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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Biomarker Commons aggregates news and research on disease biomarkers, and includes links to biomarker journals, resources and commercial services. There are a number of biomarkers in use today, not only in experimental research but in the clinical setting. * Translation biomarkers are used in both a preclinical (i.e. animal models) and clinical setting * Early detection biomarkers are used to identify the earliest stages of disease onset * Diagnostic biomarkers are used to identify the presence or absence of a specific disease state * Staging biomarkers are used to distinguish between different stages of a chronic disorder * Prognostic biomarkers are used to determine patient survival probability * Disease biomarkers are related to a clinical outcome or measure of disease * Predictive or efficacy biomarkers are used to predict the efficacy of a specific drug therapy * Target biomarkers are used to determine the interaction of a drug or small molecule with its target * Mechanism biomarkers are used to report on the downstream effects of a drug * Toxicity biomarkers are used to determine the toxicological effects of drugs on an in vitro or in vivo system * Surrogate biomarkers are regarded as valid substitutes for measuring clinical outcomes Users may search biomarker news (search by tags, news archive. or insights), sign up for biomarker news email alerts, follow biomarker commons and view biomarker news top tags
Proper citation: Biomaker Commons (RRID:SCR_010645) Copy
http://www.ctmm.nl/en/programmas/infrastructuren/traitprojecttranslationeleresearch
An ambitious project to develop an IT infrastructure for translational research that aims to facilitate the collection, storage, analysis, archiving, sharing and securing of data.
Proper citation: TraIT (RRID:SCR_010493) Copy
A project that aims to improve access to human health data by developing a common information framework (EMIF-Platform) that allows for efficient re-use of existing health data, opening up new avenues of research for scientists. To ensure immediate applicability, the project includes two specific therapeutic research topics: the onset of Alzheimer's Disease (EMIF-AD) and metabolic complications of obesity (EMIF-Metabolics). The AD Topic aims to discover and validate biomarkers of AD onset in the preclinical and prodromal phase as well as for disease progression and identify high-risk individuals for therapeutic trials for prevention. The Metabolic Topic aims to discover and evaluate biomarkers for the risk of metabolic complications in obesity and to identify high-risk populations for intervention purposes. Collaboration between the 3 topics will ensure the development and delivery of an efficient Information Framework. This initiative has combined several data sets for neuroimaging including ADNI and several others, curating them into transmart.
Proper citation: EMIF (RRID:SCR_010495) Copy
http://www.bio.ifi.lmu.de/contextmap
A context-based approach to identify the most likely mapping for RNA-seq experiments.
Proper citation: ContextMap (RRID:SCR_010496) Copy
A biopharmaceutical company that focuses on central nervous system (CNS) diseases. The company is the result of a merger between Alkermes, Inc. and Elan Drug Technologies (EDT), the former drug formulation and manufacturing division of Elan Corporation, plc. The company is headquartered in Dublin, and has an R&D center in Waltham, Massachusetts and manufacturing facilities in Athlone, Ireland; Gainesville, Georgia; and Wilmington, Ohio. Alkermes has more than 20 commercial drug products and candidates that address serious and chronic diseases such as addiction, schizophrenia, diabetes and depression. Among these, five products are primary to the company: risperidone Long-Acting Injection (Risperdal Consta) for schizophrenia and bipolar 1 disorder, paliperidone palmitate (Invega Sustenna in the U.S., Xeplion in Europe) for schizophrenia, 4-aminopyridine (Ampyra in the U.S., Fampyra in Europe) to improve walking in patients with multiple sclerosis, naltrexone for extended-release injectable suspension (Vivitrol) for alcohol and opioid dependence, and exenatide extended-release for injectable suspension (Bydureon) for the treatment of type 2 diabetes. Bydureon is a once-weekly, long-acting form of the drug exenatide (Byetta) and was developed through a partnership between Amylin, Alkermes and Eli Lilly. It is approved in Europe and the U.S. (Wikipedia)
Proper citation: Alkermes (RRID:SCR_010497) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Integrated RNA-Seq read analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: CRAC (RRID:SCR_010652) Copy
https://www.creighton.edu/pharmacy-ot-pt
If Occupational Therapy, Pharmacy, or Physical Therapy is not just a career choice for you - if it''s a calling - then you may belong at Creighton University. For our students, it''s about more than career training. It''s about serving patients. Restoring health. Changing lives. Health care is a serious career, perhaps a lifelong calling. Creighton seeks the cream of the crop for these programs - men and women who feel a genuine calling to serve patients, restore health, and save lives. There''s more for you in Omaha than a vibrant university community. It''s true that U.S. News & World Report lists us as among the best colleges in the Midwest. And that we''ve been educating health professionals for more than a century. We''re also home to one of the world''s leading medical communities. That means training in leading edge facilities and in one of the nation''s best teaching hospitals. Perhaps our greatest distinction, however, is our university-wide commitment to creating an ever better and more just world. You''ll find our PT doctoral students staffing a free clinic for the underserved our pharmacy students conducting drug and alcohol education seminars ... and our OT students volunteering for the Special Olympics. It''s all tied to the values we strive toward as a Jesuit institution.
Proper citation: Creighton University School of Pharmacy and Health Professions (RRID:SCR_010541) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented September 15, 2017.
Funding opportunities provided by projects or organizations other than government funding opportunities such as those from NIH or NSF.
Proper citation: Community Pilot Funding Opportunity (RRID:SCR_010506) Copy
http://downsyndrome.ucsd.edu/index.php
The Down Syndrome Center for Research and Treatment (DSCRT) is one of the first programs in the country to connect academic research with treatment of adults and children with Down syndrome. Our goal is to apply cutting edge basic research to develop treatments that will help people with Down syndrome improve their cognition and forestall the onset of Alzheimer''s disease. Members of this special population continue to live fuller, healthier lives. We hope to build on this progress and advance their potential even further. About 400,000 people with Down syndrome live in the U.S. today, and one in every 733 babies is born with the condition. Children with Down syndrome are at risk for congenital heart defects, respiratory and hearing problems, childhood leukemia, and thyroid conditions. They typically also have mild to moderate cognitive impairment that affects learning, memory and speech. This is an important topic for research. With increased health care, education, and societal support, people with Down syndrome are living longer, fuller lives. But as they age we are discovering an increased occurrence of the symptoms associated with Alzheimer''s disease. In fact, about 25 percent of individuals with Down syndrome over age 35 increasingly show clinical signs and symptoms of Alzheimer''s type dementia. By age 60, more than half show cognitive decline.
Proper citation: Down Syndrome Center for Research and Treatment (RRID:SCR_010627) Copy
http://www.horizonpress.com/gateway/
Molecular Biology Gateway is the gateway to Web resources for molecular biology, genomics, PCR, protocols, microbiology, and biochemistry. Major categories include: Current Molecular Biology News, Microbiology, Virology, Genomics and Bioinformatics, PCR, Journals, Books, and other Publications, Protocols, Technology, Books, and Recommended Reading.
Proper citation: Molecular Biology Gateway (RRID:SCR_010628) Copy
http://icy.bioimageanalysis.org/
An open community platform for bioimage informatics providing the software resources to visualize, annotate and quantify bioimaging data. To bridge the gap between developers and users, it combines: a) an open-source image analysis software, offering a powerful and flexible environment for developers such as applied mathematicians to write algorithms fast and efficiently; b) a common set of tools to view and manipulate data, and a set of plugins to perform specific quantification or analysis on images; c) a community-based website centralizing all plugins and resources to facilitate their management and maximize their visibility towards users. Workspaces are virtual groups of plugins dedicated to a specific application or image processing domain. By downloading a workspace, ICY automatically installs all corresponding plugins. The workspaces are enabled, but the editing section is not ready yet. If you want to publish a plugin on this website, its code has to be GPL. Source code is available and provided in each application download.
Proper citation: icy (RRID:SCR_010587) Copy
Access service resource which connects labs needing and offering experimental services. Users can search for academic and government labs and experimental services, request and compare service quotes, and directly communicate with labs to arrange orders.
Proper citation: ScienceExchange (RRID:SCR_010620) Copy
A division of the Stanford University Libraries, which produces the online versions of journals and other scholarly content.
Proper citation: HighWire Press (RRID:SCR_000761) Copy
http://w3.cns.org/university/webinar/index2.asp
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 6,2023. A series of of webinars offered directly to users' computers. The webinars are offered in a variety of subjects, including neurotrauma, spine, tumor and vascular. Each webinars costs $35 US and offers CME credit.
Proper citation: University of Neurosurgery Webinar Series (RRID:SCR_000639) Copy
http://neuralensemble.org/neo/
A Python package for representing electrophysiology data, together with support for reading a wide range of neurophysiology file formats, including Spike2, NeuroExplorer, AlphaOmega, Axon, Blackrock, Plexon, Tdt, and support for writing to a subset of these formats plus non-proprietary formats including HDF5. The goal of Neo is to improve interoperability between Python tools for analyzing, visualizing and generating electrophysiology data (such as OpenElectrophy, NeuroTools, G-node, Helmholtz, PyNN) by providing a common, shared object model. In order to be as lightweight a dependency as possible, Neo is deliberately limited to represention of data, with no functions for data analysis or visualization. Neo implements a hierarchical data model well adapted to intracellular and extracellular electrophysiology and EEG data with support for multi-electrodes (for example tetrodes). Neo's data objects build on the quantities package, which in turn builds on NumPy by adding support for physical dimensions. Thus Neo objects behave just like normal NumPy arrays, but with additional metadata, checks for dimensional consistency and automatic unit conversion.
Proper citation: Neo (RRID:SCR_000634) Copy
http://www.icpsr.umich.edu/icpsrweb/NAHDAP/
Archive that acquires, preserves and disseminates data relevant to drug addiction and HIV research. Collection of data on drug addiction and HIV infection in United States. Most of datasets are raw data from surveys, interviews, and administrative records. They were originally gathered in research projects and for administrative purposes. Some datasets have been used in published studies. Bibliographies of these studies are available . Provides access to research data and technical assistance for data depositors. Provides e-workshops on data preparation and data systems.
Proper citation: National Addiction and HIV Data Archive Program (NAHDAP) (RRID:SCR_000636) Copy
http://athina.biol.uoa.gr/CAST/
A novel algorithm for low-complexity region detection and selective masking. The algorithm is based on multiple-pass Smith-Waterman comparison of the query sequence against twenty homopolymers with infinite gap penalties. The output of the algorithm is both the masked query sequence for further analysis, e.g. database searches, as well as the regions of low complexity.
Proper citation: CAST (RRID:SCR_000628) Copy
https://team.inria.fr/empenn/research/
Research team focused on research and development of new algorithms in medical imaging, information processing and computer assisted intervention in the context of the pathologies of the central nervous system. Research team jointly affiliated to INSERM (National Institute of Health and Scientific Research), Inria (National Institute of Research in Computer Sciences and Automation) and IRISA / UMR CNRS 6074, University of Rennes I. Multidisciplinary team merging researchers in image processing and medical doctors.
Proper citation: VISAGES Research (RRID:SCR_000749) Copy
http://www.helsinki.fi/bsg/software/BEBaC/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software for Bayesian estimation of bacterial communities.
Proper citation: BEBaC (RRID:SCR_000621) Copy
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