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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.wf4ever-project.org/
Project to addresses challenges associated with the preservation of scientific experiments in data-intensive science, including: * The definition of models to describe, in a standard way, scientific experiments by means of workflow-centric Research Objects, which comprise scientific workflows, the provenance of their executions, interconnections between workflows and related resources (e.g., datasets, publications, etc.), and social aspects related to such scientific experiments. * The collection of best practices for the creation and management of Research Objects. * The analysis and management of decay in scientific workflows. To address these challenges they are creating an architecture and tooling for the access, manipulation, sharing, reuse and evolution of Research Objects in a range of disciplines. This will result into the next generation RO-enabled myExperiment.
Proper citation: Workflow4Ever (RRID:SCR_005939) Copy
Public research university in Denton, Texas.
Proper citation: University of North Texas; Texas; USA (RRID:SCR_005935) Copy
An Antibody supplier
Proper citation: ReproCELL Incorporated (RRID:SCR_005973) Copy
http://www.nitrc.org/projects/bash-rs-fcmri
THIS RESOURCE IS NO LONGER IN SERVICE, documented July 23, 2015. Of note: most functions have been integrated in 1000 Functional Connectomes Project (www.nitrc.org/projects/fcon_1000). This package is not updated, thus please visit 1000 Functional Connectomes Project site and download relevant bash scripts. BASH Scripts for a resting-state functional MRI study. The functions include seed-based correlation analysis, amplitude analysis and independent component analysis. Note: this tool is just a plug-in for FSL, AFNI and FreeSurfer. Thus, you need have them before you use BASH4RfMRI.
Proper citation: BASH4RfMRI (RRID:SCR_005970) Copy
The mission of the Doris Duke Charitable Foundation is to improve the quality of people''s lives through grants supporting the performing arts, environmental conservation, medical research and the prevention of child abuse, and through preservation of the cultural and environmental legacy of Doris Duke''s properties. Established in 1996, the foundation supports four national grant-making programs. It also supports three properties that were owned by Doris Duke in Hillsborough, New Jersey; Honolulu, Hawaii; and Newport, Rhode Island. The foundation is headquartered in New York and is governed by a board of 12 Trustees. DDCF''s activities are guided by the will of Doris Duke, who endowed the foundation with financial assets that totaled approximately $1.6 billion as of December 31, 2010. The foundation regularly evaluates and modifies its allocation of resources from the endowment to support the programs and properties and to respond to fluctuations in portfolio returns. The foundation awarded its first grants in 1997. As of December 31, 2011, the foundation has awarded grants totaling more than $1 billion. DDCF awards grants in four core program areas: * The Arts Program supports performing artists with the creation and public performance of their work. * The Environment Program supports efforts that enable communities to protect and manage wildlife habitat and create efficient built environments. * The Medical Research Program seeks to contribute to the prevention and cure of disease by supporting clinical research. * The Child Abuse Prevention Program seeks to protect children from abuse and neglect in order to promote their healthy development. In the fall of 2007, DDCF also launched the African Health Initiative, with the goal of strengthening health systems in sub-Saharan Africa. The Building Bridges Program, which seeks to increase public understanding of Islamic cultures through media and the arts, is funded through the Doris Duke Foundation for Islamic Art and is headquartered in DDCF''s offices in New York. The Properties In her will, Doris Duke requested that several operating foundations manage the properties listed below. She also expressed her wishes that the properties be opened for public visitation and used for educational programs. The operating foundations receive funding from the Doris Duke Charitable Foundation. * The Duke Farms Foundation manages a 2,700-acre property in Hillsborough, New Jersey, which is known as Duke Farms and has a mission of environmental stewardship. * The Doris Duke Foundation for Islamic Art manages Doris Duke''s home in Honolulu, Hawaii, which is known as Shangri La and serves as a center for the study of Islamic art and cultures. * The Newport Restoration Foundation preserves historic houses in Newport, Rhode Island, and operates Doris Duke''s home in Newport known as Rough Point, which is also a public museum.
Proper citation: Doris Duke Charitable Foundation (RRID:SCR_006012) Copy
An Antibody supplier
Proper citation: NOVA Biologics (RRID:SCR_005985) Copy
http://www.bioconductor.org/packages/devel/bioc/html/deepSNV.html
Software package that provides quantitative variant callers for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. The algorithm is used for a comparative setup with a control experiment of the same loci and uses a beta-binomial model and a likelihood ratio test to discriminate sequencing errors and subclonal SNVs (single nucleotide variants).
Proper citation: deepSNV (RRID:SCR_006214) Copy
http://www.semantic-mediawiki.org/wiki/Semantic_MediaWiki
A free, open-source extension to MediaWiki - the wiki software that powers Wikipedia - that helps to search, organize, tag, browse, evaluate, and share the wiki''s content. While traditional wikis contain only text which computers can neither understand nor evaluate, SMW adds semantic annotations that allow a wiki to function as a collaborative database. Semantic MediaWiki introduces some additional markup into the wiki-text which allows users to add semantic annotations to the wiki. While this first appears to make things more complex, it can also greatly simplify the structure of the wiki, help users to find more information in less time, and improve the overall quality and consistency of the wiki. A large number of related extensions have been created that extend the ability to edit, display and browse through the data stored by SMW: the term Semantic MediaWiki is sometimes used to refer to this entire family of extensions.
Proper citation: Semantic MediaWiki (RRID:SCR_006246) Copy
https://github.com/RGLab/pepStat
Software for statistical analysis of peptide microarrays. It uses an integrated analytical method for analyzing peptide microarray antibody binding data, from normalization through subject-specific positivity calls and data integration and visualization.
Proper citation: pepStat (RRID:SCR_006240) Copy
http://pathogenseq.lshtm.ac.uk/estmoi
A per-based software to estimate multiplicity of infection (MOI) in parasite genomic sequence data. It is primarily developed to address the limitations of current laboratory (PCR) based estimates of multiplicity using high throughput sequence data. It requires a BAM (alignment output of short reads to the reference genome), VCF (a file with information on variant calls) and FASTA (reference genome) files. # Short reads are aligned to a reference genome using BWA, BOWTIE, SMALT or other short read aligners to generate a BAM file. # Single Nucleotide Polymorphisms (SNPs) are then identified using SAMTools/BCFtools and stored in the VCF format. # The reference FASTA file is expected to be indexed using ''samtools faidx'' to generate a *.fai file. estMOI generates files containing MOI estimates for each SNP combinations (file with name *.log) and a summary for all chromosomes (file with name *.txt).
Proper citation: estMOI (RRID:SCR_006192) Copy
An Antibody supplier who also provides assay services and products.
Proper citation: R and D Systems (RRID:SCR_006140) Copy
http://www.guthyjacksonfoundation.org/
The Guthy-Jackson Charitable Foundation is dedicated to funding basic science research to find answers that will lead to the prevention, clinical treatment programs and a potential cure for Neuromyelitis Optica (NMO) Spectrum Disease. The decision to create our Foundation came from a personal family crisis. Our daughter was officially diagnosed with NMO in June 2008. Since that time, we have met with many clinicians and researchers in order to understand what this means for our beautiful daughter and our family. Additionally, we have gathered and read every piece of information and NMO research article that is available on the Web. We are now beginning to understand that NMO is not only considered an orphan disease, but that very little research is available. We met with the All Greater Good Foundation in early July 2008 when it became clear that there is little-to-no funding available to research this rare and often misunderstood disease. We joined hands with the All Greater Good Foundation to immediately begin our work, and thus, The Guthy-Jackson Charitable Foundation was born. The Guthy-Jackson Charitable Foundation is dedicated to funding biomedical research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. It is our greatest hope that together we will reverse the effects of NMO and eventually cure this disease.
Proper citation: Guthy-Jackson Charitable Foundation (RRID:SCR_004441) Copy
MPI Research exists to provide comprehensive discovery, safety evaluation, bioanalytical, and analytical services that meet the requirements of biopharmaceutical, medical device, animal health, and chemical companies as we partner globally to bring safer and more effective products to the world. Our goal is to exceed the expectations of our Sponsors and maintain the highest respect in our industry by providing customized, responsive, and on-time services that add value to our Sponsors'' efforts to discover, develop, and enhance products in regulated international environments. We excel as a high performance, high quality organization because of our scientific knowledge and experience, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships. MPI Research has conducted thousands of drug safety, discovery, bioanalytical, and analytical studies. We offer extensive support and resources including, but not limited to * A wide and diverse range of classes of compounds * All routes of administration except inhalation * Studies with numerous species and models * Comprehensive reporting capabilities Flexibility and ample capacity enable us to * Accommodate multiple requirements simultaneously * Adjust schedules readily * Produce results quickly Responding to a broad spectrum of research needs: Working in partnership with pharmaceutical, biotech, medical device, and chemical companies, we conduct customized preclinical research throughout the discovery and development process, from early proof of concept testing to regulatory submissions, including IND, EPA/OPPTS, NDA, PMA, and 510K.
Proper citation: MPI Research (RRID:SCR_004397) Copy
http://www.cancer.gov/aboutnci/office-of-director
Proper citation: Office of the NCI Director (RRID:SCR_004391) Copy
An Antibody supplier
Proper citation: Cell Sciences (RRID:SCR_004502) Copy
https://www.cedarlanelabs.com/
An Antibody supplier
Proper citation: CEDARLANE Laboratories Limited (RRID:SCR_004462) Copy
The National Psoriasis Foundation (NPF) is a non-profit, voluntary health agency dedicated to finding a cure for psoriasis and psoriatic arthritis and eliminating their devastating effects through research, advocacy and education. Founded in 1966, the Psoriasis Foundation has evolved to become the leading patient advocacy group for the 7.5 million Americans living with psoriasis and psoriatic arthritis. As emerging research continues to demonstrate the serious, systemic effects of these chronic autoimmune diseases, our highest priority is to find a cure. Guided by our five year-strategic plan, we are moving towards this goal with an integrated approach that leverages the work of members, health care providers, advocates and scientists in four critical areas: * Research: ** Directly supporting the most promising early-stage research and emerging researchers. ** Hosting the world''s largest bank of psoriasis DNA samples. * Advocacy: ** Advancing a public policy agenda to secure more federal funding for psoriasis research. ** Improving access to care for patients. * Education: ** Providing extensive patient education. ** Keeping health care professionals up to date on psoriasis treatment. * Connection: ** Online communities, support networks, mentorship programs. ** Building a grassroots network of volunteers and advocates. * Leadership: ** A volunteer Board of Trustees steers the strategic direction of the National Psoriasis Foundation. ** Our Medical Board, made up of leading national psoriasis experts, provides medical guidance, leadership and advocacy. ** An executive staff of seasoned non-profit leaders drives the organization to achieve its strategic plan goals.
Proper citation: National Psoriasis Foundation (RRID:SCR_004454) Copy
A nonprofit organization offering research and clinical grade pluripotent stem cell lines, cytogenetic testing, quality control testing and cell banking services to researchers worldwide. The organization is focused on enhancing and expanding the study of human pluripotent stem cells by supporting basic research; establishing research protocols; creating and distributing cell lines; providing training to scientists worldwide; and supporting efforts to unlock the therapeutic potential of stem cell technologies. As home to the Wisconsin International Stem Cell (WISC) Bank, and previously the first US National Stem Cell Bank, WiCell serves the worldwide scientific stem cell community through banking, characterization, and distribution of stem cell lines as well as providing technical support. WiCell also offers cytogenetic services, quality control testing services and clinical grade cell lines to researchers across the globe.
Proper citation: WiCell Research Institute (RRID:SCR_004364) Copy
Cancer research and treatment center located in Buffalo, New York. Founded by surgeon Roswell Park in 1898, the center was the first in the United States to specifically focus on cancer research. The center is usually called Roswell Park in short.
Proper citation: Roswell Park Comprehensive Cancer Center (RRID:SCR_004471) Copy
http://www.sanger.ac.uk/resources/software/act/
A free tool for displaying pairwise comparisons between two or more DNA sequences. It can be used to identify and analyze regions of similarity and difference between genomes and to explore conservation of synteny, in the context of the entire sequences and their annotation. It is based on the software for Artemis, the genome viewer and annotation tool. ACT runs on UNIX, GNU/Linux, Macintosh and MS Windows systems. It can read complete EMBL and GENBANK entries or sequences in FASTA or raw format. Other sequence features can be in EMBL, GENBANK or GFF format.
Proper citation: ACT: Artemis Comparison Tool (RRID:SCR_004507) Copy
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