planning. Services also include short-term consultations, study monitoring, data analysis, manuscript preparation, and responses to peer review.

Proper citation: Augusta University GCC Biostatistics Core Facility (RRID:SCR_027784) Copy   

•   Source: SciCrunch Registry

https://fralinlifesci.vt.edu/core-services/flow-cytometry.html

Facility offers traditional data acquisition, analysis, and cell sorting as well as imaging cytometry. Provided equipment includes: BD FACSAria Fusion: A cell sorter that can also be used as an analyzer, it is equipped with 488nm, 640nm, and 405nm excitation sources and is equipped to analyze up to fifteen parameters simultaneously. The Fusion is capable of processing up to 70,000 events per second and sorting up to four different cell populations at once. It is also equipped with an Automatic Cell Deposition Unit (ACDU) that allows sorting of cells into plates or onto slides; Amnis ImageStream MarkII: this imaging cytometer combines the speed and objectivity of flow cytometry with the detailed imagery of microscopy to allow you to objectively and quantitatively describe biological processes based on cell size, shape, and fluorescence location, texture, and signal intensity.This open platform enables new methods of research and improves traditional flow and imaging based applications. It is equipped with 405nm, 488nm, and 642nm excitation sources and is able to analyze up to twelve parameters simultaneously. It has 20X, 40X, and 60X objective lenses and Enhanced Depth of Field technology. It can process several thousand cells per second.

Proper citation: Virginia Tech Flow Cytometry Core Facility (RRID:SCR_027816) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/antitumor-assessment

Core provides support for early discovery and in vivo testing of antitumor detection and therapeutic agents. Provides resources, professional and technical expertise, and advisory services related to evaluation of agents with potential diagnostic or therapeutic activity. ATA Core works closely with investigators to establish preclinical models, including Patient-Derived Xenograft (PDX) and Patient-Derived Organoid (PDO) models, for the design and execution of pharmacokinetic (PK), toxicity, and in vivo efficacy studies. Assists investigators in determining the best formulation, administration route, and treatment schedule for each new compound, either alone or in combination with other agents.

Proper citation: Memorial Sloan Kettering Cancer Center Antitumor Assessment Core Facility (RRID:SCR_027795) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/genome-editing-screening

Core Facility provides functional genomics, highthroughput screening (HTS), and high-content screening (HCS) services toward the discovery of novel cancer targets and elucidation of complex, aberrant cellular pathways. Offers assistance and training in range of cloning, customized library design, lentivirus production, assay development, screening, and image analysis considerations to assist researchers in harnessing these powerful target identification tools and drug screening methodologies. Offers CRISPR-mediated transcriptional activation/interference (CRISPRa/CRISPRi) technologies combined with lentivirus delivery systems, customized stable isogenic cell line generation (knockout, HDR-directed knock-in, knockdown, base editing, and prime editing) toward the generation of unique cancer cell line models.

Proper citation: Memorial Sloan Kettering Cancer Center Genome Editing and Screening Core Facility (RRID:SCR_027799) Copy   

•   Source: SciCrunch Registry

https://www.medschool.umaryland.edu/cibr/core/em/

Core is part of the Center for Innovative Biomedical Resources (CIBR) and is located on the 6th floor of Howard Hall. All services, instrumentation, and training courses are available to anyone, academic or private users, with an interest in electron microscopy.EMCIF services are managed by iLab core facility management program. New users must register in iLab to access instrument and EMCIF services.

Proper citation: University of Maryland School of Medicine Baltimore Electron Microscopy Core Imaging Facility (RRID:SCR_027760) Copy   

•   Source: SciCrunch Registry

https://www.danforthcenter.org/our-work/core-facilities/#field-research-site

Field Research Site is a core facility providing scientists with advanced field research infrastructure and crop management capabilities. Offers diverse agricultural practices including full tillage, no-till systems, irrigation, precision spraying, and plot planting for row crops and specialty crops. On-site resources include multiple drying rooms, walk-in freezers, and dedicated processing spaces for soil, tissue, and seed samples.

Proper citation: Donald Danforth Plant Science Center Field Research Site Core Facility (RRID:SCR_027897) Copy   

•   Source: SciCrunch Registry

https://www.immunology.pitt.edu/core-facilities/mouse-embryo-services-mes-core

Core provides services including generation of gene editing mice, transgenic mice, ES cell microinjection into blastocysts to create germline competent chimera, cryopreservation and long-term storage of mouse sperm/embryos, recovery of mouse lines from cryopreserved germplasm, in vitro fertilization for mouse line rescue and re-derivation of pathogen free mouse strains.

Proper citation: University of Pittsburgh Mouse Embryo Services Core Facility (RRID:SCR_027775) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/proteomics-metabolomics-core

Core provides mass spectrometric sequencing and quantitation of peptides and proteins to support basic, translational, and clinical research programs at MSK. Utilizes modern high-resolution mass spectrometry and nanoscale liquid chromatography in conjuction with biochemical processing of samples with the end goal of determining the identity, relative abundance, and presence of post translational modifications from purified components, cell lysates, tissues, and select fluid such as cerebral spinal fluid. Advice is provided by the Core staff to facilitate the design, execution, and analysis of experiments.

Proper citation: Memorial Sloan Kettering Cancer Center Proteomics and Metabolomics Core Facility (RRID:SCR_027811) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/animal-imaging

Core offers suite of animal imaging modalities, including MRI, PET, CT, SPECT, and ultrasound, all commonly used in clinical settings, enhancing the likelihood that findings in animal models will be translatable to human patients. Key instruments include 7.0T and 9.4T MRI systems, PET/MR, PET/CT, SPECT/CT, and advanced ultrasound systems, alongside specialized equipment including a small animal radiation therapy unit and variety of ancillary tools for advanced imaging analysis.

Proper citation: Memorial Sloan Kettering Cancer Center Animal Imaging Core Facility (RRID:SCR_027810) Copy   

•   Source: SciCrunch Registry