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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
National NeuroAIDS Tissue Consortium
 
Resource Report
Resource Website
10+ mentions
National NeuroAIDS Tissue Consortium (RRID:SCR_007323) NNTC biomaterial supply resource, brain bank, tissue bank, material resource Collects, stores, and distributes samples of nervous tissue, cerebrospinal fluid, blood, and other tissue from HIV-infected individuals. The NNTC mission is to bolster research on the effects of HIV infection on human brain by providing high-quality, well-characterized tissue samples from patients who died with HIV, and for whom comprehensive neuromedical and neuropsychiatric data were gathered antemortem. Researchers can request tissues from patients who have been characterized by: * degree of neurobehavioral impairment * neurological and other clinical diagnoses * history of drug use * antiretroviral treatments * blood and CSF viral load * neuropathological diagnosis The NNTC encourages external researchers to submit tissue requests for ancillary studies. The Specimen Query Tool is a web-based utility that allows researchers to quickly sort and identify appropriate NNTC specimens to support their research projects. The results generated by the tool reflect the inventory at a previous time. Actual availability at the local repositories may vary as specimens are added or distributed to other investigators. human immunodeficiency virus, nervous tissue, cerebral spinal fluid, blood, tissue, brain, neuromedical data, neuropsychiatric data, tissue, plasma, peripheral blood mononuclear cell, serum, urine, spinal cord, nervous tissue, pituitary gland, trigeminal ganglia, dorsal root ganglion, peripheral nerve, lymph node, liver, spleen, adipose tissue, bone marrow, muscle, hair, heart, thymus, kidney, lung, eye, brain, ante-mortem, post-mortem, normal, subsyndromic, minor cognitive motor disorder, hiv - associated dementia, cytomegalovirus encephalitis, neurological impairment, traumatic brain injury, neurocognitive disease, frozen, fixed, aids, one mind tbi, asymptomatic neurocognitive impairment, minor cognitive disorder, gene array, snp is listed by: One Mind Biospecimen Bank Listing
is related to: Manhattan HIV Brain Bank
is related to: CHARTER - CNS HIV Antiretroviral Therapy Effects Research
Human immunodeficiency virus, Neurocognitive disease, Normal, Subsyndromic, Minor Cognitive Motor Disorder, HIV - Associated Dementia, Cytomegalovirus Encephalitis, Neurological impairment, Infectious disease NIMH ;
NINDS ;
NIH Blueprint for Neuroscience Research
Public: The NNTC encourages external researchers to submit tissue requests for ancillary studies. nif-0000-00193 SCR_007323 nntc.org, nntc 2026-08-11 09:41:33 13
Life Extension: Laboratory and Blood Testing Services
 
Resource Report
Resource Website
Life Extension: Laboratory and Blood Testing Services (RRID:SCR_007167) service resource, analysis service resource, production service resource, material analysis service, biomaterial analysis service Blood testing is the single most important preventive tool you can use to help head off health problems. Life Extension makes it possible to take advantage of that tool at a fraction of the cost commercial blood labs charge. Get a picture of your overall health. Identify potential disease risks. Test for specific problems with comprehensive blood test panels and individualized tests like these: * Male and Female Comprehensive Panels * Cardiac Risk Factors * Vitamin Deficiencies * Hormone and Thyroid Panels * Metabolic and Chemistry Profiles blood, test, health, laboratory, cardiac, risk, male, female, vitamin deficiency, hormone, thyroid, metabolic, chemistry, cancer, heart, kidney, infections, immune, allergies, urinary, panel has parent organization: Life Extension Life Extension Foundation nif-0000-30206 SCR_007167 Blood Testing Services 2026-08-11 09:41:31 0
Mayo Clinic O'Brien Urology Center Biostatistics and Epidemiology Core
 
Resource Report
Resource Website
Mayo Clinic O'Brien Urology Center Biostatistics and Epidemiology Core (RRID:SCR_015452) service resource, core facility, access service resource, resource Core that is responsible for all statistical, data management and epidemiological aspects of studies in the Mayo Clinic O'Brien Urology Research Center. Its services include consultation to project investigators regarding study design, data analysis and interpretation of results, maintanence of the Olmsted County kidney stone database, and development of additional linkable databases and quality control procedures. nephrolithiasis, statistical analysis, epidemiology, data management is listed by: NIDDK Information Network (dkNET)
has parent organization: Mayo Clinic
has parent organization: Mayo Clinic O'Brien Urology Center
is organization facet of: Mayo Clinic O'Brien Urology Center
NIDDK U54DK100227 Available to the O'Brien Urology Research Center community SCR_015452 2026-08-11 09:43:09 0
The Li Lab at UCSF
 
Resource Report
Resource Website
100+ mentions
The Li Lab at UCSF (RRID:SCR_010269) data or information resource, database Laboratory portal that houses the following databases. MethPrimer is a program for designing bisulfite-conversion-based Methylation PCR Primers. Currently, it can design primers for two types of bisulfite PCR: 1) Methylation-Specific PCR (MSP) and 2) Bisulfite-Sequencing PCR (BSP) or Bisulfite-Restriction PCR. CpG Island Prediction MethPrimer can also analyze input sequences for the existence of CpG islands. Human Prostate Gene Database (PGDB) is a curated and integrated database of human genes related to the prostate and prostatic diseases. Human Kidney Gene Database (KGDB) is a curated and integrated database of human genes related to the kidney and renal diseases. The Li Lab is interested in understanding how small RNA regulates gene expression at the transcriptional level by targeting gene promoter sequences, particularly how small RNA activates gene transcription, a phenomenon termed RNA activation (RNAa). has parent organization: University of California at San Francisco; California; USA nlx_156928 SCR_010269 The Li Lab in the Department of Urology and Helen Diller Family Comprehensive Cancer Center, UCSF 2026-08-10 09:33:57 195
Nephrotic Syndrome Study Network (NEPTUNE)
 
Resource Report
Resource Website
Nephrotic Syndrome Study Network (NEPTUNE) (RRID:SCR_014380) NEPTUNE data or information resource, data set A consortium of researchers conducting a cohort study that investigates the underlying disease mechanisms of pro non-inflammatory glomerular diseases. The aim is to elucidate pathogenesis and identify therapeutic targets for clinical trials. The study participants will be classified according to the kidney biopsy results into one of three subcohorts, including Minimal change disease/Focal segmental glomerulosclerosis; Membranous nephropathy; and other conditions. cohort study, pro non inflammatory glomerular disease, consortium, disease mechanism, pathogenesis, clinical trial, kidney is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
Kidney diseases, Nephrotic syndrome, Renal insufficiency, Chronic, Minimal change disease/Focal segmental glomerulosclerosis, Membranous nephropathy Study is ongoing, Publications are available http://www.niddk.nih.gov/research-funding/research-resources/Pages/default.aspx SCR_014380 Nephrotic Syndrome Study Network 2026-08-08 12:06:19 0
Nephropath
 
Resource Report
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1+ mentions
Nephropath (RRID:SCR_003995) Nephropath commercial organization Commercial service interpreting renal biopsies using 14 board-certified, fellowship-trained pathologists with decades of experience. They provide doctors with a high quality, clinico-pathologic discussion by the pathologist that read the case. It is their goal to help equip doctors with the results they need to deliver the most effective patient care possible. That is why they deliver same-day biopsy results, including EM, because they know that time often has a critical effect on the outcome of many renal diseases. Nephropath also offers PLA2R serum testing and will soon be offering neuropathology services including muscle and nerve biopsy services.Nephropath is now Arkana Laboratories. pathology, neuropathology, muscle, nerve, biopsy service, pathologist, kidney, biopsy, renal, serum, neurology is related to: Kidney Health Initiative Kidney disease nlx_158408 SCR_003995 2026-08-08 11:58:14 1
Arbor Research Collaborative for Health
 
Resource Report
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1+ mentions
Arbor Research Collaborative for Health (RRID:SCR_003972) Arbor Research nonprofit organization A not-for-profit research organization committed to improve patient care through research that shapes medical policies and practice. In particular, they conduct health outcomes research on chronic disease and end-stage organ failure, with expertise in biostatistical analysis, clinical practice, health economics, public policy, database management and integration, and project coordination. Through research projects that are national and global in scope, their scientific collaborations provide valuable and timely information to the worldwide health care community. They are a leader in interdisciplinary health outcomes and policy research focused on reducing the health and economic burden of chronic diseases and improving the delivery of care. health outcome, patient care, clinical, policy, nephrology, statistics, kidney, transplant, dialysis, epidemiology, public health, clinical practice, policy development, medical payment system is related to: Kidney Health Initiative Kidney disease, Organ failure, Chronic disease grid.413857.c, nlx_158379, ISNI: 0000 0004 0628 9837 https://ror.org/043qmbk61 SCR_003972 URREA, University Renal Research and Education Association 2026-08-08 11:58:11 3
American Nephrology Nurses Association
 
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1+ mentions
American Nephrology Nurses Association (RRID:SCR_003966) ANNA institution Non-profit professional association that represents nurses who work in all areas of nephrology including hemodialysis, chronic kidney disease, peritoneal dialysis, acute care, and transplantation. Most members work in freestanding dialysis units, hospital outpatient units, and hospital inpatient units. ANNA develops and updates standards of clinical practice, educates practitioners, stimulates and supports research, disseminates knowledge and new ideas, promotes interdisciplinary communication and cooperation, and monitors and addresses issues encompassing the breadth of practice of nephrology nursing. clinical, kidney, nephrology, nurse, health care, dialysis, journal, training resource is related to: Nephrology Nursing Certification Commission
is related to: Kidney Health Initiative
Kidney disease grid.469735.a, nlx_158371, ISNI: 0000 0000 9310 7210, Crossref funder ID: 100005526 https://ror.org/05a8c4g41 SCR_003966 American Nephrology Nurses'' Association 2026-08-08 11:58:11 1
U.S. Pig Genome Project
 
Resource Report
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U.S. Pig Genome Project (RRID:SCR_008151) data or information resource, topical portal, portal, database Database and resources on the pig genome. embryo, embryonic, environmental, exercise, exposure, fat, feed, feeding, fibroblast, food, foot and mouth disease, function, genetic, acute, additive, alcohol, alcoholism, atherosclerosis, bed, behavior, biological, bone, breed, cancer, cell, chronic, clone, degenerative, density, deposition, dermal, developmental, diabetes, dietary, digestive, disease, genome, genomic, growth, habit, healing, human, hypertension, kidney, mammal, map, melanoma, metabolism, nephropathy, nuclear, nutrition, obesity, omnivore, organ, organism, parenteral, pathogen, pattern, phenotype, phenotypic, physiology, pig, pollutant, population, porcine, prenatal, pulmonary, reproductive, respiratory, retinal, sex, shock, size, social, somatic, structure, swine, taxon, technique, tissue, tobacco, transplantation, variation, vascular, warfare, xenobiotic, model is listed by: 3DVC nif-0000-20986 SCR_008151 U.S. Pig Genome Project 2026-08-10 09:33:26 0
Nephromine
 
Resource Report
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10+ mentions
Nephromine (RRID:SCR_003813) data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE; REPLACED BY NEPHROSEQ; A growing database of publicly available renal gene expression profiles, a sophisticated analysis engine, and a powerful web application designed for data mining and visualization of gene expression. It provides unique access to datasets from the Personalized Molecular Nephrology Research Laboratory incorporating clinical data which is often difficult to collect from public sources and mouse data. kidney, gene expression, visualization, clinical, expression profile, gene, mouse model, microarray is listed by: NIDDK Information Network (dkNET)
is related to: Nephroseq
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: Life Technologies
Kidney disease, Healthy, Lupus nephritis, Chronic kidney disease, Diabetic nephropathy THIS RESOURCE IS NO LONGER IN SERVICE nlx_158114 SCR_003813 2026-08-10 09:32:06 20
Collecting Duct Database
 
Resource Report
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Collecting Duct Database (RRID:SCR_000759) CDDB data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. This database is intended to serve as a learning tool to obtain curated information for the design of microarray targets to scan collecting duct tissues (human, rat, mouse). The database focuses on regulatory and transporter proteins expressed in the collecting duct, but when collecting duct proteins are a member of a larger family of proteins, common additional members of the family are included even if they have not been demonstrated to be expressed in the collecting duct. An Internet-accessible database has been devised for major collecting duct proteins involved in transport and regulation of cellular processes. The individual proteins included in this database are those culled from literature searches and from previously published studies involving cDNA arrays and serial analysis of gene expression (SAGE). Design of microarray targets for the study of kidney collecting duct tissues is facilitated by the database, which includes links to curated base pair and amino acid sequence data, relevant literature, and related databases. Use of the database is illustrated by a search for water channel proteins, aquaporins, and by a subsequent search for vasopressin receptors. Links are shown to the literature and to sequence data for human, rat, and mouse, as well as to relevant web-based resources. Extension of the database is dynamic and is done through a maintenance interface. This permits creation of new categories, updating of existing entries, and addition of new ones. CDDB is a database that organizes lists of genes found in collecting duct tissues from three mammalian species: human, rat, and mouse. Proteins are divided into categories by family relationships and functional classification, and each category is assigned a section in the database. Each section includes links to the literature and to sequence information for genes, proteins, expressed sequence tags, and related information. The user can peruse a section or use a search engine at the bottom of the web page to search the database for a name or abbreviation or for a link to a sequence. Each entry in the database includes links to relevant papers in the kidney and collecting duct literature. It uses links to PubMed to generate MEDLINE searches for retrieval of references. In addition, each entry includes links to curated sequence data available in LocusLink. Individual links are made to sequence and protein data for human, rat, and mouse. Links are then added as curated sequences become available for proteins identified in the renal collecting duct and for proteins identified in kidney and similar in function or homologous to proteins identified in the collecting duct. expressed sequence tag, expression, family, functional, gene, aquaporin, array, cdna, classification, collecting duct, homologous, human, kidney, literature, mammal, mammalian, microarray, mouse, protein, protein localization and targeting databases, rat, receptor, regulatory, relationship, scan, serial analysis, specie, target, tissue, transporter, vasopressin, water channel protein has parent organization: National Institutes of Health THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-21078 SCR_000759 Collecting Duct Database 2026-08-10 09:31:15 0
PSTC Nephrotoxicity Biomarkers
 
Resource Report
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PSTC Nephrotoxicity Biomarkers (RRID:SCR_003709) PSTC Nephrotoxicity Biomarkers data or information resource, standard specification, narrative resource Urinary kidney biomarkers (KIM-1, albumin, total protein, 2-microglobulin, cystatin C, clusterin and trefoil factor-3) that are considered acceptable biomarkers for the detection of acute drug-induced nephrotoxicity in rats and can be included along with traditional clinical chemistry markers and histopathology in toxicology studies. These biomarkers may be used voluntarily as additional evidence of nephrotoxicity in nonclinical safety assessment studies to complement the standard data (BUN and sCr). In ROC analyses, some of these biomarkers showed better sensitivity and specificity than BUN and sCr relative to histopathological alterations considered to be the gold standard when tested with a limited number of nephrotoxicant and control compounds. biomarker, drug development, drug, urinary, urinary biomarker, gold standard, kim-1, albumin, total protein, beta2-microglobulin, cystatin c, clusterin, trefoil factor-3, kidney, nonclinical is recommended by: U.S. Food and Drug Administration
has parent organization: Drug Development Tools Qualification Programs
has parent organization: Predictive Safety Testing Consortium
Nephrotoxicity, Drug-induced nephrotoxicity Public nlx_157890 SCR_003709 Predictive Safety and Testing Consortium Drug-induced Nephrotoxicity Biomarkers, PSTC NWG Drug-induced Nephrotoxicity Biomarkers 2026-08-11 09:40:49 0
ShARM
 
Resource Report
Resource Website
1+ mentions
ShARM (RRID:SCR_003120) ShARM biomaterial supply resource, tissue bank, material resource A not for profit organization to accelerate research into aging by sharing resources: providing access to cost and time effective, aged murine tissue through a biorepository and database of live ageing colonies, as well as promoting the networking of researchers and dissemination of knowledge through its online collaborative environment; MiCEPACE. ShARM will provide valuable resources for the scientific community while helping to reduce the number of animals used in vital research into aging. The biobank of tissue and networking facility will enable scientists to access shared research material and data. By making use of collective resources, the number of individual animals required in research experiments can be minimized. The project also has the added value of helping to reduce the costs of research by connecting scientists, pooling resource and combining knowledge. ShARM works in partnership with MRC Harwell and the Centre for Intergrated Research into Musculoskeletal Ageing (CIMA). data sharing, female, male, gut, heart, kidney, livers, lung, mammary fat, muscle, pancreas, bat, bladder, bone, brain, femur, skin, spleen, thymus, tibia, wat, aged tissue, aged mouse, murine model is listed by: One Mind Biospecimen Bank Listing Aging, Control, Young control Wellcome Trust PMID:24085518 Free, Freely available nlx_156767 SCR_003120 Shard Ageing Research Models 2026-08-11 09:40:40 4
Human Tissue and Organ for Research Resource (HTORR)
 
Resource Report
Resource Website
Human Tissue and Organ for Research Resource (HTORR) (RRID:SCR_002859) HTORR biomaterial supply resource, tissue bank, material resource NDRI’s Human Tissue and Organs for Research Resource (HTORR) Program has been funded by the National Institutes of Health (NIH) for over 30 consecutive years to support research programs across multiple disciplines. It is through the HTORR program that NDRI provides academic biomedical investigators with donated normal and diseased human tissues and organs recovered from a diverse donor pool using customized procurement, processing, and preservation and distribution protocols. Our HTORR Program supports academic biomedical research investigators needs by providing: Access to a wide array of human biospecimens from any body system * Customized procurement in a variety of preservation formats including fresh, frozen, and fixed suitable for various analytical techniques * Reduced costs for tissue procurement * Technical support to design your studies utilizing human biospecimens * Letters of support and budgetary information for grant applications tissue, organ, nervous system, pulmonary system, cardiovascular system, endocrine system, eye, bone, cartilage, normal, diseased, human immunodeficiency virus, heart, kidney, lung, brain, liver, eye, bone, joint, disease, rare disease, endocrinology, eye bank, immunology, infectious disease, nephrology, nervous system, ophthalmology, pathology, pulmonary system, research, specimen, toxicology, transplantation, catalog is listed by: One Mind Biospecimen Bank Listing
is listed by: Collaborating for the Advancement of Interdisciplinary Research in Benign Urology
has parent organization: National Disease Research Interchange
has parent organization: National Center for Research Resources
Normal, Disease, Human immunodeficiency virus, Rare disease NIH Office of the Director U42 OD011158 Free, Freely available nif-0000-25417 https://orip.nih.gov/comparative-medicine/programs/genetic-biological-and-information-resources http://www.ncrr.nih.gov/clinical%5Fresearch%5Fresources/resource%5Fdirectory/human_tissue_and_organ_resource_for_research/ SCR_002859 Human Tissue Organ Resource for Research, Human Tissues and Organs for Research, Human Tissues and Organs for Research (HTOR), Human Tissues Organs for Research 2026-08-11 09:40:38 0
Boston University Biospecimen Archive Research Core
 
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1+ mentions
Boston University Biospecimen Archive Research Core (RRID:SCR_005363) BU BARC biomaterial supply resource, tissue bank, material resource Biospecimen repository of normal and diseased human material from a variety of tissues and conditions along with clinical annotation. Both frozen aliquots and paraffin embedded tissue are available. Biospecimens are available to qualified researchers with IRB approval. * Preliminary inquires please contact Cheryl Spencer at cheryl.spencer (at) bmc.org disease, normal, cancer, tumor, colon, inflammatory bowel disease, rectal cancer, colon cancer, tonsil, obstructive sleep apnea, tonsillitis, parathyroid, parathyroid adenoma, stomach, stomach cancer, prostate, prostate cancer, uterus, uterine cancer, lung, squamous cell carcinoma, adenocarcinoma, ovary, ovarian cancer, thyroid, thyroid papillary carcinoma, kidney, papillary renal cell carcinoma, renal cell carcinoma, clear cell carcinoma, breast, ductal carcinoma in situ, invasive ductal carcinoma, invasive lobular carcinoma, tissue, cancer tissue, colon tissue, tonsil tissue, parathyroid tissue, stomach tissue, prostate tissue, uterine tissue, lung tissue, ovarian tissue, thyroid tissue, kidney tissue, breast tissue, frozen, paraffin block, blood, biopsy, heart disease, diabetes, brain, brain tissue, adrenal, adrenal tissue, parotid, parotid tissue, thymus, pancreas, cervix, esophagus, thymus tissue, pancreatic tissue, cervical tissue, esophageal tissue is listed by: One Mind Biospecimen Bank Listing
has parent organization: Boston University Medical Campus; Massachusetts; USA
has parent organization: Boston University School of Medicine; Massachusetts; USA
Disease, Cancer, Tumor, Normal, Heart disease, Diabetes, Inflammatory bowel disease, Rectal cancer, Colon cancer, Obstructive sleep apnea, Tonsillitis, Parathyroid adenoma, Stomach cancer, Prostate cancer, Uterine cancer, Squamous cell carcinoma, Adenocarcinoma, Ovarian cancer, Thyroid papillary carcinoma, Papillary renal cell carcinoma, Renal cell carcinoma, Clear cell carcinoma, Ductal carcinoma in situ, Invasive ductal carcinoma, Invasive lobular carcinoma Public: The mission of the Biospecimen Archive Research Core (BARC) is to collect high quality samples of normal and diseased human material with appropriate clinical annotation and make these materials, Known as biospecimens, Available to qualified researchers while ensuring the informed consent, Safety and anonymity of all providers. nlx_144430 SCR_005363 BU Biospecimen Archive Research Core, Boston University Biospecimen Archive Research Core (BARC), Biospecimen Archive Research Core Boston University Medical Center, Boston University Medical Center Biospecimen Archive Research Core, BUMC BARC, BUMC Biospecimen Archive Research Core 2026-08-11 09:41:17 1
Family Investigation of Nephropathy of Diabetes
 
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Family Investigation of Nephropathy of Diabetes (RRID:SCR_001525) FIND, F.I.N.D. clinical trial, resource Multicenter observational study designed to identify genetic determinants of diabetic nephropathy. It is conducted in eleven U.S. clinical centers and a coordinating center, and with four ethnic groups (European Americans, African Americans, Mexican Americans, and American Indians). Two strategies are used to localize susceptibility genes: a family-based linkage study and a case-control study using mapping by admixture linkage disequilibrium (MALD). In the family-based study, probands with diabetic nephropathy are recruited with their parents and selected siblings. Linkage analyses will be conducted to identify chromosomal regions containing genes that influence the development of diabetic nephropathy or related quantitative traits such as serum creatinine concentration, urinary albumin excretion, and plasma glucose concentrations. Regions showing evidence of linkage will be examined further with both genetic linkage and association studies to identify genes that influence diabetic nephropathy or related traits. Two types of MALD studies are being done. One is a case-control study of unrelated individuals of Mexican American heritage in which both cases and controls have diabetes, but only the case has nephropathy. The other is a case-control study of African American patients with nephropathy (cases) and their spouses (controls) unaffected by diabetes and nephropathy; offspring are genotyped when available to provide haplotype data. The specific goals of this program: * Delineate genomic regions associated with the development and progression of renal disease(s) * Evaluate whether there is a genetic link between diabetic nephropathy and diabetic retinopathy * Improve outcomes * Provide protection for people at risk and slow the progression of renal disease * Help establish a resource for genetic studies of kidney disease and diabetic complications by creating a repository of genetic samples and a database * Encourage studies of the genetics of progressive renal disease genetic susceptibility, genetic pathway, renal, kidney, outcome, gene, genetics, european-american, african-american, mexican-american, american-indian, linkage association study, admixture linkage disequilibrium, mapping by admixture linkage disequilibrium, serum creatinine, urinary protein excretion, plasma glucose level, blood pressure, blood lipid level, trait, linkage, adult human, male, female, clinical is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
NIDDK 5R01DK053591 PMID:15642484 Free, Freely available nlx_152825 https://www.niddkrepository.org/studies/find/ SCR_001525 Family Investigation of Nephropathy and Diabetes (F.I.N.D.), Family Investigation of Nephropathy & Diabetes 2026-08-11 09:40:22 0
RiVuR
 
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1+ mentions
RiVuR (RRID:SCR_001539) RIVUR clinical trial, resource Multicenter, randomized, double-blind, placebo-controlled trial is designed to determine whether daily antimicrobial prophylaxis is superior to placebo in preventing recurrence of urinary tract infection (UTI) in children with vesicoureteral reflux (VUR). The basic eligibility criteria are: (1) age at randomization of at least 2 months, but less than 6 years, (2) a diagnosed first febrile or symptomatic UTI within 42 days prior to randomization that was appropriately treated, and (3) presence of Grade I-IV VUR based on voiding cystourethrogram (VCUG). Patients will be randomly assigned to treatment for 2 years with daily antimicrobial prophylaxis (trimethoprim-sulfamethoxazole) or placebo. The study is designed to recruit 600 children (approximately 300 in each treatment group) over an 18-24 month period. The primary endpoint is recurrence of UTI. In addition, patients will be evaluated for secondary endpoints related to renal scarring and antimicrobial resistance. Scarring will be determined based on renal scintigraphy by 99mTc dimercaptosuccinic (DMSA) scan. Quality of life, compliance, safety parameters, utilization of health resources, and change in VUR will be assessed periodically throughout the study. child, antimicrobial prophylaxis, placebo, antibiotic, renal scarring, pediatric, trimethoprim-sulfamethoxazole, intervention, kidney, antibiotic resistance, young human, infant, bibliography, clinical, trimethoprim, sulfamethoxazole is listed by: ClinicalTrials.gov
is listed by: NIDDK Information Network (dkNET)
is listed by: NIDDK Research Resources
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
Vesico-ureteral reflux, Urinary tract infection NIDDK PMID:19570724
PMID:19018048
PMID:18076937
PMID:19018047
PMID:19086141
Free, Freely available nlx_152848 http://www.cscc.unc.edu/rivur/ SCR_001539 Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR), Randomized Intervention for Children with Vesicoureteral Reflux, Randomized Intervention for Vesicoureteral Reflux 2026-08-11 09:40:22 1
NIH Office of Science Education
 
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NIH Office of Science Education (RRID:SCR_005603) OSE portal, data or information resource, narrative resource, knowledge environment, training material, organization portal The NIH Office of Science Education (OSE) coordinates science education activities at the NIH and develops and sponsors science education projects in house. These programs serve elementary, secondary, and college students and teachers and the public. Activities * Develop curriculum supplements and other educational materials related to medicine and research through collaborations with scientific experts at NIH * Maintain a website as a central source of information about NIH science education resources * Establish national model programs in public science education, such as the NIH Mini-Med School and Science in the Cinema * Promote science education reform as outlined in the National Science Education Standards and related guidelines The OSE was established in 1991 within the Office of Science Policy of the Office of the Director of the National Institutes of Health. The NIH is the world''s foremost biomedical research center and the U.S. federal government''s focal point for such research. It is one of the components of the Department of Health and Human Services (HHS). The Office of Science Education (OSE) plans, develops, and coordinates a comprehensive science education program to strengthen and enhance efforts of the NIH to attract young people to biomedical and behavioral science careers and to improve science literacy in both adults and children. The function of the Office is as follows: (1) develops, supports, and directs new program initiatives at all levels with special emphasis on targeting students in grades kindergarten to 16, their educators and parents, and the general public; (2) advises NIH leadership on science education issues; (3) examines and evaluates research and emerging trends in science education and literacy for policy making; (4) works closely with the NIH extramural, intramural, women''s health, laboratory animal research, and minority program offices on science education special issues and programs to ensure coordination of NIH efforts; (5) works with NIH institutes, centers, and divisions to enhance communication of science education activities; and (6) works cooperatively with other public- and private-sector organizations to develop and coordinate activities. science, education, high school, middle school, elementary school, animal, research, bioethics, blood, lymphatic system, bones, joints, muscle, brain, nervous system, cell biology, cancer, child, adolescent, complementary medicine, alternative medicine, digestive system, ears, nose, throat, endocrine system, environmental, toxicology, evolution, eye, vision, food, nutrition, metabolism, genomics, genetics, heart, circulation, history, immune system, injury, wound, kidney, urinary system, medical research, man, mental health, behavior, microbiology, infectious disease, mouth, teeth, therapy, reproductive system, respiratory system, safety, late adult human, sexual health, skin, hair, nail, sleep, social, family, substance abuse, technology, wellness, lifestyle, woman, health, human, lesson plan, supplemental curricula, book, image, multimedia, poster, k-12, adult, non-human animal has parent organization: National Institutes of Health
is parent organization of: NIH SciEd Blog
NIH nlx_146222 SCR_005603 NIH OSE, National Institutes of Health Office of Science Education 2026-08-11 09:41:09 0
Creatinine Standardization Program
 
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Resource Website
1+ mentions
Creatinine Standardization Program (RRID:SCR_006441) Creatinine Standardization Program international standard specification, experimental protocol, data or information resource, resource, narrative resource, standard specification Standard specification to reduce inter-laboratory variation in creatinine assay calibration and therefore enable more accurate estimates of glomerular filtration rate (eGFR). Created by NKDEP''''s Laboratory Working Group in collaboration with the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) and the European Communities Confederation of Clinical Chemistry (now called the European Federation of Clinical Chemistry and Laboratory Medicine), the effort is part of a larger NKDEP initiative to help health care providers better identify and treat chronic kidney disease in order to prevent or delay kidney failure and improve patient outcomes. Recommendations are intended for the USA and other countries or regions that have largely completed standardization of creatinine calibration to be traceable to an isotope dilution mass spectrometry (IDMS) reference measurement procedure. The program''''s focus is to facilitate the sharing of information to assist in vitro diagnostic manufacturers, clinical laboratories, and others in the laboratory community with calibrating their serum creatinine measurement procedures to be traceable to isotope dilution mass spectrometry (IDMS). The program also supports manufacturers'''' efforts to encourage their customers in the laboratory to coordinate use of standardized creatinine methods with implementation of a revised GFR estimating equation appropriate for use with standardized creatinine methods. Communication resources and other information for various segments of the laboratory community are available in the Creatinine Standardization Recommendations section of the website. Also available is a protocol for calibrating creatinine measurements using whole blood devices. The National Institute for Standards and Technology (NIST) released a standard reference material (SRM 967 Creatinine in Frozen Human Serum) for use in establishing calibrations for routine creatinine measurement procedures. SRM 967 was validated to be commutable with native serum samples for many routine creatinine procedures and is useful to establish or verify traceability to an IDMS reference measurement procedure. Establishing calibrations for serum creatinine methods using SRM 967 not only provides a mechanism for ensuring more accurate measurement of serum creatinine, but also enables more accurate estimates of GFR. For clinical laboratories interested in independently checking the calibration supplied by their creatinine reagent suppliers/manufacturers, periodic measurement of NIST SRM 967 should be considered for inclusion in the lab''''s internal quality assurance program. To learn more about SRM 967, including how to purchase it, visit the NIST website, https://www-s.nist.gov/srmors/quickSearch.cfm creatinine, estimate, glomerular filtration rate, kidney, isotope dilution mass spectrometry, whole blood, calibration, serum, serum creatinine, clinical is related to: Glomerular Filtration Rate Calculators
is related to: NIDDK Information Network (dkNET)
is related to: NIST - National Institute of Standards and Technology
has parent organization: National Kidney Disease Education Program
Chronic kidney disease NIDDK nlx_152736 SCR_006441 2026-08-11 09:41:24 2
Morpholino Database
 
Resource Report
Resource Website
1+ mentions
Morpholino Database (RRID:SCR_001378) MODB service resource, data or information resource, storage service resource, database, data repository Central database to house data on morpholino screens currently containing over 700 morpholinos including control and multiple morpholinos against the same target. A publicly accessible sequence-based search opens this database for morpholinos against a particular target for the zebrafish community. Morpholino Screens: They set out to identify all cotranslationally translocated genes in the zebrafish genome (Secretome/CTT-ome). Morpholinos were designed against putative secreted/CTT targets and injected into 1-4 cell stage zebrafish embryos. The embryos were observed over a 5 day period for defects in several different systems. The first screen examined 184 gene targets of which 26 demonstrated defects of interest (Pickart et al. 2006). A collaboration with the Verfaillie laboratory examined the knockdown of targets identified in a comparative microarray analysis of hematopoietic stem cells demonstrating how microarray and morpholino technologies can be used in conjunction to enrich for defects in specific developmental processes. Currently, many collaborations are underway to identify genes involved in morphological, kidney, skin, eye, pigment, vascular and hematopoietic development, lipid metabolism and more. The screen types referred to in the search functions are the specific areas of development that were examined during the various screens, which include behavior, general morphology, pigmentation, toxicity, Pax2 expression, and development of the craniofacial structures, eyes, kidneys, pituitary, and skin. Only data pertaining to specific tests performed are presented. Due to the complexity of this international collaboration and time constraints, not all morpholinos were subjected to all screen types. They are currently expanding public access to the database. In the future we will provide: * Mortality curves and dose range for each morpholino * Preliminary data regarding the effectiveness of each morpholino * Expanded annotation for each morpholino * External linkage of our morpholino sequences to ZFIN and Ensembl. To submit morpholino-knockdown results to MODB please contact the administrator for a user name and password. morpholino, target mrna, embryonic zebrafish, sequence, target, blast, phenotype, anatomy, development, behavior, morphology, pigmentation, toxicity, pax2 expression, craniofacial structure, eye, kidney, pituitary, skin, name, target name, target sequence, gene target, genetic, mortality, toxicity, defect, function, gene annotation, genome, data analysis service uses: Zebrafish Information Network (ZFIN)
uses: PATO
has parent organization: Mayo Clinic Minnesota; Minnesota; USA
NIGMS GM63904;
NIA CA65493
PMID:18179718 THIS RESOURCE IS NO LONGER IN SERVICE nlx_152566 SCR_001378 MODB (MOprholino DataBase) 2026-08-11 09:40:19 1

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