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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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Human Tissue and Organ for Research Resource (HTORR) Resource Report Resource Website |
Human Tissue and Organ for Research Resource (HTORR) (RRID:SCR_002859) | HTORR | biomaterial supply resource, tissue bank, material resource | NDRI’s Human Tissue and Organs for Research Resource (HTORR) Program has been funded by the National Institutes of Health (NIH) for over 30 consecutive years to support research programs across multiple disciplines. It is through the HTORR program that NDRI provides academic biomedical investigators with donated normal and diseased human tissues and organs recovered from a diverse donor pool using customized procurement, processing, and preservation and distribution protocols. Our HTORR Program supports academic biomedical research investigators needs by providing: Access to a wide array of human biospecimens from any body system * Customized procurement in a variety of preservation formats including fresh, frozen, and fixed suitable for various analytical techniques * Reduced costs for tissue procurement * Technical support to design your studies utilizing human biospecimens * Letters of support and budgetary information for grant applications | tissue, organ, nervous system, pulmonary system, cardiovascular system, endocrine system, eye, bone, cartilage, normal, diseased, human immunodeficiency virus, heart, kidney, lung, brain, liver, eye, bone, joint, disease, rare disease, endocrinology, eye bank, immunology, infectious disease, nephrology, nervous system, ophthalmology, pathology, pulmonary system, research, specimen, toxicology, transplantation, catalog |
is listed by: One Mind Biospecimen Bank Listing is listed by: Collaborating for the Advancement of Interdisciplinary Research in Benign Urology has parent organization: National Disease Research Interchange has parent organization: National Center for Research Resources |
Normal, Disease, Human immunodeficiency virus, Rare disease | NIH Office of the Director U42 OD011158 | Free, Freely available | nif-0000-25417 | https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources | http://www.ncrr.nih.gov/clinical%5Fresearch%5Fresources/resource%5Fdirectory/human_tissue_and_organ_resource_for_research/ | SCR_002859 | Human Tissue Organ Resource for Research, Human Tissues and Organs for Research, Human Tissues and Organs for Research (HTOR), Human Tissues Organs for Research | 2026-08-11 09:40:38 | 0 | |||
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Boston University Biospecimen Archive Research Core Resource Report Resource Website 1+ mentions |
Boston University Biospecimen Archive Research Core (RRID:SCR_005363) | BU BARC | biomaterial supply resource, tissue bank, material resource | Biospecimen repository of normal and diseased human material from a variety of tissues and conditions along with clinical annotation. Both frozen aliquots and paraffin embedded tissue are available. Biospecimens are available to qualified researchers with IRB approval. * Preliminary inquires please contact Cheryl Spencer at cheryl.spencer (at) bmc.org | disease, normal, cancer, tumor, colon, inflammatory bowel disease, rectal cancer, colon cancer, tonsil, obstructive sleep apnea, tonsillitis, parathyroid, parathyroid adenoma, stomach, stomach cancer, prostate, prostate cancer, uterus, uterine cancer, lung, squamous cell carcinoma, adenocarcinoma, ovary, ovarian cancer, thyroid, thyroid papillary carcinoma, kidney, papillary renal cell carcinoma, renal cell carcinoma, clear cell carcinoma, breast, ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, tissue, cancer tissue, colon tissue, tonsil tissue, parathyroid tissue, stomach tissue, prostate tissue, uterine tissue, lung tissue, ovarian tissue, thyroid tissue, kidney tissue, breast tissue, frozen, paraffin block, blood, biopsy, heart disease, diabetes, brain, brain tissue, adrenal, adrenal tissue, parotid, parotid tissue, thymus, pancreas, cervix, esophagus, thymus tissue, pancreatic tissue, cervical tissue, esophageal tissue |
is listed by: One Mind Biospecimen Bank Listing has parent organization: Boston University Medical Campus; Massachusetts; USA has parent organization: Boston University School of Medicine; Massachusetts; USA |
Disease, Cancer, Tumor, Normal, Heart disease, Diabetes, Inflammatory bowel disease, Rectal cancer, Colon cancer, Obstructive sleep apnea, Tonsillitis, Parathyroid adenoma, Stomach cancer, Prostate cancer, Uterine cancer, Squamous cell carcinoma, Adenocarcinoma, Ovarian cancer, Thyroid papillary carcinoma, Papillary renal cell carcinoma, Renal cell carcinoma, Clear cell carcinoma, Ductal carcinoma in situ, Invasive ductal carcinoma, Invasive lobular carcinoma | Public: The mission of the Biospecimen Archive Research Core (BARC) is to collect high quality samples of normal and diseased human material with appropriate clinical annotation and make these materials, Known as biospecimens, Available to qualified researchers while ensuring the informed consent, Safety and anonymity of all providers. | nlx_144430 | SCR_005363 | BU Biospecimen Archive Research Core, Boston University Biospecimen Archive Research Core (BARC), Biospecimen Archive Research Core Boston University Medical Center, Boston University Medical Center Biospecimen Archive Research Core, BUMC BARC, BUMC Biospecimen Archive Research Core | 2026-08-11 09:41:17 | 1 | ||||||
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Family Investigation of Nephropathy of Diabetes Resource Report Resource Website |
Family Investigation of Nephropathy of Diabetes (RRID:SCR_001525) | FIND, F.I.N.D. | clinical trial, resource | Multicenter observational study designed to identify genetic determinants of diabetic nephropathy. It is conducted in eleven U.S. clinical centers and a coordinating center, and with four ethnic groups (European Americans, African Americans, Mexican Americans, and American Indians). Two strategies are used to localize susceptibility genes: a family-based linkage study and a case-control study using mapping by admixture linkage disequilibrium (MALD). In the family-based study, probands with diabetic nephropathy are recruited with their parents and selected siblings. Linkage analyses will be conducted to identify chromosomal regions containing genes that influence the development of diabetic nephropathy or related quantitative traits such as serum creatinine concentration, urinary albumin excretion, and plasma glucose concentrations. Regions showing evidence of linkage will be examined further with both genetic linkage and association studies to identify genes that influence diabetic nephropathy or related traits. Two types of MALD studies are being done. One is a case-control study of unrelated individuals of Mexican American heritage in which both cases and controls have diabetes, but only the case has nephropathy. The other is a case-control study of African American patients with nephropathy (cases) and their spouses (controls) unaffected by diabetes and nephropathy; offspring are genotyped when available to provide haplotype data. The specific goals of this program: * Delineate genomic regions associated with the development and progression of renal disease(s) * Evaluate whether there is a genetic link between diabetic nephropathy and diabetic retinopathy * Improve outcomes * Provide protection for people at risk and slow the progression of renal disease * Help establish a resource for genetic studies of kidney disease and diabetic complications by creating a repository of genetic samples and a database * Encourage studies of the genetics of progressive renal disease | genetic susceptibility, genetic pathway, renal, kidney, outcome, gene, genetics, european-american, african-american, mexican-american, american-indian, linkage association study, admixture linkage disequilibrium, mapping by admixture linkage disequilibrium, serum creatinine, urinary protein excretion, plasma glucose level, blood pressure, blood lipid level, trait, linkage, adult human, male, female, clinical |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases |
NIDDK 5R01DK053591 | PMID:15642484 | Free, Freely available | nlx_152825 | https://www.niddkrepository.org/studies/find/ | SCR_001525 | Family Investigation of Nephropathy and Diabetes (F.I.N.D.), Family Investigation of Nephropathy & Diabetes | 2026-08-11 09:40:22 | 0 | ||||
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RiVuR Resource Report Resource Website 1+ mentions |
RiVuR (RRID:SCR_001539) | RIVUR | clinical trial, resource | Multicenter, randomized, double-blind, placebo-controlled trial is designed to determine whether daily antimicrobial prophylaxis is superior to placebo in preventing recurrence of urinary tract infection (UTI) in children with vesicoureteral reflux (VUR). The basic eligibility criteria are: (1) age at randomization of at least 2 months, but less than 6 years, (2) a diagnosed first febrile or symptomatic UTI within 42 days prior to randomization that was appropriately treated, and (3) presence of Grade I-IV VUR based on voiding cystourethrogram (VCUG). Patients will be randomly assigned to treatment for 2 years with daily antimicrobial prophylaxis (trimethoprim-sulfamethoxazole) or placebo. The study is designed to recruit 600 children (approximately 300 in each treatment group) over an 18-24 month period. The primary endpoint is recurrence of UTI. In addition, patients will be evaluated for secondary endpoints related to renal scarring and antimicrobial resistance. Scarring will be determined based on renal scintigraphy by 99mTc dimercaptosuccinic (DMSA) scan. Quality of life, compliance, safety parameters, utilization of health resources, and change in VUR will be assessed periodically throughout the study. | child, antimicrobial prophylaxis, placebo, antibiotic, renal scarring, pediatric, trimethoprim-sulfamethoxazole, intervention, kidney, antibiotic resistance, young human, infant, bibliography, clinical, trimethoprim, sulfamethoxazole |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA |
Vesico-ureteral reflux, Urinary tract infection | NIDDK | PMID:19570724 PMID:19018048 PMID:18076937 PMID:19018047 PMID:19086141 |
Free, Freely available | nlx_152848 | http://www.cscc.unc.edu/rivur/ | SCR_001539 | Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR), Randomized Intervention for Children with Vesicoureteral Reflux, Randomized Intervention for Vesicoureteral Reflux | 2026-08-11 09:40:22 | 1 | |||
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National Digestive Diseases Information Clearinghouse Resource Report Resource Website |
National Digestive Diseases Information Clearinghouse (RRID:SCR_006771) | NDDIC | service resource, data or information resource, resource, narrative resource, training material | Information dissemination service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) established to increase knowledge and understanding about digestive diseases among people with these conditions and their families, health care professionals, and the general public: online, in booklets and fact sheets, by email, and over the phone. To carry out this mission, NDDIC works closely with a coordinating panel of representatives from Federal agencies, voluntary organizations on the national level, and professional groups to identify and respond to informational needs about digestive diseases. NDDIC provides the following informational products and services: * Response to inquiries about digestive diseases - ranging from information about available patient and professional education materials to statistical data. By phone (8:30 a.m. to 5 p.m. eastern time, M-F), fax, mail, and email. * Publications about specific digestive diseases, provided free of copyright, in varying reading levels. Available online or as booklets and brochures. NDDIC also sends publications to health fairs and community events. * Referrals to health professionals through the National Library of Medicine''''s MEDLINEplus includes a consumer-friendly listing of organizations that will assist you in your search for physicians and other health professionals. * Exhibits at professional meetings specific to digestive diseases, as well as cross-cutting professional meetings. NDDIC exhibits at nine professional meetings each year, including Digestive Diseases Week, American College of Gastroenterology, Society of Gastroenterology Nurses and Associates, American Academy of Family Physicians, American Academy of Physician Assistants, American Nurses Association, and the National Conference for Nurse Practitioners. | digestive health, disease, statistics, publication, bowel control, complication, diabetes, digestive, kidney, urologic, topical portal |
is related to: NIDDK Information Network (dkNET) has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is parent organization of: Digestive Diseases Statistics for the United States |
Digestive disease, Celiac disease | NIDDK | Free, Public | nlx_152710 | SCR_006771 | National Digestive Diseases Information Clearinghouse (NDDIC) | 2026-08-11 09:41:24 | 0 | |||||
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ShARM Resource Report Resource Website 1+ mentions |
ShARM (RRID:SCR_003120) | ShARM | biomaterial supply resource, tissue bank, material resource | A not for profit organization to accelerate research into aging by sharing resources: providing access to cost and time effective, aged murine tissue through a biorepository and database of live ageing colonies, as well as promoting the networking of researchers and dissemination of knowledge through its online collaborative environment; MiCEPACE. ShARM will provide valuable resources for the scientific community while helping to reduce the number of animals used in vital research into aging. The biobank of tissue and networking facility will enable scientists to access shared research material and data. By making use of collective resources, the number of individual animals required in research experiments can be minimized. The project also has the added value of helping to reduce the costs of research by connecting scientists, pooling resource and combining knowledge. ShARM works in partnership with MRC Harwell and the Centre for Intergrated Research into Musculoskeletal Ageing (CIMA). | data sharing, female, male, gut, heart, kidney, livers, lung, mammary fat, muscle, pancreas, bat, bladder, bone, brain, femur, skin, spleen, thymus, tibia, wat, aged tissue, aged mouse, murine model | is listed by: One Mind Biospecimen Bank Listing | Aging, Control, Young control | Wellcome Trust | PMID:24085518 | Free, Freely available | nlx_156767 | SCR_003120 | Shard Ageing Research Models | 2026-08-11 09:40:40 | 4 | ||||
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Mayo Clinic O'Brien Urology Center Biostatistics and Epidemiology Core Resource Report Resource Website |
Mayo Clinic O'Brien Urology Center Biostatistics and Epidemiology Core (RRID:SCR_015452) | service resource, core facility, access service resource, resource | Core that is responsible for all statistical, data management and epidemiological aspects of studies in the Mayo Clinic O'Brien Urology Research Center. Its services include consultation to project investigators regarding study design, data analysis and interpretation of results, maintanence of the Olmsted County kidney stone database, and development of additional linkable databases and quality control procedures. | nephrolithiasis, statistical analysis, epidemiology, data management |
is listed by: NIDDK Information Network (dkNET) has parent organization: Mayo Clinic has parent organization: Mayo Clinic O'Brien Urology Center is organization facet of: Mayo Clinic O'Brien Urology Center |
NIDDK U54DK100227 | Available to the O'Brien Urology Research Center community | SCR_015452 | 2026-08-11 09:43:09 | 0 | |||||||||
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The Li Lab at UCSF Resource Report Resource Website 100+ mentions |
The Li Lab at UCSF (RRID:SCR_010269) | data or information resource, database | Laboratory portal that houses the following databases. MethPrimer is a program for designing bisulfite-conversion-based Methylation PCR Primers. Currently, it can design primers for two types of bisulfite PCR: 1) Methylation-Specific PCR (MSP) and 2) Bisulfite-Sequencing PCR (BSP) or Bisulfite-Restriction PCR. CpG Island Prediction MethPrimer can also analyze input sequences for the existence of CpG islands. Human Prostate Gene Database (PGDB) is a curated and integrated database of human genes related to the prostate and prostatic diseases. Human Kidney Gene Database (KGDB) is a curated and integrated database of human genes related to the kidney and renal diseases. The Li Lab is interested in understanding how small RNA regulates gene expression at the transcriptional level by targeting gene promoter sequences, particularly how small RNA activates gene transcription, a phenomenon termed RNA activation (RNAa). | has parent organization: University of California at San Francisco; California; USA | nlx_156928 | SCR_010269 | The Li Lab in the Department of Urology and Helen Diller Family Comprehensive Cancer Center, UCSF | 2026-08-10 09:33:57 | 195 | ||||||||||
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Coalition For Accelerating Standards and Therapies Resource Report Resource Website 1+ mentions |
Coalition For Accelerating Standards and Therapies (RRID:SCR_000206) | CFAST | data or information resource, portal | Consortium establishing data standards, tools and methods for conducting research in therapeutic areas important to public health including Alzheimer's disease, Parkinson's disease, multiple sclerosis, polycystic kidney disease, and tuberculosis.CDISC and C-Path have agreed to discontinue using separate CFAST brand, but they both remain committed to this mission and continue to partner to develop and publish therapeutic area data standards. | CDISC, C-Path, drug, clinical trial, data element, data sharing, clinical, virology |
is listed by: Consortia-pedia has parent organization: Critical Path Institute; Arizona; USA |
FDA 1U01FD003865-01 | nlx_157879 | SCR_000206 | Coalition For Accelerating Standards and Therapies (CFAST) | 2026-08-10 09:31:06 | 1 | |||||||
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Leica: LMD6 Laser Microdissection microscope Resource Report Resource Website |
Leica: LMD6 Laser Microdissection microscope (RRID:SCR_024658) | instrument resource | Laser Microdissection system enables users to isolate specific single cells or entire areas of tissue. Powered by unique laser design and dynamic software, Leica LMD systems allow users to easily isolate Regions of Interest from entire areas of tissue down to single cells or even subcellular structures such as chromosomes. Leica LMD6 is for standard tissue dissection. Used for standard applications dissecting soft tissues such as brain, liver, or kidney. | Laser Microdissection system, Leica, microscope, standard tissue dissection, dissecting soft tissues, brain dissection, liver dissection, kidney dissection, | https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/main/PDF/SCR_024658.pdf | Model_Number_LMD6 | https://manualzz.com/doc/17928252/leica_lmd6_7-technicalbrochure_en_2016.03.24 | SCR_024658 | Leica LMD6 | 2026-08-08 12:03:04 | 0 | ||||||||
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Glomerular Filtration Rate Calculators Resource Report Resource Website |
Glomerular Filtration Rate Calculators (RRID:SCR_006443) | GFR Calculators | service resource, analysis service resource, resource, data analysis service, production service resource | Glomerular Filtration Rate (GFR) calculators to estimate kidney function for adults (MDRD GFR Calculator) and children (Schwartz GFR Calculator). In adults, the recommended equation for estimating glomerular filtration rate (GFR) from serum creatinine is the Modification of Diet in Renal Disease (MDRD) Study equation. The IDMS-traceable version of the MDRD Study equation is used. Currently the best equation for estimating glomerular filtration rate (GFR) from serum creatinine in children is the Bedside Schwartz equation for use with creatinine methods with calibration traceable to IDMS. Using the original Schwartz equation with a creatinine value from a method with calibration traceable to IDMS will overestimate GFR. | adult human, child, glomerular filtration rate, estimate, kidney function, serum creatinine |
is related to: Creatinine Standardization Program is related to: NIDDK Information Network (dkNET) has parent organization: National Kidney Disease Education Program |
Chronic kidney disease | NIDDK | PMID:16908915 | nlx_152733 | SCR_006443 | Glomerular Filtration Rate Calculator, Glomerular Filtration Rate (GFR) Calculator | 2026-08-11 09:41:20 | 0 | |||||
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Michigan Center for Diabetes Translational Research Resource Report Resource Website 1+ mentions |
Michigan Center for Diabetes Translational Research (RRID:SCR_015187) | MCDTR | portal, topical portal, disease-related portal, data or information resource | Multidisciplinary unit of the University of Michigan funded by National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health. MCDTR is one of seven NIH Centers funded to focus on type 2 translational research in diabetes with mission to establish, promote, and enhance multidisciplinary collaboration among researchers directed at prevention and control of diabetes, its complications, and comorbidities, by providing access to specialized expertise and resources. | translational diabetes research, multidisciplinary collabroation, clinical research, implementation research |
is affiliated with: Centers for Diabetes Translation Research has parent organization: University of Michigan Medical School; Michigan; USA is parent organization of: Michigan Center for Diabetes Translational Research Administrative Core Facility is parent organization of: Michigan Center for Diabetes Translational Research Methods and Measurements Core is parent organization of: Michigan Center for Diabetes Translational Research Intervention and Technology Research Core is parent organization of: Michigan Center for Diabetes Translational Research Leveraging Community, Peer, and Family Support Core Facility has organization facet: Michigan Center for Diabetes Translational Research Administrative Core Facility has organization facet: Michigan Center for Diabetes Translational Research Methods and Measurements Core has organization facet: Michigan Center for Diabetes Translational Research Intervention and Technology Research Core has organization facet: Michigan Center for Diabetes Translational Research Leveraging Community, Peer, and Family Support Core Facility is organization facet of: Centers for Diabetes Translation Research |
Diabetes | NIDDK P30DK092926 | http://diabetesresearch.med.umich.edu | SCR_015187 | 2026-08-11 09:42:57 | 1 | |||||||
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Baxter Resource Report Resource Website 50+ mentions |
Baxter (RRID:SCR_003974) | BAX | commercial organization | A global healthcare company with expertise in medical devices, pharmaceuticals and biotechnology. Through its subsidiaries, they develop, manufacture and market products that save and sustain the lives of people with hemophilia, immune disorders, infectious diseases, kidney disease, trauma, and other chronic and acute medical conditions. BioScience Baxter is a manufacturer of recombinant and plasma-based proteins to treat hemophilia and other bleeding disorders; plasma-based therapies to treat immune deficiencies, alpha 1-antitrypsin deficiency, burns and shock, and other chronic and acute blood-related conditions; products for regenerative medicine, such as biosurgery products; and vaccines. Baxter''s Medical Products business manufactures products used in the delivery of fluids and drugs to patients. These include intravenous (IV) solutions and administration sets, premixed drugs and drug-reconstitution systems, IV nutrition products, infusion pumps and inhalation anesthetics. The business also provides products and services related to pharmacy compounding, drug formulation and packaging technologies. In addition, Baxter''s Medical Products business is a leader in Renal home-based therapies, such as peritoneal dialysis, and offers other products and services for people with end-stage kidney disease. | health care, medical equipment, bioscience, medical product, medical device, pharmaceutical, biotechnology | is related to: Kidney Health Initiative | Hemophilia, Kidney disease, Immune disorder, Chronic medical condition, Acute medical condition, Infectious disease, Trauma, Bleeding disorder | Wikidata: Q43895073, grid.487322.8, nlx_158381, ISNI: 0000 0000 9098 0655 | https://ror.org/01mgtdr23 | SCR_003974 | Baxter International Inc., Baxter International | 2026-08-08 11:58:08 | 51 | ||||||
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Folic Acid for Vascular Outcome Reduction in Transplantation Resource Report Resource Website 1+ mentions |
Folic Acid for Vascular Outcome Reduction in Transplantation (RRID:SCR_001505) | FAVORIT | clinical trial, resource | Multi-center, randomized, double blind controlled clinical trial to determine whether treatment with a standard multivitamin augmented with high doses of folic acid, vitamin B6 and vitamin B12 reduces the rate of cardiovascular disease outcomes in renal transplant recipients relative to participants receiving a similar multivitamin that contains no folic acid. This study hopes to show that by reducing the level of homocysteine in the body, the risk of heart disease is also reduced among kidney transplant patients. | multivitamin, folic acid, vitamin b6, vitamin b12, outcome, homocysteine, adult human, middle adult human, late adult human, vitamin, bibliography |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA |
Cardiovascular disease, Kidney transplant recipient | NIDDK U01DK061700 | PMID:16923411 | Free, Freely available | nlx_152827 | http://www.cscc.unc.edu/favorit/ | http://www.cscc.unc.edu/favorit/favdescrip.htm | SCR_001505 | Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT) | 2026-08-11 09:40:22 | 1 | ||
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Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center Biomarker Core Resource Report Resource Website |
Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center Biomarker Core (RRID:SCR_015300) | service resource, core facility, access service resource, resource | Core whose goals are to provide high throughput Clinical Biofluid Profiling Services (including initial web-based and in-person consultation, study design, sample preparation and processing, data acquisition, data analysis, protein purification, target identification, and specific assay development and validation) and services pertaining to Biomarker measurement and validation (including design of ELISA and Western Blots, measurement of known and emerging markers of acute and chronic kidney diseases, as well as consultation for biomarker statistics and clinical trials design). | biomarker, clinical trials |
is listed by: NIDDK Information Network (dkNET) has parent organization: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center is organization facet of: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center |
NIDDK P50 DK096418 | Available to the Pediatric Nephrology Center of Excellence community | SCR_015300 | 2026-08-11 09:43:00 | 0 | |||||||||
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Diabetes Control and Complications Trial Resource Report Resource Website |
Diabetes Control and Complications Trial (RRID:SCR_006805) | DCCT | data or information resource, clinical trial, resource, database | Clinical study that showed that keeping blood glucose levels as close to normal as possible slows the onset and progression of eye, kidney, and nerve diseases caused by diabetes. EDIC is a follow-up study of people who participated in DCCT. The DCCT involved 1,441 volunteers, ages 13 to 39, with type 1 diabetes and 29 medical centers in the United States and Canada. Volunteers had to have had diabetes for at least 1 year but no longer than 15 years. They also were required to have no, or only early signs of, diabetic eye disease. The study compared the effects of standard control of blood glucose versus intensive control on the complications of diabetes. Intensive control meant keeping hemoglobin A1C levels as close as possible to the normal value of 6 percent or less. The A1C blood test reflects a person''''s average blood glucose over the last 2 to 3 months. Volunteers were randomly assigned to each treatment group. DCCT Study Findings * Intensive blood glucose control reduces risk of ** eye disease: 76% reduced risk ** kidney disease: 50% reduced risk ** nerve disease: 60% reduced risk When the DCCT ended, researchers continued to study more than 90 percent of participants. The follow-up study, called Epidemiology of Diabetes Interventions and Complications (EDIC), is assessing the incidence and predictors of cardiovascular disease events such as heart attack, stroke, or needed heart surgery, as well as diabetic complications related to the eye, kidney, and nerves. The EDIC study is also examining the impact of intensive control versus standard control on quality of life. Another objective is to look at the cost-effectiveness of intensive control. EDIC Study Findings * Intensive blood glucose control reduces risk of ** any cardiovascular disease event: 42% reduced risk ** nonfatal heart attack, stroke, or death from cardiovascular causes: 57% reduced risk | blood glucose, adolescent, young human, middle adult human, longitudinal, eye disease, kidney disease, nerve disease, cardiovascular disease, heart attack, stroke, blood pressure, blood lipid, complication |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Central Repository is related to: Epidemiology of Diabetes Interventions and Complications is related to: Epidemiology of Diabetes Interventions and Complications is related to: NIDDK Information Network (dkNET) has parent organization: National Diabetes Information Clearinghouse |
Type 1 diabetes, Diabetes | NIDDK | nlx_152798 | SCR_006805 | DCCT and EDIC: The Diabetes Control and Complications Trial and Follow-up Study | 2026-08-11 09:41:27 | 0 | ||||||
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Collaborating for the Advancement of Interdisciplinary Research in Benign Urology Resource Report Resource Website 1+ mentions |
Collaborating for the Advancement of Interdisciplinary Research in Benign Urology (RRID:SCR_022876) | CAIRIBU | data or information resource, topical portal, portal, disease-related portal | Community of researchers studying benign urology diseases at U54 O’Brien Cooperative Research Centers, P20 Exploratory Centers, and K12 Career Development Programs funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), one of the institutes within the National Institutes of Health (NIH). CAIRIBU Centers and Programs are united around the overall objectives of improving our understanding of the mechanisms of urogenital diseases and developing clinical therapies for treating them by building collaborative and interactive research platforms that span the gamut from basic to translational to population research. | urogenital diseases, clinical therapies development |
lists: Cell Ranger lists: Human Tissue and Organ for Research Resource (HTORR) lists: GenitoUrinary Development Molecular Anatomy Project lists: Multi-Disciplinary Approach to the Study of Chronic Pelvic Pain lists: Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) lists: Prevention of Lower Urinary Tract Symptoms lists: Pediatric KIDney Stone Care Improvement Network lists: SBUR - Society for Basic Urologic Research lists: Society of Benign Prostate Disease lists: Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction (SUFU) lists: Research on Calculus Kinetics Society lists: American Urological Association lists: Endourological Society lists: NIDDK Information Network (dkNET) lists: Tissue Microarray Database lists: Stanford University School of Medicine O’Brien Urology Research Center Biospecimen/Bioimaging Core Facility lists: O'Brien Center for Benign Urologic Research at University of Wisconsin-Madision and University of Massachusetts-Boston lists: Columbia University George M. O'Brien Urology Center |
Free, Freely available | SCR_022876 | 2026-08-11 09:44:29 | 1 | |||||||||
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SOLVO Biotechnology Resource Report Resource Website 1+ mentions |
SOLVO Biotechnology (RRID:SCR_003964) | SOLVO | commercial organization | Commercial organization that is a worldwide provider of drug transporter technology, assays and reagents. Leveraging their expertise in efflux and uptake transporters, they generate quality reports for submission to FDA / EMA. From small molecules to protein therapeutics, SOLVO can test all transporter needs. Drug transporter Services and Products include: * Over 100 solutions for a wide range of transporters * Uptake transporter assays * Efflux transporter assays in cellular and membrane-based models * Transporter Consultancy Services * FDA- and EMA-ready reports * Ready-to-use Kits * In vitro and in vivo methods for studying transporters in the BBB, intestine, liver and kidney * Custom assay development | assay, membrane transporter, diagnostic, drug discovery, transporter, membrane | is related to: MIP-DILI | nlx_158367 | SCR_003964 | Solvo Biotechnology ZRT | 2026-08-08 11:58:13 | 2 | ||||||||
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Proteon Therapeutics Resource Report Resource Website 1+ mentions |
Proteon Therapeutics (RRID:SCR_004037) | Proteon | commercial organization | A biopharmaceutical company developing pharmaceuticals for patients with renal and vascular diseases. Their ongoing Phase 3 clinical trial is evaluating whether a single treatment of PRT-201 can reduce vascular access failure, one of the most serious problems experienced by patients with chronic kidney disease (CKD) undergoing hemodialysis. PRT-201 is an investigational drug that may inhibit neointimal hyperplasia, the growth of tissue inside blood vessels that can result in vessel narrowing and reduced blood flow. PRT-201 has received fast track and orphan drug designations for hemodialysis vascular access indications.In September 2019, Proteon Therapeutics merged with ArTara Therapeutics. | biopharmaceutical, pharmaceutical, hemodialysis, prt-201, drug |
is related to: Kidney Health Initiative is related to: Protara Therapeutics |
Kidney disease, Vascular disease, Chronic kidney disease, Neointimal hyperplasia, Peripheral arterial disease | nlx_158465 | SCR_004037 | Proteon Therapeutics Inc. | 2026-08-08 11:58:09 | 1 | |||||||
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Michigan Diabetes Research Center Resource Report Resource Website 1+ mentions |
Michigan Diabetes Research Center (RRID:SCR_015112) | MDRC | service resource, core facility, access service resource | Multidisciplinary unit of the University of Michigan funded by the National Institute of Diabetes and Digestive and Kidney Diseases/National Institute of Health. Promotes new discoveries and enhance scientific progress through the support of basic and clinical research related to diabetes, its complications, and related disorders. Creates environment that supports innovative research; attracts and retains early stage investigators and investigators new to diabetes research; provides core services that leverage funding and unique expertise; fosters interdisciplinary collaborations; raises awareness and interest in fundamental and clinical diabetes research at their institutions, as well as locally, regionally, and nationally. | clinical diabetes research, multidisciplinary research, endocrine and metabolic disorders, |
is listed by: NIDDK Information Network (dkNET) has organization facet: Michigan Diabetes Research Center Administrative Core Facility has organization facet: Michigan Diabetes Research Center Clinical Core Facility has organization facet: Michigan Diabetes Research Center Microscopy and Image Analysis Core Facility has organization facet: Michigan Diabetes Research Center Molecular Genetics Core Facility has organization facet: Michigan Diabetes Research Center Animal Studies Core is organization facet of: Diabetes Research Centers |
Diabetes | NIDDK P30DK020572 | Restricted | http://diabetesresearch.med.umich.edu | SCR_015112 | Michigan Diabetes Research Center (MDRC) | 2026-08-11 09:42:56 | 4 |
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