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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/devel/bioc/html/BEAT.html
Software that implements all bioinformatics steps required for the quantitative, high-resolution analysis of DNA methylation patterns from bisulfite sequencing data.
Proper citation: BEAT (RRID:SCR_002387) Copy
https://github.com/mpyatkov/sbars
Bioinformatics tool for searching different types of long repeats in sequences comparable by size with chromosomes.
Proper citation: SBARS (RRID:SCR_002371) Copy
http://personalpages.manchester.ac.uk/staff/mathias.nilsson/software.htm
Software toolbox for processing PFG NMR diffusion data that aims to incorporate many of the important processing schemes. It has a graphical user interface to make it easy to access a variety of different processing schemes (and a command mode for more advanced options). It is written in MATLAB, but can also be obtained as free standing compiled version that does not require a MATLAB installation. The MATLAB version runs on any platform, and the compiled version is presently available for Windows, Linux, and Mac.
Proper citation: DOSY Toolbox (RRID:SCR_002409) Copy
http://www.bioconductor.org/packages/release/bioc/html/CAMERA.html
A Bioconductor package integrating algorithms to extract compound spectra, annotate isotope and adduct peaks, and propose the accurate compound mass even in highly complex data.
Proper citation: CAMERA - Collection of annotation related methods for mass spectrometry data (RRID:SCR_002466) Copy
http://droog.gs.washington.edu/polyphred/
Software program that compares fluorescence-based sequences across traces obtained from different individuals to identify heterozygous sites for single nucleotide substitutions. Its functions are integrated with the use of three other programs: Phred (Brent Ewing and Phil Green), Phrap (Phil Green), and Consed (David Gordon and Phil Green). PolyPhred identifies potential heterozygotes using the base calls and peak information provided by Phred and the sequence alignments provided by Phrap. Potential heterozygotes identified by PolyPhred are marked for rapid inspection using the Consed tool.
Proper citation: PolyPhred (RRID:SCR_002337) Copy
http://cran.r-project.org/web/packages/isa2/
A biclustering algorithm that finds modules in an input matrix. A module or bicluster is a block of the reordered input matrix.
Proper citation: Iterative Signature Algorithm (RRID:SCR_002327) Copy
https://github.com/armintoepfer/haploclique
Software providing a computational approach to reconstruct the structure of a viral quasispecies from next-generation sequencing data as obtained from bulk sequencing of mixed virus samples.
Proper citation: HaploClique (RRID:SCR_002353) Copy
http://www.bioconductor.org/packages/devel/bioc/html/MethylAid.html
Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored.
Proper citation: MethylAid (RRID:SCR_002659) Copy
http://www.bioconductor.org/packages/release/bioc/html/wateRmelon.html
Software package for Illumina 450 methylation array normalization and metrics including 15 flavors of betas and three performance metrics, with methods for objects produced by methylumi, minfi and IMA packages.
Proper citation: wateRmelon (RRID:SCR_001296) Copy
http://sourceforge.net/projects/ngsrich/
Software for target enrichment performance for next-generation sequencing.
Proper citation: NGSrich (RRID:SCR_001333) Copy
https://www.bioconductor.org/packages//2.10/bioc/html/oneChannelGUI.html
Software library that provides a graphical interface for microarray gene and exon level analysis as well as miRNA/mRNA-seq data analysis. The package was developed to simplify the use of Bioconductor tools for beginners having limited or no experience in writing R code.
Proper citation: oneChannelGUI (RRID:SCR_001325) Copy
http://itb.biologie.hu-berlin.de/~futschik/software/R/cycle/index.html
Software package for the identification of periodically expressed genes using Fourier analysis and the statistical assessment of significance using different background models.
Proper citation: CYCLE (RRID:SCR_001328) Copy
https://www.bioconductor.org/packages//2.12/bioc/html/LMGene.html
Software package for Data Transformation and Identification of Differentially Expressed Genes in Gene Expression Arrays.
Proper citation: LMGene (RRID:SCR_001329) Copy
http://bioinf.wehi.edu.au/affylmGUI/
R software package providing a Graphical User Interface for analysis of Affymetrix microarray data, using the limma package (Linear Models for MicroArray data). While not as powerful as limma to the expert user, it offers a simple point-and-click interface to many of the commonly-used limma and affy functions. You need to have R 1.9.0 or later, Tcl/Tk 8.3 or later (ActiveTcl for Windows, Tcl/Tk Source for Linux/Unix, or X11 Tcl/Tk for MacOSX) and the limma, affylmGUI, and tkrplot R packages. It has been succesfully tested on Windows 2000, Windows XP, RedHat/Fedora Linux, and on Mac OSX with X11.
Proper citation: affylmGUI (RRID:SCR_001320) Copy
http://www.bioconductor.org/packages/release/bioc/html/arrayQuality.html
Software functions for performing print-run and array level quality assessment.
Proper citation: arrayQuality (RRID:SCR_001315) Copy
https://www.bioconductor.org/packages//2.10/bioc/html/ArrayTools.html
Software package for quality assessment and to detect differentially expressed genes for the Affymetrix GeneChips, including both 3' -arrays and gene 1.0-ST arrays. The package generates comprehensive analysis reports in HTML format. Hyperlinks on the report page will lead to a series of QC plots, processed data, and differentially expressed gene lists. Differentially expressed genes are reported in tabular format with annotations hyperlinked to online biological databases.
Proper citation: ArrayTools (RRID:SCR_001313) Copy
http://www.bioconductor.org/packages/release/bioc/html/affyPLM.html
Software for fitting probe-level models and tools using these models. Probe-level models (PLM) based quality assessment tools.
Proper citation: affyPLM (RRID:SCR_001319) Copy
http://www.bioconductor.org/packages/release/bioc/html/plgem.html
Software to detect differential expression in microarray and proteomics datasets. Its use has been shown to improve the detection of differentially expressed genes or proteins in these datasets.
Proper citation: plgem (RRID:SCR_001355) Copy
http://www.bioconductor.org/packages/release/bioc/html/pvca.html
Software package that contains the function to assess the batch sourcs by fitting all sources as random effects including two-way interaction terms in the Mixed Model (depends on lme4 package) to selected principal components, which were obtained from the original data correlation matrix. This package accompanies the book Batch Effects and Noise in Microarray Experiements, chapter 12.
Proper citation: PVCA (RRID:SCR_001356) Copy
http://www.bioconductor.org/packages/release/bioc/html/metaArray.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for data transformation for meta-analysis of microarray Data: Transformation of gene expression data to signed probability scale (MCMC/EM methods) and combined differential expression on raw scale: Weighted Z-score after stabilizing mean-variance relation within platform.
Proper citation: metaArray (RRID:SCR_001353) Copy
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